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Epigenetic profiling of twins identify repression of KLF4 as a novel pathomechanism in systemic sclerosis
Jörg H W Distler, Steven O'Reilly
doi : 10.1136/annrheumdis-2021-221605
February 2022 - Volume 81 - 2
Baseline predictors of different types of treatment success in rheumatoid arthritis
Dafne Capelusnik, Daniel Aletaha
Perceptions and experiences of individuals at-risk of rheumatoid arthritis (RA) knowing about their risk of developing RA and being offered preventive treatment: systematic review and thematic synthesis of qualitative studies
Heidi J Siddle, Lara S Chapman, Kulveer Mankia, Codruța Zăbălan, Marios Kouloumas, Karim Raza, Marie Falahee, Joel Kerry, Andreas Kerschbaumer, Daniel Aletaha, Paul Emery, Suzanne H Richards
Joint inflammation tends to recur in the same joints during the rheumatoid arthritis disease course
Sascha L Heckert, Sytske Anne Bergstra, Xanthe M E Matthijssen, Yvonne P M Goekoop-Ruiterman, Faouzia Fodili, Saskia ten Wolde, Cornelia F Allaart, Tom W J Huizinga
Trajectory clusters of radiographic progression in patients with rheumatoid arthritis: associations with clinical variables
Alexander Platzer, Farideh Alasti, Josef S Smolen, Daniel Aletaha, Helga Radner, Stephan Blüml
Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years
Kevin L Winthrop, Yoshiya Tanaka, Tsutomu Takeuchi, Alan Kivitz, Franziska Matzkies, Mark C Genovese, Deyuan Jiang, Kun Chen, Beatrix Bartok, Angelika Jahreis, Robin Besuyen, Gerd R Burmester, Jacques-Eric Gottenberg
Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis
Achilleas Floudas, Nuno Neto, Carl Orr, Mary Canavan, Phil Gallagher, Conor Hurson, Michael G Monaghan, Sunil Nagpar, Ronan H Mullan, Douglas J Veale, Ursula Fearon
Incidence and risk factors for herpes zoster in patients with rheumatoid arthritis receiving upadacitinib: a pooled analysis of six phase III clinical trials
Kevin L Winthrop, Peter Nash, Kunihiro Yamaoka, Eduardo Mysler, Nasser Khan, Heidi S Camp, Yanna Song, Jessica L Suboticki, Jeffrey R Curtis
Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis
Rebecca A Symons, Fabio Colella, Fraser L Collins, Alexandra J Rafipay, Karolina Kania, Jessica J McClure, Nathan White, Iain Cunningham, Sadaf Ashraf, Elizabeth Hay, Kevin S Mackenzie, Kenneth A Howard, Anna H K Riemen, Antonio Manzo, Susan M Clark, Anke J Roelofs, Cosimo De Bari
Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 1 trial
Lars Erik Kristensen, Mauro Keiserman, Kim Papp, Leslie McCasland, Douglas White, Wenjing Lu, Zailong Wang, Ahmed M Soliman, Ann Eldred, Lisa Barcomb, Frank Behrens
Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study
Jeanette Trickey, Ilfita Sahbudin, Mads Ammitzbøll-Danielsen, Irene Azzolin, Carina Borst, Alessandra Bortoluzzi, George AW Bruyn, Philippe Carron, Coziana Ciurtin, Georgios Filippou, Jacek Fliciński, Daniela Fodor, Hélène Gouze, Marwin Gutierrez, Hilde Berner Hammer, Ellen-Margrethe Hauge, Annamaria Iagnocco, Kei Ikeda, Rositsa Karalilova, Helen Isobel Keen, Marion Kortekaas, Giuliana La Paglia, Gustavo Leon, Peter Mandl, Mihaela Maruseac, Marcin Milchert, Mohamed Atia Mortada, Esperanza Naredo, Sarah Ohrndorf, Carlos Pineda, Mads Nyhuus Bendix Rasch, Cristina Reátegui-Sokolova, Garifallia Sakellariou, Teodora Serban, Cesar A Sifuentes-Cantú, Maria S Stoenoiu, Takeshi Suzuki, Lene Terslev, Ilaria Tinazzi, Florentin Ananu Vreju, Ruth Wittoek, Maria-Antonietta D'Agostino, Andrew Filer
Choose wisely: imaging for diagnosis of axial spondyloarthritis
Torsten Diekhoff, Iris Eshed, Felix Radny, Katharina Ziegeler, Fabian Proft, Juliane Greese, Dominik Deppe, Robert Biesen, Kay Geert Hermann, Denis Poddubnyy
Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus
Huai-Chia Chuang, Wei-Ting Hung, Yi-Ming Chen, Pu-Ming Hsu, Jeng-Hsien Yen, Joung-Liang Lan, Tse-Hua Tan
Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages
Linyu Geng, Jian Zhao, Yun Deng, Ivan Molano, Xue Xu, Lingxiao Xu, Phillip Ruiz, Quanzhen Li, Xuebing Feng, Miaojia Zhang, Wenfeng Tan, Diane L Kamen, Sang-Cheol Bae, Gary S Gilkeson, Lingyun Sun, Betty P Tsao
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis
Maya Malaab, Ludivine Renaud, Naoko Takamura, Kip D Zimmerman, Willian A da Silveira, Paula S Ramos, Sandra Haddad, Marc Peters-Golden, Loka R Penke, Bethany Wolf, Gary Hardiman, Carl D Langefeld, Thomas A Medsger, Carol A Feghali-Bostwick
Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease
Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada
Clinical characteristics and outcomes of COVID-19 breakthrough infections among vaccinated patients with systemic autoimmune rheumatic diseases
Claire Cook, Naomi J Patel, Kristin M. D’Silva, Tiffany Y -T Hsu, Michael DiIorio, Lauren Prisco, Lily W Martin, Kathleen Vanni, Alessandra Zaccardelli, Derrick Todd, Jeffrey A Sparks, Zachary Scott Wallace
Booster-dose SARS-CoV-2 vaccination in patients with autoimmune disease: a case series
Caoilfhionn M Connolly, Mayan Teles, Sarah Frey, Brian J Boyarsky, Jennifer L Alejo, William A Werbel, Jemima Albayda, Lisa Christopher-Stine, Jacqueline Garonzik-Wang, Dorry L Segev, Julie J Paik
Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in patients with rheumatic and musculoskeletal diseases: a case series
Caoilfhionn M Connolly, Teresa Po-Yu Chiang, Brian J Boyarsky, Jake A Ruddy, Mayan Teles, Jennifer L Alejo, Allan Massie, William A Werbel, Ami A Shah, Lisa Christopher-Stine, Jacqueline Garonzik-Wang, Dorry L Segev, Julie J Paik
Inactivated vaccines may not provide adequate protection in immunosuppressed patients with rheumatic diseases
Padmanabha Shenoy, Sakir Ahmed, Aby Paul, Somy Cherian, Anuroopa Vijayan, Sageer AS Babu, Aswathy Sukumaran
Impact of sustaining SDAI remission for preventing incident of bone fragility fracture in patient with rheumatoid arthritis
Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa, Shohei Kokei
Fat mass and response to TNFα blockers in early axial spondyloarthritis: an analysis of the DESIR cohort
Anna Molto, Solange Tang, Bernard Combe, Maxime Dougados, Pascal Richette
Anti-ANP32A antibodies in systemic sclerosis
Rachel Wallwork, Livia Casciola-Rosen, Ami A Shah
The cost of arthralgia ‘pretreatment’ to prevent rheumatoid arthritis
Bruce M Rothschild1,2
Response to: ‘The cost of arthralgia ‘pretreatment’ to prevent rheumatoid arthritis’ by Rothschild
Annette van der Helm-van Mil, Robert BM Landewé
Effectiveness and safety of ruxolitinib for the treatment of refractory systemic idiopathic juvenile arthritis like associated with interstitial lung disease : a case report
Brigitte Bader-Meunier, Alice Hadchouel, Laureline Berteloot, Laura Polivka, Vivien Béziat, Jean-Laurent Casanova, Romain Lévy
Response to: ‘Effectiveness and safety of ruxolitinib for the treatment of refractory systemic idiopathic juvenile arthritis like associated with interstitial lung disease: case report’ by Bader-Meunier et al
Vivian E Saper, Guangbo Chen, Purvesh Khatri, Elizabeth D Mellins
Do 2019 European League against rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus also indicate the disease activity?
Jialin Teng, Zhuochao Zhou, Fan Wang, Yue Sun, Hong-Lei Liu, Xiaobing Cheng, Yutong Su, Hui Shi, Chengde Yang, Junna Ye
Response to: ‘Do 2019 European League against rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus also indicate the disease activity?’ by Teng et al
Martin Aringer, Karen Costenbader, Thomas Dörner, Sindhu R Johnson
Dupilumab as a potential steroid-sparing treatment for IgG4-related disease
Emanuel Della-Torre, Marco Lanzillotta, Mona-Rita Yacoub
Response to: ‘Dupilumab as a potential steroid-sparing treatment for IgG4-related disease’ by Della-Torre et al
Rachel S Simpson, Jason K Lee
Correspondence on: ‘Dupilumab as a novel steroid-sparing treatment for IgG4-related disease’ by Simpson et al
Mikael Ebbo, Benjamin De Sainte-Marie, Romain Muller, Christelle Piperoglou, Aurélie Grados, Frédéric Vély, Nicolas Schleinitz
Response to: ‘Correspondence on: ‘Dupilumab as a novel steroid-sparing treatment for IgG4-related disease’ by Simpson et al’ by Ebbo et al
Rachel S Simpson, Jason K Lee
Interleukin-4 as an emerging therapeutic target for IgG4-related disease
Mitsuhiro Akiyama, Yuko Kaneko, Tsutomu Takeuchi
Response to : ‘Interleukin-4 as a emerging target for IgG4-related disease’ by Akiyama et al
Rachel S Simpson, Jason K Lee
Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum
Zhao-Wei Gao, Xi Wang, Fang Lin, Ke Dong
Response to: ‘Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum’ by Gao et al
Pui Y Lee, Zhengping Huang, Michael S Hershfield, Peter A Nigrovic
Rheumatic disorders associated with immune checkpoint inhibitors: what about myositis? An analysis of the WHO’s adverse drug reactions database
Thủy Nguyễn, Alexandre Thibault Jacques Maria, Chayma Ladhari, Pascale Palassin, Xavier Quantin, Candice Lesage, Guillaume Taïeb, Xavier Ayrignac, Patricia Rullier, Dominique Hillaire-Buys, Olivier Lambotte, Philippe Guilpain, Jean-Luc Faillie
A case of episodic and refractory arthritis due to a novel variant of NLRP12
Jiajia Wang, Qian Zhang, Lingxiao Xu, Chengyin Lv, Rui Liu, Miaojia Zhang, Wenfeng Tan
Correction: Significant weight loss in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database
Correction: Emergent high fatality lung disease in systemic juvenile arthritis
