The Lancet Neurology




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Tackling the burden of stroke with primordial prevention

doi : 10.1016/S1474-4422(22)00443-4

Volume 21, Issue 12, December 2022, Page 1061

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Remote ischaemic conditioning for stroke prevention

Aravind Ganesh, Eric E Smith, *Michael D Hill

doi : 10.1016/S1474-4422(22)00438-0

Volume 21, Issue 12, December 2022, Pages 1062-1063

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Revisiting levodopa for advanced Parkinson's disease

Susan H Fox

doi : 10.1016/S1474-4422(22)00435-5

Volume 21, Issue 12, December 2022, Pages 1063-1065

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New results for risdiplam in spinal muscular atrophy

Susan T Iannaccone

doi : 10.1016/S1474-4422(22)00427-6

Volume 21, Issue 12, December 2022, Pages 1065-1066

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A new classification for diagnosis of optic neuritis

Steven L Galetta

doi : 10.1016/S1474-4422(22)00334-9

Volume 21, Issue 12, December 2022, Pages 1066-1068

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Good prospects for optic neuropathies

*Massimo Filippi, Maria A Rocca

doi : 10.1016/S1474-4422(22)00271-X

Volume 21, Issue 12, December 2022, Pages 1068-1070

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Ublituximab: a new anti-CD20 agent for multiple sclerosis

*Jiwon Oh, Amit Bar-Or

doi : 10.1016/S1474-4422(22)00446-X

Volume 21, Issue 12, December 2022, Pages 1070-1072

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COP27 Climate Change Conference: urgent action needed for Africa and the world

doi : 10.1016/S1474-4422(22)00430-6

Volume 21, Issue 12, December 2022, Pages 1073-1075

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Major advances in Parkinson's disease over the past two decades and future research directions

*Jose A Obeso, Mariana H G Monje, Michele Matarazzo

doi : 10.1016/S1474-4422(22)00448-3

Volume 21, Issue 12, December 2022, Pages 1076-1079

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Treatment of acute subdural haematoma

Nathan Beucler

doi : 10.1016/S1474-4422(22)00434-3

Volume 21, Issue 12, December 2022, Page 1080

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Treatment of acute subdural haematoma – Authors' reply

*Thomas A van Essen,Hester F Lingsma, Ewout W Steyerberg,Godard C W de Ruiter,Andrew I R Maas, Wilco C Peul

doi : 10.1016/S1474-4422(22)00433-1

Volume 21, Issue 12, December 2022, Pages 1080-1081

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A health literacy campaign for Parkinson's disease in Africa: a novel campaign to break down language barriers

*Mie Rizig, Omotola Thomas

doi : 10.1016/S1474-4422(22)00410-0

Volume 21, Issue 12, December 2022, Pages 1081-1082

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Correction to Lancet Neurol 2022; published online Sept 29. https://doi.org/10.1016/ S1474-4422(22)00309-X

doi : 10.1016/S1474-4422(22)00411-2

Volume 21, Issue 12, December 2022, Page e10

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Valérie Biousse: a leader in neuro-ophthalmology

Udani Samarasekera

doi : 10.1016/S1474-4422(22)00390-8

Volume 21, Issue 12, December 2022, Page 1083

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Maeike Zijlmans

doi : 10.1016/S1474-4422(22)00444-6

Volume 21, Issue 12, December 2022, Page 1084

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Franz Nissl's multiple contributions

Emmanuel Drouin, Arnaud Kwiatkowski,Patrick Hautecoeur

doi : 10.1016/S1474-4422(22)00445-8

Volume 21, Issue 12, December 2022, Page 1084

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Living with dementia: seeing the world and adapting to it

Jules Morgan

doi : 10.1016/S1474-4422(22)00391-X

Volume 21, Issue 12, December 2022, Pages 1085-1086

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The trailblazer Sir Victor Horsley: a celebrationMichael J Aminoff, Victor Horsley: The World's First Neurosurgeon and His Conscience, Cambridge University Press (2022), £64·79, ISBN: 978-1316513088

Eelco Wijdicks

doi : 10.1016/S1474-4422(22)00292-7

Volume 21, Issue 12, December 2022, Page 1087

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Delving into the human mind

Asal Golshaie

doi : 10.1016/S1474-4422(22)00392-1

Volume 21, Issue 12, December 2022, Page 1088

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Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham-controlled trial in China

Chengbei Hou*, Jing Lan*, Yinan Lin, Haiqing Song, Yuan Wang, Wenbo Zhao, Sijie Li, Ran Meng, Junwei Hao, Yuchuan Ding, Marc I Chimowitz,Marc Fisher, David C Hess, David S Liebeskind, Derek J Hausenloy, Jie Huang, Zhenguang Li, Xiujie Han, Jinbo Yang, Jin Zhou, Peimin Chen,Xinchen Zhu, Peilin Hu, Hongbo Pang, Wenwu Chen, Huisheng Chen, Guozhong Li, Dingbo Tao, Wei Yue, Zongen Gao, Xunming Ji, on behalf of theRICA investigators†

doi : 10.1016/S1474-4422(22)00335-0

Volume 21, Issue 12, December 2022, Pages 1089-1098

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Safety and efficacy of continuous subcutaneous foslevodopa-foscarbidopa in patients with advanced Parkinson's disease: a randomised, double-blind, active-controlled, phase 3 trial

Michael J Soileau, Jason Aldred, Kumar Budur, Nahome Fisseha, Victor SC Fung, Anna Jeong, Thomas E Kimber, Kevin Klos, Irene Litvan,Daniel O’Neill, Weining ZRobieson, Meredith A Spindler, David G Standaert, Saritha Talapala, Eleni Okeanis Vaou, Hui Zheng, Maurizio F Facheris,Robert A Hauser

doi : 10.1016/S1474-4422(22)00400-8

Volume 21, Issue 12, December 2022, Pages 1099-1109

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Safety and efficacy of risdiplam in patients with type 1 spinal muscular atrophy (FIREFISH part 2): secondary analyses from an open-label trial

Riccardo Masson, Maria Mazurkiewicz-Bedzińska, Kristy Rose, Laurent Servais, Hui Xiong, Edmar Zanoteli, Giovanni Baranello, Claudio Bruno,John W Day, Nicolas Deconinck, Andrea Klein, Eugenio Mercuri, Dmitry Vlodavets, Yi Wang, Angela Dodman, Muna El-Khairi, Ksenija Gorni,Birgit Jaber, Heidemarie Kletzl, Eleni Gaki, Paulo Fontoura, Basil T Darras, on behalf of the FIREFISH Study Group

doi : 10.1016/S1474-4422(22)00339-8

Volume 21, Issue 12, December 2022, Pages 1110-1119

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Diagnosis and classification of optic neuritis

Axel Petzold, ClareL Fraser,Mathias Abegg, Raed Alroughani, Daniah Alshowaeir, Regina Alvarenga, Cécile Andris, Nasrin Asgari, Yael Barnett,Roberto Battistella, Raed Behbehani, Thomas Berger, Mukharram M Bikbov, Damien Biotti, Valerie Biousse, Antonella Boschi, Milan Brazdil,Andrei Brezhnev, Peter A Calabresi, Monique Cordonnier, Fiona Costello, Franz M Cruz, Leonardo Provetti Cunha, Smail Daoudi,Romain Deschamps, Jerome deSeze, Ricarda Diem, Masoud Etemadifar, Jose Flores-Rivera, Pedro Fonseca, Jette Frederiksen, Elliot Frohman,Teresa Frohman, Caroline Froment Tilikete, Kazuo Fujihara, Alberto Gálvez, Riadh Gouider, Fernando Gracia, Nikolaos Grigoriadis,José M Guajardo, Mario Habek, Marko Hawlina, Elena H Martínez-Lapiscina, Juzar Hooker, Jyh Yung Hor, William Howlett, Yumin Huang-Link,Zhannat Idrissova, Zsolt Illes, Jasna Jancic, Panitha Jindahra, Dimitrios Karussis, Emilia Kerty, Ho Jin Kim, Wolf Lagrèze, Letizia Leocani,Netta Levin, Petra Liskova, Yaou Liu, Youssoufa Maiga, Romain Marignier, Chris McGuigan, Dália Meira, Harold Merle, Mário L R Monteiro,Anand Moodley, Frederico Moura, Silvia Muñoz, Sharik Mustafa, Ichiro Nakashima, Susana Noval, Carlos Oehninger, Olufunmilola Ogun,Afekhide Omoti, Lekha Pandit, Friedemann Paul, Gema Rebolleda, Stephen Reddel, Konrad Rejdak, Robert Rejdak, Alfonso J Rodriguez-Morales,Marie-Bénédicte Rougier, Maria Jose Sa, Bernardo Sanchez-Dalmau, Deanna Saylor, Ismail Shatriah, Aksel Siva, Hadas Stiebel-Kalish,Gabriella Szatmary, Linh Ta, Silvia Tenembaum, Huy Tran, Yevgen Trufanov, Vincent van Pesch, An-Guor Wang, Mike P Wattjes,Ernest Willoughby, Magd Zakaria, Jasmin Zvornicanin, Laura Balcer, Gordon T Plant

doi : 10.1016/S1474-4422(22)00200-9

Volume 21, Issue 12, December 2022, Pages 1120-1134

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Imaging of the optic nerve: technological advances and future prospects

Valérie Biousse, Helen V Danesh-Meyer, Amit M Saindane, Cédric Lamirel, Nancy J Newman

doi : 10.1016/S1474-4422(22)00173-9

Volume 21, Issue 12, December 2022, Pages 1135-1150

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The relevance of social and commercial determinants for neurological health

Sebastian Walsh*, Richard Merrick*, Carol Brayne

doi : 10.1016/S1474-4422(22)00428-8

Volume 21, Issue 12, December 2022, Pages 1151-1160

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Ca2+ Oscillations, Waves, and Networks in Islets From Human Donors With and Without Type 2 Diabetes

Marko Gosak; Richard Yan-Do; Haopeng Lin; Patrick E. MacDonald; Andraž Stožer

doi : 10.2337/db22-0004

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Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies

Kate M. Root; Brian Akhaphong; Melissa A. Cedars; Alexa M. Molin; Margaretta E. Huchthausen; Connor F. Laule; Ronald R. Regal; Emilyn U. Alejandro; Jean F. Regal

doi : 10.2337/db22-0404

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Dynamic Ins2 Gene Activity Defines β-Cell Maturity States

Chieh Min Jamie Chu; Honey Modi; Cara Ellis; Nicole A.J. Krentz; Søs Skovsø; Yiwei Bernie Zhao; Haoning Cen; Nilou Noursadeghi; Evgeniy Panzhinskiy; Xiaoke Hu; Derek A. Dionne; Yi Han Xia; Shouhong Xuan; Mark O. Huising; Timothy J. Kieffer; Francis C. Lynn; James D. Johnson

doi : 10.2337/db21-1065

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Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals With Presymptomatic Type 1 Diabetes

Bum Chul Kwon; Peter Achenbach; Vibha Anand; Brigitte I. Frohnert; William Hagopian; Jianying Hu; Eileen Koski; Ã…ke Lernmark; Olivia Lou; Frank Martin; Kenney Ng; Jorma Toppari; Riitta Veijola; on behalf of the T1DI Study Group

doi : 10.2337/db22-0360

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Stem Cell Therapy Improves Human Islet Graft Survival in Mice via Regulation of Macrophages

Wenyu Gou; Wei Hua; Lindsay Swaby; Wanxing Cui; Erica Green; Katherine A. Morgan; Charlie Strange; Hongjun Wang

doi : 10.2337/db22-0117

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Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2–Infected Young Individuals: Is It Type 1 Diabetes?

Massimo Pietropaolo; Peter Hotez; Nick Giannoukakis

doi : 10.2337/db21-0831

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Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease

Jiahao Liu; Viji Nair; Yi-yang Zhao; Dong-yuan Chang; Christine Limonte; Nisha Bansal; Damian Fermin; Felix Eichinger; Emily C. Tanner; Keith A. Bellovich; Susan Steigerwalt; Zeenat Bhat; Jennifer J. Hawkins; Lalita Subramanian; Sylvia E. Rosas; John R. Sedor; Miguel A. Vasquez; Sushrut S. Waikar; Markus Bitzer; Subramaniam Pennathur; Frank C. Brosius; Ian De Boer; Min Chen; Matthias Kretzler; Wenjun Ju; for the Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group

doi : 10.2337/db22-0169

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Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy

Nikolaus Hommer; Martin Kallab; Andreas Schlatter; Kinga Howorka; René M. Werkmeister; Doreen Schmidl; Leopold Schmetterer; Gerhard Garhöfer

doi : 10.2337/db22-0219

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Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-Induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages

Muneo Yamaguchi; Shintaro Nakao; Iori Wada; Tetsuya Matoba; Mitsuru Arima; Yoshihiro Kaizu; Mariko Shirane; Keijiro Ishikawa; Takahito Nakama; Yusuke Murakami; Masaharu Mizuochi; Wataru Shiraishi; Ryo Yamasaki; Toshio Hisatomi; Tatsuro Ishibashi; Masabumi Shibuya; Alan W. Stitt; Koh-Hei Sonoda

doi : 10.2337/db21-0247

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Incidence Trends of New-Onset Diabetes in Children and Adolescents Before and During the COVID-19 Pandemic: Findings From Florida

Yi Guo; Jiang Bian; Aokun Chen; Fei Wang; Amanda L. Posgai; Desmond A. Schatz; Elizabeth A. Shenkman; Mark A. Atkinson

doi : 10.2337/db22-0549

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Plasma Phospholipid Monounsaturated Fatty Acids and Gestational Diabetes Mellitus: A Longitudinal Study in the NICHD Fetal Growth Studies–Singletons Cohort

Kit Ying Tsoi; Yeyi Zhu; Jing Wu; Qi Sun; Stefanie N. Hinkle; Ling-Jun Li; Zhen Chen; Natalie L. Weir; Michael Y. Tsai; Ronald C.W. Ma; Cuilin Zhang

doi : 10.2337/db22-0241

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Sustained Proinflammatory Effects of Hypoglycemia in People With Type 2 Diabetes and in People Without Diabetes

Clementine E.M. Verhulst; Julia I.P. van Heck; Therese W. Fabricius; Rinke Stienstra; Steven Teerenstra; Rory J. McCrimmon; Cees J. Tack; Ulrik Pedersen-Bjergaard; Bastiaan E. de Galan; on behalf of the Hypo-RESOLVE consortium

doi : 10.2337/db22-0246

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Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes

Anna Syreeni; Emma H. Dahlström; Stefanie Hägg-Holmberg; Carol Forsblom; Marika I. Eriksson; Valma Harjutsalo; Jukka Putaala; Per-Henrik Groop; Niina Sandholm; Lena M. Thorn; on behalf of the FinnDiane Study Group

doi : 10.2337/db22-0327

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Neutrophil Extracellular Traps Induce Glomerular Endothelial Cell Dysfunction and Pyroptosis in Diabetic Kidney Disease

Fengfan Zheng; Linqiang Ma; Xuan Li; Zhihong Wang; Rufei Gao; Chuan Peng; Bing Kang; Yue Wang; Ting Luo; Jinshan Wu; Yi Yang; Lilin Gong; Qifu Li; Shumin Yang; Jinbo Hu

doi : 10.2337/db22-0153

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Morphological and Mechanical Properties of Lower-Limb Muscles in Type 2 Diabetes: New Potential Imaging Indicators for Monitoring the Progress of DPN

Yang Zurong; Li Yuandong; Tan Xiankui; Mo Fuhao; Liu Tang; Zhan Junkun

doi : 10.2337/db22-0009

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Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions

William P. Miller; Congzhou M. Sha; Siddharth Sunilkumar; Allyson L. Toro; Ashley M. VanCleave; Scot R. Kimball; Nikolay V. Dokholyan; Michael D. Dennis

doi : 10.2337/db22-0355

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Exercise-Linked Skeletal Irisin Ameliorates Diabetes-Associated Osteoporosis by Inhibiting the Oxidative Damage–Dependent miR-150-FNDC5/Pyroptosis Axis

Jyotirmaya Behera; Jessica Ison; Michael J. Voor; Neetu Tyagi

doi : 10.2337/db21-0573

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Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes

Samantha A. Crawford; Timothy A. Wiles; Janet M. Wenzlau; Roger L. Powell; Gene Barbour; Mylinh Dang; Jason Groegler; Jessie M. Barra; KaLia S. Burnette; Anita C. Hohenstein; Rocky L. Baker; Hubert M. Tse; Kathryn Haskins; Thomas Delong

doi : 10.2337/db22-0303

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Longitudinal Association of DNA Methylation With Type 2 Diabetes and Glycemic Traits: A 5-Year Cross-Lagged Twin Study

Xuanming Hong; Zhiyu Wu; Weihua Cao; Jun Lv; Canqing Yu; Tao Huang; Dianjianyi Sun; Chunxiao Liao; Yuanjie Pang; Zengchang Pang; Liming Cong; Hua Wang; Xianping Wu; Yu Liu; Wenjing Gao; Liming Li

doi : 10.2337/db22-0513

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Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2–Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656–2663

Chi-Kuei Hsu; Chih-Cheng Lai

doi : 10.2337/db22-0269

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Response to Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2– Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656–2663

Massimo Pietropaolo; Peter Hotez; Nick Giannoukakis

doi : 10.2337/db22-0347

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Comment on Liu et al. Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes. Diabetes 2022;71:722–732

Asimina Petsiou; George Vartholomatos; Agathocles Tsatsoulis; George K. Papadopoulos

doi : 10.2337/db22-0584

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