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Spotlight on the October 18 Issue.

Merino, Jose G. MD, MPhil; Editor-in-Chief, Neurology(R)

doi : 10.1212/WNL.0000000000201219

Volume 99(16) pgs. 679-729,e1694-e1834 October 18, 2022

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The Challenging Puzzle of Migraine, Age, and Vascular Health.

Sacco, Simona MD; Sposato, Luciano A. MD, PhD

doi : 10.1212/WNL.0000000000201071

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Common Genetic Variants and Early Onset Stroke: Clues but No Answers.

Majersik, Jennifer Juhl MD, MS; Lacaze, Paul PhD

doi : 10.1212/WNL.0000000000200822

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Neuroimaging and Management of Pediatric Cancer Survivors Treated With Cranial Radiation: Consensus Recommendations When Evidence Is Sparse.

Brosius, Stephanie N. MD, PhD; Benedetti, Giulia M. MD; Beslow, Lauren A. MD, MSCE

doi : 10.1212/WNL.0000000000201138

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Vascular Risk Score and Associations With Past, Current, or Future Migraine in Women: Cohort Study.

Ibrahimi, Khatera MD *; Rist, Pamela M. ScD *; Carpenet, Claire MSc; Rohmann, Jessica L. MSc; Buring, Julie E. ScD; Maassen van den Brink, Antoinette PhD *; Kurth, Tobias MD, ScD *

doi : 10.1212/WNL.0000000000201009

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Nuclear Magnetic Resonance Spectroscopy Metabolomics in Idiopathic Intracranial Hypertension to Identify Markers of Disease and Headache.

Grech, Olivia MRes; Seneviratne, Senali Y. MBChB; Alimajstorovic, Zerin PhD; Yiangou, Andreas MBBS; Mitchell, James L. MBChB; Smith, Thomas B. PhD; Mollan, Susan P. MBcHB; Lavery, Gareth G. PhD; Ludwig, Christian PhD; Sinclair, Alexandra J. PhD

doi : 10.1212/WNL.0000000000201007

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Quality of Life Outcomes Over Time in Patients With Unruptured Intracranial Aneurysms With and Without Preventive Occlusion: A Prospective Cohort Study.

Algra, Annemijn M. MD; Greving, Jacoba P. PhD; Wermer, Marieke J.H. PhD; van Walderveen, Marianne A.A. PhD; van der Schaaf, Irene C. PhD; van der Zwan, Albert PhD; Visser-Meily, Johanna M.A. PhD; Rinkel, Gabriel J.E. FRCPE; Vergouwen, Mervyn D.I. PhD

doi : 10.1212/WNL.0000000000200831

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Development of the SAFETEA Scores for Predicting Risks of Complications of Preventive Endovascular or Microneurosurgical Intracranial Aneurysm Occlusion.

Algra, Annemijn M. MD; Greving, Jacoba P. PhD; de Winkel, Jordi MD; Kurtelius, Arttu PhD; Laban, Kamil PhD; Verbaan, Dagmar PhD; van den Berg, Rene PhD; Vandertop, William PhD; Lindgren, Antti PhD; Krings, Timo MD, PhD, FRCPC; Woo, Peter Y.M. PhD; Wong, George K.C. PhD; Roozenbeek, Bob MD, PhD; van Es, Adriaan C.G.M. MD, PhD; Dammers, Ruben MD, PhD; Etminan, Nima MD; Boogaarts, Hieronymus PhD; van Doormaal, Tristan PhD; van der Zwan, Albert PhD; van der Schaaf, Irene C. PhD; Rinkel, Gabriel J.E. FRCPE; Vergouwen, Mervyn D.I. PhD

doi : 10.1212/WNL.0000000000200978

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Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.

Jaworek, Thomas MS *; Xu, Huichun MD, PhD *; Gaynor, Brady J. MS; Cole, John W. MD, MS; Rannikmae, Kristiina MD, PhD; Stanne, Tara M. PhD; Tomppo, Liisa MD, PhD; Abedi, Vida PhD; Amouyel, Philippe MD, PhD; Armstrong, Nicole D. MS, PhD; Attia, John MD, PhD; Bell, Steven PhD; Benavente, Oscar R. MD; Boncoraglio, Giorgio B. MD; Butterworth, Adam PhD; for the Cervical Artery Dissections and Ischemic Stroke Patients (CADSIP) Consortium; Carcel-Marquez, Jara MSc; Chen, Zhengming DPhil; Chong, Michael PhD, MSc; Cruchaga, Carlos PhD; Cushman, Mary MD, MSc; Danesh, John FMedSci, DPhil; Debette, Stephanie MD, PhD; Duggan, David J. PhD; Durda, Jon Peter PhD; Engstrom, Gunnar MD, PhD; Enzinger, Chris MD; Faul, Jessica D. PhD, MPH; Fecteau, Natalie S. MPH; Fernandez-Cadenas, Israel MD, PhD; Gieger, Christian PhD; Giese, Anne-Katrin MD; Grewal, Raji P. MD; Grittner, Ulrike PhD; Havulinna, Aki S. DSc; Heitsch, Laura MD; Hochberg, Marc C. MD; Holliday, Elizabeth BSc, MSc, PhD; Hu, Jie MD, PhD; Ilinca, Andreea MD, PhD; for the INVENT Consortium; Irvin, Marguerite R. PhD; Jackson, Rebecca D. MD; Jacob, Mina A. MD; Rabionet, Raquel PhD; Jimenez-Conde, Jordi MD, PhD; Johnson, Julie A. PharmD; Kamatani, Yoichiro MD, PhD; Kardia, Sharon L.R. PhD; Koido, Masaru PhD; Kubo, Michiaki MD, PhD; Lange, Leslie PhD; Lee, Jin-Moo MD, PhD; Lemmens, Robin MD, PhD; Levi, Christopher R. MD, PhD; Li, Jiang PhD; Li, Liming MPH; Lin, Kuang PhD; Lopez, Haley BS; Luke, Sothear MPH; Maguire, Jane PhD; McArdle, Patrick F. PhD; McDonough, Caitrin W. PhD; Meschia, James F. MD; Metso, Tiina MD, PhD; Muller-Nurasyid, Martina PhD; O'Connor, Timothy D. PhD; O'Donnell, Martin PhD; Peddareddygari, Leema R. MBBS, MD; Pera, Joanna MD, PhD; Perry, James A. PhD; Peters, Annette PhD; Putaala, Jukka MD, PhD; Ray, Debashree BSc, MStat, PhD; Rexrode, Kathryn MD, MPH; Ribases, Marta BSc, PhD; Rosand, Jonathan MD, MSc; Rothwell, Peter M. MD, PhD, FMedSci; Rundek, Tatjana MD, PhD; Ryan, Kathleen A. MPH; Sacco, Ralph L. MD, MS; Salomaa, Veikko MD, PhD; Sanchez-Mora, Cristina BSc, PhD; Schmidt, Reinhold MD; Sharma, Pankaj MD, PhD, FRCP; Slowik, Agnieszka MD, PhD; Smith, Jennifer A. PhD, MPH; Smith, Nicholas L. PhD, MPH; Wassertheil-Smoller, Sylvia PhD; Soderholm, Martin MD, PhD; Stine, O. Colin PhD; Strbian, Daniel MD, PhD; Sudlow, Cathie L.M. DPhil, FRCP(E); Tatlisumak, Turgut MD, PhD; Terao, Chikashi MD, PhD; Thijs, Vincent MD, PhD; Torres-Aguila, Nuria P. PhD; Tregouet, David-Alexandre PhD; Tuladhar, Anil M. MD; Veldink, Jan H. MD, PhD; Walters, Robin G. PhD; Weir, David R. PhD; Woo, Daniel MD; Worrall, Bradford B. MD, MSc; Hong, Charles C. MD, PhD; Ross, Owen A. PhD; Zand, Ramin MD, MPH; Leeuw, Frank-Erik de MD, PhD; Lindgren, Arne G. MD, PhD; Pare, Guillaume MD, MSc; Anderson, Christopher D. MD, MMSc; Markus, Hugh S. DM, FMed Sci; Jern, Christina MD, PhD; Malik, Rainer PhD; Dichgans, Martin MD; Mitchell, Braxton D. PhD, MPH +; Kittner, Steven J. MD + and; the Early Onset Stroke Genetics Consortium of the International Stroke Genetics Consortium (ISGC)

doi : 10.1212/WNL.0000000000201006

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Consensus Recommendations for Managing Childhood Cancer Survivors at Risk for Stroke After Cranial Irradiation: A Delphi Study.

Kenney, Lisa B. MD; Ames, Bethany L. MD; Huang, Mary S. MD; Yock, Torunn MD; Bowers, Daniel C. MD; Nekhlyudov, Larissa MD; Williams, David PhD; Hudson, Melissa M. MD; Ullrich, Nicole J. MD, PhD

doi : 10.1212/WNL.0000000000201014

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Adherence to Stroke Care Performance Measures in Different Regions in China, 2015-2019: Evidence From the Chinese Stroke Center Alliance.

Zheng, Suxi *; Zhang, Tong MD, PhD *; Gu, Hong-Qiu PhD; Zhang, Zi-Qin; Yang, Xin MD; Wang, Chunjuan MD, PhD; Li, Hao PhD; Jiang, Yong MD, PhD; Shen, Haipeng PhD +; Li, Zixiao MD, PhD +; Wang, Yongjun MD

doi : 10.1212/WNL.0000000000201024

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Cognitive Impairment in Individuals With Spinal Cord Injury: Findings of a Systematic Review With Robust Variance and Network Meta-analyses.

Sandalic, Danielle MClinPsych; Craig, Ashley PhD; Tran, Yvonne PhD; Arora, Mohit PhD; Pozzato, Ilaria PhD; McBain, Candice PhD; Tonkin, Helen; Simpson, Grahame PhD; Gopinath, Bamini PhD; Kaur, Jasbeer MBBS; Shetty, Sachin MBBS; Weber, Gerard MBBS; Middleton, James PhD

doi : 10.1212/WNL.0000000000200957

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Association of Enlarged Perivascular Spaces With Amyloid Burden and Cognitive Decline in Alzheimer Disease Continuum.

Jeong, Seong Ho MD *; Cha, Jungho PhD *; Park, Mincheol MD; Jung, Jin Ho MD; Ye, Byoung Seok MD, PhD; Sohn, Young H. MD, PhD; Chung, Seok Jong MD **; Lee, Phil Hyu MD, PhD **

doi : 10.1212/WNL.0000000000200989

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Retinal Layer Thinning After Optic Neuritis Is Associated With Future Relapse Remission in Relapsing Multiple Sclerosis.

Bsteh, Gabriel PD, MD, PhD; Krajnc, Nik MD; Riedl, Katharina; Altmann, Patrick MD, PhD; Kornek, Barbara MD; Leutmezer, Fritz MD; Macher, Stefan MD, PhD; Mitsch, Christoph PD, MD, PhD; Pruckner, Philip MD; Rommer, Paulus Stefan MD; Zulehner, Gudrun MD; Pemp, Berthold MD; Berger, Thomas MD, MSc; for the Vienna Multiple Sclerosis Database Study Group

doi : 10.1212/WNL.0000000000200970

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Association of Multiple Sclerosis Prevalence With Sociodemographic, Health Systems, and Lifestyle Factors on a National and Regional Level.

Hwang, Soonmyung BS; Garcia-Dominguez, Maria A. MD; Fitzgerald, Kathryn C. ScD; Saylor, Deanna R. MD, MHS

doi : 10.1212/WNL.0000000000200962

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Refractory Status Epilepticus: Risk Factors and Analysis of Intubation in the Multicenter SENSE Registry.

Beuchat, Isabelle MD; Rosenow, Felix; Kellinghaus, Christoph MD; Trinka, Eugen MD, MSc, FRCP; Unterberger, Iris MD; Ruegg, Stephan MD, FAES; Sutter, Raoul MD; Tilz, Christian MD; Uzelac, Zeljko MD; Rossetti, Andrea O. MD, FAES *; Strzelczyk, Adam MD, MHBA *

doi : 10.1212/WNL.0000000000201099

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Propagation of Diffusion-Weighted MRI Abnormalities in the Preclinical Stage of Sporadic Creutzfeldt-Jakob Disease.

Yasuda, Manato MD; Sugiyama, Atsuhiko MD, PhD; Hokkoku, Hideharu MD; Suichi, Tomoki MD, PhD; Ito, Kimiko MD, PhD; Satoh, Katsuya MD, PhD; Kitamoto, Tetsuyuki MD, PhD; Kuwabara, Satoshi MD, PhD

doi : 10.1212/WNL.0000000000201221

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What Is the Role of Organelle Membrane Contact Sites in Neurodegenerative Diseases?.

Benarroch, Eduardo MD

doi : 10.1212/WNL.0000000000201354

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Proprioceptive Stimuli as a New Type of Trigger for Epilepsy in Stiff Person Syndrome.

Panos Basterra, Paula MD; Nombela, Florentino MD, PhD; Iriarte, Pablo MD; Romero Del Rincon, Celia MD; Alonso Maroto, Jaime MD; Quintas, Sonia MD

doi : 10.1212/WNL.0000000000201196

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Clinical Reasoning: An 80-Year-Old Woman With a Homonymous Hemianopsia.

Tajfirouz, Deena MD; Chen, John J. MD, PhD; Bhatti, M. Tariq MD

doi : 10.1212/WNL.0000000000201175

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Pearls & Oy-sters: Postpipeline Headache Phenomenon: Nummular Headache Presenting After Intracranial Aneurysm Stenting.

Ighodaro, Eseosa T. MD, PhD; Ghislain, Brandon BS; Scharf, Eugene L. MD; Robertson, Carrie E. MD

doi : 10.1212/WNL.0000000000201157

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Right Brain: A Medical Student's Reflections on Creating Space for Dementia Discussions.

Murphy, Kayla Sue BS; Atkinson, David M. MD

doi : 10.1212/WNL.0000000000201121

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Teaching NeuroImage: Lower Limb Muscle Weakness Due to Intramedullary Spinal Cord Lipoma.

Lv, Haijuan MD; Zhao, Hongwei MD; Cai, Yu MD

doi : 10.1212/WNL.0000000000201167

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Editors' Note: Association of Central Hypersomnia and Fatigue in Patients With Multiple Sclerosis: A Polysomnographic Study.

Siegler, James E. MD; Galetta, Steven MD

doi : 10.1212/WNL.0000000000201355

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Reader Response: Association of Central Hypersomnia and Fatigue in Patients With Multiple Sclerosis: A Polysomnographic Study.

Sparasci, Davide; Zecca, Chiara (Lugano, Switzerland); Gobbi, Claudio (Lugano, Switzerland); Manconi, Mauro (Lugano, Switzerland)

doi : 10.1212/WNL.0000000000201356

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Author Response: Association of Central Hypersomnia and Fatigue in Patients With Multiple Sclerosis: A Polysomnographic Study.

Dubessy, Anne-Laure; Stankoff, Bruno; Arnulf, Isabelle

doi : 10.1212/WNL.0000000000201357

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Editors' Note: Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study.

Siegler, James E. MD; Galetta, Steven MD

doi : 10.1212/WNL.0000000000201358

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Reader Response: Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study.

Filippi, Massimo; Cecchetti, Giordano; Spinelli, Edoardo Gioele; Agosta, Federica

doi : 10.1212/WNL.0000000000201359

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Author Response: Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study.

Piazza, Fabrizio; Basso, GianPaolo; Pascarella, Rosario; Carare, Roxana O.; Zedde, Marialuisa

doi : 10.1212/WNL.0000000000201353

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