Journal of Clinical Oncology




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Checkpoint Blockade: Not Yet NINJA Status in Ovarian Cancer.

Porter, Rebecca L. MD, PhD 1; Matulonis, Ursula A. MD 1,,

doi : 10.1200/JCO.21.01886

Volume 39(33) pgs. 3651-3765 November 20, 2021

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Treatment Holidays for Patients With Metastatic Colorectal Cancer.

Kasi, Pashtoon Murtaza MD, MS 1,,

doi : 10.1200/JCO.21.01999

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nab-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors.

Wagner, Andrew J. MD, PhD 1,,; Ravi, Vinod MD 2,; Riedel, Richard F. MD 3,; Ganjoo, Kristen MD 4,; Van Tine, Brian A. MD, PhD 5,; Chugh, Rashmi MD 6,; Cranmer, Lee MD, PhD 7,; Gordon, Erlinda M. MD 8,; Hornick, Jason L. MD, PhD 9,; Du, Heng MD 9; Grigorian, Berta BS 10,; Schmid, Anita N. PhD 10,; Hou, Shihe PhD 10,; Harris, Katherine DrPH 10,; Kwiatkowski, David J. MD, PhD 9,; Desai, Neil P. PhD 10,; Dickson, Mark A. MD 11,

doi : 10.1200/JCO.21.01728

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Nivolumab Versus Gemcitabine or Pegylated Liposomal Doxorubicin for Patients With Platinum-Resistant Ovarian Cancer: Open-Label, Randomized Trial in Japan (NINJA).

Hamanishi, Junzo MD, PhD 1,,; Takeshima, Nobuhiro MD, PhD 2,3; Katsumata, Noriyuki MD 4,; Ushijima, Kimio MD, PhD 5,; Kimura, Tadashi MD, PhD 6,; Takeuchi, Satoshi MD, PhD 7,8; Matsumoto, Koji MD 9,; Ito, Kimihiko MD, PhD 10,; Mandai, Masaki MD, PhD 11,12; Nakai, Hidekatsu MD, PhD 11; Sakuragi, Noriaki MD, PhD 13,14; Watari, Hidemichi MD, PhD 13,; Takahashi, Nobutaka MD, PhD 15,; Kato, Hidenori MD, PhD 16; Hasegawa, Kosei MD, PhD 17,; Yonemori, Kan MD, PhD 18,; Mizuno, Mika MD, PhD 19,20; Takehara, Kazuhiro MD, PhD 21,; Niikura, Hitoshi MD, PhD 22,23,; Sawasaki, Takashi MD, PhD 24,25; Nakao, Sari MD, PhD 26,; Saito, Toshiaki MD, PhD 27,; Enomoto, Takayuki MD, PhD 28,; Nagase, Satoru MD, PhD 29,; Suzuki, Nao MD, PhD 30; Matsumoto, Takashi MD, PhD 31; Kondo, Eiji MD, PhD 32; Sonoda, Kenzo MD, PhD 33,34; Aihara, Satomi MD, PhD 35,36; Aoki, Yoichi MD, PhD 37; Okamoto, Aikou MD, PhD 38,; Takano, Hirokuni MD, PhD 39; Kobayashi, Hiroshi MD, PhD 40,41; Kato, Hisamori MD, PhD 42; Terai, Yoshito MD, PhD 43,44,; Takazawa, Akira PhD 45,; Takahashi, Yusuke MSc 46,; Namba, Yoshinobu MD 47,; Aoki, Daisuke MD, PhD 48,; Fujiwara, Keiichi MD, PhD 17,; Sugiyama, Toru MD, PhD 7,49; Konishi, Ikuo MD, PhD 50

doi : 10.1200/JCO.21.00334

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Late Toxicity After Adjuvant Conventional Radiation Versus Image-Guided Intensity-Modulated Radiotherapy for Cervical Cancer (PARCER): A Randomized Controlled Trial.

Chopra, Supriya MD, DNB 1,,; Gupta, Sudeep DM 2,; Kannan, Sadhana MSc 3; Dora, Tapas MD 4; Engineer, Reena DNB 5; Mangaj, Akshay MD 5; Maheshwari, Amita MD 6; Shylasree, T. Surappa MD 6; Ghosh, Jaya MD, DM 2; Paul, Siji N. MSc 1; Phurailatpam, Reena MSc 1; Charnalia, Mayuri MSc 1; Alone, Mitali BSc 7; Swamidas, Jamema PhD 1; Mahantshetty, Umesh MD 5,; Deodhar, Kedar MD 8,; Kerkar, Rajendra MD 6; Shrivastava, Shyam K. MD, DNB 5

doi : 10.1200/JCO.20.02530

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Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial.

Adams, Richard A. MD 1,; Fisher, David J. MSc 2; Graham, Janet MD 3,; Seligmann, Jenny F. PhD 4,; Seymour, Matthew PhD 4,; Kaplan, Richard MD, PhD 2,; Yates, Emma MSc 2; Parmar, Mahesh PhD 2,; Richman, Susan D. PhD 4; Quirke, Philip PhD 4,; Butler, Rachel PhD 5,; Brown, Ewan MD 6,; Collinson, Fiona MD 4,; Falk, Stephen MD 7,; Wasan, Harpreet PhD 8,; Shiu, Kai-Keen PhD 9,; Middleton, Gary PhD 10,; Samuel, Leslie MD 11,; Wilson, Richard H. PhD 3,; Brown, Louise C. PhD 2,,; Maughan, Timothy S. MD 12,; on behalf of the FOCUS4 Trial Investigators

doi : 10.1200/JCO.21.01436

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Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring.

Seligmann, Jenny F. MD 1,; Fisher, David J. MSc 2; Brown, Louise C. PhD 2,,; Adams, Richard A. MD, MBBS 3,; Graham, Janet PhD, MBChB 4,; Quirke, Philip PhD 1,; Richman, Susan D. PhD 1; Butler, Rachel PhD 5,; Domingo, Enric PhD 6; Blake, Andrew MSc 6; Yates, Emma MSc 2; Braun, Michael PhD, MBChB 7,; Collinson, Fiona MD 1,; Jones, Rob PhD 8,; Brown, Ewan PhD 9,; de Winton, Emma MBBS 10; Humphrey, Timothy C. DPhil 6,; Parmar, Mahesh PhD 2,; Kaplan, Richard MD, PhD 2,; Wilson, Richard H. PhD 4,; Seymour, Matthew MD 1,; Maughan, Timothy S. MD 6,,; on behalf of the FOCUS4 Trial Investigators

doi : 10.1200/JCO.21.01435

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Dose-Adjusted Etoposide, Doxorubicin, and Cyclophosphamide With Vincristine and Prednisone Plus Rituximab Therapy in Children and Adolescents With Primary Mediastinal B-Cell Lymphoma: A Multicenter Phase II Trial.

Burke, G. A. Amos MB ChB, PhD 1,,; Minard-Colin, Veronique MD, PhD 2,; Auperin, Anne MD, PhD 3,; Alexander, Sarah MD 4; Pillon, Marta MD, PhD 5; Delgado, Rafael MD, PhD 6; Zsiros, Jozsef MD, PhD 7; Uyttebroeck, Anne MD, PhD 8; Dartigues, Peggy MD 9; Miles, Rodney R. MD, PhD 10; Kazanowska, Bernarda MD, PhD 11; Chiang, Alan K. MD, PhD 12; Haouy, Stephanie MD 13; Bollard, Catherine M. MB ChB, MD 14,; Csoka, Monika MD, PhD 15; Wheatley, Keith PhD 16,; Barkauskas, Donald A. PhD 17,; Adamson, Peter C. MD 18,; Vassal, Gilles MD, PhD 19,; Patte, Catherine MD 2; Gross, Thomas G. MD, PhD 20

doi : 10.1200/JCO.21.00920

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Cabozantinib in Combination With Atezolizumab for Advanced Renal Cell Carcinoma: Results From the COSMIC-021 Study.

Pal, Sumanta K. MD 1,,; McGregor, Bradley MD 2,; Suarez, Cristina MD 3,; Tsao, Che-Kai MD 4,; Kelly, William DO 5,; Vaishampayan, Ulka MD 6,7,; Pagliaro, Lance MD 8,; Maughan, Benjamin L. MD 9,; Loriot, Yohann MD 10,; Castellano, Daniel MD 11,; Srinivas, Sandy MD 12,; McKay, Rana R. MD 13,; Dreicer, Robert MD 14,; Hutson, Thomas DO 15,; Dubey, Sarita MD 16,; Werneke, Scott PhD 17,; Panneerselvam, Ashok PhD 17,; Curran, Dominic MBChB 17,; Scheffold, Christian MD 17,; Choueiri, Toni K. MD 2,; Agarwal, Neeraj MD 9,

doi : 10.1200/JCO.21.00939

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Personalized Prediction Model to Risk Stratify Patients With Myelodysplastic Syndromes.

Nazha, Aziz MD 1,2,,; Komrokji, Rami MD 3,; Meggendorfer, Manja PhD 4,; Jia, Xuefei MS 5; Radakovich, Nathan MS 6; Shreve, Jacob MD 1; Hilton, C. Beau BS 6; Nagata, Yasunubo MD 7; Hamilton, Betty K. MD 1,; Mukherjee, Sudipto MD 1,; Al Ali, Najla MS 3; Walter, Wencke PhD 4,; Hutter, Stephan PhD 4,; Padron, Eric MD 3,; Sallman, David MD 3,; Kuzmanovic, Teodora MS 7; Kerr, Cassandra MS 7; Adema, Vera PhD 7; Steensma, David P. MD 8,; Dezern, Amy MD 9,; Roboz, Gail MD 10,; Garcia-Manero, Guillermo MD 11,; Erba, Harry MD 12,; Haferlach, Claudia MD 4,; Maciejewski, Jaroslaw P. MD 7,; Haferlach, Torsten MD 4,; Sekeres, Mikkael A. MD 13,

doi : 10.1200/JCO.20.02810

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Genomic Profiling of Lung Adenocarcinoma in Never-Smokers.

Devarakonda, Siddhartha MD 1,2; Li, Yize MS 1,3,4; Martins Rodrigues, Fernanda MS 1,3,4; Sankararaman, Sumithra PhD 1; Kadara, Humam PhD 5,; Goparaju, Chandra PhD 6; Lanc, Irena PhD 7,; Pepin, Kymberlie BS 1; Waqar, Saiama N. MBBS, MD 1,2,; Morgensztern, Daniel MD 1,2,; Ward, Jeffrey MD, PhD 1,2,; Masood, Ashiq MD 8,; Fulton, Robert MS 3; Fulton, Lucinda MS 3; Gillette, Michael A. MD, PhD 9; Satpathy, Shankha PhD 9,; Carr, Steven A. PhD 9,; Wistuba, Ignacio MS 5,; Pass, Harvey MD 6,; Wilson, Richard K. PhD 10; Ding, Li PhD 1,2,3,11,12; Govindan, Ramaswamy MD 1,2,,

doi : 10.1200/JCO.21.01691

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On the Absence of Sound.

Chow, Ryan D. BA 1,,

doi : 10.1200/JCO.21.01833

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Decision Making in Geriatric Oncology: Supported Versus Assisted Decision Making.

Sommerlatte, Sabine Mmel; Schmidt, Heike MD; Vordermark, Dirk MD; Schildmann, Jan MD, MA

doi : 10.1200/JCO.21.01643

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Reply to S. Sommerlatte et al.

DuMontier, Clark MD, MPH; Loh, Kah Poh MBBCh, BAO, MS; Soto-Perez-de-Celis, Enrique MD; Dale, William MD, PhD

doi : 10.1200/JCO.21.01865

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May Different Treatment Volumes and Technical Approaches Have an Impact on Second Malignancies Risk?.

Francolini, Giulio MD; Ciccone, Lucia Pia MD; Di Cataldo, Vanessa MD; Detti, Beatrice MD; Simontacchi, Gabriele MD; Loi, Mauro MD; Mangoni, Monica MD; Desideri, Isacco MD; Meattini, Icro MD; Livi, Lorenzo MD

doi : 10.1200/JCO.21.01790

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Reply to G. Francolini et al.

D'Amico, Anthony V. MD, PhD; Xie, Wanling MS; Kantoff, Philip W. MD

doi : 10.1200/JCO.21.01977

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