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Chasing Methuselah: adult inducible GHRKO mice

John J. Kopchick, Darlene E. Berryman, Edward O. List

doi : 10.18632/aging.204016

Volume 14, Issue 8

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Intensive fasting reduces thrombosis and improves innate immunity

Yanjun Yang, Jianrong Wang

doi : 10.18632/aging.204020

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SNCA-AS1 in aging and Parkinson’s disease

Stephana Carelli, Federica Rey, Cristina Cereda

doi : 10.18632/aging.204025

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Muscle fiber type-dependence effect of exercise on genomic networks in aged mice models

Sun Min Lee, Min Chul Lee, Woo Ri Bae, Kyung Jin Yoon, Hyo Youl Moon

doi : 10.18632/aging.204024

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Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties

James A. McCubrey, Akshaya K. Meher, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Michelle M. LaHair, Richard A. Franklin, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Fulvio Barbaro, Przemysław Duda, Agnieszka Gizak

doi : 10.18632/aging.204038

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miRNA-142-3p functions as a potential tumor suppressor directly targeting FAM83D in the development of ovarian cancer

Guangyu Gao, Xiaofei Guo, Wenyong Gu, Yufeng Lu, Zhigang Chen

doi : 10.18632/aging.203998

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Circular RNA circ_0000423 regulates cartilage ECM synthesis via circ_0000423/miRNA-27b-3p/MMP-13 axis in osteoarthritis

Xing Li, Chaofan Xie, Fangjun Xiao, Haitao Su, Zhen Li, Jiaxian Weng, Yongming Huang, Peiheng He

doi : 10.18632/aging.204018

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The effect of D-chiro-inositol on renal protection in diabetic mice

Chunxue Fan, Dandan Zhang, Junling Zhang, Jinwei Li, Yu Wang, Linghuan Gao, Shuying Han

doi : 10.18632/aging.204019

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Molecular characterization of matrix metalloproteinase gene family across primates

Yinglian Pan, Yadan Fan, Yanda Lu, Siyuan Peng, Haixue Lin, Qingchun Deng

doi : 10.18632/aging.204021

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Integrated analysis of 14 lymphoma datasets revealed high expression of CXCL14 promotes cell migration in mantle cell lymphoma

Dahai Liu, Fei Qi, Wei Liu, Justin Liu, Jun Wang, Dao-Qiang Lu, Yang Xun, Min-Min Chen, Xin Chen, Shu-Ting Yang, Wen-Qiao Jiao, Zong-Ye Li, Fang Liu, Hua Yang, Wen-Xing Li

doi : 10.18632/aging.204022

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Improving ovarian cancer treatment decision using a novel risk predictive tool

Zhenyi Xu, Jiali Song, Lei Cao, Zhiwei Rong, Wenjie Zhang, Jia He, Kang Li, Yan Hou

doi : 10.18632/aging.204023

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Decisive gene strategy on osteoporosis: a comprehensive whole-literature-based approach for conclusive candidate gene targets

Yueh-Chun Chen, Yu-Jui Tsai, Chih-Chien Wang, Pi-Shao Ko, Wen Su, Sui-Lung Su

doi : 10.18632/aging.204026

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NRIP1 aggravates lung injury caused by Pseudomonas aeruginosa in mice by increasing PIAS1 ubiquitination

Miaoyi Huang, Jianying Li, Jie Bai, Xusheng Du, Hua Guo, Bo Wang, Jiru Xu

doi : 10.18632/aging.204027

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MicroRNA-181a-5p prevents the progression of esophageal squamous cell carcinoma in vivo and in vitro via the MEK1-mediated ERK-MMP signaling pathway

Mingbo Wang, Chao Huang, Wenda Gao, Yonggang Zhu, Fan Zhang, Zhenhua Li, Ziqiang Tian

doi : 10.18632/aging.204028

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Claudin-5 relieves cognitive decline in Alzheimer’s disease mice through suppression of inhibitory GABAergic neurotransmission

Ning Zhu, Meidan Wei, Linguang Yuan, Xiaodan He, Chunli Chen, Aimin Ji, Guozeng Zhang

doi : 10.18632/aging.204029

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Effective biomarkers and therapeutic targets of nerve-immunity interaction in the treatment of depression: an integrated investigation of the miRNA-mRNA regulatory networks

Zixuan Wu, Zhixiang Cai, Hongshuo Shi, Xuyan Huang, Minjie Cai, Kai Yuan, Peidong Huang, Guoqi Shi, Tao Yan, Zhichao Li

doi : 10.18632/aging.204030

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Synergistic blocking of RAS downstream signaling and epigenetic pathway in KRAS mutant pancreatic cancer

Xiaofei Zhang, Tiebo Mao, Haiyan Xu, Shumin Li, Ming Yue, Jingyu Ma, Jiayu Yao, Yongchao Wang, Xiao Zhang, Weiyu Ge, Yanling Wang, Daiyuan Shentu, Liwei Wang

doi : 10.18632/aging.204031

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Association of CIDEB gene promoter methylation with overweight or obesity in adults

Zhiguang Ping, Zhaoyan Guo, Ming Lu, Yanzi Chen, Li Liu

doi : 10.18632/aging.204032

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Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling

Bin Zhou, Jing Zhang, Yixuan Chen, Yang Liu, Xiaoyi Tang, Panpan Xia, Peng Yu, Shuchun Yu

doi : 10.18632/aging.204033

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Endothelin-1-mediated miR-let-7g-5p triggers interlukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients with diabetes mellitus

Chung-Huang Tsai, Pei-Ju Huang, IT Lee, Chien-Min Chen, Min Huan Wu

doi : 10.18632/aging.204034

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microRNA-569 inhibits tumor metastasis in pancreatic cancer by directly targeting NUSAP1

Xiaohui Guo, Yatian Li, Xiaofang Che, Kezuo Hou, Xiujuan Qu, Ce Li

doi : 10.18632/aging.204035

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LncRNA136131 suppresses apoptosis of renal tubular epithelial cells in acute kidney injury by targeting the miR-378a-3p/Rab10 axis

Zhifen Wu, Jian Pan, Jurong Yang, Dongshan Zhang

doi : 10.18632/aging.204036

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F12 as a reliable diagnostic and prognostic biomarker associated with immune infiltration in papillary thyroid cancer

Jun-Hua Luo, Xiu-Xia Zhang, Wu-Hui Sun

doi : 10.18632/aging.204037

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Integrative analysis of expression, prognostic significance and immune infiltration of RFC family genes in human sarcoma

Gen Wu, Jian Zhou, Xi Zhu, Xianzhe Tang, Jie Liu, Qiong Zhou, Ziyuan Chen, Tang Liu, Wanchun Wang, Xungang Xiao, Tong Wu

doi : 10.18632/aging.204039

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Correction for: CD36 upregulates DEK transcription and promotes cell migration and invasion via GSK-3β/β-catenin-mediated epithelial-to-mesenchymal transition in gastric cancer

Jin Wang, Ti Wen, Zhi Li, Xiaofang Che, Libao Gong, Zihan Jiao, Xiujuan Qu, Yunpeng Liu

doi : 10.18632/aging.204046

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