Journal of Ethnopharmacology




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Editorial Board

doi : 10.1016/S0378-8741(22)00336-1

Volume 292, 28 June 2022, 115297

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Ethnobotany, phytochemistry, pharmacology, and toxicology of the genus Sambucus L. (Viburnaceae)

Emmanuel NyongesaWaswaabc1JingLiabc1Elijah MbandiMkalaabcVincent OkeloWangaabcElizabeth SyowaiMutindaabcConsolataNanjalaabcWyclif OchiengOdagoabcDaniel MutaviKatumoabcMoses KiregaGichuadRobert WahitiGiturudGuang-WanHuabcQing-FengWangabc

doi : 10.1016/j.jep.2022.115102

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Insights to the tribe Haemantheae of the South African Amaryllidaceae

Jerald J.NairJohannesvan Staden

doi : 10.1016/j.jep.2022.115177

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Ethnobotanical, pharmacological, phytochemical, and clinical investigations on Moroccan medicinal plants traditionally used for the management of renal dysfunctions

BencheikhNoureddineaElachouriMostafaaSubhash C.Mandalb

doi : 10.1016/j.jep.2022.115178

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Aconitum pendulum and Aconitum flavum: A narrative review on traditional uses, phytochemistry, bioactivities and processing methods

Cong-YingLiaZhenZhouaTongXuaNai-YuWangbCeTangaXiao-YanTanbZi-GeFengaYiZhangaYueLiua

doi : 10.1016/j.jep.2022.115216

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Pharmacological re-assessment of traditional medicinal plants-derived inhibitors as antidotes against snakebite envenoming: A critical review

UpasanaPuzariaPedro AlexandrinoFernandesbAshis K.Mukherjeeac

doi : 10.1016/j.jep.2022.115208

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Clinical features of adverse events associated with Xiyanping-Ribavirin combination: A systematic review

RuiZhenga1YangSuna1XiaoyuZhangaChenZhaobPengqianWangcShiqiChenaZhaoChenaRuijinQiuaAihuaLiangcHongcaiShanga

doi : 10.1016/j.jep.2022.115076

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Comparative effectiveness of phlegm-heat clearing Chinese medicine injections for AECOPD: A systematic review and network meta-analysis

XueyinChenaFuqinKangbJiaqiLaiaXueyiDengcXinfengGuoaShaonanLiua

doi : 10.1016/j.jep.2022.115043

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Identification and action mechanism of lipid regulating components from Rhei Radix et rhizoma

YudongWangaJianingZhangaZhengXuaGuifangZhangaHuijuanLvaXinbenWangbGuijingXubXuefengLiaZhigangYangaHaoliangWangcYongfuWangcHongfangLidYanbinShia

doi : 10.1016/j.jep.2022.115179

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The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation

PengXiaYujiNiubYaruZhangbWenwenLibFanGaobWenwenGubFuguangKuibZhongqiuLiuaLinlinLuaGangjunDub

doi : 10.1016/j.jep.2022.115138

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Analgesic and neuroprotective effects of Baimai Ointment on diabetic peripheral neuropathy

ZhanyiLiab1WenWangab1FengpingMengabZhuqingZhouabZhongqiuZhaocdZhinanMeiab

doi : 10.1016/j.jep.2022.115122

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The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against renal injury and inflammation in mice with diabetic kidney disease

Yi-QiYang1Hai-BoTan1Xiao-YuZhangYu-ZhenZhangQuan-YouLinMin-YiHuangZi-YangLinJia-ZhiMoYueZhangTianLanWei-JianBeiJiaoGuo

doi : 10.1016/j.jep.2022.115165

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Polynesian medicine used to treat diarrhea and ciguatera: An ethnobotanical survey in six islands from French Polynesia

FrançoisChassagneabJean-FrançoisButaudcFrédéricTorrentebEricContebRaimanaHodPhilaRaharivelomananad

doi : 10.1016/j.jep.2022.115186

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Anthelmintic and antimycobacterial activity of fractions and compounds isolated from Cissampelos mucronata

R.T.AkandeabG.FouchecI.M.FamuyideaF.N.MakhubuaS.M.NkadimengaA.O.ArodP.N.Kayoka-KabongodL.J.McGawa

doi : 10.1016/j.jep.2022.115130

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Antioxidant and anti-aging effects of Warburgia salutaris bark aqueous extract: Evidences from in silico, in vitro and in vivo studies

Mohamed A.O.AbdelfattahaMalakDmiriehbWidadBen BakrimcdOmarMouhtadyaMosad A.GhareebeMichaelWinkbMansourSobehc

doi : 10.1016/j.jep.2022.115187

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Gastroprotective effect of hydroalcoholic extract from Agaricus blazei Murill against ethanol-induced gastric ulcer in mice

João FranciscoCâmara NetoaMatheus da SilvaCampeloaGilberto SantosCerqueirabJoão Antônio Lealde MirandabJhonyson Arruda CarvalhoGuedescRaimundo Rafaelde AlmeidaaSandra de AguiarSoaresaNilce VianaGramosaaGuilherme JuliãoZocoloc�caro Gusmão PintoVieiradNágila Maria Pontes SilvaRicardoaMaria Elenir Nobre PinhoRibeiroa

doi : 10.1016/j.jep.2022.115191

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Oridonin attenuates hind limb ischemia–reperfusion injury by modulating Nrf2-mediated oxidative stress and NLRP3-mediated inflammation

XiaoqiZhaoa1YutongLiub1LeiWangaChaolongYancHanLiuaWenxinZhangbHongtingZhaobChenChengbZhipengChenaTianzeXuaKuanyuLibJingCaiaTongQiaoa

doi : 10.1016/j.jep.2022.115206

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Oral administration of processed Cassia obtusifolia L. seed powder May reduce body weight and cholesterol in overweight patients with schizophrenia: A 36-week randomized, double-blind, controlled trial of high and low doses

Ju-YingLeeaWen-LingLiaoabYu-HueiLiuaChao-LinKuocFor-WeyLungdhijChing-LiangHsiehefg

doi : 10.1016/j.jep.2022.115111

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Lingguizhugan decoction protects PC12 cells against Aβ25-35-induced oxidative stress and neuroinflammation by modulating NF-κB/MAPK signaling pathways

JingHan1HaotianZhang1YuZhangZanZhangMaomaoYuSijieWangFeiHan

doi : 10.1016/j.jep.2022.115194

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Aronia melanocarpa (Michx.) Elliott. attenuates dextran sulfate sodium-induced Inflammatory Bowel Disease via regulation of inflammation-related signaling pathways and modulation of the gut microbiota

YutingLia1Ivan StèveNguepi Tsopmejioab1ZipengDiaoaHuanweiXiaoaXueqiWangaZhouyuJinaHuiSongac

doi : 10.1016/j.jep.2022.115190

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Anti-influenza mechanism of phenolic phytochemicals from Canarium album (Lour.) DC. leaf extract

MengjieXiaoaBobbyLim-Ho KongaYahuiZhangcYinhuaYangeJiaqiLuaHung-KayLeedFeiCaocPang-ChuiShawabf

doi : 10.1016/j.jep.2022.115175

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Exploring Vaccinium vitis-idaea L. as a potential source of therapeutic agents: antimicrobial, antioxidant, and anti-inflammatory activities of extracts and fractions

GabrieleVilkickyteaVilmaPetrikaitebAudriusPukalskascAusraSipailienecLinaRaudonead

doi : 10.1016/j.jep.2022.115207

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Total flavonoids of sea buckthorn (Hippophae rhamnoides L.) improve MC903-induced atopic dermatitis-like lesions

YajingGua1XinxinWangbc1FangLiud1JinZhangaXiufangZhangeJipingLiufSijiaLicDechengWanggHongquanGuancDiandongHouac

doi : 10.1016/j.jep.2022.115195

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Cardioprotective effect of ethanol extracts of Sugemule-3 decoction on isoproterenol-induced heart failure in Wistar rats through regulation of mitochondrial dynamics

DongZhenabRi-songNaaYuWangabXueBaiabDan-niFuabCheng-xiWeiabMing-jieLiuabLi-junYuab

doi : 10.1016/j.jep.2021.114669

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Screening bioactive compounds from Danggui-shaoyao-san for treating sodium retention in nephrotic syndrome using bio-affinity ultrafiltration

MoYangabLianghouNicYunlaiWangcdZihuaXuancHuanWuabdWenjingZhaneXinyuWanfJinghuiWangfFanXucd

doi : 10.1016/j.jep.2022.115171

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Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity

Yi-niCaoabc1Shan-shanYueabcd1An-yiWangabc1LuXuabcYi-tongHuabcXueQiaoeTung-YingWufMinYeeYang-ChangWugRongQiabcd

doi : 10.1016/j.jep.2022.115146

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Bioavailability, anti-inflammatory and anti-arthritic effect of Acetyl Keto Boswellic acid and its combination with methotrexate in an arthritic animal model

DavidBanjiaOtilia J.F.BanjibShaikRashidacSaeedAlshahraniaSaad S.Alqahtanib

doi : 10.1016/j.jep.2022.115200

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Antinociceptive, anti-inflammatory and antioxidant activities of the crude ethanolic extract and alkaloid fraction of Waltheria viscosissima A. St. - Hil. (Malvaceae)

ClaudeniseCaldas da Silva Dantas ViegasaAlexandreSérgio SilvabRenanMarinho BragaaHumberto HugoNunes de AndradeaAline KelyFelício de Sousa SantosaMaria DeniseLeite FerreiracMateus DuarteRibeirobLuiz HenriqueAgra Cavalcante SilvadLoianeAlves de LimaeReinaldoNobrega de AlmeidaaMaria de FátimaVanderlei de SouzacTemilceSimões de Assis Cantalicea

doi : 10.1016/j.jep.2022.115173

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Anti-respiratory syncytial virus and anti-herpes simplex virus activity of six Tanzanian medicinal plants with extended studies of Erythrina abyssinica stem bark

Jackson T.MollelabcJoanna S.SaidaRose J.MasalubCharlesHannounaMourice V.N.MbundecRamadhani S.O.NondocTomasBergströmaEdwardTrybalaa

doi : 10.1016/j.jep.2022.115204

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Preventive effect of Atractylodis Rhizoma extract on DSS-induced acute ulcerative colitis through the regulation of the MAPK/NF-κB signals in vivo and in vitro

XiongLina1XiuliGuoa1LinghangQuaJiyuanTuaShuiqingLiabGuoshengCaoabYanjuLiuab

doi : 10.1016/j.jep.2022.115211

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Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes

YixiYangabc1YujinZhangabc1XunChenabcZhouSuabdYuDengabeQiZhaoabc

doi : 10.1016/j.jep.2022.115124

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A network pharmacology-based study on the quality control markers of antithrombotic herbs: Using Salvia miltiorrhiza - Ligusticum chuanxiong as an example

Dai-YanZhanga1Ruo-QianPenga1XuWangeHua-LiZuocdLi-YangLyuaFeng-QingYangeYuan-JiaHuab

doi : 10.1016/j.jep.2022.115197

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Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism

ShihuiYuab1LeGuoac1BoYanabQiangYuanaLetianShanbcLiZhoubcThomasEfferthd

doi : 10.1016/j.jep.2022.115214

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Bushen Jieyu Tiaochong Formula reduces apoptosis of granulosa cells via the PERK-ATF4-CHOP signaling pathway in a rat model of polycystic ovary syndrome with chronic stress

XuePanaYanfengLiubLiuqingLiubBoPangcZhidiSunbSiqiGuandQingyaYanbTingtingMobRanChenbMengbaiXubZhuoChangeXuemingZhoue

doi : 10.1016/j.jep.2021.114923

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Anti-inflammatory properties of Neowerdermannia vorwerkii Fri� ‘Achacana’ used in treating stomach-related ailments

LuisApaza Ticonaab�ngelRumbero SánchezbMarcosHumanes BastantebAndreea MadalinaSerbancMaría J.Hernáiza

doi : 10.1016/j.jep.2022.115198

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Huang Bai Jian Pi decoction alleviates diarrhea and represses inflammatory injury via PI3K/Akt/NF-κB pathway: In vivo and in vitro studies

ZunxiangYanabKaiZhangaKangZhangaGuiboWangaLeiWangaJingyanZhangaZhengyingQiuaZhitingGuoaYandongKangaXiaopingSongbJianxiLia

doi : 10.1016/j.jep.2022.115212

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Centipeda minima: An update on its phytochemistry, pharmacology and safety

JinchengTanaZhipingQiaoaMingjingMengaFanZhangaHiu YeeKwanbKeyingZhongaChunfangYangaYechunWangaMiZhangaZhongqiuLiuacTaoSuacd

doi : 10.1016/j.jep.2022.115027

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Combination of mulberry leaf active components possessed synergetic effect on SD rats with diabetic nephropathy by mediating metabolism, Wnt/β-catenin and TGF-β/Smads signaling pathway

TaoJiaJuanWangaZhuoXubHong-DieCaiabShu-lanSubXinPengcHong-ShengRuana

doi : 10.1016/j.jep.2022.115026

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Metabolomics and integrated network pharmacology analysis reveal attenuates cardiac hypertrophic mechanisms of HuoXin pill

Zhan-WangGaoa1XinZhanga1Qing-YuanZhuoaMei-XianChenaChongYangaZhao-JieChenaYingChenaYi-qiuLiaobcLing-LiWanga

doi : 10.1016/j.jep.2022.115150

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The Chinese medicine babaodan suppresses LPS-induced sepsis by inhibiting NLRP3-mediated inflammasome activation

Yu-feiLiaHong-daShengaJingQianabYiWangabcd

doi : 10.1016/j.jep.2022.115205

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Baihe Dihuang (Lilium Henryi Baker and Rehmannia Glutinosa) decoction attenuates somatostatin interneurons deficits in prefrontal cortex of depression via miRNA-144–3p mediated GABA synthesis and release

XiaoyanXuea1JinPana1HongxiuZhangab1YantingLua1QianchengMaoaKeMaa

doi : 10.1016/j.jep.2022.115218

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Huang-Lian-Jie-Du decoction attenuates cognitive dysfunction of rats with type 2 diabetes by regulating autophagy and NLRP3 inflammasome activation

RuiminTianadXianfengLiuaLijiaJingaLuyangaNaXieaYaHoubHonglinTaoaYiwenTaoaJiasiWucXianliMengab

doi : 10.1016/j.jep.2022.115196

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Nephroprotective mechanisms of Ambrette (Abelmoschus moschatus Medik.) leaf extracts in adriamycin mediated acute kidney injury model of Wistar rats

Sachinthi S.AmarasiriaAnoja P.AttanayakebLakmini K.B.MudduwacKamani A.P.W.Jayatilakab

doi : 10.1016/j.jep.2022.115221

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Herbo-metallic ethnomedicine ‘Malla Sindoor’ ameliorates lung inflammation in murine model of allergic asthma by modulating cytokines status and oxidative stress

AcharyaBalkrishnaabcSiva KumarSolletia1HoshiyarSingha1RaniSinghaKunalBhattacharyaaAnuragVarshneyabd

doi : 10.1016/j.jep.2022.115120

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Garlic (Allium sativum Linnaeus) improved inflammation and reduced cryptosporidiosis burden in immunocompromised mice

AlyaaFaridaMonaYousryaGehanSafwatb

doi : 10.1016/j.jep.2022.115174

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Shuxuetong injection and its peptides enhance angiogenesis after hindlimb ischemia by activating the MYPT1/LIMK1/Cofilin pathway

WeiSunabcd1LushaZhangabcd1ZhiruiFangabc1LifengHanabcQianyiWangabcYuzeLengabcdMengyaoLiabcdYuejinXueabcdYongshengWufZhenguoLifHongWangabcdLuChenabce

doi : 10.1016/j.jep.2022.115166

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Anti-inflammatory and anti-apoptotic effects of Shaoyao decoction on X-ray radiation-induced enteritis of C57BL/6 mice

ZhuohongLia1YingGaoa1LeiDuaYeYuanaWenboHuangaXiFuaYongliangHuangbXufanZhangcFengmingYoudShijieLia

doi : 10.1016/j.jep.2022.115158

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Seed extract of Thai Mucuna pruriens (L.) DC. var. pruriens enhances sexual performance and improves male reproductive damages in ethanol-induced rats

NareelakTangsrisakdaabTherachonKamollerdaChayakornTaotoaSudtidaBunsuebaChadapornChaimontriaPannawatChoowong-InabeNatthapolLapyuneyongaAlexander TH.WucdfgWipaweeThukhammeebJintanapornWattanathornbSupatchareeArunaTarineeSawatpanichaSitthichaiIamsaardab

doi : 10.1016/j.jep.2022.115219

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Smilax glabra Roxb. flavonoids protect against pathological cardiac hypertrophy by inhibiting the Raf/MEK/ERK pathway: In vivo and in vitro studies

DantingFuab1JiangfengZhoua1ShanchunXue1JueTucYueqinCaicJingyanLiudZhaoweiCaiacDejunWangac

doi : 10.1016/j.jep.2022.115213

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Comprehensive fecal metabolomics and gut microbiota for the evaluation of the mechanism of Panax Ginseng in the treatment of Qi-deficiency liver cancer

ZongHouaFengruiSongbJunpengXingbZhongZhengbShuLiubZhiqiangLiubc

doi : 10.1016/j.jep.2022.115222

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Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease through regulating intestinal flora and inhibiting TAK1/p38MAPK/p65NF-κB pathway

HongZhaoaLingzhouKongaMengtingShaoaJiayueLiuaChanghaiSunaChangxuLiaYanyanWangaXueChaiaYuliangWangaYuZhangaXiaoliangLiab

doi : 10.1016/j.jep.2022.115225

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Prediction of the mechanisms of action of Zhibai Dihaung Granule in cisplatin-induced acute kidney injury: A network pharmacology study and experimental validation

ZhenLiuYeXuXinmingBaiLvqianGuoXinranLiJunlingGaoYuouTengPengYu

doi : 10.1016/j.jep.2022.115241

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Antibiotic pretreatment promotes orally-administered triptolide absorption and aggravates hepatotoxicity and intestinal injury in mice

Yu-TingLiua1Ye-QingHua1Yu-LinWangaKaiHuangbcGao-FengChenbcHuaZhouaCheng-HaiLiubcTaoYangac

doi : 10.1016/j.jep.2022.115224

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Morus mesozygia leaf extract ameliorates behavioral deficits, oxidative stress and inflammation in Complete Freund’s adjuvant-induced arthritis in rats

Oluwakemi O.AriyoaAbayomi M.AjayiaBennethBen-AzuabAdegbuyi O.Aderibigbea

doi : 10.1016/j.jep.2022.115202

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Ethnopharmacological impact of Melaleuca rugulosa (Link) Craven leaves extract on liver inflammation

Heba E.Elsayeda1Hassan Y.Ebrahima1Mohamed S.MadyaMohamed A.KhattabbElsayed K.El-SayedcFatma A.Moharrama

doi : 10.1016/j.jep.2022.115215

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Cucurbitacin E glucoside alleviates concanavalin A-induced hepatitis through enhancing SIRT1/Nrf2/HO-1 and inhibiting NF-ĸB/NLRP3 signaling pathways

Gamal A.MohamedaSabrin R.M.IbrahimbcDina S.El-AgamydeWael M.ElsaedfAlaaSirwiaHani Z.AsfourgAbdulrahman E.KoshakaSameh S.Elhadya

doi : 10.1016/j.jep.2022.115223

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Anti-inflammatory effects of Eclipta prostrata Linné on house dust mite-induced atopic dermatitis in vivo and in vitro

Yun-MiKangaHye-MinKimaHwanLeebDong-SungLeebHyo-JinAna

doi : 10.1016/j.jep.2022.115233

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Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways

M.S.PoornimaabG.SindhuaAbrahamBilluabC.R.SruthiabP.NishaabPinkuGogoicGakulBaishyacK.G Raghuab

doi : 10.1016/j.jep.2022.115237

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Co-treatment with natural HMGB1 inhibitor Glycyrrhizin exerts neuroprotection and reverses Parkinson’s disease like pathology in Zebrafish

QingyuRenabc1XinJiangabd1Yam NathPaudele1XinGaoab1DailiGaoabPengyuZhangabcWenlongShengabXueliangShangcKechunLiuabXiujunZhangcMengJinab

doi : 10.1016/j.jep.2022.115234

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Inhibition of influenza virus replication by Apiaceae plants, with special reference to Peucedanum japonicum (Sacna) constituents

RyokoKanazawaaRyosukeMorimotoa1YukaHorioaHidenobuSumitanibYujiIsegawaa

doi : 10.1016/j.jep.2022.115243

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Acetylcholinesterase inhibition and antioxidant activity properties of Petiveria alliacea L.

Lizeth M.Zavala-OcampoaEvaAguirre-HernándezbPerla Y.López-CamachocRenéCárdenas-VázquezdAlejandroDorazco-GonzálezeGustavoBasurto-Islasf

doi : 10.1016/j.jep.2022.115239

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Chemical characterization and DPP-IV inhibitory activity evaluation of tripeptides from Gynura divaricata (L.) DC.

XinyuanYea1LingXionga1QifengFuaBinyouWangaYiweiWangacKailianZhangaJieYangabFahsaiKantawongbWaruneeKumsaiyaibJieZhouadefCaiLanadefJianmingWuadefJingZenga

doi : 10.1016/j.jep.2022.115203

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History and the immunostimulatory effects of heat-processed licorice root products with or without honey

MisatoOtaToshiakiMakino

doi : 10.1016/j.jep.2022.115108

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Corrigendum to “A traditional Chinese medicine formula inhibits tumor growth in mice and regulates the miR-34b/c-Met/β-catenin pathway� [J. Ethnopharmacol. 260 (2020) 113065]

Ya-PingWangab1Xiu-QiongFuab1Cheng-LeYinabJi-YaoChouabYu-XiLiuabJing-XuanBaiabYing-JieChenabYingWuabJia-YingWuabXiao-QiWangabBinLiuabcZhi-LingYuabde

doi : 10.1016/j.jep.2022.115260

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