Diabetes




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In This Issue of Diabetes

Max Bingham, PhD

doi : 10.2337/db22-ti08

Volume 71, Issue 8

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A Special Thanks to Lyn Reynolds, Director of the ADA Editorial Office, as She Embarks on Her Retirement

Matthew C. Riddle, MD; David A. D’Alessio, MD; Stephen A. Brunton, MD; Curtis L. Triplitt, PharmD, CDCES

doi : 10.2337/db22-en08

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The β-Cell in Type 1 Diabetes Pathogenesis: A Victim of Circumstances or an Instigator of Tragic Events?

Roberto Mallone; Clémentine Halliez; Jinxiu Rui; Kevan C. Herold

doi : 10.2337/dbi21-0036

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Going With the Flow: Pericyte-Regulated Islet Blood Flow Influences Glucose Homeostasis

Jennifer K. Briggs; Anat Schonblum; Limor Landsman; Richard K.P. Benninger

doi : 10.2337/dbi22-0016

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The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass

Jason M. Spaeth; Sangeeta Dhawan

doi : 10.2337/dbi22-0010

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The Mechanism for Adipose Endotrophin Production

Yun Sok Lee

doi : 10.2337/dbi22-0008

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Metabolomic Markers in Early Pregnancy for Gestational Diabetes Mellitus

Liwei Chen

doi : 10.2337/dbi22-0015

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Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney

Elina Akalestou; Livia Lopez-Noriega; Iain R. Tough; Ming Hu; Isabelle Leclerc; Helen M. Cox; Guy A. Rutter

doi : 10.2337/db21-0768

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The Effect of Glucagon on Protein Catabolism During Insulin Deficiency: Exchange of Amino Acids Across Skeletal Muscle and the Splanchnic Bed

Haleigh James; Wilson I. Gonsalves; Shankarappa Manjunatha; Surendra Dasari; Ian R. Lanza; Katherine A. Klaus; Adrian Vella; James C. Andrews; K. Sreekumaran Nair

doi : 10.2337/db22-0079

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Infant Mesenchymal Stem Cell Insulin Action Is Associated With Maternal Plasma Free Fatty Acids, Independent of Obesity Status: The Healthy Start Study

Alec B. Chaves; Donghai Zheng; Jonathan A. Johnson; Bryan C. Bergman; Zachary W. Patinkin; Vincent Zaegel; Ericka M. Biagioni; Polina Krassovskaia; Nicholas T. Broskey; Linda E. May; Dana Dabelea; Joseph A. Houmard; Kristen E. Boyle

doi : 10.2337/db21-0812

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Roflumilast-Mediated Phosphodiesterase 4D Inhibition Reverses Diabetes-Associated Cardiac Dysfunction and Remodeling: Effects Beyond Glucose Lowering

Rui Xu; Jing Fu; Yuting Hu; Xiaoyan Yang; Xiang Tao; Long Chen; Kai Huang; Qin Fu

doi : 10.2337/db21-0898

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Pericyte Control of Blood Flow in Intraocular Islet Grafts Impacts Glucose Homeostasis in Mice

Alejandro Tamayo; Luciana Mateus Gonçalves; Rayner Rodriguez-Diaz; Elizabeth Pereira; Melissa Canales; Alejandro Caicedo; Joana Almaça

doi : 10.2337/db21-1104

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The Transcription Factor YY1 Is Essential for Normal DNA Repair and Cell Cycle in Human and Mouse β-Cells

Flavia Letícia Martins Peçanha; Rami Jaafar; Joao Pedro Werneck-de-Castro; Charalampia-Christina Apostolopolou; Anil Bhushan; Ernesto Bernal-Mizrachi

doi : 10.2337/db21-0908

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Targeting Pancreatic Islet NLRP3 Improves Islet Graft Revascularization

Selina Wrublewsky; Thimoteus Speer; Lisa Nalbach; Anne S. Boewe; Mandy Pack; Dalia Alansary; Leticia P. Roma; Markus D.A. Hoffmann; Beate M. Schmitt; Andrea Weinzierl; Michael D. Menger; Matthias W. Laschke; Emmanuel Ampofo

doi : 10.2337/db21-0851

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Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF

Yuki Nakafusa; Naoyoshi Nitta; Kazunari Ishii; Naoto Shirasu; Takahiro Iwamoto; Takayuki Nemoto; Masafumi Nakamura; Masafumi Goto; Hiroo Iwata; Masaru Taniguchi; Yohichi Yasunami

doi : 10.2337/db21-0684

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Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes

Yong Lin; Jelena Perovanovic; Yuelin Kong; Botond Z. Igyarto; Sandra Zurawski; Dean Tantin; Gerard Zurawski; Maria Bettini; Matthew L. Bettini

doi : 10.2337/db21-1069

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MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation

Woobeen Jo; Min Kim; Jiyoung Oh; Chu-Sook Kim; Chanho Park; Sora Yoon; Changhu Lee; Sahee Kim; Dougu Nam; Jiyoung Park

doi : 10.2337/db21-0801

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The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Giuseppina Biondi; Nicola Marrano; Lucia Dipaola; Anna Borrelli; Martina Rella; Rossella D’Oria; Valentina A. Genchi; Cristina Caccioppoli; Immacolata Porreca; Angelo Cignarelli; Sebastio Perrini; Piero Marchetti; Leonardo Vincenti; Luigi Laviola; Francesco Giorgino; Annalisa Natalicchio

doi : 10.2337/db21-1066

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New Evidence of Central Nervous System Damage in Diabetes: Impairment of Fine Visual Discrimination

He Chen; Menghan Wang; Lin Xia; Jiong Dong; Guangwei Xu; Ziyi Wang; Lixia Feng; Yifeng Zhou

doi : 10.2337/db21-0715

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Diabetic Neuropathy in Hands: An Endemic Complication Waiting to Unfold?

Eva Sierra-Silvestre; Ricardo J. Andrade; Andrea C. Schroeter; Leanne Bisset; Michel W. Coppieters

doi : 10.2337/db21-1147

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Plasma apoM Levels and Progression to Kidney Dysfunction in Patients With Type 1 Diabetes

Nathaniel L. Baker; Samar M. Hammad; Kelly J. Hunt; Andrea Semler; Richard L. Klein; Maria F. Lopes-Virella

doi : 10.2337/db21-0920

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Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes

Francesca D’Addio; Gianmarco Sabiu; Vera Usuelli; Emma Assi; Ahmed Abdelsalam; Anna Maestroni; Andy Joe Seelam; Moufida Ben Nasr; Cristian Loretelli; Davide Mileto; Giada Rossi; Ida Pastore; Laura Montefusco; Paola S. Morpurgo; Laura Plebani; Antonio Rossi; Enrica Chebat; Andrea M. Bolla; Maria Elena Lunati; Chiara Mameli; Maddalena Macedoni; Spinello Antinori; Stefano Rusconi; Maurizio Gallieni; Cesare Berra; Franco Folli; Massimo Galli; Maria Rita Gismondo; Gianvincenzo Zuccotti; Paolo Fiorina

doi : 10.2337/db22-0053

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Predictive Metabolomic Markers in Early to Mid-pregnancy for Gestational Diabetes Mellitus: A Prospective Test and Validation Study

Yeyi Zhu; Dinesh K. Barupal; Amanda L. Ngo; Charles P. Quesenberry; Juanran Feng; Oliver Fiehn; Assiamira Ferrara

doi : 10.2337/db21-1093

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Causal Graph Among Serum Lipids and Glycemic Traits: A Mendelian Randomization Study

Ziwei Zhu; Kai Wang; Xingjie Hao; Liangkai Chen; Zhonghua Liu; Chaolong Wang

doi : 10.2337/db21-0734

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Erratum. Hepatic CPT1A Facilitates Liver–Adipose Cross Talk via Induction of FGF21 in Mice. Diabetes 2022;71:31–42

Wei Sun; Tao Nie; Kuai Li; Wenjie Wu; Qiaoyun Long; Tianshi Feng; Liufeng Mao; Yuan Gao; Qing Liu; Xuefei Gao; Dewei Ye; Kaixuan Yan; Ping Gu; Yong Xu; Xuemei Zhao; Kang Chen; Kerry Martin Loomes; Shaoqiang Lin; Donghai Wu; Xiaoyan Hui

doi : 10.2337/db22-er08a

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