American Journal of Gastroenterology




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How I Approach It: Adrenal Insufficiency in Cirrhosis.

Wentworth, Brian J. MD 1; Henry, Zachary H. MD 1; Siragy, Helmy M. MD 2

doi : 10.14309/ajg.0000000000001939

Volume 117(12) pgs. 1889-2089 December 2022

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Diagnosis and Management of Gastroparesis.

Ramos, Gabriela Piovezani MD 1; Law, Ryan J. DO 1; Camilleri, Michael MD, DSc 1

doi : 10.14309/ajg.0000000000002003

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Imaging changes for a patient with ADPKD.

Tie, Jun PhD, MD 1; Yuan, Xulong BS 1

doi : 10.14309/ajg.0000000000001934

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Pancreatic Sarcomatoid Carcinoma With Intraductal Growth Protruding From the Papilla of Vater.

Harada, Yoshiyuki MD 1; Sakai, Arata MD, PhD 1; Ikegawa, Takuya MD, PhD 2; Shiomi, Hideyuki MD, PhD 3; Masuda, Atsuhiro MD, PhD 1; Kodama, Yuzo MD, PhD 1

doi : 10.14309/ajg.0000000000001929

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An Uncommon Cause of Gastric Perforation.

Wang, Lei MM 1; Zhang, Feng PhD 1; Lu, Qicheng MD 1

doi : 10.14309/ajg.0000000000001944

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A Case of Duodenal-Type Follicular Lymphoma.

Yin, Zhikun MD 1,2; Li, Ji MD 2; Zhang, Jinyan MD 1,2

doi : 10.14309/ajg.0000000000001952

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Endoscopic Resection of an Early-Stage Gastric Melanoma.

Goncalves, Margarida MD 1; Rebelo, Ana MD 1; Fernandes, Dalia MD 1; Costa, Dalila MD 1,2,3

doi : 10.14309/ajg.0000000000001971

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A Case of Jaundice and Gastric Outlet Obstruction in a Patient With a Billroth II Reconstruction and Gastric Neoplasia Solved by an Afferent Limb Endoscopic Ultrasound Gastrojejunostomy.

Mangiavillano, Benedetto MD 1,2; Auriemma, Francesco MD 1; Paduano, Danilo MD 1; Laura, Lamonaca MD 1; Spatola, Federica MD 1; Repici, Alessandro Prof 2,3

doi : 10.14309/ajg.0000000000001890

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A Novel Technique for Endoscopic Removal of a Large Foreign Body Incarcerated in the Colon Using a Modified Diameter-Adjustable Snare.

Fu, Sengwang MD 1,*; Mao, Yuqing MD 1,*; Yu, Yineng MD 1; Hu, Bin MD 1; Li, Baiwen MD, PhD 1

doi : 10.14309/ajg.0000000000001891

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Continuing Medical Education Questions: December 2022.

Bushyhead, Daniel W. MD

doi : 10.14309/ajg.0000000000002067

Early Liver Transplantation for Severe Alcohol-Associated Hepatitis and a History of Prior Liver Decompensation (C) The American College of Gastroenterology 2022. All Rights Reserved.

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Continuing Medical Education Questions: December 2022.

Shafi, Mehnaz A. MD

doi : 10.14309/ajg.0000000000002082

AB Article Title: Use of Benzodiazepines and Z-Drugs in Inflammatory Bowel Disease (C) The American College of Gastroenterology 2022. All Rights Reserved.

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GI Multisociety Strategic Plan on Environmental Sustainability.

Pohl, Heiko MD 1,2; de Latour, Rabia MD 3; Reuben, Adrian MBBS, MRCP 4; Ahuja, Nitin K. MD, MS 5; Gayam, Swapna MD, FACG 6; Kohli, Rohit MBBS, MS 7; Agrawal, Deepak MD, MPH, FACG 8; Omary, M. Bishr MD, PhD 9

doi : 10.14309/ajg.0000000000002031

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Immunotherapy for Cancer: Common Gastrointestinal, Liver, and Pancreatic Side Effects and Their Management.

Sedano, Rocio MD 1; Cabrera, Daniel MD, PhD 2,3; Jimenez, Andrea MD 4; Ma, Christopher MD 5; Jairath, Vipul MD, PhD 1,6; Arrese, Marco MD 2,7; Arab, Juan Pablo MD 1,2,7

doi : 10.14309/ajg.0000000000001983

AB Cancer cells can block the activation of T lymphocytes by deploying inhibitory signals to cell surface receptors that downregulate the immune response. Immune checkpoint inhibitors (ICI) are monoclonal antibodies that regulate the immune response by acting on these receptors.

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Gravity and the Gut: A Hypothesis of Irritable Bowel Syndrome.

Spiegel, Brennan MD, MSHS, FACG 1

doi : 10.14309/ajg.0000000000002066

AB The pathogenesis of irritable bowel syndrome (IBS)-a disorder of gut-brain interaction that affects up to 10% of the world's population-remains uncertain. It is puzzling that a disorder so prevalent and archetypal among humans can be explained by disparate theories, respond to treatments with vastly different mechanisms of action, and present with a dazzling array of comorbidities.

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Emerging Tools for Hepatocellular Carcinoma Surveillance.

Singal, Amit G. MD, MS 1; Reig, Maria MD 2,3,4,5; Villanueva, Augusto MD 6

doi : 10.14309/ajg.0000000000002015

AB Abdominal ultrasound, with or without alpha-fetoprotein, is the recommended strategy for hepatocellular carcinoma (HCC) surveillance but misses over one-third of HCC at an early stage.

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Principles for Assessing Quality of Life in Patients With Crohn's Disease.

Berenblum Tobi, Catalina BA 1

doi : 10.14309/ajg.0000000000002002

AB Crohn's disease (CD) is a lifelong inflammatory bowel disease that can severely impact quality of life. Many questionnaires exist to assess quality of life for patients with CD, but some of these questionnaires were developed without qualitative data from patients or include only limited symptoms.

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Diversity, Equity, and Inclusion in Gastroenterology and Hepatology: A Survey of Where We Stand.

Rahal, Harman K. MD 1,2,3,*; Tabibian, James H. MD, PhD 3,4,*; Issaka, Rachel MD 5,6; Quezada, Sandra MD, MS 7; Gray, Darrell II MD, MPH, FACG 8; Balzora, Sophie MD, FACG 9; Yang, Liu MD, MPH 1,3; Badiee, Jayraan MPH 1,3; May, Folasade MD, PhD, MPhil 1,3,10,11

doi : 10.14309/ajg.0000000000001984

In the setting of increasing attention to representation in medicine, we aimed to assess current perspectives of racial and ethnic workforce diversity and health care disparities among gastroenterology (GI) and hepatology professionals in the United States.

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Long-Term Outcomes of the Six-Food Elimination Diet and Food Reintroduction in a Large Cohort of Adults With Eosinophilic Esophagitis.

Zalewski, Angelika BS 1,*; Doerfler, Bethany MS, RDN 1,*; Krause, Amanda MD 1; Hirano, Ikuo MD 1; Gonsalves, Nirmala MD 1

doi : 10.14309/ajg.0000000000001949

Eosinophilic esophagitis (EoE) is an immune-mediated inflammatory condition with tissue eosinophilia resulting in esophageal dysfunction. The six-food elimination diet (SFED) is an EoE treatment approach that removes milk, wheat, soy, eggs, tree nuts/peanuts, and fish/shellfish. After histologic remission, food reintroduction occurs to identify a food trigger. Outcomes from large series of adults undergoing SFED and food reintroduction as clinical care are not known.

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Risk of Juvenile Idiopathic Arthritis and Rheumatoid Arthritis in Patients With Celiac Disease: A Population-Based Cohort Study.

Doyle, John B. MD 1; Lebwohl, Benjamin MD, MS 1; Askling, Johan MD, PhD 2; Forss, Anders MD 3; Green, Peter H.R. MD 1; Roelstraete, Bjorn PhD 3; Soderling, Jonas PhD 2; Ludvigsson, Jonas F. MD, PhD 1,3,4

doi : 10.14309/ajg.0000000000002014

Celiac disease (CD) is associated with many immune-mediated conditions, but a definitive epidemiological association between CD and juvenile idiopathic arthritis (JIA) or rheumatoid arthritis (RA) has not been established.

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Modified Cap-Assisted Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for the Treatment of Rectal Neuroendocrine Tumors <=10 mm: A Randomized Noninferiority Trial.

Gao, Xuelian MM 1,*; Huang, Shaohui MM 1,*; Wang, Yusi MM 1; Peng, Qun MM 1; Li, Weixin PhD 2; Zou, Yingying MM 1; Han, Zelong MD 1; Cai, Jianqun MD 1; Luo, Yuchen MD 1; Ye, Yaping MD 3; Li, Aimin MD 1; Bai, Yang MD 1; Chen, Ye MD 4,1; Liu, Side MD 1; Li, Yue MD 1

doi : 10.14309/ajg.0000000000001914

Although recent guidelines recommend endoscopic resection of rectal neuroendocrine tumors (NET) <=10 mm, there is no consensus on which endoscopic modality should be performed.

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Early Liver Transplantation for Severe Alcohol-Associated Hepatitis and a History of Prior Liver Decompensation.

Weinberg, Ethan M. MD, MS 1; Dukewich, Matthew MD, PharmD 2; Jakhete, Neha MD 3; Stonesifer, Elizabeth MD 3; Im, Gene Y. MD 4; Lucey, Michael R. MD 5; Shetty, Kirti MD 3; Rice, John P. MD 5; Victor, David W. III MD 6; Ghobrial, Mark R. MD, PhD 6; Shetty, Akshay MD 6; Rutledge, Stephanie M. MD 7; Florman, Sander S. MD 4; Hsu, Christine MD 8; Shoreibah, Mohamed MD 9; Aryan, Mahmoud MD 10; Orandi, Babak J. MD, PhD, MSc 11; Han, Hyosun MD 12; Terrault, Norah MD, MPH 12; Lee, Brian P. MD, MAS 12

doi : 10.14309/ajg.0000000000001901

In the published studies of early liver transplantation (LT) for alcohol-associated hepatitis (AH), patients with a prior liver decompensation are excluded. The appropriateness of this criteria is unknown.

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Combining FIB-4 and Liver Stiffness Into the FIB-5, a Single Model that Accurately Predicts Complications of Portal Hypertension.

Vutien, Philip MD, MS 1,2; Berry, Kristin PhD 3; Feng, Ziding PhD 4; VoPham, Trang PhD 4; He, Qianchuan PhD 4; Green, Pamela K. PhD 3; Ioannou, George N. BMBCh, MS 1,2,3

doi : 10.14309/ajg.0000000000001906

We aimed to combine the fibrosis (FIB)-4 score and fibroscan-derived liver stiffness (LS) into a single score (FIB-5) that predicts incident complications of portal hypertension (PH) in persons with compensated

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Comorbid Chronic Diseases and Survival in Compensated and Decompensated Cirrhosis: A Population-Based Study.

Asrani, Sumeet K. MD MSc 1; Hall, Lauren PhD 2; Reddy, Vikrant BA 2; Ogola, Gerald PhD 2; Izzy, Manhal MD 3

doi : 10.14309/ajg.0000000000001909

The burden of liver disease is substantial and increasing; the impact of comorbid chronic diseases on the clinical course of patients with compensated and decompensated cirrhosis is not well-defined. The aim of this study was to examine the individual and additive impact of comorbid chronic diseases on mortality in patients with cirrhosis.

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The Assessment of Driving Fitness Using an On-Road Evaluation in Patients With Cirrhosis.

Tandon, Puneeta MD 1,*; Pidborochynski, Tara MSc 2,*; Abraldes, Juan G. MD 1; Carbonneau, Michelle MN, NP 1; Newnham, Kimberly MN, NP 1; Bailey, Robert MD 3; Ismond, Kathleen P. MSc, MLIS 1; Bajaj, Jasmohan S. MD 4; Dobbs, Bonnie PhD 2

doi : 10.14309/ajg.0000000000001927

The association between cirrhosis and driving performance is of particular clinical relevance because of the life-threatening safety issues both for the driver with cirrhosis and the general public.

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Early-Life Mebendazole Exposure Increases the Risk of Adult-Onset Ulcerative Colitis: A Population-Based Cohort Study.

Agrawal, Manasi MD, MS 1,2; Allin, Kristine H. MD, PhD 1,3; Iversen, Aske T. MSc 1; Mehandru, Saurabh MD 2,4; Colombel, Jean-Frederic MD 2; Jess, Tine MD, DMSci 1,3

doi : 10.14309/ajg.0000000000001933

According to the hygiene hypothesis, exposure to parasites may protect against inflammatory bowel disease (IBD). Our aim was to examine the risk of IBD with childhood exposure to mebendazole, a broad-spectrum antihelminthic agent.

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Patient-Reported Impact of Symptoms in Crohn's Disease.

Varma, Anika BS 1; Weinstein, Jennifer MS 1; Seabury, Jamison BS 1; Rosero, Spencer BS 1; Wagner, Ellen MS 1; Zizzi, Christine MPA 1; Luebbe, Elizabeth MS 2; Dilek, Nuran MS 2; McDermott, Michael PhD 2; Heatwole, John 3; Saubermann, Lawrence MD 4; Temple, Larissa MD 5; Rogoff, Scott JD 6; Heatwole, Chad MD, MS-CI 1,2

doi : 10.14309/ajg.0000000000001954

Patients with Crohn's disease (CD) experience a variety of symptoms that significantly affect their lives. In this study, we (i) ascertain the most prevalent and impactful symptoms in CD and (ii) identify modifying factors that are associated with a higher disease burden in CD.

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Use of Benzodiazepines and Z-Drugs in Inflammatory Bowel Disease.

Bernstein, Charles N. MD 1,2; Fisk, John D. PhD 3; Walld, Randy BSc 4; Bolton, James M. MD 5; Sareen, Jitender MD 5; Patten, Scott B. MD, PhD 6; Singer, Alexander MB, BAO, Bch 7; Lix, Lisa M. PhD 8,2; Hitchon, Carol A. MD, MSc 1; El-Gabalawy, Renee PhD 9,3,2; Graff, Lesley A. PhD 9,2; Katz, Alan MBChB, MSc 10,4,7; Witges, Kelcie MPH 2; Marriott, James J. MD, MSc 1; Marrie, Ruth Ann MD, PhD 1,8,2; for the CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease

doi : 10.14309/ajg.0000000000001955

We estimated the incidence and prevalence of benzodiazepine and Z-drug (separately and jointly as BZD) use in the inflammatory bowel disease (IBD) population compared with matched controls without IBD and examined the association of mood/anxiety disorders (M/ADs) with the use of BZD from 1997 to 2017.

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Methanogens and Hydrogen Sulfide Producing Bacteria Guide Distinct Gut Microbe Profiles and Irritable Bowel Syndrome Subtypes.

Villanueva-Millan, Maria J. PhD 1; Leite, Gabriela PhD 1; Wang, Jiajing PhD 1; Morales, Walter BS 1; Parodi, Gonzalo BS 1; Pimentel, Maya L. BS 1; Barlow, Gillian M. PhD 1; Mathur, Ruchi MD 1,2; Rezaie, Ali MD, MS 1,3; Sanchez, Maritza BS 1; Ayyad, Sarah BS 1; Cohrs, Daniel MD 1; Chang, Christine RN 1; Rashid, Mohamad MBChB 1; Hosseini, Ava MPH 1; Fiorentino, Alyson BS 1; Weitsman, Stacy MS 1; Chuang, Brennan 1; Chang, Bianca MD 3; Pichetshote, Nipaporn MD 4; Pimentel, Mark MD 1,3

doi : 10.14309/ajg.0000000000001997

me (IBS) includes diarrhea-predominant (IBS-D) and constipation-predominant (IBS-C) subtypes. We combined breath testing and stool microbiome sequencing to identify potential microbial drivers of IBS subtypes.

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Low Performance of Hepatitis Delta Virus Testing Among 2 National Cohorts of Chronic Hepatitis B Patients in the United States.

Wong, Robert J. MD, MS 1,2; Kaufman, Harvey W. MD 3; Niles, Justin K. MS 3; Chen, Cheng MS 4; Yang, Zeyuan MPH 2; Kapoor, Hema MD 3; Cheung, Ramsey MD 1,2; Gish, Robert G. MD 5

doi : 10.14309/ajg.0000000000001947

The purpose of this study was to evaluate hepatitis delta virus (HDV) testing patterns among US adults with chronic hepatitis B (CHB). METHODS: HDV testing was evaluated among CHB patients using Quest Diagnostics (2016-2020) and Veterans Affairs (2010-2020) data

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Provider Beliefs, Practices, and Perceived Barriers to Dietary Elimination Therapy in Eosinophilic Esophagitis.

Chang, Joy W. MD, MS 1; Kliewer, Kara RD, PhD 2; Katzka, David A. MD 3; Peterson, Kathryn A. MD, MSc 4; Gonsalves, Nirmala MD 5; Gupta, Sandeep K. MD 6; Furuta, Glenn T. MD 7; Dellon, Evan S. MD, MPH 8

doi : 10.14309/ajg.0000000000001988

AB INTRODUCTION: Despite effective dietary treatments, physicians prefer medications for eosinophilic esophagitis (EoE). METHODS: We conducted a web-based survey of providers to assess the perceived effectiveness, practice patterns, and barriers to EoE dietary therapy.

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Longitudinal Assessment of Bile Duct Loss in Primary Biliary Cholangitis.

Hercun, Julian MD 1; Noureddin, Mazen MD, MHSc 1; Noureddin, Nabil MD 1; Eccleston, Jason MD 1; Woolridge, Daniel MD, MPH 1; Liang, T. Jake MD 1; Tana, Michele MD, MHSc 1; Kleiner, David E. MD, PhD 2; Rodriguez, Gracia Viana MD 1; Koh, Christopher MD, MHSc 1; Hoofnagle, Jay H. MD 1; Heller, Theo MD 1

doi : 10.14309/ajg.0000000000001985

Bile duct involvement is a key finding of primary biliary cholangitis (PBC). The aim of this study was to evaluate baseline ductopenia and disease progression. METHODS: Retrospective longitudinal histological follow-up of treatment-naive patients with PBC.

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Changes in Medicare Reimbursement for Common Gastroenterology Services Over 15 Years: 2007-2022.

Khunte, Mihir BS 1; Dang, Nhu BA 1; Zhong, Anthony BA 2; Kumar, Soryan BS 1; Kamp, Kendra PhD, RN 3; Shah, Samir A. MD, FACG 1,4,5

doi : 10.14309/ajg.0000000000002010

We evaluated trends in Medicare reimbursement for common gastrointestinal (GI) services from 2007 to 2022. METHODS: Top GI procedures and office/inpatient visits were identified.

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Calendar of Courses, Symposiums and Conferences.

doi : 10.14309/ajg.0000000000002049

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Letter to the Editor in Response to ACG Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease.

Haseeb, Muhammad MD; McCarty, Thomas R. MD, MPH; Jirapinyo, Pichamol MD, MPH; Thompson, Christopher C. MD, MSc

doi : 10.14309/ajg.0000000000001967

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Response to Haseeb et al.

Katz, Philip O. MD, MACG 1; Dunbar, Kerry B. MD, PhD 2,3; Schnoll-Sussman, Felice H. MD, FACG 1; Greer, Katarina B. MD, MS 4; Yadlapati, Rena MD, MSHS, FACG 5; Spechler, Stuart Jon MD, MACG 6,7

doi : 10.14309/ajg.0000000000002004

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Metabolic Syndrome and Estrogen Use Are Important Confounders in the Multifactorial Analysis of Colorectal Cancer Risk.

Scherubl, Hans PhD, MD 1

doi : 10.14309/ajg.0000000000002001

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Response to Scherubl.

Zhang, Yin MD, MPH 1; Giovannucci, Edward L. MD, ScD 1,2

doi : 10.14309/ajg.0000000000002005

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Detrimental Detection of Advanced Lesions With AI: False Confidence or Prevalence Bias?.

Hassan, Cesare MD 1,2; Mori, Yuichi MD 3,4; Sharma, Prateek MD 5; Spadaccini, Marco MD 2; Repici, Alessandro MD 1,2

doi : 10.14309/ajg.0000000000002023

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Response to Hassan et al.

Levy, Idan MD 1; Bruckmayer, Liora MD 2; Klang, Eyal MD 3; Ben-Horin, Shomron MD 1; Kopylov, Uri MD 1

doi : 10.14309/ajg.0000000000002033

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AIBD Abstracts 2022.

doi : 10.14309/ajg.0000000000002080

Volume 117 Supplement 2022 Advances in Inflammatory Bowel Diseases Annual Meeting Abstracts1 pgs. S1-S34 December 2022

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S1 Sarcopenia Is Associated With Social Determinants of Health in Patients With Inflammatory Bowel Disease.

Jain, Ayushi 1; Ramnath, Kavita 2; Rosales, Laurie 1; Kulow, Beth 1; Skeans, Jacob 1; Butnariu, Madalina 1; Afzali, Anita 3; Chiplunker, Adeeti 1

doi : 10.14309/01.ajg.0000897512.27046.ff

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S2 Predictor of Thromboembolic Complications in Patients With Ulcerative Colitis and Measures for Their Prevention.

Lishchinskaya, Albina 1; Knyazev, Oleg 1; Kagramanova, Anna 1; Noscova, Karina 1; Dudina, Galina 1; Kulakov, Dmitriy 1; Li, Irina 1

doi : 10.14309/01.ajg.0000897516.07603.13

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S3 IBD and Malignancy: Should Treatment Be Altered?.

Anudu, Azubuogu 1; Pinizzotto, Alexander 1; Ortiz, Donna 1; Pearce, Megan 1; Mhaskar, Rahul 1; Coughlin, Emily 1; Seminerio-Diehl, Jennifer 1

doi : 10.14309/01.ajg.0000897520.77876.6f

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S4 Patient Perspectives on the COVID-19 Pandemic, Its Impact on Inflammatory Bowel Disease Treatment, and Overall Well-Being One Year Later.

Charabaty, Aline 1; Schneider, Beth 2; Zambrano, Javier 3; Patel, Anish 4; Keefer, Laurie 5

doi : 10.14309/01.ajg.0000897524.18646.03

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S5 Characteristics and Outcomes of Patients With IBD Admitted to High vs Low Safety Net Burden Hospitals: A Nationwide Analysis.

Hans, Amneet 1; Das, Manjusha 2; Qayed, Emad 2

doi : 10.14309/01.ajg.0000897528.50896.47

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S6 Serrated Epithelial Change: To Follow or Not to Follow?.

Penmetsa, Amulya 1; Ryan, Charlotte 1; Marino, Danielle 1

doi : 10.14309/01.ajg.0000897532.71114.3b

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S7 Crohn's Disease: What to Do After Antitumour Necrosis Factor-[alpha] Therapy Fails?.

Ferreira, Ana Isabel 1; Lima Capela, Tiago 2; Macedo Silva, Vitor 2; Xavier, Sofia 2; Arieira, Catia 2; Curdia Goncalves, Tiago 2; de Castro, Francisca Dias 2; Moreira, Maria Joao 2; Cotter, Jose 2

doi : 10.14309/01.ajg.0000897536.83410.e1

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S8 How Can We Predict the Development of Antibodies to Infliximab in Crohn's Disease?.

Ferreira, Ana Isabel 1; Lima Capela, Tiago 2; Macedo Silva, Vitor 2; Xavier, Sofia 3; Arieira, Catia 2; Curdia Goncalves, Tiago 2; de Castro, Francisca Dias 2; Moreira, Maria Joao 2; Cotter, Jose 2

doi : 10.14309/01.ajg.0000897540.97592.66

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S9 Endoscopic Scores as Predictors of Treatment Failure in Ulcerative Colitis.

Ferreira, Ana Isabel 1; Lima Capela, Tiago 2; Xavier, Sofia 2; Arieira, Catia 2; Curdia Goncalves, Tiago 2; de Castro, Francisca Dias 2; Moreira, Maria Joao 2; Cotter, Jose 2

doi : 10.14309/01.ajg.0000897544.47554.b2

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S10 Management of Hyperlipidemia Induced by Primary Biliary Cholangitis.

Ahoussougbemey Mele, Ange 1; Mahmood, Riaz 1; Ogbuagu, Henry 1; Fombi, Jason 1

doi : 10.14309/01.ajg.0000897548.54402.30

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S11 Impact of Marijuana in Ulcerative Colitis With Nstemi Hospitalizations: Insights From National Inpatient Sample 2016-2019.

Watts, Abi 1; Jalal, Ayesha 2; Bhagat, Umesh 3; Thakral, Nimish 4; Raj, Kavin 5; Doukas, Sotirios 5; Patel, Pratik 5; Mohan, Karthik 6

doi : 10.14309/01.ajg.0000897552.46235.90

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S12 Development of Shingles on Tofacitinib Despite Completion of Recombinant VZV Vaccination Series.

Thomas, Braden 1; Moskow, Joshua 2; Garza, Manuel 1; Abraham, Bincy 3; Glassner, Kerri 1

doi : 10.14309/01.ajg.0000897556.94201.bb

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S13 Case Series: Upadacitinib as a Treatment for Crohn's Disease.

Thomas, Braden 1; Thurston, Theresa 2; Abraham, Bincy 3; Glassner, Kerri 1

doi : 10.14309/01.ajg.0000897560.45092.df

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S14 Duration of Response After Ozanimod Withdrawal: Phase 3 True North Study Results.

Sands, Bruce 1; Abraham, Bincy 2; Bressler, Brian 3; Reinisch, Walter 4; Jain, Anjali 5; Memaj, Arteid 5; Akukwe, Lucy 5; Jerry Liu, W. 5; Osterman, Mark 5; Canavan, James 5; Vermeire, Severine 6

doi : 10.14309/01.ajg.0000897564.25535.ec

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S15 Efficacy of Ozanimod in Patients With Ulcerative Colitis Who Were Previously Exposed to Vedolizumab: True North Post Hoc Analysis.

Sands, Bruce 1; Jain, Anjali 2; Harris, Ahmad 3; Osterman, Mark 2; Memaj, Arteid 2; Canavan, James 2; Axelrad, Jordan 4

doi : 10.14309/01.ajg.0000897568.71085.fb

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S16 Association of Quality of Life With Clinical Remission, HEMR, and Bowel Urgency in Patients With Ulcerative Colitis Treated With Mirikizumab.

Sands, Bruce 1; Wu, Jianmin 2; Sapin, Christophe 2; Gibble, Theresa Hunter 2; Kayhan, Cem 2; Schreiber, Stefan 3

doi : 10.14309/01.ajg.0000897572.27159.56

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S17 Treatment Patterns Among Moderate-to-Severe Ulcerative Colitis Patients in TARGET-IBD.

Cohen, Benjamin 1; Click, Benjamin 2; Barnes, Edward 3; Ungaro, Ryan 4; Gupte-Singh, Komal 5; Kumar, Jinender 5; Lawlor, Garrett 5; Canavan, James 5; Crawford, Julie 6; Munoz, Breda 6; Perez, Anthony 6; Morris, Heather 6; Long, Millie 3; Sands, Bruce 4

doi : 10.14309/01.ajg.0000897576.48867.c5

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S18 Crohn's Jejunoileitis in an Adult Patient With Prior Enterectomy After Necrotizing Enterocolitis: A Case Mandating Bowel Preserving Surgery.

Carnell, Casey 1; McHugh, Jacqueline 1; Lincango, Eddy 1; Holubar, Stefan 2

doi : 10.14309/01.ajg.0000897580.29305.ab

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S19 A Rare Case of Ileal Stricture in a Patient With Crohn's Disease.

Tan, Chin Kimg 1; Mun, Wang Lai 1; Wijaya, Ramesh 1; Chien, Jaime 1; Ang, Tiing Leong 1; Ong, Jeannie 1

doi : 10.14309/01.ajg.0000897584.93478.05

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S20 Impact of Anxiety on Patients With IBD: Insights From the National Inpatient Database (NIS)- 2015-2019.

Chhoun, Christopher 1; Blair, Brian 1; Joo, Lucy 1; Dasu, Neethi 1; Khalid, Yaser 2; Chiesa, Drew 1; Walters, Richard 1; Hashir, Mohammud 1; Suga, Herman 1

doi : 10.14309/01.ajg.0000897588.54411.b0

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S21 Hospital Outcomes in Depression and IBD: A Population Based Study.

Chhoun, Christopher 1; Joo, Lucy 1; Blair, Brian 1; Dasu, Neethi 1; Khalid, Yaser 2; Hashir, Mohammud 1; Walters, Richard 1; Suga, Herman 1; Chiesa, Drew 1

doi : 10.14309/01.ajg.0000897592.39171.bc

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S22 Outcomes of Patients With Inflammatory Bowel Disease and Alcohol Use From the National Inpatient Sample.

Chhoun, Christopher 1; Blair, Brian 1; Joo, Lucy 1; Hashir, Mohammud 1; Dasu, Neethi 1; Khalid, Yaser 2; Chiesa, Drew 1; Walters, Richard 1; Suga, Herman 1

doi : 10.14309/01.ajg.0000897596.13855.26

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S23 Outcomes of Patients With of IBD and concurrent NAFLD Versus IBD.

Chhoun, Christopher 1; Blair, Brian 1; Joo, Lucy 1; Hashir, Mohammud 1; Dasu, Neethi 1; Khalid, Yaser 2; Suga, Herman 1; Walters, Richard 1; Chiesa, Drew 1

doi : 10.14309/01.ajg.0000897600.72651.11

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S24 The Immunoprotective Effect of the Human Immunodeficiency Virus in Delaying the Development of Inflammatory Bowel Disease.

Miranda, Clive 1; Ali, Murad 1; Rana, Navpreet 1; Azad, Farhan 1; Ravi, Sasikanth 2; Warda, Katerina 3; Ravish, Nakul 1; Mahl, Thomas 1

doi : 10.14309/01.ajg.0000897604.04797.a2

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S25 Aseptic Hepatic Abscess Formation Via Inoculation From Crohn's Disease in a Patient on Adalimumab.

Miranda, Clive 1; Ali, Murad 1; Sparacino, Gina 1; Azad, Farhan 1; Ravi, Sasikanth 2; Warda, Katerina 3; Mahl, Thomas 1

doi : 10.14309/01.ajg.0000897608.82254.0c

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S26 Development of an Artificial Intelligence Tool for Detection of Polypoid Lesions in Inflammatory Bowel Disease (IBD-CADe).

Guerrero Vinsard, Daniela 1; Fetzer, Jeffrey 1; Agrawal, Upasana 1; Singh, Jassimran 1; Leggett, Cadman 1; Arunachalam, Shivaram 1; Raffals, Laura 1; Coelho Prabhu, Nayantara 1

doi : 10.14309/01.ajg.0000897612.99593.6b

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S27 Interobserver Agreement of Modified Paris Classification and Histology Prediction of Colorectal Lesions in Patients With Inflammatory Bowel Disease.

Guerrero Vinsard, Daniela 1; Lennon, Ryan 2; Bruining, David 1; East, James 2; Ebner, Derek 1; Kane, Sunanda 1; Kisiel, John 3; Leighton, Jonathan 4; Loftus, Edward Jr 5; Malik, Talha 6; Picco, Michael 7; Piovezani Ramos, Guilherme 1; Santiago, Priscila 1; Coelho Prabhu, Nayantara 1

doi : 10.14309/01.ajg.0000897616.43383.78

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S28 Efficacy and Safety of Tofacitinib in Moderate and Severe Ulcerative Colitis in Real Clinical Practice: 3 Years of Observation.

Podolskaya, Daria 1; Knyazev, Oleg 2; Kagramanova, Anna 2; Lishchinskaya, Albina 2; Nanaeva, Bella 3; Fadeeva, Nina; Kulakov, Dmitriy 2; Zvyaglova, Mariya 2; Li, Irina 2; Shkurko, Tatyana 4

doi : 10.14309/01.ajg.0000897620.45406.2e

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S29 Tobacco Cessation Counseling at Outpatient Visits for Crohn's Disease in the United States.

Holzer, David 1; Taylor, Matthew 1; Shivashankar, Raina 1

doi : 10.14309/01.ajg.0000897624.06730.1e

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S30 A Phase 2b Study to Evaluate the Efficacy and Safety of Investigational Microbiome Therapeutic SER-287 in Mildly-to-Moderately Active UC.

Feagan, Brian 1; Rubin, David 2; Hanauer, Stephen 3; Sandborn, William 4; Farooq, Shiraz 5; Levine, Henry 6; Oneto, Caterina 7; Lichter, David 8; Glick, Gabrielle 8; Brady, Kelly 8; McGovern, Barbara 8; Wang-Weigand, Sherry 8; Sostek, Mark 8; Grier, Lisa 8; Kerman, David 9; Misra, Bharat 10; Onwueme, Kenolisa 11; Axler, Jeffrey 12; von Moltke, Lisa 8

doi : 10.14309/01.ajg.0000897628.50103.7d

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S31 The Impact of Early vs Late Biologic Initiation Among Real-World Patients With Crohn's Disease in TARGET-IBD.

Long, Millie 1; Dubinsky, Marla 2; Regueiro, Miguel 3; Zambrano, Javier 4; Theigs, Cindy 4; Griffith, Jenny 4; Matthias, Wesley 4; Kujawski, Michelle 4; Sharma, Dolly 4; Pearson, Robert 4; Crawford, Julie 5; Dalfonso, Laura 5; Perez, Anthony 5; Gazis, Derek 5; Fried, Michael 5; Morris, Heather 5; Rubin, David 6

doi : 10.14309/01.ajg.0000897632.64570.56

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S32 Zonulin Concentration in Patients With Inflammatory Bowel Diseases With and Without COVID-19 Infection.

Kulakov, Dmitriy 1; Knyazev, Oleg 1; Kagramanova, Anna 1; Noscova, Karina 1; Babayan, Anait 1; Gudkova, Raisa 1; Parfenov, Asfold 1

doi : 10.14309/01.ajg.0000897636.88746.ec

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S33 Alpha-1 Antitrypsin is a Marker of Increased Intestinal Permeability in Ulcerative Colitis and COVID-19 Infection.

Kulakov, Dmitriy 1; Knyazev, Oleg 1; Lishchinskaya, Albina 1; Kagramanova, Anna 1; Noscova, Karina 1; Zvyaglova, Mariya 1; Shkurko, Tatyana 2; Nanaeva, Bella 3

doi : 10.14309/01.ajg.0000897640.00775.30

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S34 Evolving Trends and Concentrations in Inflammatory Bowel Disease Research 2000-2020.

Hajj Ali, Adel 1; Ribakow, Dovid 1; Click, Benjamin 2; Cohen, Benjamin 1

doi : 10.14309/01.ajg.0000897644.31733.7c

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S35 Transanal Ileal Pouch-anal Anastomosis for Inflammatory Bowel Disease (ta-IPAA): A Systematic Review and Meta-analysis.

Lincango, Eddy 1; Hernandez Dominguez, Oscar 1; Prien, Christopher 1; Duraes, Leonardo 1; Jia, Xue 1; Otero Pineiro, Ana 1; Uchino, Tairin 1; Liska, David 1; Kessler, Hermann 1; Bhama, Anuradha 1; Lavryk, Olga 1; Spivak, Anna 1; Valente, Michael 1; Lipman, Jeremy 2; Kanters, Arielle 2; Trunzo, Joseph 1; Hull, Tracy 2; Steele, Scott 2; Holubar, Stefan 2

doi : 10.14309/01.ajg.0000897648.75911.71

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S36 Idiopathic Myointimal Hyperplasia of the Mesenteric Veins a Rare Mimic of Inflammatory Bowel Disease: A Systematic Review.

Lincango, Eddy 1; Cheong, Ju Yong 1; Prien, Christopher 1; Hernandez Dominguez, Oscar 1; Tursun, Naz 1; Otero Pineiro, Ana 1; Lipman, Jeremy 2; Kessler, Hermann 1; Lightner, Amy 1; Bhama, Anuradha 1; Kanters, Arielle 2; Lavryk, Olga 1; Judeeba, Sami 1; Spivak, Anna 1; Valente, Michael 1; Trunzo, Joseph 1; Hull, Tracy 2; Steele, Scott 2; Holubar, Stefan 2

doi : 10.14309/01.ajg.0000897652.88162.12

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S37 Efficacy and Safety of Upadacitinib Maintenance Therapy in Patients With Moderately to Severely Active Crohn's Disease: U-ENDURE Phase 3 Results.

Panes, Julian 1; Loftus, Edward Jr 2; Lacerda, Ana 3; Peyrin-Biroulet, Laurent 4; D'Haens, Geert 5; Panaccione, Remo 6; Reinisch, Walter 7; Louis, Edouard 8; Chen, Minhu 9; Nakase, Hiroshi 10; Begun, Jakob 11; Boland, Brigid 12; Liu, Jianzhong 3; Dubcenco, Elena 3; Mohamed, Mohamed-Eslam 3; Feng, Tian 3; Colombel, Jean-Frederic 13

doi : 10.14309/01.ajg.0000897656.25080.34

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S38 On-Body Injector Administration of Risankizumab for Treatment of Moderate-to-Severe Crohn's Disease: Data From the Fortify Open-Label Longitudinal Real-Life Handling Substudy.

Loftus, Edward Jr 1; Griffith, Jenny 2; Neimark, Ezequiel 2; Song, Alexandra 2; Wallace, Kori 2; Nannapaneni, Sujani 2; Zhou, Ji 2; Andresen, Rachel 2; Kligys, Kristina 2; Liao, Xiaomei 2; Dubinsky, Marla 3

doi : 10.14309/01.ajg.0000897660.07812.b5

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S39 Use of Electronic Cigarettes in Inflammatory Bowel Disease: A Pilot Study.

Graziano, Elliot 1; Bittner, Krystle 1; Agyingi, Smith 2; Abdalla, Maisa 2

doi : 10.14309/01.ajg.0000897664.54427.71

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S40 The Impact of Nutritional Counseling on Growth Velocity in Pediatric IBD Patients.

Mathers, Emma 1; Patel, Mayher 1; Pescatello, Meredith 1; Saubermann, Lawrence 1

doi : 10.14309/01.ajg.0000897668.42156.13

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S41 Unusual Case of Tongue Deviation.

Demian, Ereny 1; Panganiban, Ronaldo Paolo 1

doi : 10.14309/01.ajg.0000897672.90706.0f

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S42 Combination Biological or Small Molecule Therapy in Refractory Crohn's Disease: A Multicenter Brazilian Experience.

Feitosa, Flavio 1; Parra, Rogerio 2; Queiroz, Natalia 3; Rosa, Carlos 4; Rzetelna, Heio 4; Khalil, Rogerio 5; Costa, Livia 5; Chebli, Liliana 5; Chebli, Julio 5

doi : 10.14309/01.ajg.0000897676.70683.bd

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S43 Serologic Response to SARS-CoV-2 Vaccines in an Ozanimod Open-Label Extension Study.

Caldera, Freddy 1; Maddux, Rachel 2; Ungaro, Ryan 3; Kaur, Amandeep 2; Brown, Elizabeth 2; Hu, Sarah 2; Sheffield, James 2; Silva, Diego 2; Harris, Sarah 2; Cree, Bruce 4

doi : 10.14309/01.ajg.0000897680.99103.0b

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S44 One Fell Swoop: Ozanimod for Ulcerative Colitis and Multiple Sclerosis.

Figueroa, Gabriela 1; Forster, Erin 1

doi : 10.14309/01.ajg.0000897684.92976.ec

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S45 Cancers Associated With Inflammatory Bowel Disease: A Population-Based Case-Control Study.

Coward, Stephanie 1; Murthy, Sanjay 2; Singh, Harminder 3; Benchimol, Eric 4; Kuenzig, Ellen 4; Kaplan, Gilaad 1

doi : 10.14309/01.ajg.0000897688.72993.4a

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S46 Persistent Risks of TNF Inhibitors Despite Benefits: 31 Years Old Pregnant Patient With Crohn's Disease.

Kaya, Gizem 1; Calderon Martinez, Evelyn 1; Zarandi, Nima 1; Aljassani, Khaldoon 1; Cinicola, John 1

doi : 10.14309/01.ajg.0000897692.91003.89

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S47 Combined Therapy With Ustekinumab and Vedolizumb in Severe Colitis in HIV Patients.

Chaves, Graciana 1; Ferreira, Guilherme 1; Alpes, Lucca 1; Falcao, Mirele 1; Coutinho, Clara 1; Ferraz, Tiago 1; Batista, Filipe 1

doi : 10.14309/01.ajg.0000897696.40388.7b

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S48 Health Disadvantage Is Associated With Persistent GI Symptoms in Adults With Crohn's Disease in Endoscopic Remission.

Tse, Chung Sang 1; Nguyen, Hang 2; Yonan, Aed 3; Dulai, Parambir 4; Gaidos, Jill 2; Valasek, Mark 1; Neill, Jennifer 1; Le, Helen 1; Collins, Angelina 1; Singh, Siddharth 1; Boland, Brigid 1

doi : 10.14309/01.ajg.0000897700.52187.00

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S49 Insurance Delays Biologic Treatment of Pediatric IBD in Tertiary Care Center.

Freid, Hannah 1; Spencer, Elizabeth 1

doi : 10.14309/01.ajg.0000897704.06716.d9

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