Probiotics and Antimicrobial Proteins




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Fermentation of Gluten by Lactococcus lactis LLGKC18 Reduces its Antigenicity and Allergenicity

Kamel-Eddine El Mecherfi, Roberta Lupi, Mehdi Cherkaoui, Marcela A. C. Albuquerque, Svetoslav Dimitrov Todorov, Olivier Tranquet, Caroline Klingebiel, Hélène Rogniaux, Sandra Denery-Papini, Bernard Onno, Bernadette Dora Gombossy de Melo Franco & Colette Larré 

doi : 10.1007/s12602-021-09808-1

Wheat is a worldwide staple food, yet some people suffer from strong immunological reactions after ingesting wheat-based products. Lactic acid bacteria (LAB) constitute a promising approach to reduce wheat allergenicity because of their proteolytic system.

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High and Economical Nattokinase Production with Acetoin as a Useful Byproduct from Soybean Milk and Glucose

Zijun Xiao, Jie Shen, Yang Li, Zhuo Wang, Yanshuang Zhao, Yong Chen & Jing-yi Zhao 

doi : 10.1007/s12602-021-09831-2

Nattokinase (NK) is a potent fibrinolytic enzyme with wide pharmaceutical and nutraceutical applications. Safe and high NK-yielding strains are urgently needed. In this study, the best strain NDF was isolated from one of the 11 natto samples and then identified as Bacillus subtilis.

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Probiotic Lactobacilli Administration Induces Changes in the Fecal Microbiota of Preweaned Dairy Calves

Sofía Fernández-Ciganda, Martín Fraga & Pablo Zunino 

doi : 10.1007/s12602-021-09834-z

Early microbial colonization is a determinant factor in animal health, and probiotic administration has been demonstrated to modulate intestinal microbiota and promote health in dairy calves.

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Safety Evaluation of Lactobacillus delbrueckii subsp. lactis CIDCA 133: a Health-Promoting Bacteria

Luís Cláudio Lima de Jesus, Thiago de Jesus Sousa, Nina Dias Coelho-Rocha, Rodrigo Profeta, Fernanda Alvarenga Lima Barroso, Mariana Martins Drumond, Pamela Mancha-Agresti, Ênio Ferreira, Bertram Brenig, Flávia Figueira Aburjaile & Vasco Azevedo 

doi : 10.1007/s12602-021-09826-z

Lactobacillus delbrueckii subsp. lactis CIDCA is a new potential probiotic strain whose molecular basis attributed to the host’s benefit has been reported. This study investigated the safety aspects of Lactobacillus delbrueckii subsp.

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Protective Effect of Levilactobacillus brevis Against Yersinia enterocolitica Infection in Mouse Model via Regulating MAPK and NF-κB Pathway

Ziqi Shi, Naiyu Guan, Weijiao Sun, Tianzhi Sun, Lingdi Niu, Jinyu Li & Junwei Ge 

doi : 10.1007/s12602-022-09957-x

Although the use of the probiotic bacterium Lactobacillus for the treatment and prevention of diseases caused by various pathogenic bacteria has received increasing attention in recent years, its mechanism remains incompletely understood.

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Enterocin M in Interaction in Broiler Rabbits with Autochthonous, Biofilm-Forming Enterococcus hirae Kr8 Strain

Andrea Lauková, Ľubica Chrastinová, Lenka Micenková, Eva Bino, Ivana Kubašová, Anna Kandri�áková, Soňa Gancar�íková, Iveta Plachá, Monika Holodová, Ľubomíra Grešáková, Zuzana Formelová & Monika Pogány Simonová 

doi : 10.1007/s12602-022-09941-5

Young rabbits are susceptible to gastrointestinal diseases caused by bacteria. Enterococcus hirae can be associated with diseases. But enterocins produced by some enterococcal species can prevent/reduce this problem.

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Analysis and Characterization of Lactobacillus paragasseri and Lacticaseibacillus paracasei: Two Probiotic Bacteria that Can Degrade Intestinal Oxalate in Hyperoxaluric Rats

Yogita Mehra, Nachiappa Ganesh Rajesh & Pragasam Viswanathan 

doi : 10.1007/s12602-022-09958-w

In the present study, we characterized the probiotic properties of two commercially available bacterial strains, Lactobacillus paragasseri UBLG-36 and Lacticaseibacillus paracasei UBLPC-87, and evaluated their ability to degrade oxalate in vitro and in a hyperoxaluria-induced nephrolithiasis rat model.

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Screening and Characterization of Some Lactobacillaceae for Detection of Cholesterol-Lowering Activities

Martin Frappier, Julie Auclair, Samir Bouasker, Sathursha Gunaratnam, Carine Diarra & Mathieu Millette 

doi : 10.1007/s12602-022-09959-9

Dyslipidemia, specifically abnormal levels of low-density lipoprotein cholesterol (LDL-C), is an important risk factor of cardiovascular disease. Evidence showing the promising abilities of probiotics to lower total cholesterol or LDL-C has, however, not yet convinced experts to recommend probiotic bacteria as treatment for blood lipid management.

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Treating the Onset of Diabetes Using Probiotics Along with Prebiotic from Pachyrhizus erosus in High-Fat Diet Fed Drosophila melanogaster

Amrita Bhanja, Nibedita Nayak, Sumit Mukherjee, Parag Prakash Sutar & Monalisa Mishra 

doi : 10.1007/s12602-022-09962-0

The increasing mortality due to hypertension and hypercholesterolemia is directly linked with type-2 diabetes. This shows the lethality of the disease. Reports suggest that the prebiotics along with probiotics help in lowering the effects of type-2 diabetes.

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Green Synthesized Silver Nanoparticles Using Lactobacillus Acidophilus as an Antioxidant, Antimicrobial, and Antibiofilm Agent Against Multi-drug Resistant Enteroaggregative Escherichia Coli

Padikkamannil Abishad, Jess Vergis, Varsha Unni, Vemula Prasastha Ram, Pollumahanti Niveditha, Jyothsana Yasur, Sanis Juliet, Lijo John, Kullaiya Byrappa, Prejit Nambiar, Nitin Vasantrao Kurkure, Sukhadeo Baliram Barbuddhe & Deepak Bhiwa Rawool 

doi : 10.1007/s12602-022-09961-1

The present study was envisaged to employ the green synthesis and characterization of silver nanoparticles (AgNPs) using the potential probiotic strain Lactobacillus acidophilus, to assess its antibacterial as well as antibiofilm activity against multi-drug-resistant enteroaggregative Escherichia coli (MDR-EAEC) strains and to investigate their antioxidant activity. In this study, AgNPs were successfully synthesized through an eco-friendly protocol, which was then confirmed by its X-ray diffraction (XRD) pattern.

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Staphylococcus epidermidis WF2R11 Suppresses PM2.5-Mediated Activation of the Aryl Hydrocarbon Receptor in HaCaT Keratinocytes

Eulgi Lee, Hyeok Ahn, Shinyoung Park, Gihyeon Kim, Hyun Kim, Myung-Giun Noh, Yunjae Kim, Jae-sung Yeon & Hansoo Park 

doi : 10.1007/s12602-022-09922-8

The skin supports a diverse microbiome whose imbalance is related to skin inflammation and diseases. Exposure to fine particulate matter (PM2.5), a major air pollutant, can adversely affect the skin microbiota equilibrium. In this study, the effect and mechanism of PM2.5 exposure in HaCaT keratinocytes were investigated.

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Psychobiotic Potential of Gamma-Aminobutyric Acid–Producing Marine Enterococcus faecium SH9 from Marine Shrimp

Shimaa El Sakkaa, Eman H. Zaghloul & Khaled M. Ghanem 

doi : 10.1007/s12602-022-09963-z

Psychobiotics are a novel class of probiotics with potential to confer mental wellness via production of neuroactive compounds such as gamma-aminobutyric acid (GABA). The demand for new biological sources of GABA has increased steadily.

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Lacticaseibacillus rhamnosus LS8 Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Tumorigenesis in Mice via Regulating Gut Microbiota and Inhibiting Inflammation

Tao Wang, Jiaqi Zheng, Shuchen Dong, Mohamedelfaieh Ismael, Yuanyuan Shan, Xin Wang & Xin Lü 

doi : 10.1007/s12602-022-09967-9

Gut microbiota dysbiosis may promote the process of colorectal cancer (CRC). Lacticaseibacillus rhamnosus LS8 (LRL) is a potential gut microbiota regulating strain because it can produce a novel antimicrobial substance (like cycloalanopine).

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Limosilactobacillus fermentum, Current Evidence on the Antioxidant Properties and Opportunities to be Exploited as a Probiotic Microorganism

Luciana Caroline Paulino do Nascimento, Diego Cabral Lacerda, Diorginis José Soares Ferreira, Evandro Leite de Souza & José Luiz de Brito Alves 

doi : 10.1007/s12602-022-09943-3

The unbalance in the production and removal of oxygen-reactive species in the human organism leads to oxidative stress, a physiological condition commonly linked to the occurrence of cancer, neurodegenerative, inflammatory, and metabolic disorders.

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Synbiotics: a New Route of Self-production and Applications to Human and Animal Health

Thi-Tho Nguyen, Phu-Tho Nguyen, Minh-Nhut Pham, Hary Razafindralambo, Quoc-Khanh Hoang & Huu-Thanh Nguyen 

doi : 10.1007/s12602-022-09960-2

Synbiotics are preparations in which prebiotics are added to probiotics to achieve superior performance and benefits on the host. A new route of their formation is to induce the prebiotic biosynthesis within the probiotic for synbiotic self-production or autologous synbiotics.

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