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Insulin Sensitization Following a Single Exercise Bout Is Uncoupled to Glycogen in Human Skeletal Muscle: A Meta-analysis of 13 Single-Center Human Studies
Janne R. Hingst; Johan D. Onslev; Stephanie Holm; Rasmus Kjøbsted; Christian Frøsig; Kohei Kido; Dorte E. Steenberg; Magnus R. Larsen; Jonas M. Kristensen; Christian Strini Carl; Kim Sjøberg; Farah S.L. Thong; Wim Derave; Christian Pehmøller; Nina Brandt; Glenn McConell; Jørgen Jensen; Bente Kiens; Erik A. Richter; Jørgen F.P. Wojtaszewski
doi : 10.2337/db22-0015
The Double Face of IRF4 in Metabolic Reprogramming
Abdualrahman Mohammed Abdualkader; Gary D. Lopaschuk; Rami Al Batran
doi : 10.2337/dbi22-0026
Yo-Yo Dieting: Mixed Messages for β-Cell Plasticity
Ke Ma; Sangeeta Dhawan
doi : 10.2337/dbi22-0024
Obese Skeletal Muscle–Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome
Ting Yao; Hongmei Yan; Xiaopeng Zhu; Qiongyue Zhang; Xingyu Kong; Shanshan Guo; Yonghao Feng; Hui Wang; Yinghui Hua; Jing Zhang; Steven D. Mittelman; Peter Tontonoz; Zhenqi Zhou; Tiemin Liu; Xingxing Kong
doi : 10.2337/db22-0260
Plasma Exosomal miRNAs Associated With Metabolism as Early Predictor of Gestational Diabetes Mellitus
Zhixin Ye; Songzi Wang; Xiaoqing Huang; Peisong Chen; Langhui Deng; Shiqi Li; Suiwen Lin; Zilian Wang; Bin Liu
doi : 10.2337/db21-0909
Liver-Derived S100A6 Propels β-Cell Dysfunction in NAFLD
Surbhi Dogra; Debajyoti Das; Sujay K. Maity; Avishek Paul; Priya Rawat; P. Vineeth Daniel; Kausik Das; Souveek Mitra; Partha Chakrabarti; Prosenjit Mondal
doi : 10.2337/db22-0056
TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance
Cagri Bodur; Dubek Kazyken; Kezhen Huang; Aaron Seth Tooley; Kae Won Cho; Tammy M. Barnes; Carey N. Lumeng; Martin G. Myers, Jr.; Diane C. Fingar
doi : 10.2337/db22-0256
Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Mice With Diet-Induced Obesity
Nathan C. Winn; Matthew A. Cottam; Monica Bhanot; Heather L. Caslin; Jamie N. Garcia; Rafael Arrojo e Drigo; Alyssa H. Hasty
doi : 10.2337/db22-0161
MC4R Deficiency Causes Dysregulation of Postsynaptic Excitatory Synaptic Transmission as a Crucial Culprit for Obesity
Xiaohui Wang; Xiaoli Cui; Yang Li; Fei Li; Yue Li; Jinye Dai; Han Hu; Xuefeng Wang; Jianyuan Sun; Yan Yang; Shuli Zhang
doi : 10.2337/db22-0162
MANF in POMC Neurons Promotes Brown Adipose Tissue Thermogenesis and Protects Against Diet-Induced Obesity
Qin Tang; Qinhui Liu; Jiahui Li; Jiamin Yan; Xiandan Jing; Jinhang Zhang; Yan Xia; Ying Xu; Yanping Li; Jinhan He
doi : 10.2337/db21-1128
miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo
Wenyi Luo; Youngsil Kim; Mary Ellen Jensen; Oana Herlea-Pana; Weidong Wang; Michael C. Rudolph; Jacob E. Friedman; Steven D. Chernausek; Shaoning Jiang
doi : 10.2337/db22-0205
Type 2 Diabetes, Independent of Obesity and Age, Is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells
Birgit Gustafson; Annika Nerstedt; Rosa Spinelli; Francesco Beguinot; Ulf Smith
doi : 10.2337/db22-0003
RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells
Xue Wen Ng; Yong Hee Chung; Farzad Asadi; Chen Kong; Alessandro Ustione; David W. Piston
doi : 10.2337/db21-1010
An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β-Cell Mass Acquisition
Alberto Bartolomé; Yann Ravussin; Junjie Yu; Anthony W. Ferrante, Jr.; Utpal B. Pajvani
doi : 10.2337/db22-0306
Impaired Glucagon-Mediated Suppression of VLDL-Triglyceride Secretion in Individuals With Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD)
Sara Heebøll; Jeyanthini Risikesan; Steffen Ringgaard; Indumathi Kumarathas; Thomas D. Sandahl; Henning Grønbæk; Esben Søndergaard; Søren Nielsen
doi : 10.2337/db22-0313
REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice
Siddharth Sunilkumar; Esma I. Yerlikaya; Allyson L. Toro; William P. Miller; Han Chen; Kebin Hu; Scot R. Kimball; Michael D. Dennis
doi : 10.2337/db22-0402
Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans
Zsu-Zsu Chen; Julian Avila Pacheco; Yan Gao; Shuliang Deng; Bennet Peterson; Xu Shi; Shuning Zheng; Usman A. Tahir; Daniel H. Katz; Daniel E. Cruz; Debby Ngo; Mark D. Benson; Jeremy M. Robbins; Xiuqing Guo; Magdalena del Rocio Sevilla Gonzalez; Alisa Manning; Adolfo Correa; James B. Meigs; Kent D. Taylor; Stephen S. Rich; Mark O. Goodarzi; Jerome I. Rotter; James G. Wilson; Clary B. Clish; Robert E. Gerszten
doi : 10.2337/db22-0033
Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)
Jinrui Cui; Gautam Ramesh; Martin Wu; Elizabeth T. Jensen; Osa Crago; Alain G. Bertoni; Chunxu Gao; Kristi L. Hoffman; Patricia A. Sheridan; Kari E. Wong; Alexis C. Wood; Yii-Der I. Chen; Jerome I. Rotter; Joseph F. Petrosino; Stephen S. Rich; Mark O. Goodarzi
doi : 10.2337/db22-0168
Disentangling Genetic Risks for Metabolic Syndrome
Eva S. van Walree; Iris E. Jansen; Nathaniel Y. Bell; Jeanne E. Savage; Christiaan de Leeuw; Max Nieuwdorp; Sophie van der Sluis; Danielle Posthuma
doi : 10.2337/db22-0478
Erratum. Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds. Diabetes 2015;64:243–256
Fanxing Xu; Badr Othman; Jason Lim; Angelika Batres; Bhaskar Ponugoti; Chenying Zhang; Leah Yi; Jian Liu; Chen Tian; Alhassan Hameedaldeen; Sarah Alsadun; Rohinton Tarapore; Dana T. Graves
doi : 10.2337/db22-er11a
