Journal of Clinical Oncology




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Remembering Emil J. Freireich: A Portrait of Courage and Innovation in Cancer Research-March 16, 1927 to February 1, 2021.

Estey, Elihu MD 1; Talpaz, Moshe MD 2,; Kantarjian, Hagop MD 3,,

doi : 10.1200/JCO.21.00493

Volume 39(27) pgs. 2973-3092 September 20, 2021

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Reasonable Attempt at a Randomized Trial in Relapsed Rhabdomyosarcoma.

Gupta, Abha A. MD, MSc 1,

doi : 10.1200/JCO.21.01631

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Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft Tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.

Defachelles, Anne-Sophie MD 1,; Bogart, Emilie MSc 1; Casanova, Michela MD 2,; Merks, Johannes H. M. MD 3,; Bisogno, Gianni MD, PhD 4,; Calareso, Giuseppina MD 2; Gallego Melcon, Soledad MD, PhD 5,; Gatz, Susanne Andrea MD 6,; Le Deley, Marie-Cecile MD 1; McHugh, Kieran MD 7; Probst, Alicia MSc 1; Rocourt, Nathalie MD 1; van Rijn, Rick R. MD, PhD 8,; Wheatley, Keith PhD 9,; Minard-Colin, Veronique MD, PhD 10,; Chisholm, Julia C. MD 11,

doi : 10.1200/JCO.21.00124

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Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study.

Kelley, Robin Kate MD 1,,; Sangro, Bruno MD, PhD 2,; Harris, William MD 3,; Ikeda, Masafumi MD, PhD 4,; Okusaka, Takuji MD, PhD 5,; Kang, Yoon-Koo MD, PhD 6,; Qin, Shukui MD, PhD 7; Tai, David W.-M. MD 8,; Lim, Ho Yeong MD 9,; Yau, Thomas MD 10,; Yong, Wei-Peng MD 11,; Cheng, Ann-Lii MD, PhD 12,; Gasbarrini, Antonio MD 13,; Damian, Silvia MD 14,; Bruix, Jordi MD 15,; Borad, Mitesh MD 16,; Bendell, Johanna MD 17,; Kim, Tae-You MD 18; Standifer, Nathan PhD 19,; He, Philip PhD 20,; Makowsky, Mallory PharmD 20,; Negro, Alejandra PhD 20,; Kudo, Masatoshi MD, PhD 21,; Abou-Alfa, Ghassan K. MD, MBA 22,23,

doi : 10.1200/JCO.20.03555

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Donafenib Versus Sorafenib in First-Line Treatment of Unresectable or Metastatic Hepatocellular Carcinoma: A Randomized, Open-Label, Parallel-Controlled Phase II-III Trial.

Qin, Shukui MD 1; Bi, Feng MD 2,; Gu, Shanzhi MD 3; Bai, Yuxian MD 4; Chen, Zhendong MD 5; Wang, Zishu MD 6; Ying, Jieer MD 7; Lu, Yinying MD 8; Meng, Zhiqiang MD 9; Pan, Hongming MD 10; Yang, Ping MD 11; Zhang, Helong MD 12; Chen, Xi MD 13; Xu, Aibing MD 14; Cui, Chengxu BA 15; Zhu, Bo MD 16; Wu, Jian MD 17; Xin, Xiaoli MD 18; Wang, Jufeng MD 19; Shan, Jinlu MD 20; Chen, Junhui BA 21; Zheng, Zhendong MD 22; Xu, Li MD 23; Wen, Xiaoyu MD 24; You, Zhenyu MD 25; Ren, Zhenggang MD 26,; Liu, Xiufeng MD 1; Qiu, Meng MD 2; Wu, Liqing MD 27; Chen, Feng PhD 28

doi : 10.1200/JCO.21.00163

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Development and Validation of a Breast Cancer Risk Prediction Model for Childhood Cancer Survivors Treated With Chest Radiation: A Report From the Childhood Cancer Survivor Study and the Dutch Hodgkin Late Effects and LATER Cohorts.

Moskowitz, Chaya S. PhD 1,; Ronckers, Cecile M. PhD 2,3; Chou, Joanne F. MS 1; Smith, Susan A. MPH 4; Friedman, Danielle Novetsky MD 1,; Barnea, Dana MD 5; Kok, Judith L. PhD 2; de Vries, Simone PhD 6; Wolden, Suzanne L. MD 1; Henderson, Tara O. MD 7,; van der Pal, Helena J. H. MD, PhD 2; Kremer, Leontien C. M. MD, PhD 2; Neglia, Joseph P. MD, MPH 8; Turcotte, Lucie M. MD, MPH 8; Howell, Rebecca M. PhD 4,; Arnold, Michael A. MD 9,; Schaapveld, Michael PhD 6; Aleman, Berthe MD 6; Janus, Cecile MD 10; Versluys, Birgitta MD 2; Leisenring, Wendy ScD 11; Sklar, Charles A. MD 1,; Begg, Colin B. PhD 1; Pike, Malcolm C. PhD 1,; Armstrong, Gregory T. MD, MSCE 12; Robison, Leslie L. PhD 12; van Leeuwen, Flora E. PhD 6; Oeffinger, Kevin C. MD 13

doi : 10.1200/JCO.20.02244

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Short Androgen Suppression and Radiation Dose Escalation in Prostate Cancer: 12-Year Results of EORTC Trial 22991 in Patients With Localized Intermediate-Risk Disease.

Bolla, Michel MD 1,; Neven, Anouk MSc 2; Maingon, Philippe MD 3,; Carrie, Christian MD 4,; Boladeras, Ana MD 5; Andreopoulos, Demetrios MD 6; Engelen, Antoine MD 7; Sundar, Santhanam MD 8,; van der Steen-Banasik, Elzbieta M. MD 9; Armstrong, John MD 10,; Peignaux-Casasnovas, Karine MD 11; Boustani, Jihane MD 12; Herrera, Fernanda G. MD, PhD 13,; Pieters, Bradley R. MD, PhD 14,; Slot, Annerie MD 15; Bahl, Amit MD 16,; Scrase, Christopher D. MD 17; Azria, David MD, PhD 18,; Jansa, Jan MD 19,; O'Sullivan, Joe M. MD 20,; Van Den Bergh, Alphonsus C. M. MD, PhD 21; Collette, Laurence PhD 2,; for the EORTC Radiation Oncology Group

doi : 10.1200/JCO.21.00855

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Monitoring of Circulating Tumor DNA Improves Early Relapse Detection After Axicabtagene Ciloleucel Infusion in Large B-Cell Lymphoma: Results of a Prospective Multi-Institutional Trial.

Frank, Matthew J. MD, PhD 1,2,; Hossain, Nasheed M. MD 3; Bukhari, Ali MD 4; Dean, Erin MD 5; Spiegel, Jay Y. MD 1,2; Claire, Gursharan K. MPH 1,2; Kirsch, Ilan MD 6,; Jacob, Allison P. MS 6,; Mullins, Chelsea D. BA 6,; Lee, Lik Wee PhD 6,; Kong, Katherine A. MS 1,2; Craig, Juliana MS 1,2; Mackall, Crystal L. MD 1,2,7,; Rapoport, Aaron P. MD 4; Jain, Michael D. MD, PhD 5,; Dahiya, Saurabh MD 4,; Locke, Frederick L. MD 5,; Miklos, David B. MD, PhD 1,2,,

doi : 10.1200/JCO.21.00377

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Humanized CD19-Targeted Chimeric Antigen Receptor (CAR) T Cells in CAR-Naive and CAR-Exposed Children and Young Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia.

Myers, Regina M. MD 1; Li, Yimei PhD 1,2; Barz Leahy, Allison MD, MSCE 1; Barrett, David M. MD, PhD 1,3,; Teachey, David T. MD 1,3,; Callahan, Colleen MSN 1,; Fasano, Christina C. MSN 1; Rheingold, Susan R. MD 1,3,; DiNofia, Amanda MD, MSCE 1,3; Wray, Lisa MD 1,3; Aplenc, Richard MD, PhD 1,3,; Baniewicz, Diane MSN 1; Liu, Hongyan PhD 4; Shaw, Pamela A. PhD 2,; Pequignot, Edward MS 5,; Getz, Kelly D. PhD 2,3,6; Brogdon, Jennifer L. PhD 7,; Fesnak, Andrew D. MD 8; Siegel, Donald L. PhD, MD 5,8,; Davis, Megan M. PhD 5,8,; Bartoszek, Chelsie BS 5; Lacey, Simon F. PhD 5,8,; Hexner, Elizabeth O. MD, MSTR 5,9,; Chew, Anne PhD 5; Wertheim, Gerald B. MD, PhD 8,10,; Levine, Bruce L. PhD 8,; June, Carl H. MD 5,8,11,; Grupp, Stephan A. MD, PhD 1,3,; Maude, Shannon L. MD, PhD 1,3,5,,

doi : 10.1200/JCO.20.03458

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Management of the Axilla in Early-Stage Breast Cancer: Ontario Health (Cancer Care Ontario) and ASCO Guideline.

Brackstone, Muriel MD, PhD 1; Baldassarre, Fulvia G. MSc 2; Perera, Francisco E. MD 1 ,; Cil, Tulin MD, MEd 3 ,; Chavez Mac Gregor, Mariana MD, MSc 4 ,; Dayes, Ian S. MD 5 ,; Engel, Jay MBBCh 6; Horton, Janet K. MD 7 ,; King, Tari A. MD 8 ,; Kornecki, Anat MD 9 ,; George, Ralph MD 10 ,; SenGupta, Sandip K. MD 11; Spears, Patricia A. BS 12 ,; Eisen, Andrea F. MD 13 ,

doi : 10.1200/JCO.21.00934

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Last Hug.

Nabhan, Chadi MD, MBA 1,2,,

doi : 10.1200/JCO.21.00733

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Radiation Dose Escalation for Early Prostate Cancer: Reigniting the FLAME?.

Vogelius, Ivan R. PhD, DMSc; Bentzen, Soren M. PhD, DMSc

doi : 10.1200/JCO.21.00586

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Reply to I. R. Vogelius et al.

Kerkmeijer, Linda G. W. MD, PhD; Pos, Floris J. MD, PhD; Haustermans, Karin MD, PhD; van der Heide, Uulke A. PhD

doi : 10.1200/JCO.21.00789

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Regarding the Children's Oncology Group ARAR0332 Protocol for Pediatric Adrenocortical Carcinoma.

Wang, Ji-Gan MD; Mo, Dun-Chang MD

doi : 10.1200/JCO.21.00918

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Reply to J.-G. Wang et al.

Rodriguez-Galindo, Carlos MD; Krailo, Mark PhD; Pappo, Alberto MD; Ribeiro, Raul MD

doi : 10.1200/JCO.21.01389

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Who Can Receive the Benefit of a Palbociclib Add-On in Patients With HR+HER2- Breast Cancer With Residual Disease After Neoadjuvant Chemotherapy?.

Kawamura, Yukino MD; Shimomura, Akihiko MD, PhD; Shimizu, Chikako MD, PhD

doi : 10.1200/JCO.21.01174

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Reply to Y. Kawamura et al.

Loibl, Sibylle MD, PhD; Nekljudova, Valentina PhD; Denkert, Carsten MD, PhD

doi : 10.1200/JCO.21.01403

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Oral Azacitidine in Patients With Myelodysplastic Syndrome.

Shibusawa, Motoharu MD; Kidoguchi, Keisuke MD; Tanimoto, Tetsuya MD

doi : 10.1200/JCO.21.01126

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