Journal of the American Society of Nephrology : JASN




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This Month's Highlights

doi : 10.1681/ASN.2021101352

December 2021; Volume 32,Issue 12

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COVID-19 Vaccination in Kidney Transplant Recipients: An Ounce Pre-Transplant is Worth a Pound Post-Transplant

Sindhu Chandran and Peter G. Stock

doi : 10.1681/ASN.2021101347

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Back to the Future: The Role of Metabolic Studies in Therapeutic Advances

Dawn S. Milliner and John C. Lieske

doi : 10.1681/ASN.2021101325

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IgA Nephropathy Needs a Diagnostic Marker of Immunologic Activity to Select the Right Patients for Immunotherapies

Marc Hilhorst and Hans-Joachim Anders

doi : 10.1681/ASN.2021091239

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It Is Time for Patient-Reported Outcome Measures to Be Included in the Approval Process for Solid Organ Transplant Medications

Richard N. Formica and Nicole Turgeon

doi : 10.1681/ASN.2021081136

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Removing Race from Kidney Disease Diagnosis

Susan E. Quaggin and Paul M. Palevsky

doi : 10.1681/ASN.2021091284

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Global Health Education in Nephrology: The Time has Come

Rebecca Ingenhoff, Ursula Brewster, Asghar Rastegar, Robert Kalyesubula and Felix Knauf

doi : 10.1681/ASN.2021060731

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A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease

Cynthia Delgado, Mukta Baweja, Deidra C. Crews, Nwamaka D. Eneanya, Crystal A. Gadegbeku, Lesley A. Inker, Mallika L. Mendu, W. Greg Miller, Marva M. Moxey-Mims, Glenda V. Roberts, Wendy L. St. Peter, Curtis Warfield and Neil R. Powe

doi : 10.1681/ASN.2021070988

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Patient Activation Measure in Dialysis-Dependent Patients in the United States

Daniel Cukor, Leila R. Zelnick, David M. Charytan, Amanda J. Shallcross and Rajnish Mehrotra

doi : 10.1681/ASN.2021030315

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Second Wave Antibodies in Autoimmune Renal Diseases: The Case of Lupus Nephritis

Andrea Angeletti, Maurizio Bruschi, Gabriella Moroni, Renato Alberto Sinico, Franco Franceschini, Micaela Fredi, Augusto Vaglio, Lorenzo Cavagna, Andrea Petretto, Federico Pratesi, Paola Migliorini, Francesco Locatelli, Giulia Pazzola, Giampaola Pesce, Marcello Bagnasco, Angelo Manfredi, Giuseppe A. Ramirez, Pasquale Esposito, Giuseppe Murdaca, Simone Negrini, Leda Cipriani, Barbara Trezzi, Giacomo Emmi, Ilaria Cavazzana, Valentina Binda, Matteo d’Alessandro, Paride Fenaroli, Isabella Pisani, Giacomo Garibotto, Carlomaurizio Montecucco, Domenico Santoro, Francesco Scolari, Stefano Volpi, Marta Mosca, Angela Tincani, Giovanni Candiano, Marco Prunotto, Enrico Verrina, Angelo Ravelli and Gian Marco Ghiggeri

doi : 10.1681/ASN.2021050659

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Use of a Smartphone Camera at the Bedside to Assess Adequacy of Kidney Biopsies

Gurmukteshwar Singh, Mark Massak, Michael Czaplicki, Evan Young, Shree Sharma, Alex Chang, Ashok Bhanushali and Prince Anand

doi : 10.1681/ASN.2021070898

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B and T Cell Responses after a Third Dose of SARS-CoV-2 Vaccine in Kidney Transplant Recipients

Eva Schrezenmeier, Hector Rincon-Arevalo, Ana-Luisa Stefanski, Alexander Potekhin, Henriette Staub-Hohenbleicher, Mira Choi, Friederike Bachmann, Vanessa Proβ, Charlotte Hammett, Hubert Schrezenmeier, Carolin Ludwig, Bernd Jahrsdörfer, Andreia C. Lino, Kai-Uwe Eckardt, Katja Kotsch, Thomas Dörner, Klemens Budde, Arne Sattler and Fabian Halleck

doi : 10.1681/ASN.2021070966

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Generation of Distal Renal Segments Involves a Unique Population of Aqp2+ Progenitor Cells

Chao Gao, Lihe Chen, Enuo Chen, Akaki Tsilosani, Yang Xia and Wenzheng Zhang

doi : 10.1681/ASN.2021030399

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Physiologic Regulation of Systemic Klotho Levels by Renal CaSR Signaling in Response to CaSR Ligands and pHo

Joonho Yoon, Zhenan Liu, Eunyoung Lee, Liping Liu, Silvia Ferre, Johanne Pastor, Jianning Zhang, Orson W. Moe, Audrey N. Chang and R. Tyler Miller

doi : 10.1681/ASN.2021020276

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CHOP-ASO Ameliorates Glomerular and Tubular Damage on Top of ACE Inhibition in Diabetic Kidney Disease

Khurrum Shahzad, Sameen Fatima, Moh’d Mohanad Al-Dabet, Ihsan Gadi, Hamzah Khawaja, Saira Ambreen, Ahmed Elwakiel, Nora Klöting, Matthias Blüher, Peter P. Nawroth, Peter R. Mertens, Sven Michel, Frank Jaschinski, Richard Klar and Berend Isermann

doi : 10.1681/ASN.2021040431

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IL-17 Receptor C Signaling Controls CD4+ TH17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases

Tilman Schmidt, Jonas Luebbe, Christoph Kilian, Jan-Hendrik Riedel, Sonja Hiekmann, Nariaki Asada, Pauline Ginsberg, Lennart Robben, Ning Song, Anna Kaffke, Anett Peters, Alina Borchers, Richard A. Flavell, Nicola Gagliani, Penelope Pelzcar, Samuel Huber, Tobias B. Huber, Jan-Eric Turner, Hans-Joachim Paust, Christian F. Krebs and Ulf Panzer

doi : 10.1681/ASN.2021030426

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Heterozygous Mutation of Vegfr3 Reduces Renal Lymphatics without Renal Dysfunction

Hao Liu, Chitkale Hiremath, Quinten Patterson, Saumya Vora, Zhiguo Shang, Andrew R. Jamieson, Reto Fiolka, Kevin M. Dean, Michael T. Dellinger and Denise K. Marciano

doi : 10.1681/ASN.2021010061

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Detection of PKD1 and PKD2 Somatic Variants in Autosomal Dominant Polycystic Kidney Cyst Epithelial Cells by Whole-Genome Sequencing

Zhengmao Zhang, Hanwen Bai, Jon Blumenfeld, Andrew B. Ramnauth, Irina Barash, Martin Prince, Adrian Y. Tan, Alber Michaeel, Genyan Liu, Ines Chicos, Lior Rennert, Stavros Giannakopoulos, Karen Larbi, Stuart Hughes, Steven P. Salvatore, Brian D. Robinson, Sandip Kapur and Hanna Rennert

doi : 10.1681/ASN.2021050690

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Activation of the Hypoxia-Inducible Factor Pathway Inhibits Epithelial Sodium Channel–Mediated Sodium Transport in Collecting Duct Principal Cells

Eva Dizin, Valérie Olivier, Isabelle Roth, Ali Sassi, Grégoire Arnoux, Suresh Ramakrishnan, Sandrine Morel, Brenda R. Kwak, Johannes Loffing, Edith Hummler, Roland H. Wenger, Ian J. Frew and Eric Feraille

doi : 10.1681/ASN.2021010046

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Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury

Stefan J. Schunk, Juliane Hermann, Tamim Sarakpi, Sarah Triem, Michaela Lellig, Eunsil Hahm, Stephen Zewinger, David Schmit, Ellen Becker, Julia Möllmann, Michael Lehrke, Rafael Kramann, Peter Boor, Peter Lipp, Ulrich Laufs, Winfried März, Jochen Reiser, Joachim Jankowski, Danilo Fliser, Thimoteus Speer and Vera Jankowski

doi : 10.1681/ASN.2021040503

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Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases

Zhi Yu, Jin Jin, Adrienne Tin, Anna Köttgen, Bing Yu, Jingsha Chen, Aditya Surapaneni, Linda Zhou, Christie M. Ballantyne, Ron C. Hoogeveen, Dan E. Arking, Nilanjan Chatterjee, Morgan E. Grams and Josef Coresh

doi : 10.1681/ASN.2020111599

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Endogenous Oxalate Production in Primary Hyperoxaluria Type 1 Patients

Sander F. Garrelfs, Dewi van Harskamp, Hessel Peters-Sengers, Chris H.P. van den Akker, Ronald J.A. Wanders, Frits A. Wijburg, Johannes B. van Goudoever, Jaap W. Groothoff, Henk Schierbeek and Michiel J.S. Oosterveld

doi : 10.1681/ASN.2021060729

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Intensity of Macrophage Infiltration in Glomeruli Predicts Response to Immunosuppressive Therapy in Patients with IgA Nephropathy

Di Xie, Hao Zhao, Xin Xu, Zhanmei Zhou, Cailing Su, Nan Jia, Youhua Liu and Fan Fan Hou

doi : 10.1681/ASN.2021060815

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Effect of Low-Dose Methotrexate on eGFR and Kidney Adverse Events: A Randomized Clinical Trial

Jeffrey A. Sparks, Kathleen M. M. Vanni, Matthew A. Sparks, Chang Xu, Leah M. Santacroce, Robert J. Glynn, Paul M. Ridker and Daniel H. Solomon

doi : 10.1681/ASN.2021050598

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Predictors and Dynamics of the Humoral and Cellular Immune Response to SARS-CoV-2 mRNA Vaccines in Hemodialysis Patients: A Multicenter Observational Study

Jens Van Praet, Marijke Reynders, Dirk De Bacquer, Liesbeth Viaene, Melanie K. Schoutteten, Rogier Caluwé, Peter Doubel, Line Heylen, Annelies V. De Bel, Bruno Van Vlem, Deborah Steensels and An S. De Vriese

doi : 10.1681/ASN.2021070908

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Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection

Paolo Cravedi, Patrick Ahearn, Lin Wang, Tanuja Yalamarti, Susan Hartzell, Yorg Azzi, Madhav C. Menon, Aditya Jain, Marzuq Billah, Marcelo Fernandez-Vina, Howard M. Gebel, E. Steve Woodle, Natalie S. Haddad, Andrea Morrison-Porter, F. Eun-Hyung Lee, Ignacio Sanz, Enver Akalin, Alin Girnita and Jonathan S. Maltzman

doi : 10.1681/ASN.2021040573

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CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients

Baptiste Lamarthée, Carole Burger, Charlotte Leclaire, Emilie Lebraud, Aniela Zablocki, Lise Morin, Xavier Lebreton, Béatrice Charreau, Renaud Snanoudj, Soëli Charbonnier, Tifanie Blein, Mélanie Hardy, Julien Zuber, Simon Satchell, Morgan Gallazzini, Fabiola Terzi, Christophe Legendre, Jean Luc Taupin, Marion Rabant, Claire Tinel and Dany Anglicheau

doi : 10.1681/ASN.2021050689

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Conversion from Calcineurin Inhibitor– to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial

Klemens Budde, Rohini Prashar, Hermann Haller, Maria C. Rial, Nassim Kamar, Avinash Agarwal, Johan W. de Fijter, Lionel Rostaing, Stefan P. Berger, Arjang Djamali, Nicolae Leca, Lisa Allamassey, Sheng Gao, Martin Polinsky and Flavio Vincenti

doi : 10.1681/ASN.2021050628

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