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Greetings from the editor 2022
1. Josef S Smolen
doi : 10.1136/annrheumdis-2021-221935
January 2022 - Volume 81 - 1
Re-examining remission definitions in rheumatoid arthritis: considering the 28-Joint Disease Activity Score, C-reactive protein level and patient global assessment
David Felson, Diane Lacaille, Michael P LaValley, Daniel Aletaha
Intercepting psoriatic arthritis in patients with psoriasis: buy one get one free?
Dennis G McGonagle, Alen Zabotti, Abdulla Watad, Charlie Bridgewood, Gabriele De Marco, Andreas Kerschbaumer, Daniel Aletaha
Significance of structural changes in the sacroiliac joints of patients with axial spondyloarthritis detected by MRI related to patients symptoms and functioning
Juergen Braun, Uta Kiltz, Xenofon Baraliakos
From sequential to combination and personalised therapy in lupus nephritis: moving towards a paradigm shift?
Ioannis Parodis, Frederic A Houssiau
EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis
György Nagy, Nadia M T Roodenrijs, Paco M J Welsing, Melinda Kedves, Attila Hamar, Marlies C van der Goes, Alison Kent, Margot Bakkers, Polina Pchelnikova, Etienne Blaas, Ladislav Senolt, Zoltan Szekanecz, Ernest H Choy, Maxime Dougados, Johannes WG Jacobs, Rinie Geenen, Johannes WJ Bijlsma, Angela Zink, Daniel Aletaha, Leonard Schoneveld, Piet van Riel, Sophie Dumas, Yeliz Prior, Elena Nikiphorou, Gianfranco Ferraccioli, Georg Schett, Kimme L Hyrich, Ulf Mueller-Ladner, Maya H Buch, Iain B McInnes, Désirée van der Heijde, Jacob M van Laar
2021 update of the EULAR points to consider on the use of immunomodulatory therapies in COVID-19
Alessia Alunno, Aurélie Najm, Pedro M Machado, Heidi Bertheussen, Gerd-Rüdiger R Burmester, Francesco Carubbi, Gabriele De Marco, Roberto Giacomelli, Olivier Hermine, John D Isaacs, Isabelle Koné-Paut, César Magro-Checa, Iain B McInnes, Pier Luigi Meroni, Luca Quartuccio, A V Ramanan, Manuel Ramos-Casals, Javier RodrÃguez Carrio, Hendrik Schulze-Koops, Tanja A Stamm, Sander W Tas, Benjamin Terrier, Dennis G McGonagle, Xavier Mariette
Risk of herpes zoster (shingles) in patients with rheumatoid arthritis under biologic, targeted synthetic and conventional synthetic DMARD treatment: data from the German RABBIT register
Imke Redeker, Katinka Albrecht, Joern Kekow, Gerd Rüdiger Burmester, Juergen Braun, Martin Schäfer, Angela Zink, Anja Strangfeld
Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis
Fenne Wouters, Marc P Maurits, Laurette van Boheemen, Marloes Verstappen, Kulveer Mankia, Xanthe M E Matthijssen, Annemarie L Dorjée, Paul Emery, Rachel Knevel, Dirkjan van Schaardenburg, René E M Toes, Annette H M van der Helm-van Mil
Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy
Alejandro Ibáñez-Costa, Carlos Perez-Sanchez, Alejandra MarÃa Patiño-Trives, Maria Luque-Tevar, Pilar Font, Ivan Arias de la Rosa, Cristobal Roman-Rodriguez, Mª Carmen Abalos-Aguilera, Carmen Conde, Antonio Gonzalez, Sergio Pedraza-Arevalo, Mercedes del Rio-Moreno, Ricardo Blazquez-Encinas, Pedro Segui, Jerusalem Calvo, Rafaela Ortega Castro, Alejandro Escudero-Contreras, Nuria Barbarroja, Mª Angeles Aguirre, Justo P Castaño, Raul M Luque, Eduardo Collantes-Estevez, Chary Lopez-Pedrera
Biological disease-modifying antirheumatic drugs may mitigate the risk of psoriatic arthritis in patients with chronic plaque psoriasis
Paolo Gisondi, Francesco Bellinato, Giovanni Targher, Luca Idolazzi, Giampiero Girolomoni
Treating the skin with biologics in patients with psoriasis decreases the incidence of psoriatic arthritis
Maria Laura Acosta Felquer, Luciano LoGiudice, Maria Laura Galimberti, Javier Rosa, Luis Mazzuoccolo, Enrique R Soriano
Does biologic therapy impact the development of PsA among patients with psoriasis?
Elana Meer, Joseph F Merola, Robert Fitzsimmons, Thorvardur Jon Love, Shiyu Wang, Daniel Shin, Yong Chen, Sharon Xie, Hyon Choi, Yuqing Zhang, Jose U Scher, C T Ritchlin, Joel M Gelfand, Alexis Ogdie
METTL3-mediated m6A modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progression
Xiang Chen, Wang Gong, Xiaoyan Shao, Tianshu Shi, Lei Zhang, Jian Dong, Yong Shi, Siyu Shen, Jianghui Qin, Qing Jiang, Baosheng Guo
B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial
Richard A Furie, Gustavo Aroca, Matthew D Cascino, Jay P Garg, Brad H Rovin, Analia Alvarez, Hilda Fragoso-Loyo, Elizabeth Zuta-Santillan, Thomas Schindler, Paul Brunetta, Cary M Looney, Imran Hassan, Ana Malvar
Integrative analysis of lung molecular signatures reveals key drivers of systemic sclerosis-associated interstitial lung disease
Seung Min Jung, Kyung-Su Park, Ki-Jo Kim
Treatment efficacy and safety of tofacitinib versus methotrexate in Takayasu arteritis: a prospective observational study
Xiufang Kong, Ying Sun, Xiaojuan Dai, Li Wang, Zongfei Ji, Huiyong Chen, Xuejuan Jin, Lili Ma, Lindi Jiang
Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis
Ignatius Ryan Adriawan, Faranaz Atschekzei, Oliver Dittrich-Breiholz, Panagiotis Garantziotis, Stefanie Hirsch, Linus Maximillian Risser, Maike Kosanke, Reinhold Ernst Schmidt, Torsten Witte, Georgios Sogkas
Native joint infections in Iceland 2003–2017: an increase in postarthroscopic infections
Signý Lea Gunnlaugsdóttir, Helga Erlendsdóttir, Kristján Orri Helgason, �rni Jón Geirsson, Valtýr Thors, Sigurður Guðmundsson, Magnús Gottfreðsson
Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA
Theresa Kissel, Tineke J van Wesemael, Anders Lundquist, Heidi Kokkonen, Atsushi Kawakami, Mami Tamai, Dirkjan van Schaardenburg, Manfred Wuhrer, Tom WJ Huizinga, Hans Ulrich Scherer, Diane van der Woude, Solbritt Rantapää-Dahlqvist, René E M Toes
B-cell targeted therapy is associated with severe COVID-19 among patients with inflammatory arthritides: a 1-year multicentre study in 1116 successive patients receiving intravenous biologics
Renaud Felten, Pierre-Marie Duret, Elodie Bauer, Nathanael Sedmak, Julien H Djossou, Massiva Bensalem, Marc Ardizzone, Marion Geoffroy, Angelique Fan, Marion Couderc, Jean Hugues Salmon, Laurent Messer, Rose-Marie Javier, Alain Meyer, Emmanuel Chatelus, Christelle Sordet, Luc Pijnenburg, Jérémy Fort, Marina Rinagel, Julia Walther, Cassandre Fabre, Laurent Arnaud, Jean Sibilia, Nicolas Meyer, Francis Berenbaum, isabelle Chary-Valckenaere, Martin Soubrier, Jérémie Sellam, Jacques-Eric Gottenberg
SARS-CoV-2 infection after vaccination in patients with inflammatory rheumatic and musculoskeletal diseases
Saskia Lawson-Tovey, Kimme L Hyrich, Laure Gossec, Anja Strangfeld, Loreto Carmona, Bernd Raffeiner, Gözde Kübra Yardımcı, Ludovic Trefond, Nicolas Roux, Ana Rodrigues, Charalampos Papagoras, Elsa F Mateus, Xavier Mariette, Pedro M Machado
Correspondence on ‘Shared epitope defines distinct associations of cigarette smoking with levels of anticitrullinated protein antibody and rheumatoid factor’ by Ishikawa et al
Cristina Regueiro, Antonio Gonzalez
Response to: ‘Corresponence on ‘Shared epitope defines distinct associations of cigarette smoking with levels of anticitrullinated protein antibody and rheumatoid factor’ by Ishikawa et al’ by Regueiro and Gonzalez
Yuki Ishikawa, Katsunori Ikari, Chikashi Terao
Causal association of gut microbiome on the risk of rheumatoid arthritis: a Mendelian randomisation study
Young Ho Lee
Response to: ‘Causal association of gut microbiome on the risk of rheumatoid arthritis: a Mendelian randomisation study’ by Lee
Jun Inamo
Polyfunctional TEM cells in psoriatic arthritis synovium skewed towards Th17 cells
Smriti K Raychaudhuri, Christine Abria, Siba P Raychaudhuri
Response to: ‘Polyfunctional TEM cells in psoriatic arthritis synovium skewed towards Th17 cells’ by Raychaudhuri et al
Mary Canavan, Sarah M Wade, Douglas J Veale, Ursula Fearon
Frequency of MRI changes suggestive of axial spondyloarthritis in the axial skeleton in a large population-based cohort of individuals aged <45 years
Konstantinos Parperis1,2
Response to: ‘Frequency of MRI changes suggestive of axial spondyloarthritis in the axial in a large population-based cohort of individuals aged <45 years’ by Parperis
Xenofon Baraliakos, Adrian Richter, Carsten O Schmidt, Juergen Braun
Correspondence on: ‘Irritable bowel syndrome symptoms in axial spondyloarthritis more common than among healthy controls: is it an overlooked comorbidity?’ by Wallman et al
Fabian Proft, Mikhail Protopopov, Valeria Rios Rodriguez, Murat Torgutalp, Britta Siegmund, Denis Poddubnyy
Response to: ‘Correspondence on: irritable bowel syndrome symptoms in axial spondyloarthritis more common than among healthy controls: is it an overlooked comorbidity?’ by Proft et al.
Johan Karlsson Wallman, Elisabeth Mogard, Jan Marsal, Kristofer Andréasson, Anna Jöud, Mats Geijer, Lars Erik Kristensen, Elisabet Lindqvist, Tor Olofsson
Efficacy and improved tolerability of combination therapy with interleukin-1 blockade and MAPK pathway inhibitors for the treatment of Erdheim-Chester disease
Corrado Campochiaro, Giulio Cavalli, Nicola Farina, Alessandro Tomelleri, Giacomo De Luca, Lorenzo Dagna
Response to: ‘Efficacy and improved tolerability of combination therapy with interleukin-1 blockade and MAPK pathway inhibitors for the treatment of Erdheim-Chester disease’ by Campochiaro et al
Fleur Cohen-Aubart, Neila Benameur, Zahir Amoura, Julien Haroche
Correspondence on 'Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation’ by Braaten et al
Fulvia Ceccarelli, Andrea Botticelli, Alain Jonathan Gelibter, Ilaria Leccese, Ramona Lucchetti, Enrico Cortesi, Guido Valesini, Paolo Marchetti, Fabrizio Conti
Response to: Correspondence on “Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation� by Braaten et al
Laura C Cappelli, Clifton O Bingham, Tawnie Braaten, Ami A Shah
Do we need the PFAPA syndrome in adults with non-monogenic periodic fevers?
Antoine Fayand, Veronique Hentgen, Stephanie Ducharme-Bénard, Pierre Quartier, Brigitte Bader-Meunier, Isabelle Koné-Paut, Gilles Grateau, Sophie Georgin-Lavialle
Response to: ‘Do we need the PFAPA syndrome in adults with non-monogenic periodic fevers?’ by Fayand et al
Marco Gattorno, Michael Hofer, Federica Vanoni, Silvia Federici, Luca Cantarini, Nicolino Ruperto
Correction: Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
