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Diverse immune mechanisms of allergen immunotherapy for allergic rhinitis with and without asthma
Mohamed H.ShamjiPhD, FAAAAIabHanisahSharifPhDabJanice A.LayhadiPhDabRongfeiZhuPhDabcUdayKishorePhDdHaraldRenzMDe
Allergen immunotherapy for long-term tolerance and prevention
MartinPenagosMD, MScStephen R.DurhamMD, FRCP
A regulator’s view on AIT clinical trials in the United States and Europe: Why successful studies fail to support licensure
AndreasBonertzPhDa∗AnubhaTripathiMDb∗JuliaZimmerPhDaChristinaReebPhDaSusanneKaulDVMaJenniferBridgewaterMPHbRonald L.RabinMDbJay E.SlaterMDbStefanViethsPhDa
Pathogenic insights from genetic causes of autoinflammatory inflammasomopathies and interferonopathies
BinLinPhDRaphaelaGoldbach-ManskyMD, MHS
Which patients with asthma are most likely to benefit from allergen immunotherapy?
Frédéricde BlayMDabcAlinaGherasimMDbTomas B.CasaleMDdVirginieDoyenMDaeDavidBernsteinMDf
Impressions and aspirations from the FDA GREAT VI Workshop on Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis and Perspectives for Progress in the Field
Marc E.RothenbergMD, PhDabShawna K.B.HottingerMS, ELSaNirmalaGonsalvesMDcGlenn T.FurutaMDdMargaret H.CollinsMDeNicholas J.TalleyAC, MD, PhDfKathrynPetersonMD, MScigCaliesMenard-KatcherMD, MScsdMacieSmithhIkuoHiranoMDcRobert M.GentaMDiMirnaChehadeMD, MPHjSandeep K.GuptaMDkJonathan M.SpergelMD, PhDlSeema S.AcevesMD, PhDm∗Evan S.DellonMD, MPHn∗
Advances in chronic rhinosinusitis in 2020 and 2021
ZhaofengXuMDab∗YanranHuangMDac∗TimDelemarrea∗CarloCavaliereMD, PhDd∗NanZhangMD, PhDaClausBachertMD, PhDabe
Real-world evidence: Methods for assessing long-term health and effectiveness of allergy immunotherapy
BenediktFritzschingMD, Prof (apl) DraMarcoContoliMD, PhDbCelestePorsbjergMD, PhDcSarahBuchsMScdJulie RaskLarsenMD, PhDdNickFreemantlePhDe
Managing risk of anaphylaxis in patients receiving allergen immunotherapy: Assessing benefit versus risk
David I.BernsteinMDTolly G.EpsteinMD, MS
Toward explaining fixed airflow obstruction in asthma
SandraRuttingPhDabKatrina O.TongaMBChB, PhDabcdeGregory G.KingMBChB, PhDabc
Bacterial lysates to inhibit allergic airway disease: Are they up to the challenge?
ChristianTaubeMD
Biologics for chronic rhinosinusitis with nasal polyps (CRSwNP)
Glenis K.ScaddingMD, FRCPaGuy W.ScaddingPhD, FRCPb
Role of nasal microbiota and host response in infants with respiratory syncytial virus infection: Causal questions about respiratory outcomes
KoheiHasegawaMD, MPH, MSabCarlos A.CamargoJr.MD, DrPH, FAAAAIabJonathan M.MansbachMD, MPHbc
In vitro models of human mast cells: How to get more and better with induced pluripotent stem cells?
LaurentL'hommePhDaDavidDombrowiczPhDa
Immunogenicity and tolerability of COVID-19 messenger RNA vaccines in primary immunodeficiency patients with functional B-cell defects
Michele N.PhamMDaKanagavelMurugesanPhDbNiazBanaeiMDbceBenjamin A.PinskyMD, PhDbcfMonicaTangMDaElisabethHoyteNPdDavid B.LewisMDdYaelGernezMD, PhDd
Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndrome
Janice J.HuangBEaSamantha B.GainesBAbMateo L.AmezcuaBAaTamar R.LubellMDcPeter S.DayanMD, MSccMarissaDaleMDdAlexis D.BoneparthMDaMark D.HicarMD PhDeRobertWinchesterMDbMarkGorelikMDa
The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression
VadimPivnioukPhDabcOksanaPivnioukMAbAveryDeVriesPhDbcJennifer L.UhrlaubMSdAshleyMichaelBSbDenisPivnioukBSâ–ªSydney R.VanLindenBSbMichelle Y.ConwayBSeSeongminHahnMSbSean P.MalonebPeaceEzehPhDbJared M.ChurkoPhDacDaynaAndersonBSbMonicaKraftMDceJankoNikolich-ZugichMD, PhDcdDonataVercelliMDabcf
Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory
KaorukoShimizuMD, PhDaNaoyaTanabeMD, PhDbAkiraOgumaMDaHirokazuKimuraMD, PhDaMasaruSuzukiMD, PhDaIsaoYokotaPhD, MPHcHironiMakitaMD, PhDadSusumuSatoMD, PhDbToyohiroHiraiMD, PhDbMasaharuNishimuraMD, PhDadSatoshiKonnoMD, PhDaHi-CARAT Investigators
Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis
VadimPivnioukPhDabcJoao A.Gimenes-JuniorPhDb∗PeaceEzehPhDb∗AshleyMichaelBSbOksanaPivnioukMAbSeongminHahnMSbSydney R.VanLindenBSbSean P.MalonebAmirAbidovMDdDaynaAndersonBSbJustynaGozdzPhDbAveryDeVriesPhDbcFernando D.MartinezMDbcChristianPasqualiPhDfDonataVercelliMDabce
Long-term efficacy and safety of omalizumab for nasal polyposis in an open-label extension study
PhilippeGevaertMD, PhDaRebeccaSaenzMD, PhDbJonathanCorrenMDcJoseph K.HanMDdJoaquimMullolMD, PhDeStella E.LeeMDfRandall A.OwMDgRuiZhaoPhDbMonetHowardMSchKitWongPhDbLutafIslamDVM, MSciMonicaLigueros-SaylanMDjTheodore A.OmachiMDbClausBachertMD, PhDakl
Upper respiratory tract bacterial-immune interactions during respiratory syncytial virus infection in infancy
ChristianRosas-SalazarMD, MPHa∗Zheng-ZhengTangPhDb∗Meghan H.ShiltsMS, MHScKedir N.TuriPhDdQilinHongMSbDerek A.WigginsMSdChristian E.LynchMPHdTebebGebretsadikMPHeJames D.ChappellMD, PhDfR. StokesPeeblesJr.MDdLarry J.AndersonMDgSuman R.DasPhDchTina V.HartertMD, MPHd
Upadacitinib plus topical corticosteroids in atopic dermatitis: Week 52 AD Up study results
Jonathan I.SilverbergMDaMarjoleinde Bruin-WellerMDbThomasBieberMDcWeilySoongMDdKenjiKabashimaMDeAntonioCostanzoMDfDavidRosmarinMDgCharlesLyndeMDhJohnLiuMDiAmyGamelliPhDiJieweiZengPhDiBarryLadizinskiMDiAlvina D.ChuMDiKristianReichMDj
A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci
XiaoChangPhDaMichaelMarchPhDaFrankMentchPhDaKennyNguyenPhDaJosephGlessnerPhDaHuiqiQuPhDaYichuanLiuPhDaGlenFurutaMDbcSeemaAcevesMD, PhDdeNirmalaGonsalvesMDfKariNadeauMD, PhDgAntonellaCianferoniMD, PhDhiJonathanSpergelMD, PhDhiPatrickSleimanPhDahjHakonHakonarsonMD, PhDahjk
Anaphylaxis knowledge gaps and future research priorities: AÂ consensus report
Timothy E.DribinMDaDavidSchnadowerMD, MPHaJulieWangMDbCarlos A.CamargoJrMD, DrPHcKenneth A.MichelsonMD, MPHdMarcusShakerMD, MSceSusan A.RuddersMD, MSfDavidVylesDO, MSgDavid B.K.GoldenMDhJonathan M.SpergelMD, PhDiRonna L.CampbellMD, PhDjMark I.NeumanMD, MPHdPeter S.CapucilliMDkMichaelPistinerMD, MMSclMarianaCastellsMD, PhDmJuheeLeeMDiDavid C.BrousseauMD, MSgLynda C.SchneiderMDf…Hugh A.SampsonMDb
Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis
AllysonMatejaMSPHaQinluWangMSbJackChovanecBScJiwonKimBScKenneth J.WilsonPhDdLawrence B.SchwartzMD, PhDeSarah C.GloverDOdfMelody C.CarterMDcDean D.MetcalfeMDcEricaBrittainPhDgJonathan J.LyonsMDc
A novel functional mast cell assay for the detection of allergies
NoemiZbärenMScabDanielBriggerPhDabDanielBachmannMSccArthurHelblingMDdLukasJörgMDdMichael P.HornPhDeJohannes M.SchmidMDfHans JürgenHoffmannPhDfJean-PierreKinetMDgThomasKaufmannPhDc∗AlexanderEggelPhDab∗
IgE recognition of the house dust mite allergen Der p 37 is associated with asthma
Huey-JyHuangPhDaYvonneResch-MaratPhDaAnneCassetPhDaMargitWeghoferPhDaPetraZieglmayerMDbiRenéZieglmayerDIbPatrickLemellPhDbFriedrichHorakMDcKuan-WeiChenPhDaEkaterinaPotapovaMScdPaolo M.MatricardiMDdGabriellePauliMDeMonikaGrotePhDfRudolfValentaMDaghiSusanneVrtalaPhDa
TLR3-driven IFN-β antagonizes STAT5-activating cytokines and suppresses innate type 2 response in the lung
RinnaTeiMDabKojiIijimaPhDaKojiMatsumotoMDaTakaoKobayashiPhDaJyotiLamaBAcElizabeth A.JacobsenPhDadHirohitoKitaMDad
A novel approach for studying mast cell–driven disorders: Mast cells derived from induced pluripotent stem cells
YanyanLuoaeValeriaFernandez VallonePhDbJiajunHeaceStefanFrischbutterPhDaePavelKolkhirMDadeSherezadeMoñino-RomeroPhDaeHaraldStachelscheidPhDbViktoriaStreu-HaddadaeMarcusMaurerMDaeFrankSiebenhaarMDae∗JörgScheffelPhDae∗
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
MinghuiHePhDaMezida B.SaeedPhDaJulienRecordPhDaMartonKeszeiPhDaLiaGonçalves PinhoMScabLarissaVasconcelos-FontesPhDabRobertaD’AulerioMScaRhaissaVieiraPhDaMariana M.S.OliveiraMScaChiaraGeyerMScaLenaBohaumilitzkyMScaMeikeThiemannMScaEkaterinaDeordievaPhDcLieselotBuedtsPhDdJoao PedroMatias LopesMScefDmitryPershinPhDcLennartHammarströmMD, PhDgYuXiaMDh…Lisa S.WesterbergPhDl
Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV
ErikoKomiyaPhDaMitsutoshiTominagaPhDabRyoHatanoPhDcYujiKamikuboPhDdSumikaToyamaPhDaHakushunSakairiMD, PhDdKotaroHondaPhDaTakumiItohPhDceYayoiKamataPhDabMunehiroTsurumachiMDafRyomaKishiMDafKeiOhnumaMD, PhDcTakashiSakuraiMD, PhDdChikaoMorimotoMD, PhDcKenjiTakamoriMD, PhDabf
Comparison of hematopoietic cell transplant conditioning regimens for hemophagocytic lymphohistiocytosis disorders
Rebecca A.MarshMDaKyleHebertMSbSoyoungKimPhDbChristopher C.DvorakMDcVictor M.AquinoMDdK. ScottBakerMD, MSeDeepakChellapandianMDfBlachyDávila SaldañaMDgChristine N.DuncanMDhMichael J.EckrichMD, MPHiGeorge E.GeorgesMDeTimothy S.OlsonMD, PhDjMichael A.PulsipherMDkShaliniShenoyMDlElizabethStengerMDmMark VanderLugtMDnLolie C.YuMDoAndrew R.GenneryMDpMaryEapenMBBS, MSb
Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis
EevaSlizPhDabLauraHuilajaMD, PhDcdAnuPasanenPhDcdefTriinLaiskPhDgEneReimannPhDgReedikMägiPhDgFinnGen∗Estonian Biobank Research Team‡KatariinaHannula-JouppiMD, PhDhijkSirkkuPeltonenMD, PhDlmnoTeeaSalmiMD, PhDpqLeenaKouluMD, PhDlmKaisaTasanenMD, PhDcd§JohannesKettunenPhDab§
Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution
Ottavia M.DelmonteMD, PhDaRiccardoCastagnoliMDaJasonYuPhDbcdChristopher C.DvorakMDbdMorton J.CowanMDbcdBlachy J.Dávila SaldañaMDeSuk SeeDe RavinMD, PhDaEwelinaMamcarzMDfCatherine K.ChangBSbdStephen R.DaleyPhDgLinda M.GriffithMD, MHS, PhDhLuigi D.NotarangeloMDa∗Jennifer M.PuckMDbcd∗
Hematopoietic stem cell transplantation in a patient with proteasome-associated autoinflammatory syndrome (PRAAS)
DoritVerhoevenMDabDienekeSchonenberg-MeinemaMDaFrédéricEbsteinPhDcJonas J.PapendorfMSccPaul A.BaarsPhDbEster M.M.van LeeuwenPhDbMachiel H.JansenBScbArjan C.LankesterMD, PhDdMirjamvan der BurgPhDeSandrineFlorquinMD, PhDfSaskia M.MaasMDgSilvanavan KoningsbruggenPhDgElkeKrügerPhDcJ. Merlijnvan den BergMD, PhDaTaco W.KuijpersMD, PhDab
Life-threatening anaphylaxis to peanut — impossible to predict?
Paul J.TurnerFRCPCH, PhDAdnanCustovicMD, PhD, FMedSci
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Alexandra F.SantosMD, PhDabcdEthanEvanseColinO'RourkeMSeHenry T.BahnsonMPHefGideonLackMBBS, FRCPCHabcd
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MingzhuJinMDabSimonWatkinsPhDcYolandaLarribaPhDdCallenWallacePhDcClaudette St.CroixPhDcXiuxiaZhouPhDaJinmingZhaoPhDaShyamalPeddadaPhDeSally E.WenzelMDaf
