Age and Ageing




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Editor's view

Rowan H Harwood

doi : 10.1093/ageing/afac214

Age and Ageing, Volume 51, Issue 9, September 2022, afac214

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Promoting continence in older people

Mathias Schlögl, Martin H Umbehr, Muhammad Hamza Habib, Adrian Wagg, Adam L Gordon, Rowan Harwood

doi : 10.1093/ageing/afac199

Age and Ageing, Volume 51, Issue 9, September 2022, afac199

The prevalence of urinary incontinence (UI) is strongly associated with increasing age. Twenty five percent of women over 80 years of age have clinically significant symptoms in population surveys, but prevalence is as high as 70% in older hospital in-patients and residents of care homes with nursing.

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Dementia—so much done, so much to do, so much to gain by doing so

Sube Banerjee

doi : 10.1093/ageing/afac204

Age and Ageing, Volume 51, Issue 9, September 2022, afac204

it has been a busy 50 years for dementia, a complicated voyage from obscurity and neglect towards recognition, knowledge and action. This commentary sets out that path through research, practice and policy to examine what we have achieved, where we are now and what more there is to be done.

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Sarcoidosis in the older person: diagnostic challenges and treatment consideration

Michelle Brennan, David Breen

doi : 10.1093/ageing/afac203

Age and Ageing, Volume 51, Issue 9, September 2022, afac203

Sarcoidosis is a multi-system disorder with an increasing propensity to present in older patients. Diagnostic uncertainty is common and understandable given the higher prevalence of co-morbidities in older patients and broad differential for multi-system clinical presentations. Excluding malignancy and infection with a high degree of certainty is challenging and may require repeated confirmatory investigation where the diagnosis remains in doubt.

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New horizons for caring for people with dementia in hospital: the DEMENTIA CARE pointers for service change

Rebecca A Abbott, Morwenna Rogers, Ilianna Lourida, Colin Green, Susan Ball, Anthony Hemsley, Debbie Cheeseman, Linda Clare, Darren Moore, Chrissey Hussey, George Coxon, David J Llewellyn, Tina Naldrett, Jo Thompson Coon

doi : 10.1093/ageing/afac190

Age and Ageing, Volume 51, Issue 9, September 2022, afac190

Approximately two-thirds of hospital admissions are older adults and almost half of these are likely to have some form of dementia. People with dementia are not only at an increased risk of adverse outcomes once admitted, but the unfamiliar environment and routinised practices of the wards and acute care can be particularly challenging for them, heightening their confusion, agitation and distress further impacting the ability to optimise their care.

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Non-pharmacologic and pharmacologic treatments for anxiety in long-term care: a systematic review and meta-analysis

Kayla Atchison, Jennifer A Watt, Delaney Ewert, Ann M Toohey, Zahinoor Ismail, Zahra Goodarzi

doi : 10.1093/ageing/afac195

Age and Ageing, Volume 51, Issue 9, September 2022, afac195

older adults living in long-term care (LTC) commonly suffer from anxiety symptoms and disorders. We completed a systematic review and meta-analysis to identify efficacious treatments for anxiety symptoms for older adults living in LTC.

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Medication reviews and deprescribing as a single intervention in falls prevention: a systematic review and meta-analysis

Lotta J Seppala, Nellie Kamkar, Eveline P van Poelgeest, Katja Thomsen, Joost G Daams, Jesper Ryg, Tahir Masud, Manuel Montero-Odasso, Sirpa Hartikainen, Mirko Petrovic, Nathalie van der Velde, the Task Force on Global Guidelines for Falls in Older Adults

doi : 10.1093/ageing/afac191

Age and Ageing, Volume 51, Issue 9, September 2022, afac191

our aim was to assess the effectiveness of medication review and deprescribing interventions as a single intervention in falls prevention.

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How do predisposing factors differ between delirium motor subtypes? A systematic review and meta-analysis

Erica S Ghezzi, Danielle Greaves, Monique S Boord, Daniel Davis, Sara Knayfati, Jack M Astley, Rhianna L S Sharman, Stephanie I Goodwin, Hannah A D Keage

doi : 10.1093/ageing/afac200

Age and Ageing, Volume 51, Issue 9, September 2022, afac200

Delirium is a common neurocognitive disorder in hospitalised older adults with vast negative consequences. The predominant method of subtyping delirium is by motor activity profile into hypoactive, hyperactive and mixed groups.

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Preprocedural muscle strength and physical performance and the association with functional decline or mortality in frail older patients after transcatheter aortic valve implementation: a systematic review and meta-analysis

Dennis van Erck, Christine D Dolman, Jacqueline Limpens, Wilma J M Scholte op Reimer, José P Henriques, Ronak Delewi, Josje D Schoufour

doi : 10.1093/ageing/afac211

Age and Ageing, Volume 51, Issue 9, September 2022, afac211

A significant number of older patients planned for transcatheter aortic valve implantation (TAVI) experience a decline in physical functioning and death, despite a successful procedure.

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World guidelines for falls prevention and management for older adults: a global initiative

Manuel Montero-Odasso, Nathalie van der Velde, Finbarr C Martin, Mirko Petrovic, Maw Pin Tan, Jesper Ryg, Sara Aguilar-Navarro, Neil B Alexander, Clemens Becker, Hubert Blain, Robbie Bourke, Ian D Cameron, Richard Camicioli, Lindy Clemson, Jacqueline Close, Kim Delbaere, Leilei Duan, Gustavo Duque, Suzanne M Dyer, Ellen Freiberger, David A Ganz, Fernando Gómez, Jeffrey M Hausdorff, David B Hogan, Susan M W Hunter, Jose R Jauregui, Nellie Kamkar, Rose-Anne Kenny, Sarah E Lamb, Nancy K Latham, Lewis A Lipsitz, Teresa Liu-Ambrose, Pip Logan, Stephen R Lord, Louise Mallet, David Marsh, Koen Milisen, Rogelio Moctezuma-Gallegos, Meg E Morris, Alice Nieuwboer, Monica R Perracini, Frederico Pieruccini-Faria, Alison Pighills, Catherine Said, Ervin Sejdic, Catherine Sherrington, Dawn A Skelton, Sabestina Dsouza, Mark Speechley, Susan Stark, Chris Todd, Bruce R Troen, Tischa van der Cammen, Joe Verghese, Ellen Vlaeyen, Jennifer A Watt, Tahir Masud, the Task Force on Global Guidelines for Falls in Older Adults

doi : 10.1093/ageing/afac205

Age and Ageing, Volume 51, Issue 9, September 2022, afac205

falls and fall-related injuries are common in older adults, have negative effects on functional independence and quality of life and are associated with increased morbidity, mortality and health related costs. Current guidelines are inconsistent, with no up-to-date, globally applicable ones present.

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Functional mobility decline and incident mild cognitive impairment and early dementia in community-dwelling older adults: the Singapore Longitudinal Ageing Study

Tze Pin Ng, Tih Shih Lee, Wee Shiong Lim, Mei Sian Chong, Philip Yap, Chin Yee Cheong, Iris Rawtaer, Tau Ming Liew, Xinyi Gwee, Qi Gao, Keng Bee Yap

doi : 10.1093/ageing/afac182

Age and Ageing, Volume 51, Issue 9, September 2022, afac182

Motor and gait disturbances are evident in early Alzheimer and non-Alzheimer dementias and may predict the likelihood of mild cognitive impairment (MCI) or progression to dementia.

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Long-term outcomes of stroke unit care in older stroke patients: a retrospective cohort study

Max Geraedts, Dijana Ebbeler, Nina Timmesfeld, Manfred Kaps, Klaus Berger, Björn Misselwitz, Christian Günster, Patrik Dröge, Michael Schneider

doi : 10.1093/ageing/afac197

Age and Ageing, Volume 51, Issue 9, September 2022, afac197

older patients are less frequently treated in stroke units (SUs). Clinicians do not seem convinced that older patients benefit from specialised treatment in SU similarly to younger patients.

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Low-density lipoprotein cholesterol in oldest old with acute myocardial infarction: Is lower the better?

Hui-Hui Liu, Meng Zhang, Run-Zhen Chen, Jin-Ying Zhou, Jie Qian, Ke-Fei Dou, Hong-Bing Yan, Jian-Jun Li

doi : 10.1093/ageing/afac202

Age and Ageing, Volume 51, Issue 9, September 2022, afac202

the relationship between low-density lipoprotein cholesterol (LDL-C) and adverse outcomes among the older people remains controversial.

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Family social support and stability of preferences regarding place of death among older people: a 3-year longitudinal study from the Japan Gerontological Evaluation Study

Kenjiro Kawaguchi, Kazushige Ide, Katsunori Kondo

doi : 10.1093/ageing/afac210

Age and Ageing, Volume 51, Issue 9, September 2022, afac210

it remains unclear how family relationships could affect stability of end-of-life care preferences.

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Psychotropic drug treatment for agitated behaviour in dementia: what if the guideline prescribing recommendations are not sufficient? A qualitative study

Margaretha T Dijk, Sarah Tabak, Cees M P M Hertogh, Rob M Kok, Rob J van Marum, Sytse U Zuidema, Eefje M Sizoo, Martin Smalbrugge

doi : 10.1093/ageing/afac189

Age and Ageing, Volume 51, Issue 9, September 2022, afac189

Agitation is a common challenging behaviour in dementia with a negative influence on patient’s quality of life and a high caregiver burden. Treatment is often difficult. Current guidelines recommend restrictive use of psychotropic drug treatment, but guideline recommendations do not always suffice.

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Screening for thyroid dysfunction with free T4 instead of thyroid stimulating hormone (TSH) improves efficiency in older adults in primary care

Madeleen Bosma, Robert S Du Puy, Bart E P B Ballieux

doi : 10.1093/ageing/afac215

Age and Ageing, Volume 51, Issue 9, September 2022, afac215

Subclinical hypothyroidism (SCHT) is defined as a consistently elevated thyroid stimulating hormone (TSH) with a free T4 (fT4) within the reference range. This diagnosis may lead to additional monitoring, levothyroxine therapy and increased patient concerns, despite lack of evidence of treatment benefit in older adults. In order to avoid this diagnosis, we evaluated the efficiency of fT4-based screening for thyroid dysfunction, in older adults in primary care and compared it with TSH-based screening.

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