Annals of Oncology




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Table of Contents

doi : 10.1016/S0923-7534(21)02190-6

Volume 32, Issue 9, September 2021, Pages i-ii

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Genome instability and success of checkpoint inhibitors: form and levels matter

S.Derks12

doi : 10.1016/j.annonc.2021.06.022

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Co-targeting the VEGF axis and immune checkpoints in NSCLC: back to the future

S.P.L.SawD.S.W.Tan

doi : 10.1016/j.annonc.2021.06.026

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Gene expression signatures for tailoring adjuvant chemotherapy of luminal breast cancer: stronger evidence, greater trust

M.J.Piccart12K.Kalinsky3R.Gray4W.E.Barlow5C.Poncet6F.Cardoso7E.Winer8J.Sparano9

doi : 10.1016/j.annonc.2021.05.804

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Right to Try, expanded access use, Project Facilitate, and clinical trial reform

N.K.Reddy1V.Subbiah234

doi : 10.1016/j.annonc.2021.06.016

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Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

S.Rao1M.G.Guren2K.Khan34G.Brown5A.G.Renehan6S.E.Steigen7E.Deutsch8E.Martinelli9D.Arnold10ESMO Guidelines Committee

doi : 10.1016/j.annonc.2021.06.015

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Targeting KRAS in non-small-cell lung cancer: recent progress and new approaches

M.Reck1D.P.Carbone2M.Garassino3F.Barlesi45

doi : 10.1016/j.annonc.2021.06.001

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Practical considerations in screening for genetic alterations in cholangiocarcinoma

T.S.Bekaii-Saab1J.Bridgewater2N.Normanno3

doi : 10.1016/j.annonc.2021.04.012

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Molecular determinants of clinical outcomes with pembrolizumab versus paclitaxel in a randomized, open-label, phase III trial in patients with gastroesophageal adenocarcinoma

K.Shitara1M.Özgüroğlu2Y.-J.Bang3M.Di Bartolomeo4M.Mandalà5M.-H.Ryu6C.Caglevic7H.C.Chung8K.Muro9E.Van Cutsem10J.Kobie11R.Cristescu11D.Aurora-Garg11J.Lu11C.-S.Shih11D.Adelberg11Z.A.Cao11C.S.Fuchs12

doi : 10.1016/j.annonc.2021.05.803

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Nivolumab with carboplatin, paclitaxel, and bevacizumab for first-line treatment of advanced nonsquamous non-small-cell lung cancer

S.Sugawara1†J.-S.Lee2†J.-H.Kang3H.R.Kim4N.Inui5T.Hida6K.H.Lee7T.Yoshida8H.Tanaka9C.-T.Yang10M.Nishio11Y.Ohe8T.Tamura12N.Yamamoto13C.-J.Yu14H.Akamatsu13Y.Namba15N.Sumiyoshi16K.Nakagawa17

doi : 10.1016/j.annonc.2021.06.004

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Biomarker analyses in the phase III ASCENT study of sacituzumab govitecan versus chemotherapy in patients with metastatic triple-negative breast cancer

A.Bardia1S.M.Tolaney2K.Punie3D.Loirat4M.Oliveira5K.Kalinsky67A.Zelnak8P.Aftimos9F.Dalenc10S.Sardesai11E.Hamilton12P.Sharma13S.Recalde14E.C.Gil15T.Traina16J.O’Shaughnessy17J.Cortes18M.Tsai19…S.A.Hurvitz27

doi : 10.1016/j.annonc.2021.06.002

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Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial

A.A.Hamid12H.-C.Huang3V.Wang4Y.-H.Chen4F.Feng5R.Den6G.Attard7E.M.Van Allen1P.T.Tran8D.E.Spratt9R.Dittamore3E.Davicioni3G.Liu10R.DiPaola11M.A.Carducci8C.J.Sweeney1

doi : 10.1016/j.annonc.2021.06.003

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Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set

E.A.Klein1D.Richards2A.Cohn3M.Tummala4R.Lapham5D.Cosgrove6G.Chung7J.Clement8J.Gao9N.Hunkapiller9A.Jamshidi9K.N.Kurtzman9M.V.Seiden10C.Swanton1112M.C.Liu13

doi : 10.1016/j.annonc.2021.05.806

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Deep learning for diagnosis and survival prediction in soft tissue sarcoma

S.Foersch1M.Eckstein2D.-C.Wagner1F.Gach1A.-C.Woerl13J.Geiger13C.Glasner13S.Schelbert1S.Schulz1S.Porubsky1A.Kreft1A.Hartmann2A.Agaimy2W.Roth1

doi : 10.1016/j.annonc.2021.06.007

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TMB cut-offs fail to predict benefit of PD-1 blockade in gastroesophageal adenocarcinoma in KEYNOTE-061

M.B.FooteS.B.MaronA.CercekG.ArgilésB.RousseauL.A.DiazJr.

doi : 10.1016/j.annonc.2021.06.006

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Adjuvant nivolumab for the management of pathological residual disease in esophageal or junctional tumors: a word of caution

P.K.Garg1R.Kumar2P.Dixit3

doi : 10.1016/j.annonc.2021.04.024

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Reply to the letter to the editor: adjuvant nivolumab for the management of the pathological residual disease in esophageal or junctional tumors: a word of caution by P.K. Garg, R. Kumar and P. Dixit

E.C.Smyth1†V.Gambardella23†A.Cervantes23‡T.Fleitas23‡

doi : 10.1016/j.annonc.2021.05.795

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Association between HER2 status in residual disease and sensitivity to trastuzumab emtansine

K.Altundag

doi : 10.1016/j.annonc.2021.05.794

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Characteristics of residual invasive breast cancer after neoadjuvant therapy in the KATHERINE study

E.P.Mamounas

doi : 10.1016/j.annonc.2021.05.802

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Use of clinical selection for intensification of therapy in metastatic castrate-resistant prostate cancer

R.Iacovelli1C.Ciccarese12G.Tortora12

doi : 10.1016/j.annonc.2021.06.005

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Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab

D.Fabrizio1R.Cristescu2L.Albacker1A.Snyder2A.Ward1J.Lunceford2D.Aurora-Garg2F.Jin2J.Hopkins1E.Rubin2P.Hegde1

doi : 10.1016/j.annonc.2021.05.805

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Reply to: ‘Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.’ by D. Fabrizio et al.

D.J.McGrail1P.G.Pilié2N.U.Rashid34L.Voorwerk5M.Slagter678M.Kok59E.Jonasch2M.Khasraw10A.B.Heimberger1112N.T.Ueno13R.Ferrarotto14J.T.Chang1516S.-Y.Lin1

doi : 10.1016/j.annonc.2021.06.017

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VP7-2021: KEYNOTE-522: Phase III study of neoadjuvant pembrolizumab + chemotherapy vs. placebo + chemotherapy, followed by adjuvant pembrolizumab vs. placebo for early-stage TNBC

P.Schmid1J.Cortes2R.Dent3L.Pusztai4H.McArthur5S.Kümmel6J.Bergh7C.Denkert8Y.H.Park9R.Hui10N.Harbeck11M.Takahashi12M.Untch13P.A.Fasching14F.Cardoso15Y.Ding16K.Tryfonidis17G.Aktan17…J.O’Shaughnessy18

doi : 10.1016/j.annonc.2021.06.014

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Corrigendum to ‘Measures of body fatness and height in early and mid-to-late adulthood and prostate cancer: risk and mortality in The Pooling Project of Prospective Studies of Diet and Cancer’: [Annals of Oncology Volume 31, Issue 1, January 2020, Pages 103-114]

J.M.Genkinger12K.Wu3M.Wang456D.Albanes7A.Black7P.A.van den Brandt8K.A.Burke1M.B.Cook7S.M.Gapstur9G.G.Giles1011E.Giovannucci346G.G.Goodman12P.J.Goodman13N.Håkansson14T.J.Key15S.Männistö16L.Le Marchand17L.M.Liao7…S.A.Smith-Warner34

doi : 10.1016/j.annonc.2021.07.001

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