Journal of Allergy and Clinical Immunology




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doi : 10.1016/S0091-6749(22)00562-0

Volume 149, Issue 6, June 2022, Page OFC

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Autoimmune chronic spontaneous urticaria

PavelKolkhirMDabc∗MelbaMuñozMD, PhDabd∗RiccardoAseroMDeMartaFerrerMD, PhDfEmekKocatürkMDgMartinMetzMDabYi-KuiXiangMDabMarcusMaurerMDab

doi : 10.1016/j.jaci.2022.04.010

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Autoimmune chronic spontaneous urticaria

doi : 10.1016/j.jaci.2022.04.014

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Selected recent advances in understanding the role of human mast cells in health and disease

FrancescaLevi-SchafferPharmD, PhDaBernhard F.GibbsPhDbJennyHallgrenPhDcCarloPucilloMDdFrankRedegeldPhDeFrankSiebenhaarMDfgJoanaVittePhDhiSorayaMezouarPhDjMoïseMichelPharmDhkPier GiorgioPuzzovioMSaMarcusMaurerMDfg

doi : 10.1016/j.jaci.2022.01.030

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KIT as a master regulator of the mast cell lineage

MindyTsaiDMScaPeterValentMDbcStephen J.GalliMDad

doi : 10.1016/j.jaci.2022.04.012

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Clinical impact and proposed application of molecular markers, genetic variants, and cytogenetic analysis in mast cell neoplasms: Status 2022

MichelArockPharmD, PhDa∗GregorHoermannMD, PhDbc∗KarlSotlarMDdOlivierHermineMD, PhDeWolfgang R.SperrMDbfKarinHartmannMDghKnutBrockowMDiCemAkinMD, PhDjMassimoTriggianiMD, PhDkSigurdBroesby-OlsenMDlAndreasReiterMDmJasonGotlibMD, MSnHans-PeterHornyMDoAlbertoOrfaoMD, PhDpDean D.MetcalfeMDqPeterValentMDbf

doi : 10.1016/j.jaci.2022.04.004

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Drug-induced mast cell eradication: A novel approach to treat mast cell activation disorders?

PeterValentMDabCemAkinMD, PhDcKarinHartmannMDdeAndreasReiterMDfJasonGotlibMD, MSgKarlSotlarMDhWolfgang R.SperrMDabLinaDegenfeld-SchonburgMDabDubravkaSmiljkovicPhDabMassimoTriggianiMD, PhDiHans-PeterHornyMDjMichelArockPharmD, PhDkStephen J.GalliMDlDean D.MetcalfeMD, MSm

doi : 10.1016/j.jaci.2022.04.003

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Neuroimmune communication regulating pruritus in atopic dermatitis

MartinSteinhoffMD, PhDabcdefFareedAhmadPhDbcAtulPandeyPhDbcAngelikiDatsiPhDgAydaAlHammadiMDaSaraAl-KhawagaMD, PhDaAyshaAl-MalkiMDaJianghuiMengPhDhMajidAlamPhDbcJoergBuddenkotteMD, PhDabc

doi : 10.1016/j.jaci.2022.03.010

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The HOME Core outcome set for clinical trials of atopic dermatitis

Hywel C.WilliamsDScaJochenSchmittMDbKim S.ThomasPhDaPhyllis I.SpulsPhDcEric L.SimpsonMDdChristian J.ApfelbacherPhDefJoanne R.ChalmersPhDaMasutakaFuruePhDgNoritoKatohPhDhLouise A.A.GerbensPhDcYael A.LeshemMDijLauraHowellsPhDaJasvinder A.SinghMPHklmMaartenBoersPhDnHOME Initiative

doi : 10.1016/j.jaci.2022.03.017

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Tyrosine kinase inhibitors for the treatment of indolent systemic mastocytosis: Are we there yet?

CemAkinMD, PhDaMichelArockPharm D, PhDbPeterValentMDcd

doi : 10.1016/j.jaci.2022.04.020

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Advances in mast cell biology

Joshua A.BoyceMD

doi : 10.1016/j.jaci.2022.03.029

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In lasting tribute: Dr Thomas Waldmann, September 21, 1930, to September 25, 2021

WarrenStroberMD

doi : 10.1016/j.jaci.2022.03.016

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News Beyond Our Pages

Marc E.RothenbergMD, PhD∗JeanBousquetMD∗

doi : 10.1016/j.jaci.2022.04.015

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TYK-ing all the boxes in psoriasis

ChristophSchlapbachMD, PhDaCurdinConradMDb

doi : 10.1016/j.jaci.2022.03.014

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How are airborne allergens remembered by the immune system?

HirohitoKitaMDab

doi : 10.1016/j.jaci.2022.02.014

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Registries are shaping how we think about primary immunodeficiency diseases

Jordan K.AbbottMDaErwin W.GelfandMDab

doi : 10.1016/j.jaci.2022.04.019

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Preschool wheeze phenotypes from birth cohorts: Where do we go from here?

Jason S.DebleyMD, MPHab

doi : 10.1016/j.jaci.2022.03.013

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Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity

Leanne P.M.van LeeuwenMDab∗Corine H.GeurtsvanKesselMD, PhDa∗‡Pauline M.EllerbroekMD, PhDc‡§Godelieve J.de BreeMD, PhDd‡§JudithPotjewijdMDe‡§AbrahamRutgersMD, PhDf‡§HettyJolinkMD, PhDg‡§Frankvan de VeerdonkMD, PhDh‡§Eric C.M.van GorpMD, PhDabFayede WiltBScaSusanneBogersMScaLennertGommersBScaDarylGeersMScaAnke H.W.BrunsMD, PhDcHelen L.LeavisMD, PhDcJelle W.van HagaBScdBregtje A.LemkesMD, PhDdAnnelouvan der VeenBScd…Virgil A.S.H.DalmMD, PhDjk‡‖

doi : 10.1016/j.jaci.2022.04.002

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The arrival of SARS-CoV-2–neutralizing antibodies in a currently available commercial immunoglobulin

Aaron L.MillerMSabNicholas L.RiderDOcRichard B.PylesPhDabBarbaraJudyPhDdXupingXiePhDePei-YongShiPhDeThomas G.KsiazekDVM, PhDd

doi : 10.1016/j.jaci.2022.03.026

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Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe

Nils O.JõgiMDadNegusseKitabaPhDeTorgeirStoraasMD, PhDdViviSchlünssenMD, PhDfgKaiTriebnerPhDabJohn W.HollowayPhDeWilliam G.C.HorsnellPhDhijCecilieSvanesMD, PhDdcRandi J.BertelsenPhDak

doi : 10.1016/j.jaci.2021.11.013

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Refractory neutrophilic asthma and ciliary genes

Vamsi P.GunturMD, MScabLaurie A.MankaMDabCamille M.MoorePhDcElizabethWynnMSeEszter K.VladarPhDfRafeulAlamMD, PhDbdTuyet-HangPhamMT, MSgTasha E.FingerlinPhDceRichard J.MartinMDab

doi : 10.1016/j.jaci.2021.12.761

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Multiomics analysis identifies BIRC3 as a novel glucocorticoid response–associated gene

MengyuanKanPhDaAvantika R.DiwadkarMSaHaoyueShuaiMSaJaehyunJooPhDaAlberta L.WangMDbcMei-SingOngPhDdJoanne E.SordilloScD, MSdCarlosIribarrenMD, MPH, PhDeMeng X.LuMD, MSeNataliaHernandez-PachecoPhDfgJavierPerez-GarciaPharmDhMarioGorenjakMBI, PhDiUrošPoto�nikPhDijEsteban G.BurchardMD, MPHklMariaPino-YanesPhDghmAnn ChenWuMD, MPHdBlanca E.HimesPhDa

doi : 10.1016/j.jaci.2021.11.025

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A genomic approach identifies sRAGE as a putatively causal protein for asthma

HelenaBuiBAabAmenaKeshawarzPhDabShih-JenHwangPhDabChenYaoPhDabGha YoungLeeBSabcKathrynRectoBSabGeorge T.O’ConnorMDdDanielLevyMDab

doi : 10.1016/j.jaci.2021.11.027

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Mast cells, cortistatin, and its receptor, MRGPRX2, are linked to the pathogenesis of chronic prurigo

PavelKolkhirMDabcPolinaPyatilovaMDabTameemAshryabdQingqingJiaoPhDabeAngela TeresaAbad-PerezaSabineAltrichterMDabfCarolina ElisaVera AyalaMDabMartin K.ChurchPhD, DScabJiajunHeabgKatharinaLohseMDabMartinMetzMDabJörgScheffelPhDabMuratTürkMDhStefanFrischbutterPhDabMarcusMaurerMDab

doi : 10.1016/j.jaci.2022.02.021

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Molecular and clinical effects of selective tyrosine kinase 2 inhibition with deucravacitinib in psoriasis

Ian M.CatlettPhDaYanhuaHuPhDaLuGaoPhDaSubhashisBanerjeeMDaKennethGordonMDbJames G.KruegerMD, PhDc

doi : 10.1016/j.jaci.2021.11.001

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Hsa_circ_0004287 inhibits macrophage-mediated inflammation in an N6-methyladenosine–dependent manner in atopic dermatitis and psoriasis

LanYangBSabJinrongFuMD, PhDacXiaoHanPhDabCaiyanZhangPhDadLiXiaMSabRonghuiZhuBSeSaihuaHuangMSabWenfengXiaoBSabHongmiaoYuMSabYajingGaoBSabQiuyanLiangMSabWeiLiMD, PhDeYufengZhouMD, PhDab

doi : 10.1016/j.jaci.2021.11.024

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KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results

AndreasMaetzelMD, MSc, PhDabMichael D.SmithPharmDaEdward J.DuckworthBScaSally L.HamptonBScaGian MarcoDe DonatisPhDaNivethaMurugesanPhDaLouise J.RushbrookeBScaLilyLiMSaDanielleFrancombePhDcEdward P.FeenerPhDaChristopher M.YeaPhDa

doi : 10.1016/j.jaci.2021.10.038

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Safety of peanut (Arachis hypogaea) allergen powder-dnfp in children and teenagers with peanut allergy: Pooled summary of phase 3 and extension trials

Kari R.BrownMD, MScaJamesBakerMDbAndreaVeredaMD, PhDcKirstenBeyerMDdA. WesleyBurksMDeGeorgedu ToitMB, BChfJonathanO’B HourihaneMDgStacie M.JonesMDhDavidNorvalBSccAdrianDanaMDaWayneShrefflerMD, PhDiBrian P.VickeryMDjThomasCasaleMDkBenSkeelMSccDanielAdelmanMDal

doi : 10.1016/j.jaci.2021.12.780

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Mast cells instruct keratinocytes to produce thymic stromal lymphopoietin: Relevance of the tryptase/protease-activated receptor 2 axis

DavenderRedhuPhDaKristinFrankePhDaMarinaAparicio-SotoPhDaVandanaKumariPhDaKristijanPazurPhDaAnjaIllerhausPhDbKarinHartmannMDcdMargittaWormMDaMagdaBabinaPhDa

doi : 10.1016/j.jaci.2022.01.029

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Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission

NetaliBen-Baruch MorgensternPhDaAdina Y.BallabanBSaTingWenMD, PhDa∗TetsuoShodaMD, PhDaJulie M.CaldwellPhDaKaraKliewerPhD, RDaJennifer M.FeltonPhDaJ. PabloAboniaMDaVincent A.MukkadaMDbcPhilip E.PutnamMDbcScott M.BoltonMDbcDaniel F.DwyerPhDde‡Nora A.BarrettMDde‡Marc E.RothenbergMD, PhDab‡

doi : 10.1016/j.jaci.2022.02.025

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Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma

AntonieLechnerPhDaFiona D.R.HenkelMSca∗FranziskaHartungMSca∗SinaBohnackerMScaFrancescaAlessandriniPhDaEkaterina O.GubernatorovaMScbMarina S.DrutskayaPhDbCarloAngioniBSccYannickSchreiberBScdPascalHaimerlPhDaYanGePhDeDominiqueThomasPhDcAgnieszka M.KabatPhDfEdward J.PearcePhDfCasparOhnmachtPhDaSergei A.NedospasovPhDbPeter J.MurrayPhDgAdam M.ChakerMDah…JuliaEsser-von BierenPhDa

doi : 10.1016/j.jaci.2021.11.026

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A mitochondrial STAT3-methionine metabolism axis promotes ILC2-driven allergic lung inflammation

LiuhuiFuPhDabcJieZhaoBSabcJiaoyanHuangPhDabcNaLiBSabcXinDongMSabcYaoHePhDabcWenyanWangPhDabcYuWangPhDdJuQiuPhDeXiaohuanGuoPhDabc

doi : 10.1016/j.jaci.2021.12.783

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Airway inflammation and dysbiosis in antibody deficiency despite the presence of IgG

AnnaSchnellPhDabMehmetDavrandiPhDcdMoritzSaxenhoferPhDabClaraLeboreiroBSccdStefanieGraeterPhDabFernandoMoreiraBSceMariaHauswaldPhDabCarolinWittePhDabIrinaIrincheevaPhDabAnnetteFeussnerPhDabCedricVonarburgPhDabIlkaSchulzeMD, PhDabAlexanderSchaubPhDabSiobhan O.BurnsPhDceDavid M.LoweFRCP, PhDce

doi : 10.1016/j.jaci.2021.12.778

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An appraisal of the frequency and severity of noninfectious manifestations in primary immunodeficiencies: A study of a national retrospective cohort of 1375 patients over 10 years

MickaëlAlligonBSaNizarMahlaouiMD, PhDabVirginieCourteilleBSaLaurenceCostesBSaVeronicaAfonsoBSaPhilippeRandrianomenjanaharyBSaNathaliede VergnesBSaAnjaRanohavimparanyBSaDuyVoBSaInèsHafsaBSaPerrineBachBSaVincentBenoitPhDcNicolasGarcelonPhDcAlainFischerMD, PhDabde

doi : 10.1016/j.jaci.2021.12.790

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Altered secretome by diesel exhaust particles and lipopolysaccharide in primary human nasal epithelium

NahyunKimPhDaDohyunHanPhDbInjae JosephWangMSbDoo HeeHanMD, PhDcMyung-WhanSuhMD, PhDcdJun HoLeeMD, PhDcdSeung-HaOhMD, PhDcdMoo KyunParkMD, PhDcd

doi : 10.1016/j.jaci.2021.12.793

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Helminth infections and allergic diseases: Systematic review and meta-analysis of the global literature

MargareteArraisMD, PhDabcTiagoMaricotoMD, PhDcdeBright I.NwaruPhDfPhilip J.CooperPhDghJorge M.R.GamaPhDciMiguelBritoPhDbjLuisTaborda-BarataMD, PhDckl

doi : 10.1016/j.jaci.2021.12.777

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Wheeze trajectories: Determinants and outcomes in the CHILD Cohort Study

RuixueDaiMSca∗KozetaMilikuMD, PhDa∗SirishaGaddipatiBSccJihoonChoiPhDdAmirthagowriAmbalavananPhDdMaxwell M.TranBHScaMyrthaReynaMScaHindSbihiPhDeWendyLouPhDfPaulaParvulescuMD, MScgDiana L.LefebvrePhDbAllan B.BeckerMDhMeghan B.AzadPhDhPiush J.MandhaneMD, PhDiStuart E.TurveyMBBS, DPhileQinglingDuanPhDdTheo J.MoraesMD, PhDaMalcolm R.SearsMBChBbPadmajaSubbaraoMD, MScab

doi : 10.1016/j.jaci.2021.10.039

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Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy

R. SharonChinthrajahMDaStacie M.JonesMDbEdwin H.KimMDcScott H.SichererMDdWayneShrefflerMD, PhDeBruce J.LanserMD, MPHfNeginAtriMPHgDenise C.BabineauPhDhDaniel C.AdelmanMDiAhmarIqbalMDjSusan L.LimbMDkAmanda K.Rudman SpergelMDgAlkisTogiasMDgRobert A.WoodMDl

doi : 10.1016/j.jaci.2021.12.789

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Disease-associated mutations in topoisomerase IIβ result in defective NK cells

LoriBroderickMD, PhDabGwendolyn M.ClayMD, PhDaRobert H.BlumBScYangLiuPhDdRachaelMcVicarBSdFabioPapesPhDaLaela M.BooshehriMSaIan G.CowellPhDeCaroline A.AustinPhDeChristopher D.PutnamPhDcfDan S.KaufmanMD, PhDc

doi : 10.1016/j.jaci.2021.12.792

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Reply

WilliamHardieMDCarolyn M.KercsmarMS, MD

doi : 10.1016/j.jaci.2022.03.004

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