Journal of Clinical Oncology




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Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Induction or Consolidation Chemotherapy?.

Aref, Amr MD 1,2,; Abdalla, Ahmed MD 3

doi : 10.1200/JCO.22.00506

Volume 40(23) pgs. 2515-2658 August 10, 2022

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Testing Endocrine Response for Managing Primary Estrogen Receptor-Positive Breast Cancer.

Dowsett, Mitch PhD 1,,

doi : 10.1200/JCO.22.00214

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Current Gaps in Fertility Preservation for Men: How Can We do Better?.

Ghidei, Luwam MD 1,; Sullivan, John MD 2; Valero Carrion, Rair Jose MD 2; Schammel, Joshua MD 2; Lipshultz, Larry MD 2,; McKenzie, Laurie J. MD 1,3

doi : 10.1200/JCO.21.02714

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1).

Ou, Sai-Hong Ignatius MD, PhD 1,,; Janne, Pasi A. MD, PhD 2,; Leal, Ticiana A. MD 3,; Rybkin, Igor I. MD, PhD 4,; Sabari, Joshua K. MD, PhD 5,; Barve, Minal A. MD 6,; Bazhenova, Lyudmila MD 7,; Johnson, Melissa L. MD 8,; Velastegui, Karen L. BSc 9,; Cilliers, Cornelius PhD 9,; Christensen, James G. PhD 9,; Yan, Xiaohong PhD 9,; Chao, Richard C. MD 9,; Papadopoulos, Kyriakos P. MD 10,

doi : 10.1200/JCO.21.02752

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Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors.

Lassman, Andrew B. MD 1,2,3,; Hoang-Xuan, Khe MD 4,; Polley, Mei-Yin C. PhD 5; Brandes, Alba A. MD 6; Cairncross, J. Gregory MD 7,; Kros, Johan M. MD 8; Ashby, Lynn S. MD 9,; Taphoorn, Martin J.B. MD 10,11; Souhami, Luis MD 12,; Dinjens, Winand N.M. PhD 8,; Laack, Nadia N. MD 13,; Kouwenhoven, Mathilde C.M. MD 14; Fink, Karen L. MD, PhD 15,; French, Pim J. MD 16,; Macdonald, David R. MD 17,; Lacombe, Denis MD 18; Won, Minhee MA 5; Gorlia, Thierry PhD 18; Mehta, Minesh P. MD 19,; van den Bent, Martin J. MD 16,,

doi : 10.1200/JCO.21.02543

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Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy.

Garcia-Aguilar, Julio MD, PhD 1,,; Patil, Sujata PhD 2,; Gollub, Marc J. MD 3,; Kim, Jin K. MD 1; Yuval, Jonathan B. MD 1; Thompson, Hannah M. MD 1; Verheij, Floris S. MD 1; Omer, Dana M. MD 1; Lee, Meghan BS 1,; Dunne, Richard F. MD 4,; Marcet, Jorge MD 5,; Cataldo, Peter MD 6; Polite, Blase MD 7,; Herzig, Daniel O. MD 8; Liska, David MD 9,; Oommen, Samuel MD 10; Friel, Charles M. MD 11; Ternent, Charles MD 12,; Coveler, Andrew L. MD 13,; Hunt, Steven MD 14; Gregory, Anita MD 15; Varma, Madhulika G. MD 16; Bello, Brian L. MD 17; Carmichael, Joseph C. MD 18,; Krauss, John MD 19,; Gleisner, Ana MD 20; Paty, Philip B. MD 1; Weiser, Martin R. MD 1,; Nash, Garrett M. MD 1,; Pappou, Emmanouil MD 1,; Guillem, Jose G. MD 21,; Temple, Larissa MD 22; Wei, Iris H. MD 1; Widmar, Maria MD 1,; Lin, Sabrina MS 2; Segal, Neil H. MD, PhD 23,; Cercek, Andrea MD 23,; Yaeger, Rona MD 23,; Smith, J. Joshua MD, PhD 1,; Goodman, Karyn A. MD 24,; Wu, Abraham J. MD 25,; Saltz, Leonard B. MD 23,

doi : 10.1200/JCO.22.00032

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Endocrine Therapy Response and 21-Gene Expression Assay for Therapy Guidance in HR+/HER2- Early Breast Cancer.

Nitz, Ulrike A. MD 1,2,; Gluz, Oleg MD 1,2,3,; Kummel, Sherko MD 1,4,5,; Christgen, Matthias MD, PhD 6; Braun, Michael MD 7,; Aktas, Bahriye MD 8,9,; Ludtke-Heckenkamp, Kerstin MD 10,; Forstbauer, Helmut MD 11,; Grischke, Eva-Maria MD 12; Schumacher, Claudia MD 13; Darsow, Maren MD 14,; Krauss, Katja MD 15; Nuding, Benno MD 16,; Thill, Marc MD 17,; Potenberg, Jochem MD 18; Uleer, Christoph MD 19,; Warm, Mathias MD 20; Fischer, Hans Holger MD 21,; Malter, Wolfram MD 3,; Hauptmann, Michael PhD 22,23; Kates, Ronald E. PhD 1,; Graser, Monika MD 1,2,24; Wurstlein, Rachel MD 25,; Shak, Steven MD 26,; Baehner, Frederick MD 26,; Kreipe, Hans H. MD 6,; Harbeck, Nadia MD, PhD 1,25,,; for the West German Study Group

doi : 10.1200/JCO.21.02759

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Phase Ib Study of Navicixizumab Plus Paclitaxel in Patients With Platinum-Resistant Ovarian, Primary Peritoneal, or Fallopian Tube Cancer.

Fu, Siqing MD, PhD 1,; Corr, Bradley R. MD 2,; Culm-Merdek, Kerry PhD 3,; Mockbee, Colleen MBA 3,; Youssoufian, Hagop MD 3,; Stagg, Robert PharmD 4,; Naumann, R. Wendel MD 5,; Wenham, Robert M. MD 6,; Rosengarten, Rafael D. PhD 7,; Benjamin, Laura PhD 3,; Hamilton, Erika Paige MD 8,9,; Moore, Kathleen N. MD 8,10,,

doi : 10.1200/JCO.21.01801

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Pre-existing Thyroid Autoimmunity and Risk of Papillary Thyroid Cancer: A Nested Case-Control Study of US Active-Duty Personnel.

McLeod, Donald S.A. MBBS, PhD 1,2,; Bedno, Sheryl A. MD 3,4; Cooper, David S. MD 5,; Hutfless, Susan M. PhD 6,; Ippolito, Silvia MD 7; Jordan, Susan J. MBBS, PhD 8; Matos, Peter G. DO 9; Neale, Rachel E. PhD 1,8,; Sabini, Elena MD 10; Whiteman, David C. MBBS, PhD 1,; Ladenson, Paul W. MD 5,; Caturegli, Patrizio MD 10

doi : 10.1200/JCO.21.02618

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Mortality and Second Cancer Incidence After Treatment for Testicular Cancer: Psychosocial Health and Lifestyle Are Modifiable Prognostic Factors.

Fossa, Sophie D. PhD 1,2,; Dahl, Alv A. PhD 1; Thorsen, Lene PhD 3; Hellesnes, Ragnhild PhD 4; Kiserud, Cecilie E. PhD 1; Tandstad, Torgrim PhD 5,6; Brydoy, Marianne PhD 7; Haugnes, Hege S. PhD 4,8; Myklebust, Tor A. PhD 9,10

doi : 10.1200/JCO.21.02105

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Waldenstrom Macroglobulinemia: Tailoring Therapy for the Individual.

Gertz, Morie A. MD, MACP 1,,

doi : 10.1200/JCO.22.00495

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Expanding the Arsenal of Clinically Active KRAS G12C Inhibitors.

Arbour, Kathryn C. MD 1,2,; Lito, Piro MD, PhD 1,2,3,,

doi : 10.1200/JCO.22.00562

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Systemic Therapy for Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: ASCO Guideline Update.

Giordano, Sharon H. MD, MPH 1,; Franzoi, Maria Alice B. MD 2; Temin, Sarah MSPH 3; Anders, Carey K. MD 4,; Chandarlapaty, Sarat MD, PhD 5,; Crews, Jennie R. MD 6; Kirshner, Jeffrey J. MD 7; Krop, Ian E. MD, PhD 8,; Lin, Nancy U. MD 8,; Morikawa, Aki MD, PhD 9,; Patt, Debra A. MD, MPH, MBA 10,; Perlmutter, Jane PhD 11; Ramakrishna, Naren MD, PhD 12,; Davidson, Nancy E. MD 13

doi : 10.1200/JCO.22.00519

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Management of Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Guideline Update.

Ramakrishna, Naren MD, PhD 1,; Anders, Carey K. MD 2,; Lin, Nancy U. MD 3,; Morikawa, Aki MD, PhD 4,; Temin, Sarah MSPH 5; Chandarlapaty, Sarat MD, PhD 6,; Crews, Jennie R. MD 7; Davidson, Nancy E. MD 8; Franzoi, Maria Alice B. MD 9; Kirshner, Jeffrey J. MD 10; Krop, Ian E. MD, PhD 3,; Patt, Debra A. MD, MPH, MBA 11,; Perlmutter, Jane PhD 12; Giordano, Sharon H. MD, MPH 13,

doi : 10.1200/JCO.22.00520

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Neoadjuvant Programmed Cell Death Protein 1 and Chemotherapy in Combination in Muscle-Invasive Urothelial Cancer: Promising, But Not Deserving to Try Further.

Zhang, Sheng MD

doi : 10.1200/JCO.22.00420

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Reply to S. Zhang.

Lattanzi, Michael MD; Funt, Samuel A. MD; Rosenberg, Jonathan E. MD

doi : 10.1200/JCO.22.00809

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