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Hepatic GSK3β-Dependent CRY1 Degradation Contributes to Diabetic Hyperglycemia
Ye Young Kim; Hagoon Jang; Gung Lee; Yong Geun Jeon; Jee Hyung Sohn; Ji Seul Han; Won Taek Lee; Jeu Park; Jin Young Huh; Hahn Nahmgoong; Sang Mun Han; Jeesoo Kim; Minwoo Pak; Sun Kim; Jong-Seo Kim; Jae Bum Kim
doi : 10.2337/db21-0649
Volume 71, Issue 7
GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling
Elisabeth M. Grande; Fitore Raka; Simon Hoffman; Khosrow Adeli
doi : 10.2337/db21-1053
Endothelial Prohibitin Mediates Bidirectional Long-Chain Fatty Acid Transport in White and Brown Adipose Tissues
Zhanguo Gao; Alexes C. Daquinag; Yongmei Yu; Mikhail G. Kolonin
doi : 10.2337/db21-0972
GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior
Ricardo J. Samms; Richard Cosgrove; Brandy M. Snider; Ellen C. Furber; Brian A. Droz; Daniel A. Briere; James Dunbar; Mridula Dogra; Jorge Alsina-Fernandez; Tito Borner; Bart C. De Jonghe; Matthew R. Hayes; Tamer Coskun; Kyle W. Sloop; Paul J. Emmerson; Minrong Ai
doi : 10.2337/db21-0848
Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance
Sinju Sundaresan; Joseph Antoun; Babak Banan; Jamie Adcock; Connor Johnson; Brendan Claire; Kala Dixon; Joyce Flynn; Cyndya A. Shibao; Naji Abumrad
doi : 10.2337/db21-0708
β-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes
Sooyeon Lee; Haixia Xu; Aidan Van Vleck; Alex M. Mawla; Albert Mao Li; Jiangbin Ye; Mark O. Huising; Justin P. Annes
doi : 10.2337/db21-0834
Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents
Ya-Qin Du; Xue-Ying Sha; Jie Cheng; Jin Wang; Jing-Yu Lin; Wen-Tao An; Wei Pan; Li-Jun Zhang; Xiao-Na Tao; Yun-Fei Xu; Ying-Li Jia; Zhao Yang; Peng Xiao; Ming Liu; Jin-Peng Sun; Xiao Yu
doi : 10.2337/db21-0794
Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion
Eleni Georgiadou; Charanya Muralidharan; Michelle Martinez; Pauline Chabosseau; Elina Akalestou; Alejandra Tomas; Fiona Yong Su Wern; Theodoros Stylianides; Asger Wretlind; Cristina Legido-Quigley; Ben Jones; Livia Lopez-Noriega; Yanwen Xu; Guoqiang Gu; Nour Alsabeeh; Céline Cruciani-Guglielmacci; Christophe Magnan; Mark Ibberson; Isabelle Leclerc; Yusuf Ali; Scott A. Soleimanpour; Amelia K. Linnemann; Tristan A. Rodriguez; Guy A. Rutter
doi : 10.2337/db21-0800
Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis
Linda Yip; Reem Alkhataybeh; Cariel Taylor; Rebecca Fuhlbrigge; C. Garrison Fathman
doi : 10.2337/db21-0948
HIF-2α Preserves Mitochondrial Activity and Glucose Sensing in Compensating β-Cells in Obesity
Jae-Su Moon; Matthew Riopel; Jong Bae Seo; Vicente Herrero-Aguayo; Roi Isaac; Yun Sok Lee
doi : 10.2337/db21-0736
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
Rebecca Cheung; Grazia Pizza; Pauline Chabosseau; Delphine Rolando; Alejandra Tomas; Thomas Burgoyne; Zhiyi Wu; Anna Salowka; Anusha Thapa; Annabel Macklin; Yufei Cao; Marie-Sophie Nguyen-Tu; Matthew T. Dickerson; David A. Jacobson; Piero Marchetti; James Shapiro; Lorenzo Piemonti; Eelco de Koning; Isabelle Leclerc; Karim Bouzakri; Kei Sakamoto; David M. Smith; Guy A. Rutter; Aida Martinez-Sanchez
doi : 10.2337/db21-0803
Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity
Lauar de Brito Monteiro; Juliana Silveira Prodonoff; Cristhiane Favero de Aguiar; Felipe Correa-da-Silva; Angela Castoldi; Nikki van Teijlingen Bakker; Gustavo Gastão Davanzo; Bianca Castelucci; Jéssica Aparecida da Silva Pereira; Jonathan Curtis; Jörg Büscher; Larissa Menezes dos Reis; Gisele Castro; Guilherme Ribeiro; João Victor VirgÃlio-da-Silva; Douglas Adamoski; Sandra Martha Gomes Dias; Silvio Roberto Consonni; Jose Donato, Jr.; Edward J. Pearce; Niels Olsen Saraiva Câmara; Pedro M. Moraes-Vieira
doi : 10.2337/db21-0842
lncRNA-H19 in Fibroblasts Promotes Wound Healing in Diabetes
Pijun Yu; Jian Guo; Junjie Li; Xiao Shi; Ning Xu; Yongkang Jiang; Wei Chen; Qin Hu
doi : 10.2337/db21-0724
Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets
Moufida Ben Nasr; Francesca D’Addio; Laura Montefusco; Vera Usuelli; Cristian Loretelli; Antonio Rossi; Ida Pastore; Ahmed Abdelsalam; Anna Maestroni; Marco Dell’Acqua; Elio Ippolito; Emma Assi; Andy Joe Seelam; Roberta Maria Fiorina; Enrica Chebat; Paola Morpurgo; Maria Elena Lunati; Andrea Mario Bolla; Reza Abdi; Joseph V. Bonventre; Stefano Rusconi; Agostino Riva; Domenico Corradi; Pierachille Santus; Pamela Clark; Manuela Nebuloni; Gabriella Baldi; Giovanna Finzi; Franco Folli; Gian Vincenzo Zuccotti; Massimo Galli; Kevan C. Herold; Paolo Fiorina
doi : 10.2337/db21-0926
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration
Alice L.J. Carr; Jamie R.J. Inshaw; Christine S. Flaxman; Pia Leete; Rebecca C. Wyatt; Lydia A. Russell; Matthew Palmer; Dmytro Prasolov; Thomas Worthington; Bethany Hull; Linda S. Wicker; David B. Dunger; Richard A. Oram; Noel G. Morgan; John A. Todd; Sarah J. Richardson; Rachel E.J. Besser
doi : 10.2337/db22-0097
