New England Journal of Medicine




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Designing Cures 2.0 — From Corridors to Cornerstones

Kushal T. Kadakia, M.Sc., and Harlan M. Krumholz, M.D.

doi : 10.1056/NEJMp2200203

Vol. 386 No. 18

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Real-World Evidence — Where Are We Now?

John Concato, M.D., M.P.H., and Jacqueline Corrigan-Curay, J.D., M.D.

doi : 10.1056/NEJMp2200089

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Supporting Health Care Workers to Address Misinformation on Social Media

Vineet M. Arora, M.D., M.A.P.P., Eve Bloomgarden, M.D., and Shikha Jain, M.D.

doi : 10.1056/NEJMp2117180

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Two Phase 3 Trials of Baricitinib for Alopecia Areata

Brett King, M.D., Ph.D., Manabu Ohyama, M.D., Ph.D., Ohsang Kwon, M.D., Ph.D., Abraham Zlotogorski, M.D., Justin Ko, M.D., Natasha A. Mesinkovska, M.D

doi : 10.1056/NEJMoa2110343

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Early Outpatient Treatment for Covid-19 with Convalescent Plasma

David J. Sullivan, M.D., Kelly A. Gebo, M.D., M.P.H., Shmuel Shoham, M.D., Evan M. Bloch, M.B., Ch.B., Bryan Lau, Ph.D., Aarthi G. Shenoy, M.D., Gisel

doi : 10.1056/NEJMoa2119657

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Protection by a Fourth Dose of BNT162b2 against Omicron in Israel

Yinon M. Bar-On, M.Sc., Yair Goldberg, Ph.D., Micha Mandel, Ph.D., Omri Bodenheimer, M.Sc., Ofra Amir, Ph.D., Laurence Freedman, Ph.D., Sharon Alroy-P

doi : 10.1056/NEJMoa2201570

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Effect of Early Treatment with Ivermectin among Patients with Covid-19

Gilmar Reis, M.D., Ph.D., Eduardo A.S.M. Silva, M.D., Ph.D., Daniela C.M. Silva, M.D., Ph.D., Lehana Thabane, Ph.D., Aline C. Milagres, R.N., Thiago S

doi : 10.1056/NEJMoa2115869

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Nonspecific Low Back Pain

Alessandro Chiarotto, P.T., Ph.D., and Bart W. Koes, Ph.D.

doi : 10.1056/NEJMcp2032396

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Foreign-Body Aspiration in a Child

Katarzyna M. Saar, D.O., and Christopher R. Grindle, M.D.

doi : 10.1056/NEJMicm2115363

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Primary Cutaneous Blastomycosis

Albert Alhatem, M.D., and Kristin C. Smith, M.D.

doi : 10.1056/NEJMicm2116178

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Looking Back

Lauren Glick, M.D., Laura A. Fitzpatrick, M.D., Allan S. Detsky, M.D., Ph.D., and Raphael P. Rush, M.D.

doi : 10.1056/NEJMcps2117782

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Baricitinib in Alopecia Areata

Andrew Messenger, M.D., and Matthew Harries, Ph.D.

doi : 10.1056/NEJMe2203440

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Convalescent Plasma for Covid-19 — Making Sense of the Inconsistencies

Lise Estcourt, M.B., B.Chir., and Jeannie Callum, M.D.

doi : 10.1056/NEJMe2204332

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Audio Interview: Do We Need New Covid-19 Vaccines?

Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.

doi : 10.1056/NEJMe2205974

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A New Image for Cell Sorting

Andrew Filby, Ph.D., and Anne E. Carpenter, Ph.D.

doi : 10.1056/NEJMcibr2200971

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Metric Myopia — Trading Away Our Clinical Judgment

Lisa Rosenbaum, M.D.

doi : 10.1056/NEJMms2200977

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Neutralization Profile after Recovery from SARS-CoV-2 Omicron Infection

doi : 10.1056/NEJMc2201607

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Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis

doi : 10.1056/NEJMc2202778

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Trastuzumab Deruxtecan in Non–Small-Cell Lung Cancer

doi : 10.1056/NEJMc2202305

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Pembrolizumab in Early Triple-Negative Breast Cancer

doi : 10.1056/NEJMc2203316

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