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Feasibility and effectiveness of time-restricted eating in different populations
Claire GreenhillÂÂ
doi : 10.1038/s41574-022-00770-8
Volume 18 Issue 12, December 2022
Non-nutritive sweeteners � too sweet to be wholesome?
Max Nieuwdorp & Hilde HerremaA
Timed high-fat diet feeding restores small bowel circadian rhythms
Samar A. Tolba & Vanessa A. LeoneA
Diagnosis of gestational diabetes mellitus: the debate continues
Aoife M. Egan & Fidelma P. DunneA
Pancreatic mesenchymal stem cells might protect β-cells
Rahul Khatri & Thomas LinnA
Strategies for modelling endometrial diseases
Alina R. Murphy, Hannes Campo & J. Julie KimA
doi : 10.1038/s41574-022-00725-z
Each month during a woman’s reproductive years, the endometrium undergoes vast changes to prepare for a potential pregnancy. Diseases of the endometrium arise for numerous reasons, many of which remain unknown. These endometrial diseases, including endometriosis, adenomyosis, endometrial cancer and Asherman syndrome, affect many women, with an overall lack of efficient or permanent treatment solutions.
Modelling metabolic diseases and drug response using stem cells and organoids
Wenxiang Hu & Mitchell A. LazarA
doi : 10.1038/s41574-022-00733-z
Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a major threat to health in the modern world, but efforts to understand the underlying mechanisms and develop rational treatments are limited by the lack of appropriate human model systems.
A global view of hypertensive disorders and diabetes mellitus during pregnancy
Li Jiang, Kun Tang, Laura A. Magee, Peter von Dadelszen, Alec Ekeroma, Xuan Li, Enyao Zhang & Zulfiqar A. BhuttaA
doi : 10.1038/s41574-022-00734-y
Two important maternal cardiometabolic disorders (CMDs), hypertensive disorders in pregnancy (HDP) (including pre-eclampsia) and gestational diabetes mellitus (GDM), result in a large disease burden for pregnant individuals worldwide. A global consensus has not been reached about the diagnostic criteria for HDP and GDM, making it challenging to assess differences in their disease burden between countries and areas.
