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Deciphering the vedolizumab dosing conundrum in IBD: when less is more
Timon Erik Adolph, Britta Siegmund
doi : 10.1136/gutjnl-2021-325893
August 2022 - Volume 71 - 8
Real-world data for endoscopic therapy in LGD: not looking so good
Sachin Srinivasan, Prateek Sharma
British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the diagnosis and management of eosinophilic oesophagitis in children and adults
Anjan Dhar, Hasan N Haboubi, Stephen E Attwood, Marcus K H Auth, Jason M Dunn, Rami Sweis, Danielle Morris, Jenny Epstein, Marco R Novelli, Hannah Hunter, Amanda Cordell, Sharon Hall, Jamal O Hayat, Kapil Kapur, Andrew Robert Moore, Carol Read, Sarmed S Sami, Paul J Turner, Nigel J Trudgill
Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction
Kentaro Sugano, Stuart Jon Spechler, Emad M El-Omar, Kenneth E L McColl, Kaiyo Takubo, Takuji Gotoda, Mitsuhiro Fujishiro, Katsunori Iijima, Haruhiro Inoue, Takashi Kawai, Yoshikazu Kinoshita, Hiroto Miwa, Ken-ichi Mukaisho, Kazunari Murakami, Yasuyuki Seto, Hisao Tajiri, Shobna Bhatia, Myung-Gyu Choi, Rebecca C Fitzgerald, Kwong Ming Fock, Khean-Lee Goh, Khek Yu Ho, Varocha Mahachai, Maria O'Donovan, Robert Odze, Richard Peek, Massimo Rugge, Prateek Sharma, Jose D Sollano, Michael Vieth, Justin Wu, Ming-Shiang Wu, Duowu Zou, Michio Kaminishi, Peter Malfertheiner
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis
Ruby E Dawson, Virginie Deswaerte, Alison C West, Ke Tang, Alice J West, Jesse J Balic, Linden J Gearing, Mohamed I Saad, Liang Yu, Yonghui Wu, Prithi S Bhathal, Beena Kumar, Jayati T Chakrabarti, Yana Zavros, Hiroko Oshima, Dennis M Klinman, Masanobu Oshima, Patrick Tan, Brendan J Jenkins
International variation in oesophageal and gastric cancer survival 2012–2014: differences by histological subtype and stage at diagnosis (an ICBP SURVMARK-2 population-based study)
Melina Arnold, Eileen Morgan, Aude Bardot, Mark J Rutherford, Jacques Ferlay, Alana Little, Bjorn Møller, Oliver Bucher, Prithwish De, Ryan R Woods, Nathalie Saint-Jacques, Anna T Gavin, Gerda Engholm, Michael P Achiam, Geoff Porter, Paul M Walsh, Sally Vernon, Serena Kozie, Agnihotram V Ramanakumar, Charlotte Lynch, Samantha Harrison, Neil Merrett, Dianne L O’Connell, Tom Mala, Mark Elwood, John Zalcberg, Dyfed W Huws, David Ransom, Freddie Bray, Isabelle Soerjomataram
Timing of endoscopy for acute upper gastrointestinal bleeding: a territory-wide cohort study
Cosmos L T Guo, Sunny H Wong, Louis H S Lau, Rashid N S Lui, Joyce W Y Mak, Raymond S Y Tang, Terry C F Yip, William K K Wu, Grace L H Wong, Francis K L Chan, James Y W Lau, Joseph J Y Sung
Residual homing of α4β7-expressing β1+PI16+ regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab
Emily Becker, Mark Dedden, Christine Gall, Maximilian Wiendl, Arif Bülent Ekici, Anja Schulz-Kuhnt, Anna Schweda, Caroline Voskens, Ahmed Hegazy, Francesco Vitali, Raja Atreya, Tanja Martina Müller, Imke Atreya, Markus F Neurath, Sebastian Zundler
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome
Christian Bojarski, Paul Tangermann, Christian Barmeyer, Juliane Buchkremer, Ralf Kiesslich, Mark Ellrichmann, Stefan Schreiber, Carsten Schmidt, Andreas Stallmach, Robert Roehle, Christoph Loddenkemper, Severin Daum, Britta Siegmund, Michael Schumann, Reiner Ullrich
Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
Annefleur Koopen, Julia Witjes, Koen Wortelboer, Soumia Majait, Andrei Prodan, Evgeni Levin, Hilde Herrema, Maaike Winkelmeijer, Steven Aalvink, Jacques J G H M Bergman, Stephan Havik, Bolette Hartmann, Han Levels, Per-Olof Bergh, Jamie van Son, Manon Balvers, Diogo Mendes Bastos, Erik Stroes, Albert K Groen, Marcus Henricsson, Ellis Marleen Kemper, Jens Holst, Christopher M Strauch, Stanley L Hazen, Fredrik Bäckhed, Willem M De Vos, Max Nieuwdorp, Elena Rampanelli
Deviated and early unsustainable stunted development of gut microbiota in children with autism spectrum disorder
Mingxing Lou, Aihua Cao, Cuiyuan Jin, Kai Mi, Xiyue Xiong, Zhaoyang Zeng, Xu Pan, Jinlong Qie, Shangfeng Qiu, Yaofang Niu, Hao Liang, Yanping Liu, Lin Chen, Zhi Liu, Qing Zhao, Xiyan Qiu, Yuanxiang Jin, Xiaoqi Sheng, Zhibin Hu, Gulei Jin, Jingshi Liu, Xingyin Liu, Yichao Wang
Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)
Manuela Salvucci, Nyree Crawford, Katie Stott, Susan Bullman, Daniel B Longley, Jochen H M Prehn
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
Steffie Revia, Agnieszka Seretny, Lena Wendler, Ana Banito, Christoph Eckert, Kersten Breuer, Anand Mayakonda, Pavlo Lutsik, Matthias Evert, Silvia Ribback, Suchira Gallage, Ismaiel Chikh Bakri, Kai Breuhahn, Peter Schirmacher, Stefan Heinrich, Matthias M Gaida, Mathias Heikenwälder, Diego F Calvisi, Christoph Plass, Scott W Lowe, Darjus F Tschaharganeh
Discontinuation of nucleot(s)ide analogue therapy in HBeAg-negative chronic hepatitis B: a meta-analysis
Samuel Anthony Lachlan Hall, Sara Vogrin, Olivia Wawryk, Gareth S Burns, Kumar Visvanathan, Vijaya Sundararajan, Alexander Thompson
MicroRNA-206 promotes the recruitment of CD8+ T cells by driving M1 polarisation of Kupffer cells
Ningning Liu, Xiaomei Wang, Clifford John Steer, Guisheng Song
Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression
Lei Zhou, Ken HO Yu, Tin Lok Wong, Zhao Zhang, Chun Ho Chan, Jane HC Loong, Noelia Che, Hua Jian Yu, Kel Vin Tan, Man Tong, Elly S Ngan, Joshua WK Ho, Stephanie Ma
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions
Rocio I R Macias, Vincenzo Cardinale, Timothy J Kendall, Matias A Avila, Maria Guido, Cedric Coulouarn, Chiara Braconi, Adam E Frampton, John Bridgewater, Diletta Overi, Stephen P Pereira, Marco Rengo, Jakob N Kather, Angela Lamarca, Federica Pedica, Alejandro Forner, Juan W Valle, Eugenio Gaudio, Domenico Alvaro, Jesus M Banales, Guido Carpino
Pancreatic cancer: an increasing global public health concern
Citadel J Cabasag, Jacques Ferlay, Mathieu Laversanne, Jerome Vignat, Andras Weber, Isabelle Soerjomataram, Freddie Bray
Long-term use of proton pump inhibitors (PPIs) is associated with an increased risk of type 2 diabetes
Sven H Loosen, Karel Kostev, Mark Luedde, Natalia Qvartskhava, Tom Luedde, Christoph Roderburg
Letter to the editor: Genetically determined IBD is associated with decreased risk of Alzheimer’s disease: a Mendelian randomisation study
Xingzhi Guo, Li Chong, Xin Zhang, Rui Li
Correspondence to proton pump inhibitors and risk of colorectal cancer
Chen Dong, Yun-Hsun Lee, Tzu-Yang Tan, Chung-Chin Yao, James Cheng-Chung Wei
Response by Abrahami et al to letter regarding article ‘Proton pump inhibitors and risk of colorectal cancer’
Devin Abrahami, Laurent Azoulay
Clinical characteristics, hospitalisation and mortality rates of COVID-19 among patients with coeliac disease in the USA: a multicentre network study
Emad Mansoor, Muhammed Mustafa Alikhan, Jaime Abraham Perez, Kayla Schlick, Mohannad Abou Saleh, Alberto Rubio-Tapia
Unusual cause of abdominal pain and papule
He Zhou, Fenrong Chen, Jiayao Wang, Xin Liu, Jie Liang
Correction: Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-19
Correction: Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19
