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T-Cell Autoreactivity in Type 2 Diabetes: Benign or Pathogenic, Smoke or Fire?
Angus G. Jones; Martin Eichmann
doi : 10.2337/dbi22-0007
Volume 71, Issue 6
Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation
Joji Kusuyama; Nathan S. Makarewicz; Brent G. Albertson; Ana Barbara Alves-Wagner; Royce H. Conlin; Noah B. Prince; Christiano R.R. Alves; Krithika Ramachandran; Chisayo Kozuka; Yang Xiudong; Yang Xia; Michael F. Hirshman; Toshihisa Hatta; Ryoichi Nagatomi; Eva S. Nozik; Laurie J. Goodyear
doi : 10.2337/db21-0706
Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits
Loren Skudder-Hill; Ivana R. Sequeira; Jaelim Cho; Juyeon Ko; Sally D. Poppitt; Maxim S. Petrov
doi : 10.2337/db21-0976
Impaired Cold-Stimulated Supraclavicular Brown Adipose Tissue Activity in Young Boys With Obesity
Basma A. Ahmed; Nina Varah; Frank J. Ong; Denis P. Blondin; Elizabeth Gunn; Norman B. Konyer; Nina P. Singh; Michael D. Noseworthy; Francois Haman; Andre C. Carpentier; Zubin Punthakee; Gregory R. Steinberg; Katherine M. Morrison
doi : 10.2337/db21-0799
p38α Deficiency in T Cells Ameliorates Diet-Induced Obesity, Insulin Resistance, and Adipose Tissue Senescence
Deyun Meng; Baohua Zhang; Yanyan Wang; Tingting Zheng; Ran Hu; Bin Wang; Kinya Otsu; Ying Wang; Gonghua Huang
doi : 10.2337/db21-0653
Very-Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation
Anne-Laure Castell; Alexis Vivoli; Trevor S. Tippetts; Isabelle Robillard Frayne; Zuraya Elisa Angeles; Valentine S. Moullé; Scott A. Campbell; Matthieu Ruiz; Julien Ghislain; Christine Des Rosiers; William L. Holland; Scott A. Summers; Vincent Poitout
doi : 10.2337/db21-0640
Genetic Reduction of Glucose Metabolism Preserves Functional β-Cell Mass in KATP-Induced Neonatal Diabetes
Zihan Yan; Manuela Fortunato; Zeenat A. Shyr; Amy L. Clark; Matt Fuess; Colin G. Nichols; Maria S. Remedi
doi : 10.2337/db21-0992
DOC2b Enhances β-Cell Function via a Novel Tyrosine Phosphorylation-Dependent Mechanism
Diti Chatterjee Bhowmick; Arianne Aslamy; Supriyo Bhattacharya; Eunjin Oh; Miwon Ahn; Debbie C. Thurmond
doi : 10.2337/db21-0681
Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study
Barbara Brooks-Worrell; Christiane S. Hampe; Erica G. Hattery; Brenda Palomino; Sahar Z. Zangeneh; Kristina Utzschneider; Steven E. Kahn; Mary E. Larkin; Mary L. Johnson; Kieren J. Mather; Naji Younes; Neda Rasouli; Cyrus Desouza; Robert M. Cohen; Jean Y. Park; Hermes J. Florez; Willy Marcos Valencia; GRADE β-cell Ancillary Study Network; Ali Shojaie; Jerry P. Palmer; Ashok Balasubramanyam; for the GRADE Research Group
doi : 10.2337/db21-0590
Rate-Dependent Depression: A Predictor of the Therapeutic Efficacy in Treating Painful Diabetic Peripheral Neuropathy
Xiajun Zhou; Ying Zhu; Ze Wang; Zhi Lin; Desheng Zhu; Chong Xie; Nigel A. Calcutt; Yangtai Guan
doi : 10.2337/db21-0960
Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways
Jay C. Jha; Aozhi Dai; Jessica Garzarella; Amelia Charlton; Sofia Urner; Jakob A. Østergaard; Jun Okabe; Chet E. Holterman; Alison Skene; David A. Power; Elif I. Ekinci; Melinda T. Coughlan; Harald H.H.W. Schmidt; Mark E. Cooper; Rhian M. Touyz; Chris R. Kennedy; Karin Jandeleit-Dahm
doi : 10.2337/db21-1079
The Role of Long Noncoding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of Its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide
Akiko Miyashita; Masaki Kobayashi; Satoru Ishibashi; Tetsuya Nagata; Ambika Chandrasekhar; Douglas W. Zochodne; Takanori Yokota
doi : 10.2337/db21-0918
Blood Neuroexosomal Mitochondrial Proteins Predict Alzheimer Disease in Diabetes
Haiyan Chi; Ran Yao; Chao Sun; Bing Leng; Tengqun Shen; Tong Wang; Shukun Zhang; Mengfan Li; Yachao Yang; Hairong Sun; Zhenguang Li; Jinbiao Zhang
doi : 10.2337/db21-0969
Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study
Faegheh Ghanbari; Nahid Yazdanpanah; Mojgan Yazdanpanah; J. Brent Richards; Despoina Manousaki
doi : 10.2337/db21-1046
Serum Metabolomics of Incident Diabetes and Glycemic Changes in a Population With High Diabetes Burden: The Hispanic Community Health Study/Study of Latinos
Jin Choul Chai; Guo-Chong Chen; Bing Yu; Jiaqian Xing; Jun Li; Tasneem Khambaty; Krista M. Perreira; Marisa J. Perera; Denise C. Vidot; Sheila F. Castaneda; Elizabeth Selvin; Casey M. Rebholz; Martha L. Daviglus; Jianwen Cai; Linda Van Horn; Carmen R. Isasi; Qi Sun; Meredith Hawkins; Xiaonan Xue; Eric Boerwinkle; Robert C. Kaplan; Qibin Qi
doi : 10.2337/db21-1056
Genome-Wide Association Study Identifies Genetic Loci Associated With Fat Cell Number and Overlap With Genetic Risk Loci for Type 2 Diabetes
Agné Kulyté; Alisha Aman; Rona J. Strawbridge; Peter Arner; Ingrid A. Dahlman
doi : 10.2337/db21-0804
Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes
Maria Giovanna Scarale; Mario Mastroianno; Cornelia Prehn; Massimiliano Copetti; Lucia Salvemini; Jerzy Adamski; Salvatore De Cosmo; Vincenzo Trischitta; Claudia Menzaghi
doi : 10.2337/db22-0095
Erratum. The Women’s Leadership Gap in Diabetes: A Call for Equity and Excellence. Diabetes 2021;70:1623–1633
Jessica L. Dunne; Jennifer L. Maizel; Amanda L. Posgai; Mark A. Atkinson; Linda A. DiMeglio
doi : 10.2337/db22-er06a
