JAMA Oncology




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Five-Year Outcomes of FOLFIRINOX vs Gemcitabine as Adjuvant Therapy for Pancreatic CancerA Randomized Clinical Trial

Thierry Conroy, MD; Florence Castan, MSc; Anthony Lopez, MD; et al.

doi : 10.1001/jamaoncol.2022.3829

November 2022, Vol 8, No. 11, Pages 1543-1704

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Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer

Per E. Lønning, MD, PhD; Oleksii Nikolaienko, PhD; Kathy Pan, MD; et al.

doi : 10.1001/jamaoncol.2022.3846

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Expanded Parameters in Active Surveillance for Low-risk Papillary Thyroid CarcinomaA Nonrandomized Controlled Trial

Allen S. Ho, MD; Sungjin Kim, MS; Cynthia Zalt, MPH; et al.

doi : 10.1001/jamaoncol.2022.3875

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Differences in Cancer Phenotypes Among Frequent CHEK2 Variants and Implications for Clinical Care—Checking CHEK2

Brittany L. Bychkovsky, MD, MSc; Nihat B. Agaoglu, MD, PhD; Carolyn Horton, MS; et al.

doi : 10.1001/jamaoncol.2022.4071

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Short-term Outcomes of Laparoscopy-Assisted vs Open Surgery for Patients With Low Rectal CancerThe LASRE Randomized Clinical Trial

Wei-Zhong Jiang, MD; Jian-Min Xu, MD; Jia-Di Xing, MD; et al.

doi : 10.1001/jamaoncol.2022.4079

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Association of QTc Formula With the Clinical Management of Patients With Cancer

Daniel R. Richardson, MD, MSc; P. Christopher Parish, BS; Xianming Tan, PhD; et al.

doi : 10.1001/jamaoncol.2022.4194

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Association of Sinoatrial Node Radiation Dose With Atrial Fibrillation and Mortality in Patients With Lung Cancer

Kyung Hwan Kim, MD, PhD; Jaewon Oh, MD, PhD; Gowoon Yang, MD; Joongyo Lee, MD; Jihun Kim, PhD; Seo-yeon Gwak, MD;Iksung Cho, MD, PhD; Seung Hyun Lee, MD, PhD; Hwa Kyung Byun, MD, PhD; Hyo-Kyoung Choi, PhD;Jinsung Kim, PhD; Jee Suk Chang, MD, PhD; Seok-Min Kang, MD, PhD; Hong In Yoon, MD, PhD

doi : 10.1001/jamaoncol.2022.4202

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Incidence of Cutaneous Adverse Events With Phosphoinositide 3-Kinase Inhibitors as Adjuvant Therapy in Patients With CancerA Systematic Review and Meta-analysis

Abdulhadi Jfri, MSc, MD; Rachel Meltzer, MPH, MD; Arash Mostaghimi, MPH, MD;Nicole LeBoeuf, MPH, MD; Lauren Guggina, MD

doi : 10.1001/jamaoncol.2022.4327

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Treatment With Stereotactic Ablative Radiotherapy for Up to 5 Oligometastases in Patients With CancerPrimary Toxic Effect Results of the Nonrandomized Phase 2 SABR-5 Clinical Trial

Robert Olson, MD; Will Jiang, MD; Mitchell Liu, MD; Alanah Bergman, PhD; Devin Schellenberg, MD; Benjamin Mou, MD;Abraham Alexander, MD; Hannah Carolan, MD; Fred Hsu, MD; Stacy Miller, MD; Siavash Atrchian, MD;Elisa Chan, MD; Clement Ho, MD; Islam Mohamed, MD; Angela Lin, MD; Tanya Berrang, MD; Andrew Bang, MD;Nick Chng, PhD; Quinn Matthews, PhD; Sarah Baker, MD; Vicky Huang, PhD; Ante Mestrovic, PhD;Derek Hyde, PhD; Chad Lund, MD; Howard Pai, MD; Boris Valev, MD; Shilo Lefresene, MD; Scott Tyldesley, MD

doi : 10.1001/jamaoncol.2022.4394

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Assessment of Pretreatment and Posttreatment Evolution of Neurofilament Light Chain Levels in Patients Who Develop Immune Effector Cell–Associated Neurotoxicity Syndrome

Omar H. Butt, MD, PhD; Alice Y. Zhou, MD, PhD; Paolo F. Caimi, MD; Patrick H. Luckett, PhD; Julie K. Wisch, PhD;Paul-Robert Derenoncourt, MD; Kenneth Lee, BS; Gregory F. Wu, MD, PhD; Marcos J. G. de Lima, MD; Jian L. Campian, MD, PhD;Matthew J. Frank, MD, PhD; John F. DiPersio, MD, PhD; Armin Ghobadi, MD; Beau M. Ances, MD, PhD

doi : 10.1001/jamaoncol.2022.3738

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Changes in Opioid Prescriptions and Potential Misuse and Substance Use Disorders Among Childhood Cancer Survivors Following the 2016 Opioid Prescribing Guideline

Xin Hu, MSPH; Katharine E. Brock, MD, MS; Karen E. Effinger, MD, MS;Bo Zhang, PhD; Ilana Graetz, PhD; Joseph Lipscomb, PhD; Xu Ji, PhD

doi : 10.1001/jamaoncol.2022.3744

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Adoption of Extended-Interval Dosing of Single-Agent Pembrolizumab and Comparative Effectiveness vs Standard Dosing in Time-to-Treatment Discontinuation

Garth W. Strohbehn, MD, MPhil; Robert Holleman, MPH; Jennifer Burns, MS; Mandi L. Klamerus, MPH;Michael J. Kelley, MD; Eve A. Kerr, MD, MPH; Nithya Ramnath, MBBS; Timothy P. Hofer, MD, MSc

doi : 10.1001/jamaoncol.2022.4109

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Incidence Trends of Primary Cutaneous T-Cell Lymphoma in the US From 2000 to 2018A SEER Population Data Analysis

Zhuo Ran Cai, MDMichael L. Chen, BAMartin A. Weinstock, MD, PhDYoun H. Kim, MDRoberto A. Novoa, MDEleni Linos, MD, DrPH

doi : 10.1001/jamaoncol.2022.3236

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Evolution of Early-Phase Anticancer Drug Investigations in China

Shuhang Wang, MDYue Yu, MDYale Jiang, MDHuishan Zhang, MDPeiwen Ma, MDGang Liu, PhDNing Li, MD

doi : 10.1001/jamaoncol.2022.3856

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Inhibition of SARS-CoV-2 Omicron BA.1 and BA.4 Variants After Fourth Vaccination or Tixagevimab and Cilgavimab Administration in Patients With Cancer

the investigated variant of concern, with median inhibition ofMaximilian J. Mair, MDManfred Mitterer, MDPia Gattinger, PhDJulia M. BergerRudolf Valenta, MDDominic Fong, MDMatthias Preusser, MD

doi : 10.1001/jamaoncol.2022.4226

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Identification of Deaths Caused by Cancer and COVID-19 in the US During March to December 2020

Xuesong Han, PhDXin Hu, MSPHJingxuan Zhao, MPHAhmedin Jemal, DVM, PhDK. Robin Yabroff, PhD

doi : 10.1001/jamaoncol.2022.4315

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Surrogacy of Pathologic Complete Response in Trials of Neoadjuvant Therapy for Early Breast CancerCritical Analysis of Strengths, Weaknesses, and Misinterpretations

Fabio Conforti, MD; Laura Pala, MD; Vincenzo Bagnardi, PhD; Tommaso De Pas, MD; Marco Colleoni, MD;Marc Buyse, ScD, PhD; Gabriel Hortobagyi, MD, PhD; Luca Gianni, PhD; Eric Winer, MD, PhD;Sibylle Loibl, MD, PhD; Javier Cortes, MD, PhD; Martine Piccart, MD, PhD; Antonio C. Wolff, MD;Giuseppe Viale, PhD; Richard D. Gelber, PhD

doi : 10.1001/jamaoncol.2022.3755

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An Overview of Clinical Development of Agents for Metastatic or Advanced Breast Cancer Without ERBB2 Amplification (HER2-Low)

Aleix Prat, MD, PhD; Aditya Bardia, MD, MPH; Giuseppe Curigliano, MD, PhD; M. Elizabeth H. Hammond, MD;Sibylle Loibl, MD, PhD; Sara M. Tolaney, MD, MPH; Giuseppe Viale, MD

doi : 10.1001/jamaoncol.2022.4175

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Subacute Abdominal Pain in a Patient With Chronic Liver Disease and Hepatocellular Carcinoma

Binbin Zheng-Lin, MD, MSc; David M. Faleck, MD; James J. Harding, MD

doi : 10.1001/jamaoncol.2022.3888

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Early Death After Chemotherapy as a Quality Indicator—Is It Time to Bench the Benchmark?

Catherine Dunn, MBBS; Lucy Gately, MBBS, PhD; Peter Gibbs, MBBS, MD

doi : 10.1001/jamaoncol.2022.1856

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Ensuring High-Quality Shared Decision-making for Lung Cancer Screening

Robert J. Volk, PhD; Dawn Stacey, PhD

doi : 10.1001/jamaoncol.2022.3766

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Misinterpretation of Surgeons’ Statements on Cancer Removal—The Adverse Effects of “We Got It All�

Bonnie O. Wong, MD, PhD; Justin T. Clapp, PhD, MPH; Arden M. Morris, MD, MPH

doi : 10.1001/jamaoncol.2022.3769

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Keeping the Heartbeat Off-Target in Cancer Therapy

Benjamin N. Starobin, MD; Kevin F. Kwaku, MD, PhD

doi : 10.1001/jamaoncol.2022.4106

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Pushing the Envelope for Active Surveillance

Andrea L. Merrill, MD; Priya H. Dedhia, MD, PhD

doi : 10.1001/jamaoncol.2022.3809

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Defining a Therapeutic Ratio for Stereotactic Ablative Radiation Therapy in Oligometastatic Disease—Another Piece of the Puzzle

Matthew S. Katz, MD; Gregory A. Russo, MD

doi : 10.1001/jamaoncol.2022.4342

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The Body’s Scorecard

Diana Fishbein Launse, PhD

doi : 10.1001/jamaoncol.2022.1766

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The Unwritten Code

Anna W. LaVigne, MD

doi : 10.1001/jamaoncol.2022.4233

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Hereditary Cancer Syndromes—A Broader Clinical Spectrum Than Previously Understood?

Susrutha Puthanmadhom Narayanan, MBBS; Yana G. Najjar, MD

doi : 10.1001/jamaoncol.2022.3776

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Hereditary Cancer Syndromes—A Broader Clinical Spectrum Than Previously Understood?—Reply

Chenjie Zeng, PhD, MPH; Georgia L. Wiesner, MD, MS; Joshua C. Denny, MD, MS

doi : 10.1001/jamaoncol.2022.3779

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Etirinotecan Pegol Treatment for Patients With Metastatic Breast Cancer and Brain Metastases

Bin Zhang, MD; Shuixing Zhang, PhD

doi : 10.1001/jamaoncol.2022.4343

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Etirinotecan Pegol Treatment for Patients With Metastatic Breast Cancer and Brain Metastases—Reply

Debu Tripathy, MD; Sara M. Tolaney, MD; Mary Tagliaferri, MD

doi : 10.1001/jamaoncol.2022.4346

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Quantifying Clinical Utility of Adjuvant Abemaciclib in Patients With High-risk Early Breast Cancer Who Received Neoadjuvant Chemotherapy

Ryan Sun, PhD; Lee-Jen Wei, PhD

doi : 10.1001/jamaoncol.2022.4528

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Quantifying Clinical Utility of Adjuvant Abemaciclib in Patients With High-risk Early Breast Cancer Who Received Neoadjuvant Chemotherapy—Reply

Ran Jennifer Wei, PhD; Miguel Martin, MD, PhD; Stephen R. D. Johnston, MD, PhD

doi : 10.1001/jamaoncol.2022.4531

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