International Journal of Radiation Oncology Biology Physics




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Issue Highlights page

doi : 10.1016/S0360-3016(22)00108-0

Volume 112, Issue 5, 1 April 2022, Pages A8-A10

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Fast and Furious: New Data Examining Accelerated Radiation Therapy for Limited-Stage Small Cell Lung Cancer

CliffordRobinsonMD*Timothy J.KruserMD†DawnOwenMD, PhD‡JosephSalamaMD§Megan E.DalyMD||

doi : 10.1016/j.ijrobp.2021.12.151

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Controversy of Adjuvant Locoregional Therapy for Node-Positive Anal Mucosal Melanoma

Stephanie K.SchaubMDEdward Y.KimMD

doi : 10.1016/j.ijrobp.2018.07.004

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The Goldilocks Spot for Radiation Therapy in Anorectal Melanoma: Yes to the Primary Site After Local Excision; No to the Groin

B. AshleighGuadagnoloMD, MPH

doi : 10.1016/j.ijrobp.2018.07.008

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Excise and Ionize

Tobias R.ChapmanMDMatthew J.AbramsMD

doi : 10.1016/j.ijrobp.2018.11.031

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Defer Dissection: Radiation Therapy and Systemic Therapy

MeriemMokhtechMDKimberly L.JohungMD, PhD

doi : 10.1016/j.ijrobp.2021.12.169

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Locoregional-Directed Therapy Is Still a Cornerstone of Anorectal Melanoma Management

DevaratiMitraMD, PhD

doi : 10.1016/j.ijrobp.2021.12.170

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Understanding the Differences Between Bayesian and Frequentist Statistics

IsabellaFornacon-WoodMRes*HiteshMistryPhD*CorinneJohnson-HartPhD†CorinneFaivre-FinnPhD*‡James P.B.O'ConnorPhD*§Gareth J.PricePhD*†

doi : 10.1016/j.ijrobp.2021.12.011

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A Survey to Assess and Delineate Approaches to Medical Student Outreach to Promote Diversity at Academic Radiation Oncology Programs

Malcolm D.MattesMD*CurtilandDeville JrMD†

doi : 10.1016/j.ijrobp.2021.12.165

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Delivery of Adjuvant Radiation in 5 Days or Less After Lumpectomy for Breast Cancer: A Systematic Review

FrankViciniMD*JamesBroughmanMD†AhmedHalimaMD†ZacharyMayoMD†ElizabethObiBS†ZahraaAl-HilliMD‡DouglasArthurMD§DavidWazerMD§|ChiragShahMD†

doi : 10.1016/j.ijrobp.2021.11.026

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Ten-Year Outcomes of Hypofractionated Postmastectomy Radiation Therapy of 26 Gy in 6 Fractions

FabienMignotMD, MSc*LaurentQueroMD, PhD*SophieGuillermMD*BethsabéeBenadonMD*MounaLabidiMD*CarolineCuvierMD†SylvieGiacchettiMD†HenriLorphelinMD‡LaurenceCahen-DoidyMD‡LuisTeixeiraMD, PhD†MarcEspieMD, PhD†ChristopheHennequinMD, PhD*

doi : 10.1016/j.ijrobp.2021.12.154

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Salvage Low-Dose-Rate Prostate Brachytherapy: Clinical Outcomes of a Phase 2 Trial for Local Recurrence after External Beam Radiation Therapy (NRG Oncology/RTOG 0526)

JuanitaCrookMD, FRCPC*Joseph P.RodgersMS†Thomas M.PisanskyMD‡Edouard J.TrabulsiMD§Mahul B.AminMD‖WilliamBicePhD¶GerardMortonMD#Albert D.MurthaMD��EricVigneaultMD, MSc††JoelleHelouMD, MSc‡‡Jeff M.MichalskiMD, MBA, FASTRO§§MackRoachIIIMD, FACR, FASTRO‖‖DavidBeyerMD¶¶Ashesh B.JaniMD, MSEE, FASTRO##Eric M.HorwitzMD, FABS, FASTRO���AdamRabenMD†††StephaniePughPhD†HowardSandlerMD‖‖‖

doi : 10.1016/j.ijrobp.2021.10.138

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Prostate Cancer Patients to Reap the Benefits of “Seeds� Planted by NRG Oncology/RTOG 0526

NilujaThiruthaneeswaranMBBS, PhD*†Sandra L.TurnerMBBS, PhD*†

doi : 10.1016/j.ijrobp.2021.12.149

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Patterns of Prostate Cancer Recurrence After Brachytherapy Determined by Prostate-Specific Membrane Antigen–Positron Emission Tomography and Computed Tomography Imaging

SrinivasRamanMD�MiraKeyesMD, FRCPC�JustinOhMD�EtienneRousseauMD†AndraKrauzeMD�DonWilsonMD†FrançoisBénardMD†

doi : 10.1016/j.ijrobp.2021.12.164

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Impact of Local Recurrence on Cause-Specific Death After Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer: Dynamic Prediction Using Landmark Model

KazuhitoUekiMD�YukinoriMatsuoMD, PhD�AtsuyaTakedaMD, PhD†SatoshiMoritaPhD‡MasatakaTaguriPhD§NorikoKishiMD�HidekiHanazawaMD�YuichiroTsurugaiMD, PhD†TakashiMizowakiMD, PhD�

doi : 10.1016/j.ijrobp.2021.11.025

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Acute and Late Esophageal Toxicity After SABR to Thoracic Tumors Near or Abutting the Esophagus

Quaovi H.SodjiMD, PhD*†RyanKoBS*Rievon EybenMS*Susan G.OwenMS, BSN, RN�Dante P.I.CapaldiPhD*KarlBushPhD*Michael S.BinkleyMD, MS*†FahadAlrowaisMD*BillPickthornMS*Peter G.MaximPhD‡Michael F.GensheimerMD*†MaximilianDiehnMD, PhD�†Billy W.LooJrMD, PhD*†

doi : 10.1016/j.ijrobp.2021.12.008

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Real-World Safety and Efficacy of Consolidation Durvalumab After Chemoradiation Therapy for Stage III Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis

YuWangMD*#TaoZhangMD*#YilinHuangMS†WeiLiMD*JingjingZhaoPhD*YinYangMD*CanjunLiMD*LuhuaWangMD‡NanBiPhD, MD�

doi : 10.1016/j.ijrobp.2021.12.150

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Comprehensive Next-Generation Sequencing Reveals Novel Predictive Biomarkers of Recurrence and Thoracic Toxicity Risks After Chemoradiation Therapy in Limited Stage Small Cell Lung Cancer

LiLiMD�†1ShanshanTangMD�†1Jiani C.YinPhD‡LihuaDongMD, PhD§ZheYangMD║YuepingLiuMD#JieMaMD��PengyuChangMD, PhD§JiaohuiPangMSc‡HuaBaoPhD‡DianbinMuMD††XiaoliZhengMD, PhD‡‡ReyidaAishajiangMD§KewenHeMD�†ShaotongZhangMD§§MengNiMD*XueWuPhD‡XiaonanWangPhD‡…ShuanghuYuanMD, PhD�†‡‡

doi : 10.1016/j.ijrobp.2021.12.009

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Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study

StéphanieSmetMD*†SofiaSpampinatoPhD‡RichardPötterMD§Ina M.Jürgenliemk-SchulzMD, PhD║Remi A.NoutMD, PhD¶#CyrusChargariMD, PhD��UmeshMahantshettyMD††‡‡AlinaSturdzaMD, FRCPC§BarbaraSegedinMD, PhD§§║║KjerstiBruheimMD, PhD¶¶PeterHoskinMD, FRCR##BhavanaRaiMD, DNB���FleurHuangMD†††RachelCooperMD, FRCR‡‡‡ElzbietaVan der Steen-BanasikMD§§§MaritSundsetMD║║║ErikVan LimbergenMD, PhD¶¶¶Li TeeTanMD����…KathrinKirchheinerMSc, PhD§

doi : 10.1016/j.ijrobp.2021.11.022

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Pseudoprogression Is Frequent After Front-Line Radiation Therapy in Pediatric Low-Grade Glioma: Results From the German Low-Grade Glioma Cohort

AnnikaStockMD*†Caroline-ViktoriaHanckenMD*DanielaKandelsMD‡Rolf-DieterKortmannMD§StefanDietzschMD§BeateTimmermannMD||TorstenPietschMD¶BrigitteBisonMD*†ReneSchmidt#MirkoPhamMD*Astrid KatharinaGnekowMD‡MonikaWarmuth-MetzMD*†

doi : 10.1016/j.ijrobp.2021.12.007

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Quality of Life After Stereotactic Body Radiation Therapy Versus Conventional Radiation Therapy in Patients With Bone Metastases

Bart J.PielkenroodMD*RoxanneGalPhD*NicolienKaspertsMD†Joost J.C.VerhoeffMD, PhD†Marcia M.T.J.BartelsMD*EnricaSeravalliPhD†Yvette M.van der LindenMD, PhD‡Evelyn M.MonninkhofPhD§Jorrit-JanVerlaanMD, PhD||Joanne M.van der VeldenMD, PhD†Helena M.VerkooijenMD, PhD*

doi : 10.1016/j.ijrobp.2021.12.163

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Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma

GuodongChenPhD*†PeizhongKongPhD*†MiaomiaoYangMSc*‡§WanglaiHuPhD||Kevin M.PrisePhD¶K.N.YuPhD#��ShujunCuiMSc*‡FengQinMSc*‡GangMengPhD§††Waleed AbdelbagiAlmahiMSc*‡LiliNieMSc*†WeiHanPhD*†‡‡

doi : 10.1016/j.ijrobp.2021.11.023

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Low Expression of ECT2 Confers Radiation Therapy Resistance Through Transcription Coupled Nucleolar DNA Damage Repair

YanfangQiuPhD�†1WenfengHuPhD�†1MingWenPhD�†‡§║WenchaoZhaoPhD�†JinruXieMD�†JiaoZhangMD�†MengWangMD�†HanghangLiMD�†YajieZhaoPhD�ShujunFuPhD�†ZhuoxianRongPhD�†MianfengYaoPhD#YumeiDuanPhD��JunHuangPhD††YiWangPhD‡‡JunQinPhD‡‡HuiWangPhD§§Lun-QuanSunPhD�†‡§║RongTanPhD�†‡§║║║

doi : 10.1016/j.ijrobp.2021.12.010

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Radiation Therapy Promotes Hepatocellular Carcinoma Immune Cloaking via PD-L1 Upregulation Induced by cGAS-STING Activation

Shi-SuoDuMD, PhD�1Gen-WenChenPhD�1PingYangMD�Yi-XingChenMD�YongHuPhD�Qian-QianZhaoPhD�YangZhangPhD�RongLiuMD†Dan-XueZhengMS�JianZhouMD, PhD‡JiaFanMD, PhD‡Zhao-ChongZengMD, PhD�

doi : 10.1016/j.ijrobp.2021.12.162

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miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway

TengLiuMD�†Dong-mingWuMD�†FengZhangMD�†TingZhangMD�†MiaoHeMD�†Yang-yangZhaoMD�JinLiMD�LiLiMD�YingXuPhD�†

doi : 10.1016/j.ijrobp.2021.12.003

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The Impact of Tumor Treating Fields on Glioblastoma Progression Patterns

MartinGlasMD*Matthew T.BalloMD†Ze'evBomzonPhD‡NoaUrmanMSc‡ShayLeviBSc‡GititLavy-ShahafPhD‡SuriyaJeyapalanMD, MPH§Terence T.SioMD, MS||Paul M.DeRoseMD¶MartinMischMD#SophieTaillibertMD��ZviRamMD††Andreas F.HottingerMD, PhD‡‡JacobEasawMD§§Chae-YongKimMD, PhD||||SuyashMohanMD, PDCC¶¶RogerStuppMD##

doi : 10.1016/j.ijrobp.2021.12.152

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The Impact of Tumor Treating Fields on Glioblastoma Progression Patterns

YiLaoPhD*DanRuanPhD*AprilVassantachartMD†ZhaoyangFanPhD‡Jason C.YeMD†Eric L.ChangMD†RobertChinMD, PhD*TaniaKaprealianMD*GabrielZadaMD, MS§Mark S.ShiroishiMD‡KeShengPhD*WenshaYangPhD†

doi : 10.1016/j.ijrobp.2021.12.153

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In Regard to Mutter et al.

HenkStruikmansMD, PhDMirjam E.MastMSc, PhDAnna L.PetoukhovaPhDPhilip M.PoortmansMD, PhD

doi : 10.1016/j.ijrobp.2021.12.156

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In Reply to Struikmans et al.

Robert W.MutterMDJ. IsabelleChoiMDRachel B.JimenezMDYoulia M.KirovaMDMarcioFagundesMDBruce G.HafftyMDRichard A.AmosMSc, FIPEMJulie A.BradleyMDPeter Y.ChenMDXuanfengDingPhDAntoinette M.CarrMDLeslie M.TaylorBSN, RNMarkPankuchPhDRaymond B. MailhotVegaMD, MPHAlice Y.HoMDPetra WittNyströmMD, PhDLisa A.McGeeMDJames J.UrbanicMD…Shannon M.MacDonaldMD

doi : 10.1016/j.ijrobp.2021.12.155

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In Regard to Steenbakkers et al.

SezinYuce SariMDGozdeYaziciMD

doi : 10.1016/j.ijrobp.2021.12.167

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In Reply to Sari and Yazici

Roel J.H.M.SteenbakkersMD, PhDMaria I.van Rijn-DekkerMDMonique A.StokmanPhDRoel G.J.KierkelsPhDArjenvan der SchaafPhDJohanna G.M.van den HoekMDHendrik P.BijlMD, PhDMaria C.A.KramerMD, PhDRob P.CoppesPhDJohannes A.LangendijkMD, PhDPetervan LuijkPhD

doi : 10.1016/j.ijrobp.2021.12.168

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Early Toxicity and Patient Reported Outcomes From a Phase 2 Trial of FDG-PET Response-Based De-Escalated Definitive Radiotherapy for p16+ Oropharynx Cancer

S.G.Allen1B.S.Rosen1M.P.Aryal1Y.Cao1M.Schipper2K.Casper3S.B.Chinn3K.Malloy3M.E.Prince3A.J.Rosko3A.Shuman3M.Spector3C.L.Stucken3P.L.Swiecicki4F.Worden4J.C.Brenner3D.A.Elliott1C.Schonewolf1…M.L.Mierzwa1

doi : 10.1016/j.ijrobp.2021.12.014

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Non-Inferiority Margin and Nodal Analysis of De-Escalated Adjuvant Radiation Therapy (DART) for HPV-Related Oropharyngeal Squamous Cell Carcinoma (OPSCC): A Preplanned Pooled Analysis of MC1273 & MC1675

D.J.Ma1K.Price2E.J.Moore3S.H.Patel4M.L.Hinni5B.Fruth6N.R.Foster6K.Van Abel3L.X.Yin7M.A.Neben-Wittich8Y.Garces9L.A.McGee10J.C.Rwigema11D.M.Routman8S.C.Lester8D.L.Price7J.R.Janus12A.V.Chintakuntlawar2…R.L.Foote9

doi : 10.1016/j.ijrobp.2021.12.015

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Detection of Occult Recurrence Using Circulating HPV Tumor DNA Among Patients Treated for HPV-driven Oropharyngeal Squamous Cell Carcinoma

B.Berger1G.J.Hanna2M.Posner34E.Genden5C.Del Vecchio Fitz1S.P.Naber1C.Kuperwasser1

doi : 10.1016/j.ijrobp.2021.12.016

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Kinetics of Circulating Human Papillomavirus (cHPV) DNA in Plasma and Oral Gargles From Patients with HPV-Positive Oropharyngeal Cancer (OPC) Treated with Definitive Radiation Therapy

M.Echevarria1C.H.Chung2A.Giuliano3R.Slebos2G.Q.Yang4P.J.Stevens5J.J.Caudell6

doi : 10.1016/j.ijrobp.2021.12.017

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A Clinically Translatable, Extensively Validated Immune-based Classification of Human Papillomavirus-Associated Head and Neck Cancer With Implications for Treatment Deintensification and Immunotherapy

P.Zeng12M.Cecchini2J.Barrett1M.Shammas-Toma1L.De Cecco3M.Serafini3S.Cavalieri4L.Licitra4F.Hoebers5R.Brakenhoff6C.Leemans6K.Scheckenbach7T.Poli8X.Wang9X.Liu9F.Laxague1E.Prisman10C.Poh101112…A.Nichols115

doi : 10.1016/j.ijrobp.2021.12.018

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Predicted Th2 Infiltrate is Associated with Outcome in HPV(-) Head and Neck Cancer.

M.K.Abdelhakiem1R.Bao2R.L.Ferris3J.Heymach4C.Pickering5J.J.Luke6H.D.Skinner1

doi : 10.1016/j.ijrobp.2021.12.019

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Loss of HPV 16- E2 Predicts Disease Free Survival and Promotes Platinum Resistance in Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma

M.E.Heft-NealJ.D.SmithS.E.EllspermanA.BhangaleM.LudwigB.JewellJ.MannN.MichmerhuizenM.SpectorJ.C.Brenner

doi : 10.1016/j.ijrobp.2021.12.020

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Neoadjuvant Immunoradiotherapy in a Tobacco-Signature Preclinical Oral Squamous Cell Carcinoma Model

R.Saddawi-Konefka1R.A.Msari1R.N.Jones1S.Sadat1I.Franiak-Pietryga1A.Sharabi2J.S.Gutkind3J.A.Califano4

doi : 10.1016/j.ijrobp.2021.12.021

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HPV E5 Mediates Resistance to PD-1 Checkpoint Blockade Via Inhibition of MHC and IFN Pathway

S.Miyauchi1S.Kim1L.Zhang2K.Guram3R.N.Jones4J.S.Gutkind5L.K.Mell6E.Cohen7J.A.Califano8A.Sharabi1

doi : 10.1016/j.ijrobp.2021.12.022

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An Artificial Intelligence Ultrasound Platform for Screening and Staging of Thyroid Cancer

R.Paul1A.Juliano2W.Faquin3A.W.Chan1

doi : 10.1016/j.ijrobp.2021.12.023

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Development of a Deep Learning-Based Auto-Segmentation of Organs at Risk for Head and Neck Radiotherapy Planning

J.Koo1K.Latifi2J.J.Caudell3P.Jordan4S.Shen4P.M.Adamson4V.Feygelman2

doi : 10.1016/j.ijrobp.2021.12.024

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Safety and Efficacy of RP1 + Nivolumab in Patients with Non-Melanoma Skin Cancer of the Head and Neck: Results From IGNYTE Phase 1/2 Multi-Cohort Clinical Trial

J.Niu1M.Milhem2A.M.Vanderwalde3B.Chmielowski4G.Beasley5A.Samson6J.J.Sacco7T.Bowles8T.Jew9S.He9S.Raza9K.Harrington10M.R.Middleton11

doi : 10.1016/j.ijrobp.2021.12.025

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A Novel Intratumoral Microdosing Approach for Simultaneously Evaluating Multiple Drugs and Combinations in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC)

J.Houlton1H.Cash2H.Xu2P.L.Swiecicki3S.B.Chinn4D.R.Clayburgh5R.J.Li5R.J.Christian6A.Halfpenny6A.vanZante7B.A.Hatton8K.H.W.Sottero8G.Kung8M.O.Grenley8C.Burns8E.Beirne8R.A.Klinghoffer8D.Huszar910…K.Kannan10

doi : 10.1016/j.ijrobp.2021.12.026

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EAT During RT: Towards Data-Driven Goal Setting for Oral Intake Throughout RT as a Function Preservation Strategy

C.E.Barbon1C.B.Peterson2J.Reddy3A.C.Moreno3F.M.Johnson4C.D.Fuller3S.Lai5K.A.Hutcheson5

doi : 10.1016/j.ijrobp.2021.12.027

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Efficacy and Safety of Tisotumab Vedotin in Patients with Head and Neck Squamous Cell Carcinoma: Results From a Phase II Cohort

D.S.Hong1A.Birnbaum2C.Steuer3M.Taylor4T.J.George5J.Lacy6B.Wang7F.Beca7L.Nicacio7I.Soumaoro8M.Cho9

doi : 10.1016/j.ijrobp.2021.12.028

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Stereotactic Ablative Radiotherapy for Early-Stage Glottic Larynx Carcinoma: Results From the Phase II LT-SABR Study

D.J.SherV.AvkshtolD.T.VoD.H.MoonM.H.LinJ.DubasL.ChildsT.MauB.Sumer

doi : 10.1016/j.ijrobp.2021.12.029

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Standard but Not Equal: Disparities in Advanced Radiotherapy Techniques for Head and Neck Cancer in the United States

N.S.McCall1Y.Liu2J.Janopaul-Naylor1J.E.Bates1J.S.Remick1S.Rudra1S.D.Karam3A.Amini4M.W.McDonald1W.A.Stokes1

doi : 10.1016/j.ijrobp.2021.12.030

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Focal Adhesion Kinase Drives Resistance to Therapy in HPV-Negative Head and Neck Squamous Cell Carcinoma in a p53-Dependent Manner

P.Pifer1M.Kumar2L.Yang3T.Xie4M.Frederick5A.Hefner6B.M.Beadle7A.Dhawan6D.Molkentine8J.Molkentine8J.N.Myers9C.Pickering10J.Heymach11H.D.Skinner12

doi : 10.1016/j.ijrobp.2021.12.031

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Institutional Comparison between Radiation with Concurrent Cisplatin Versus Carboplatin/paclitaxel for Squamous Cell Carcinoma of the Head and Neck (SCCHN)

M.Abousaud1M.Shepherd2F.Lozano2B.Fowowe2Y.Cao3S.Rudra4W.A.Stokes4N.C.Schmitt5M.W.El-Deiry6M.R.Patel7C.Steuer8D.M.Shin9Y.Liu10N.F.Saba9

doi : 10.1016/j.ijrobp.2021.12.032

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Analysis of Outcomes by Smoking Status in a Phase III Trial of De-Escalated Adjuvant Chemoradiation Therapy in Human Papillomavirus (HPV(+)) Oropharyngeal Squamous Cell Carcinoma (OPSCC)

P.W.McGarrah1D.M.Routman2D.J.Ma2K.Van Abel3E.J.Moore3S.H.Patel4M.L.Hinni5B.Fruth6N.R.Foster6L.X.Yin3M.A.Neben-Wittich2Y.Garces2L.A.McGee4J.C.Rwigema4D.L.Price3J.R.Janus7A.V.Chintakuntlawar1P.Savvides8…K.Price1

doi : 10.1016/j.ijrobp.2021.12.033

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A Prospective Study of Mucosal Sparing Proton Beam Therapy in Resected Oropharyngeal Cancer Patients

S.H.Patel1D.J.Ma2T.H.Nagel3E.J.Moore4J.C.Rwigema1M.A.Neben-Wittich2L.A.McGee1R.E.Hayden3R.L.Foote5L.R.Crujido3T.A.DeWees6M.A.Golafshar6A.Anand1M.Y.Halyard1M.L.Hinni7

doi : 10.1016/j.ijrobp.2021.12.034

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Omission of the Pathologic Node-Negative Neck From Postoperative Radiation Therapy for Oral Cavity Cancer

J.Hara1N.S.Ecanow2S.Uddin3A.J.Rosenberg4A.Pearson5D.Chan6E.A.Blair6N.Agrawal7N.Cipriani8M.Lingen8E.E.Vokes5Z.Gooi6D.J.Haraf1A.Juloori1

doi : 10.1016/j.ijrobp.2021.12.035

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Management of Positive Main Specimen Margin in Oral Tongue Cancer

R.T.Judd1L.Zhang1S.Zhao1C.Rygalski1M.M.Li2B.Swendseid1D.M.Blakaj3A.Agrawal2E.Ozer2R.Carrau2T.Teknos4K.VanKoevering5J.W.Rocco4M.Old6N.Seim7C.T.Haring1S.Kang6

doi : 10.1016/j.ijrobp.2021.12.036

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Adjuvant Oropharynx Cancer Management in the Era of Tors and HPV: A Recursive Partitioning Analysis

J.Janopaul-Naylor1M.Rupji2J.Lorenz1J.Switchenko2J.E.Bates1M.W.McDonald1D.M.Shin3B.J.Boyce4W.A.Stokes1

doi : 10.1016/j.ijrobp.2021.12.037

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Optimal Threshold of Neutrophil-Lymphocyte Ratio and its Association with Survival Outcome Among Patients with Head and Neck Cancer in the United States

S.J.Ma1M.Khan2J.Gill3S.Santhosh2U.Chatterjee1A.J.Iovoli1M.K.Farrugia1K.E.Wooten1V.Gupta4R.Mcspadden1H.Yu1M.Kuriakose1M.Markiewicz3W.L.Hicks1M.E.Platek5M.Seshadri1A.D.Ray1E.Repasky1A.K.Singh1

doi : 10.1016/j.ijrobp.2021.12.038

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Does Operability Status Influence Outcomes in Patients with T4 Larynx Cancer Undergoing Larynx Preservation?

A.Schlafstein1S.Goyal2A.Amini3S.D.Karam4N.F.Saba5A.S.Kaka6A.H.Aiken7J.J.Beitler8W.A.Stokes8

doi : 10.1016/j.ijrobp.2021.12.039

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Predictors of Occult Nodal Involvement in Clinically Node Negative Primary Parotid Carcinoma: An NCDB Analysis

J.Lorenz1Y.Liu2S.Goyal3J.S.Remick1S.Rudra4S.Hanasoge1D.S.Yu15C.Steuer6W.A.Stokes1

doi : 10.1016/j.ijrobp.2021.12.040

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Elective Neck Treatment for Clinically Node-Negative Salivary Gland Cancer: Observation, Neck Dissection, or Neck Irradiation?

E.Ilori1B.Hair2L.Rybicki3B.B.Burkey4J.L.Geiger5E.Lamarre4B.Prendes4J.Ku4D.Chute6C.Griffith6N.M.Woody1S.Koyfman1S.R.Campbell1

doi : 10.1016/j.ijrobp.2021.12.041

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Have We Made Progress in Early Stage Vocal Cord Cancer with Impaired Cord Mobility?

A.N.De Leo1R.Dagan2C.G.Morris1A.L.Holtzman2K.E.Hitchcock1C.M.Bryant2R.J.Amdur1W.M.Mendenhall1

doi : 10.1016/j.ijrobp.2021.12.042

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The Number of Radiographically Positive Lymph Nodes is Predictive of Survival in HPV-Associated Oropharyngeal Cancer and Further Stratifies Outcomes Beyond Clinical Staging Alone

R.O.Kowalchuk1K.Van Abel2A.Sauer2L.X.Yin3J.J.Garcia4W.S.Harmsen5E.J.Moore2D.L.Price3A.V.Chintakuntlawar6K.A.Price7S.C.Lester1M.A.Neben-Wittich1S.H.Patel8R.L.Foote9D.J.Ma1A.A.Nagelschneider10D.M.Routman1

doi : 10.1016/j.ijrobp.2021.12.043

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Utility of Intermediate Risk Volumes in Human Papilloma Associated Oropharyngeal Cancer: A Pattern of Failure Analysis

G.Q.Yang1M.Echevarria2J.J.Caudell3

doi : 10.1016/j.ijrobp.2021.12.044

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Acute Toxicity Profile and Early Efficacy Results of De-Escalated, Risk-Directed Post-Operative Adjuvant Therapy for Human Papillomavirus-Positive Oropharynx Squamous-Cell Carcinoma: A Phase 2 Trial

Z.Jose1W.L.Thorstad2R.S.Jackson1P.Oppelt3J.Ley4M.D.Daly2R.C.Paniello1P.Pipkorn1J.Rich5S.Puram6J.Liu7H.A.Gay8M.Jacobs9D.Adkins10

doi : 10.1016/j.ijrobp.2021.12.045

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Trilynx: A Phase 3 Trial of Xevinapant and Concurrent Chemoradiotherapy (CRT) for Locally Advanced Head and Neck Cancer

J.D.Schoenfeld1E.Cohen2C.M.Nutting34L.Licitra5B.Burtness67M.Omar8F.Bouisset8H.Nauwelaerts8Y.Urfer8C.Zanna8J. BourhisSr9

doi : 10.1016/j.ijrobp.2021.12.046

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EVOLVE: Evaluating the Safety of De-escalated Head and Neck Irradiation in HPV Positive Oropharynx Cancer in Non/Minimal Smokers.

M.J.Blanchard1A.Terrell2R.Vegunta1S.Powell3R.K.Nowak4D.Almquist1A.Schmidt1B.Bloch1K.Shafique2L.Geeraerts1S.R.W.Nurkic1A.W.Jensen1C.Ellison5W.Spanos3

doi : 10.1016/j.ijrobp.2021.12.047

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Brain Global Structural and Network Topological Alterations in Long-term Nasopharyngeal Cancer Survivors

R.PaulA.W.Chan

doi : 10.1016/j.ijrobp.2021.12.048

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Association of Body Mass Index with Survival Outcome in Patients with Head and Neck Cancer Treated with Combined Modality Therapy

S.J.Ma1M.Khan2A.J.Iovoli1M.K.Farrugia1K.E.Wooten1V.Gupta3R.Mcspadden1M.Kuriakose1W.L.Hicks1M.E.Platek4A.K.Singh1

doi : 10.1016/j.ijrobp.2021.12.049

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Outcomes of Patients With Adenosquamous Carcinoma of the Head and Neck after Definitive Treatment

D.S.Buchberger1S.R.Campbell1S.Wu2E.Lamarre3B.Prendes3J.Ku3J.Scharpf3R.R.Lorenz3N.Silver3C.Griffith4J.L.Geiger5E.Yilmaz5S.Koyfman1N.M.Woody1

doi : 10.1016/j.ijrobp.2021.12.050

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Factors Predictive of Primary Therapeutic Modality in Early-Stage Oropharyngeal Squamous Cell Carcinoma

J.E.Bates1W.A.Stokes1J.S.Remick1S.Rudra1M.W.McDonald1C.Steuer2D.M.Shin3A.S.Kaka4N.F.Saba2M.R.Patel4

doi : 10.1016/j.ijrobp.2021.12.051

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Optimal Threshold of Pre-Treatment Hemoglobin Level as a Prognostic Biomarker for Survival Outcome in Patients with Head and Neck Cancer in the Era of Human Papillomavirus

S.J.Ma1M.Khan2J.Gill3S.Santhosh2U.Chatterjee1A.J.Iovoli1M.K.Farrugia1K.E.Wooten1V.Gupta4R.Mcspadden1H.Yu1M.Kuriakose1M.Markiewicz3W.L.Hicks1M.E.Platek5M.Seshadri1A.D.Ray1E.Repasky1A.K.Singh1

doi : 10.1016/j.ijrobp.2021.12.052

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DEHART: Dose-Escalated Hypofractionated Adaptive Radiation Therapy with Atezolizumab for Head and Neck Cancers

M.J.Awan1S.Tarima2J.Zenga2E.S.Paulson1C.J.Schultz2M.E.Shukla3S.Firat2A.Shreenivas2B.Campbell2B.Massey2M.Stadler2M.Agarwal2S.Wong2

doi : 10.1016/j.ijrobp.2021.12.053

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Locoregional Recurrence Trends in Head and Neck Cutaneous Squamous Cell Carcinoma

A.J.JonesK.N.PowellM.G.MooreA.MantravadiM.SimJ.Yesensky

doi : 10.1016/j.ijrobp.2021.12.054

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Dosimetric Comparison of Intensity Modulated Radiotherapy (IMRT) and Intensity Modulated Proton Therapy (IMPT) for Novel Oral Tongue Avoidance Concept in Low-Risk Squamous Cell Carcinoma of the Oral Tongue

R.H.Press12L.Hu1S.Huang1S.Hasan1I.J.Choi13C.B.SimoneII13A.M.Chhabra12D.Gelblum3R.Kabarriti4S.Sharma2R.L.Bakst2J.Cracchiolo5S.M.McBride3N.Y.Lee3

doi : 10.1016/j.ijrobp.2021.12.055

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Treatment Implications for Complete Pathologic Responders to Neoadjuvant Immunotherapy

M.Fiorella1Z.Elliott1J.Johnson23J.M.Curry34D.Cognetti13R.Axelrod23V. BarAd35A.Luginbuhl16

doi : 10.1016/j.ijrobp.2021.12.056

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Neoadjuvant QUAD Shot as Temporizing Measure Prior to Definitive Surgery for Locally Advanced Oral Cavity Cancer

M.L.Truong1M.L.Hsieh1C.Henson1G.A.Krempl2

doi : 10.1016/j.ijrobp.2021.12.057

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Organ Preservation with Definitive Chemoradiotherapy for T4 Laryngeal Squamous Cell Carcinoma

J.Hara1N.S.Ecanow2A.J.Rosenberg3A.Pearson4S.Kochanny5Z.Gooi6B.J.Baird6E.A.Blair6N.Agrawal7E.E.Vokes4D.J.Haraf1A.Juloori1

doi : 10.1016/j.ijrobp.2021.12.058

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Induction Chemotherapy with Cisplatin, Paclitaxel, and Capecitabine (PTC) in Locally Advanced (LA) Squamous Cell Carcinoma of Head and Neck (SCCHN)

J.F.Alvarado-Muñoz1A.Reyes-Morales1V.Puac-Polanco2G.Bruixola3M.Chivalan1S.Torselli1

doi : 10.1016/j.ijrobp.2021.12.059

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Total Number of Lymph Nodes in Neck Dissection and its Relation to Cancer-Positive Lymph Nodes as a Prognostic Indicator in Aerodigestive Tract Cancers

M.A.Nujoom1H.Z.Marzouki1R.K.Al-Wassia23

doi : 10.1016/j.ijrobp.2021.12.060

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The Impact of Head and Neck Multidisciplinary Clinic on Treatment Package Time During the COVID-19 Pandemic: A Single Institutional Experience

S.Khaja1C.T.Wilke2

doi : 10.1016/j.ijrobp.2021.12.061

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Prognostic Significance of Referral Patterns and Time Trends in Head and Neck Cancer Management

D.Balchander1D.Hoying2C.I.Cabrera1K.Shorbaji1K.Clancy1N.Fowler1J.E.Thuener1P.Lavertu1T.N.Teknos3R.P.Rezaee1S.Li1A.Tamaki1

doi : 10.1016/j.ijrobp.2021.12.062

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Genetic Ancestry and Variants Correlate with the Risk of HPV Oral Infection in Adult Healthy Men

J.Deeken1P.Kothiyal2H.Wang3G.Jo2S.Hazrati2E.McNair2R.Iyer2G.L.Maxwell2

doi : 10.1016/j.ijrobp.2021.12.063

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The Effects of the COVID-19 Pandemic on Cancer Staging in Patients Diagnosed With Head and Neck Cancer at an Academic Health Center

D.Mack1H.Spencer1K.Wang2G.D.Lewis3

doi : 10.1016/j.ijrobp.2021.12.064

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Access to Care for Head and Neck Cancer Patients: The Influence of Expanded Medicaid in Louisiana

M.Noonan1J.Pang1T.Li2M.A.N.Bhuiyan1C.A.O.Nathan1M.T.Yim1

doi : 10.1016/j.ijrobp.2021.12.065

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Head and Neck Cancer Incidence and Trends Differ by Site, Race, and Sex

A.Mazul1S.Chidambaram12S.Massa2

doi : 10.1016/j.ijrobp.2021.12.066

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Temporal Trends in Oropharyngeal Cancer Incidence, Survival, and Cancer-Directed Surgery Among Elderly Americans

S.Chidambaram1S.Hong1M.C.Simpson1N.Osazuwa-Peters2G.M.Ward3S.Massa1

doi : 10.1016/j.ijrobp.2021.12.067

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The Medicare Effect on Head and Neck Cancer Diagnosis and Survival

J.B.Smith1S.Hong1R.Jayanth2M.C.Simpson1S.Massa1

doi : 10.1016/j.ijrobp.2021.12.068

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Association Between Glycosyltransferase Expression and Survival in Head and Neck Cancer

B.Montesino1N.Hu2J.M.Lozano3R.Sackstein1K.B.Chandler1

doi : 10.1016/j.ijrobp.2021.12.069

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Imaging Radiomic Biomarkers of Mandibular Osteoradionecrosis for Head and Neck Cancer

A.S.Mohamed1A.Abusaif2A.Moawad2L.V.van Dijk1D.Fuentes3K.Elsayes2C.D.Fuller1S.Lai4

doi : 10.1016/j.ijrobp.2021.12.071

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Auto-Segmentation of Oropharyngeal Cancer Primary Tumors Using Multiparametric MRI-Based Deep Learning

K.A.Wahid1S.Ahmed1R.He1L.V.van Dijk1J.Teuwen2B.McDonald1V.Salama1A.S.Mohamed1T.Salzillo1C.Dede1N.Taku1S.Lai3C.D.Fuller1M.Naser1

doi : 10.1016/j.ijrobp.2021.12.072

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Diagnostic Accuracy of FNA to Determine HPV Status in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

R.Morse1B.Beaty2L.Scanga3J.Blumberg4S.Patel5C.Shen1B.S.Chera1

doi : 10.1016/j.ijrobp.2021.12.073

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Identification of Extracapsular Extension in Head and Neck Cancer Patients Using Artificial Intelligence.

Y.Wang1T. VengaloorThomas2W.N.Duggar2P.R.Roberts2R.T.Gatewood3L.Bian1H.Wang1

doi : 10.1016/j.ijrobp.2021.12.074

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Changes in Organs at Risk Dose Estimates Due to Anatomic Changes and Registration Method During Head and Neck Radiotherapy and its Relationship to Percent Weight Loss

A.Z.DiazP.D.SoniS.P.Srivastava

doi : 10.1016/j.ijrobp.2021.12.075

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PET/CT Prediction of Head and Neck Melanoma Nodal Metastases

J.L.Farlow1S.Moorman1N.S.Peddireddy1K.K.Wong1C.L.Stucken2

doi : 10.1016/j.ijrobp.2021.12.076

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Novel VMAT Planning Technique Improves Dosimetry for Head and Neck Cancer Patients Undergoing Definitive Chemoradiotherapy

D.DiBartoloT.J.CarpenterJ.P.SantoroD.W.EblingJ.A.HaasJ.W.LischalkM.R.WittenM.RybsteinA.E.VaeziM.C.Repka

doi : 10.1016/j.ijrobp.2021.12.077

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Prospective Study of PET/MRI Tumor Response During Chemoradiotherapy for Patients with Low and Intermediate Risk p16-positive Oropharynx Cancers

M.E.Witek1A.Burr2G.Avey3J.Y.Bruce4T.Chandereng5R.J.Kimple2J.BrowerJr6P.M.HarariJr7

doi : 10.1016/j.ijrobp.2021.12.078

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Pathologic Comparison of Locally Advanced p16-Negative and p16-Positive Larynx Squamous Cell Carcinoma

J.D.Cohen1P.Dontu2K.Hatten3R.Mehra4J.Wolf5R.Taylor6J.Papadimitriou7M.E.Witek8

doi : 10.1016/j.ijrobp.2021.12.079

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Contemporary Radiotherapy for Fisch-Classified Jugulotympanic Paragangliomas - Does Tumor Category Matter? Outcomes From a 13-Year Experience

F.L.Ampil1A.Sin1C.A.O.Nathan2D.Smith1G.Mankekar1

doi : 10.1016/j.ijrobp.2021.12.080

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Impact of Routine Surveillance Imaging on Detecting Recurrence in Sinonasal Malignancies

K.King1S.Roy1R.Rauch2P.Escobedo2M.Bhayani1N.P.Joshi1

doi : 10.1016/j.ijrobp.2021.12.081

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IMRT Head and Neck Cancer Treatment Plans with a Novel Fast Ring-Gantry Radiotherapy System

O.M.OderindeD.SeelyS.M.Shirvani

doi : 10.1016/j.ijrobp.2021.12.082

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Differential Activation of Cancer-Associated Fibroblasts in HPV-Associated Head and Neck Squamous Cell Carcinoma Patients Detected Using Spatial Transcriptomics

S.Sussman1A.Linnenbach2L.Harshyne3A.South4G.Kumar5A.Alnemri6Z.Urdang7L.Anderson-Pullinger8M.Mahoney4A.Argiris8J.Johnson9A.Luginbuhl10U.Martinez-Outschoorn9J.M.Curry11

doi : 10.1016/j.ijrobp.2021.12.083

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Phase 1/2 Study of Pepinemab in Combination with Pembrolizumab as First-Line Treatment of Advanced, Recurrent or Metastatic Head and Neck Cancer (KEYNOTE B84)

T.L.Fisher1E.E.Evans1C.Mallow1A.Foster1M.Boise1E.Smith1J.E.Leonard1M.Chaney2J.T.Beck3S.Hager4N.F.Saba5C.Steuer5D.Adkins6B.Burtness7M.Zauderer1

doi : 10.1016/j.ijrobp.2021.12.084

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A Phase 2/3, Randomized, Open-Label Study of Bempegaldesleukin Plus Pembrolizumab vs. Pembrolizumab Alone in First-Line Treatment of Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma with PD-L1-Expressing Tumors (PROPEL-36)

T.Y.Seiwert1R.I.Haddad2D.Johnson3M.Gillison4U.Keilholz5M.Tahara6J.P.Machiels7J.Deeken8V.Villaflor9Y.Su10T.Guthrie11D.M.Shin12K.De Block13A.Meirovitz14D.Chien15M.Tagliaferri15J.Zalvesky15K.Harrington16

doi : 10.1016/j.ijrobp.2021.12.085

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Lachnoclostridium and Immune Inflamed Gene Expression Signature Association in Head & Neck Cancers

E.Yilmaz1A.Yalamanchali2M.E.Dwidar3J.L.Geiger1S.Koyfman4T.A.Chan4N.Silver5

doi : 10.1016/j.ijrobp.2021.12.086

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Preliminary Safety of PDS0101 (Versamune +HPVmix) and Pembrolizumab Combination Therapy in Subjects with Recurrent/Metastatic Human Papillomavirus-16 Positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)

L.Wood1A.V.Chintakuntlawar2K.Price2J.Kaczmar3G.Conn1F.K.Bedu-Addo1J.Weiss4

doi : 10.1016/j.ijrobp.2021.12.087

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Impact of Tobacco, Marijuana and Alcohol Use on Overall Survival in Recurrent Metastatic Head and Neck Cancer Patients Treated with Immune Checkpoint Inhibitors

M.Issa1M.Husain1B.Klamer2G.Laliotis3N.Mladkova4V.Karivedu1P.Bhateja1K.Dibs4J.Pan2J.C.Grecula4S.R.Jhawar4M.Old1D.L.Mitchell4S.Baliga4R.Carrau5J.W.Rocco6D.M.Blakaj4M.Bonomi1

doi : 10.1016/j.ijrobp.2021.12.088

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Immunotherapy Response in Cutaneous Squamous Cell Carcinoma Patients with Cranial Nerve Involvement

N.Lopetegui1D.Dima1D.S.Buchberger2L.Roof1R.R.Lorenz3B.Prendes3J.Ku3E.Lamarre3J.Scharpf3N.L.Silver3L.Schwartzman4J.L.Geiger1N.M.Woody2S.R.Campbell2S.Koyfman2E.Yilmaz1

doi : 10.1016/j.ijrobp.2021.12.089

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Role of TMB and PD-L1 as Prognostic Factors and Predictors of Response to Immunotherapy in Head and Neck Squamous Cell Cancer

M.Porosnicu1K.Burcher1J.W.Lantz2E.Gavrila1J.T.Burcher3R.T.Hughes4T.Lycan5P.M.Bunch6W.Zhang7R.D'AgostinoJr8

doi : 10.1016/j.ijrobp.2021.12.090

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Immunotherapy Response in Patients with Pre-Existing Autoimmune Disorders and Head and Neck Cancers

C.Y.Han1C.W.R.Fitzgerald2J.Cevallos3M.Lee4C.Valero2L.G.Morris2

doi : 10.1016/j.ijrobp.2021.12.091

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Outcomes Following Immunotherapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Single-Institution Experience

A.Yalamanchali1K.Yang2L.Schwartzman3S.R.Campbell2N.L.Silver4N.M.Woody2C.Griffith5V.Cracolici5D.Chute5S.Koyfman2J.L.Geiger6E.Yilmaz6

doi : 10.1016/j.ijrobp.2021.12.092

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Role of Tertiary Lymphoid Structures and Immunotherapy in Head & Neck Squamous Cell Carcinoma

P.Hannikainen1A.Luginbuhl2

doi : 10.1016/j.ijrobp.2021.12.093

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Patterns of Failure and Cost Analysis for Integrating a Novel Tumor HPV DNA Assay Into HPV-Associated Oropharyngeal Squamous Cell Carcinoma (HPV+OPSCC) Recurrence Surveillance

M.Lin1C.McLaughlin2J.Garneau3P.W.Read4

doi : 10.1016/j.ijrobp.2021.12.094

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Stereotactic Body Radiation Therapy (SBRT) Following Salvage Surgery for Previously Irradiated Head and Neck Cancer

A.Lee1X.A.Wang2H.Wang2A.C.Moreno1J.Reddy1M.T.Spiotto1G.B.Gunn1D.I.Rosenthal1C.D.Fuller1W.H.Morrison1S.J.Frank1R.Ferrarotto3N.D.Gross4R.P.Goepfert4A.M.Gillenwater4A.C.Hessel4S.Y.Su4E.Y.Hanna4…J.Phan1

doi : 10.1016/j.ijrobp.2021.12.096

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Quad-Shot Radiotherapy in Combination with Immune Checkpoint Inhibition for Advanced/Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: A Single-Arm Pilot Study

R.T.Hughes1T.Lycan2P.M.Bunch3K.M.Greven1B.A.Frizzell1C.M.Furdui4R.D'AgostinoJr5P.Triozzi2W.Zhang6M.Porosnicu2

doi : 10.1016/j.ijrobp.2021.12.097

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Real-World Patient Characteristics and Time on Treatment Outcomes Among Patients Receiving First-Line Pembrolizumab in the Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) in the United States

L.WangC.BlackK.RamakrishnanV.Turzhitsky

doi : 10.1016/j.ijrobp.2021.12.098

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A Phase 2 Study of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

A.D.Colevas1J.J.Park2B.Fang3J.Shao4L.U'Ren4J.Odegard4I.Lal4M.Phan5K.Z.Thein6D.Adkins7

doi : 10.1016/j.ijrobp.2021.12.099

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Post-Operative Hypothyroidism Predicts Fistula Development Following Salvage Oropharyngectomy

A.Prince1Z.Huttinger2M.E.Heft-Neal1J.R.Brennan3S.B.Chinn4K.Malloy4C.L.Stucken4K.Casper4M.E.Prince4M.Spector1A.J.Rosko4

doi : 10.1016/j.ijrobp.2021.12.100

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Phase 2 LEAP-009: Lenvatinib (Lenva) With or Without Pembrolizumab (Pembro) vs. Chemotherapy (Chemo) for Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) That has Progressed on Platinum and Immunotherapy

K.Harrington1E.Cohen2L.Siu3D.Rischin4L.Licitra5J.Vermorken6Q.T.Le7M.Tahara8J.P.Machiels9N.Hawk10J.Ge11B.Bidadi11R.Swaby11B.Burtness12

doi : 10.1016/j.ijrobp.2021.12.101

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Clinical Variables Associated with Survival and Treatment Response in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

C.T.Haring1L.Kana2S.Dermody1J.D.Smith1J.C.Brenner1K.Casper1S.B.Chinn1K.Malloy1M.L.Mierzwa3M.E.Prince1A.J.Rosko1C.Schonewolf3J.L.Shah3C.L.Stucken1A.Shuman1M.Spector4F.Worden4P.L.Swiecicki5

doi : 10.1016/j.ijrobp.2021.12.102

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Stereotactic Ablative Radiotherapy for Dural Recurrence of Esthesioneuroblastoma

C.D.Goodman1H.Wang2K.Diao1F.DeMonte3A.S.Garden1E.Y.Hanna4A.Lee1A.C.Moreno1S.M.Raza5J.P.Reddy6D.I.Rosenthal1M.Spiotto1S.Y.Su4J.Phan1

doi : 10.1016/j.ijrobp.2021.12.103

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Immune and Tumor Genome Signatures Associated with Response to Radiotherapy and Chk-1 Inhibition in a Phase 1b Clinical Trial for Patients with Head and Neck Squamous Cell Carcinoma

C.A.Clark1D.della Manna2L.Nabell3C.D.Willey2J.A.Bonner2M.C.Dobelbower2S.A.Spencer2E.S.Yang2

doi : 10.1016/j.ijrobp.2021.12.104

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Evaluating the Therapeutic Potential of a Small Molecule ATR Inhibitor Combined with Radiotherapy for Head and Neck Squamous Cell Carcinoma

D.OdhiamboA.M.BassilR.CastilloD.G.KirschY.M.Mowery

doi : 10.1016/j.ijrobp.2021.12.105

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HPV16-A1 Genotype is Associated with Poor Recurrence-Free Survival in HPV16 Associated Squamous Cell Carcinoma of the Oropharynx

T.P.Schrank1L.Landess2W.H.Stepp3H.Rehmani2W.Weir2N.Lenze4A.Lal2S.Jefferys2J.Blumberg2S.Patel1C.Lumley1T.Hackman1N.Issaeva1W.Yarbrough1

doi : 10.1016/j.ijrobp.2021.12.106

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Decreased Expression of PTENP1 by Smoking Induces Drug Resistance Through c-MYC Activation in HPV+ Oropharyngeal Squamous Cell Carcinoma

Z.Liu1Z.Jose2

doi : 10.1016/j.ijrobp.2021.12.107

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Detection of Locoregional Minimal Residual Disease Immediately After Surgery Through Multi-Omic Analysis of Tumor-Associated Cell-Free DNA in Surgical Drain Fluid

N.Earland1R.J.Ramirez1P.K.Harris2S.Gerndt1Z.Xu3A.Hearn3J.Szymanski2N.Semenkovich4S.Jasim3A.A.Chaudhuri2

doi : 10.1016/j.ijrobp.2021.12.108

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Stable Reconstitution of Gasdermin-E in a Gasdermin-E-Deficient Head and Neck Squamous Cell Carcinoma Mouse Cell Line Enhances Pyroptosis-Mediated Release of Tumor Immunogenic Molecules

A.Alnemri1S.Wang2M.Wang3M.Domingo-Vidal4A.Linnenbach5U.Martinez-Outschoorn4T.F.Alnemri3E.S.Alnemri3J.M.Curry1

doi : 10.1016/j.ijrobp.2021.12.109

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Antitumor Activity of Tipifarnib and PI3K Pathway Inhibitor in HRAS-associated HNSCC

A.Smith1S.Chan1A.McCloskey1H.Vora1F.Burrows2S.Malik1

doi : 10.1016/j.ijrobp.2021.12.110

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A Phase 0 Master Protocol Utilizing a Novel Intratumoral Microdosing Approach for Simultaneously Evaluating Multiple Drugs and Drug Combinations in Patients with Solid Tumors

T.J.Ow12V.Mehta1A.J.Gersten2J.G.Newman3R.G.Maki4K.R.Gundle5D.R.Clayburgh6R.J.Li6M.Porosnicu7C.A.O.Nathan8B.A.Hatton9K.H.W.Sottero9G.Kung9M.O.Grenley9K.Anderson9R.A.Klinghoffer9

doi : 10.1016/j.ijrobp.2021.12.111

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Targeting PI3Kα/δ and the ErbB Family of Protein-Tyrosine Kinases in Cisplatin-Resistant Head and Neck Squamous Cell Carcinomas

X.Geng1Z.Yang1J.Liao1N.Mirkheshti2R.Mehra3K.J.Cullen4H.Dan1

doi : 10.1016/j.ijrobp.2021.12.112

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Nomogram Using Host and Tumor Factors to Predict Survival in Individual Patients with Well Differentiated Thyroid Cancer

C.Valero1A.Yuan2D.Matsuura2D.Adilbay2M.McGill2V.Harries2A.Shaha1J.Shah1R.M.Tuttle2S.Patel1I.Ganly1

doi : 10.1016/j.ijrobp.2021.12.113

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Head and Neck Sweat Gland Carcinomas: Clinical Characteristics and Patterns of Care

A.J.Gordon1A.Patel1F.Zhou2A.Jacobson3M.Tam4B.Givi3

doi : 10.1016/j.ijrobp.2021.12.114

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Tall Cell Histology – Comparison of T1 Tall Cell Variant and Classical Papillary Thyroid Carcinoma

R.S.R.Woods1C.W.R.Fitzgerald1C.Valero1J.Lopez1L.G.Morris1M.Cohen1R.J.Wong1S.Patel1R.A.Ghossein2R.M.Tuttle3A.Shaha1J.Shah1I.Ganly1

doi : 10.1016/j.ijrobp.2021.12.115

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Adoption of Adjuvant Chemotherapy in High-Risk Salivary Gland Malignancies

A.Patel1A.J.Gordon1M.Tam2B.Givi3

doi : 10.1016/j.ijrobp.2021.12.116

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The Value of Online CME in the Multidisciplinary Care of Patients with NTRK Fusion-Positive Thyroid Cancer

M.A.Worst1A.Carothers1M.Surducan1J.Sipos2L.Wirth3

doi : 10.1016/j.ijrobp.2021.12.117

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Outcomes and Prognostic Factors in Acinic Cell Carcinoma of the Parotid Gland: Mature Results From a Single Institution

P.E.Romine1J.Voutsinas2Q.Wu3M.Tratt1J.J.Liao4U.Parvathaneni4B.Barber1J.Dillon1M.A.Timoshchuk5N.Futran6J.Houlton6G.E.Laramore1R.G.Martins1K.D.Eaton1C.P.Rodriguez7

doi : 10.1016/j.ijrobp.2021.12.118

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The Role of Surgery in Small Differentiated Thyroid Cancer

F.Baidoun1Z.Merjaneh1O.Abdel-Rahman2

doi : 10.1016/j.ijrobp.2021.12.119

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Neuroendocrine Neoplasms of the Oropharynx—A Literature Review

L.Maciejko1V.Palacios2K.Van Abel3T.Halfdanarson4A.V.Chintakuntlawar5P.W.McGarrah5K.Tasche3

doi : 10.1016/j.ijrobp.2021.12.121

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Speech and Swallowing Function Following De-Escalation Adjuvant Chemoradiotherapy or Standard of Care Adjuvant Therapy for HPV Associated Oropharyngeal Carcinoma: A Prospective Randomized Trial

K.Van Abel1K.Price2E.J.Moore1S.H.Patel3M.L.Hinni4B.Fruth5N.R.Foster5L.X.Yin6M.A.Neben-Wittich7L.A.McGee3J.C.Rwigema8D.M.Routman7S.C.Lester7D.L.Price6J.R.Janus9T.H.Nagel4A.V.Chintakuntlawar2P.Savvides10…D.J.Ma11

doi : 10.1016/j.ijrobp.2021.12.122

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Randomized Phase III, Double Blind, Placebo-Controlled Study of Prophylactic Gabapentin for the Reduction of Oral Mucositis Pain During the Treatment of Oropharyngeal Squamous Cell Carcinoma

A.E.Cook1A.Modh2H.Ali3J.Sheqwara3S.Chang4T.Ghanem4S.Momin4V.Wu4S.Tam4S.Money5X.Han6L.Fakhoury1B.Movsas1F.Siddiqui1

doi : 10.1016/j.ijrobp.2021.12.123

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Defining the Psychiatric and Financial Landscape of Mental and Substance Use Disorders in Head and Neck Cancer Patients

S.Baliga1B.Klamer2J.D.Palmer3S.Wells4M.E.Gamez3S.R.Jhawar5D.L.Mitchell3J.C.Grecula3S.Kang4N.Seim6E.Ozer7A.Agrawal7K.VanKoevering8V.Karivedu4P.Bhateja4M.Bonomi4M.Old4J.W.Rocco9…D.M.Blakaj10

doi : 10.1016/j.ijrobp.2021.12.125

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Budget Impact of Keytruda for the Treatment of Patients with Recurrent or Metastatic (R/M) and Locally Advanced (LA) Cutaneous Squamous Cell Carcinoma (cSCC) in the United States

X.J.Li1D.Muston1K.Ramakrishnan1C.Black1R.Hughes2G.Weston2S.Lucherini2

doi : 10.1016/j.ijrobp.2021.12.126

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30-Day Morbidity and Bleeding Rates Associated with Transoral Robotic Surgery for HPV Associated Oropharyngeal Squamous Cell Carcinoma: A Retrospective Analysis of Two Prospective Adjuvant Radiotherapy Deescalation Trials (MC1273 & MC1675)

T.J.Haller1T.J.O'Byrne1E.J.Moore2D.J.Ma3K.A.Price4S.H.Patel5M.L.Hinni6M.A.Neben-Wittich7L.A.McGee5D.L.Price8J.R.Janus9J.L.Kasperbauer8T.H.Nagel6A.V.Chintakuntlawar10P.Savvides11J.J.Garcia12R.L.Foote3K.Van Abel2

doi : 10.1016/j.ijrobp.2021.12.127

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Treatment of Radiation-Induced Xerostomia with INF-g Pre-Licensed Mesenchymal Stromal Cells (MSCs)

C.Paz1G.C.Blitzer2A.Glassey3J.Giri1A.Pennati1O.Ganz1S.Schreiber1K.P.Nickel1C.Kelm-Nelson1C.Vanessa1R.Pohlman1T.Glazer1T.Lunga3D.Robbins3R.Mattison1T.Varghese1S.Thibeault3N.Pulia1…R.J.Kimple2

doi : 10.1016/j.ijrobp.2021.12.128

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Effects of Head and Neck Cancer Diagnosis and Treatment on Patient-Partner Intimacy

M.Fiorella1A.Koka2A.Alnemri3S.Sussman1B.Worster4A.Leader56A.Luginbuhl16

doi : 10.1016/j.ijrobp.2021.12.129

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Long Term Results of a Longitudinal Study of Unmet Survivorship Needs in Patients with Head and Neck Cancer

I.Busca1M.E.Giuliani1J.Weiss1J.Jones2N.K.Quartey3S.H.Huang1A.Toulany4J.Papadakos3J.G.Ringash1

doi : 10.1016/j.ijrobp.2021.12.130

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Post-Treatment Evaluation of Swallowing Function Using Quantitative Videofluoroscopy in Head and Neck Patients Undergoing Immunoradiotherapy or Chemoradiotherapy

H.C.Liu1L.Vitzthum2C.W.Williamson1L.M.Hill3J.Zou4T.J.Nelson1B.Faung1K.Linnemeyer5J.R.Todd1A.Sacco6P.Sanghvi1A.Sharabi1J.A.Califano5L.Blumenfeld5L.K.Mell1

doi : 10.1016/j.ijrobp.2021.12.131

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The Affects of Adjuvant Radiotherapy on Survival in Elderly Patients with Advanced Head & Neck Squamous Cell Carcinoma

J.M.Butkus1M.Crippen2A.Luginbuhl3

doi : 10.1016/j.ijrobp.2021.12.132

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Unilateral vs. Bilateral Radiotherapy for Oropharyngeal Carcinoma: Impact on Long Term Symptom Burden

I.Busca1J.de Almeida2S.H.Huang1J.Su3W.Xu3M.Li3S.V.Bratman1J.Cho1M.E.Giuliani1E.Hahn1A.J.Hope1J.Kim1B.O'Sullivan1J.G.Ringash1J.Waldron1A.Hosni1

doi : 10.1016/j.ijrobp.2021.12.134

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Effectiveness of Gabapentin in Reducing Opioid Requirements after Radiation in Head and Neck Cancer in a Single Institution

D.Gilley1A.Clark2M.Wieser3C.Bollig4L.Dooley5G.Biedermann6

doi : 10.1016/j.ijrobp.2021.12.135

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Risk of Osteoradionecrosis in Reconstructed vs.Native Mandibles in Oral Cavity Cancer Following Intensity-Modulated Radiotherapy

S.Wu1E.Lamarre2M.Fritz3J.Ku2C.A.Reddy4P.Brauer5N.M.Woody4S.R.Campbell4S.Koyfman4

doi : 10.1016/j.ijrobp.2021.12.136

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Observations on Carotid Artery Stenosis Following Neck Irradiation

B.A.Harr1R.M.Kahnert2C.A.Reddy1S.Fryberger1M.Fox1J.Ferrini3D.Ives3S.R.Campbell1E.Yilmaz3L.Schwartzman3N.M.Woody1J.L.Geiger3S.Koyfman1J.Bodmann3

doi : 10.1016/j.ijrobp.2021.12.137

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Patient-Reported Outcomes in Head and Neck Cancer: A Systematic Review of Clinical Trials

A.C.Cao1J.S.Lu2S.B.Hobday1E.Cohen3L.Sun4J.N.Lukens5R.Brody3

doi : 10.1016/j.ijrobp.2021.12.138

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Cannabis Use in Patients with Head and Neck Cancer and Radiotherapy Outcomes

A.M.Williams1M.Gilbert2F.Siddiqui2

doi : 10.1016/j.ijrobp.2021.12.139

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Health Insurance Literacy in Head and Neck Cancer Patients

K.Patel1R.McCormick1L.Kim2A.Otto3A. AlishahiTabriz1Y.R.Hong4J.W.Rocco5A.Nichols6X.Wang1H.Jim1M.Reblin7K.Turner1

doi : 10.1016/j.ijrobp.2021.12.140

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Does Cetuximab Reduce the Risk of Anemia in Patients Undergoing Radiation Therapy for Head and Neck Cancers?

A.I.Ghanem12L.Maahs3R.Gutta3A.Tang4M.Gilbert1S.Arya3Z.A.Saheli3S.Tam5J.Sheqwara6F.Siddiqui1

doi : 10.1016/j.ijrobp.2021.12.141

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Predictive Value of Health-Related Quality of Life on Radiotherapy Related Toxicities in Patients with Head and Neck Cancer

O.Billa1F.Bonnetain2J.Chamois3A.Ligey4V.Ganansia5S.Renard6M.Quivrin7P.Truntzer5N.Vulquin7G.Noel5P.Maingon8S.T.Dabakuyo-Yonli1

doi : 10.1016/j.ijrobp.2021.12.142

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Impact of a Head and Neck Cancer Chemoradiation (HNC CRT) Nurse Practitioner (NP) on Patient Outcomes

A.McCready1M.Quinn1P.Francis1R.Stortz1S.Kuruvilla12P.Stewart12D.A.Palma12P.Lang12N.E.Read12J.Sathya12V.M.Venkatesan12A.Nichols13D.MacNeil13K.Fung13A.Mendez13C.Carreau1S.Hawkins1C.Parker1…E.Winquist12

doi : 10.1016/j.ijrobp.2021.12.143

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The Impact of Nasogastric Feeding Tube on Physiologic Swallow in Head and Neck Cancer Patients: A Multidisciplinary Clinical Trial

M.N.Stevens1E.Hosokawa2A.Hereford2M.West2R.Fleming2K.Sharif3R.Sinard2S.L.Rohde2K.Mannion2A.Langerman2J.Netterville2E.L.Rosenthal2M.C.Topf2

doi : 10.1016/j.ijrobp.2021.12.144

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Incidence of Deep Venous Thrombosis (DVT) in Head and Neck Cancer Patients Receiving IV Fluids (IVF) via Peripheral IV (PIV) Compared to Central Venous Catheter

S.Wing1B.Cham2M.Khan3M.Ploch3S.Reyes3S.Jafri4A.Blanco3

doi : 10.1016/j.ijrobp.2021.12.145

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Marrow Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): Study Protocol for a Phase I Dose Escalation Trial of Patients with Xerostomia after Radiation Therapy for Head and Neck Cancer

G.C.Blitzer1N.Pulia2R.Mattison2T.Varghese2O.Ganz2R.J.Chappell2J.Gallipeau2K.McDowell2R.Meyers2T.Glazer2R.J.Kimple1

doi : 10.1016/j.ijrobp.2021.12.146

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Predictive Molecular Biomarkers for HPV-Associated Head and Neck Squamous Cell Carcinoma

W.Yarbrough1T.P.Schrank1J.Blumberg1S.Patel1T.Hackman1C.Lumley1B.Burtness2N.Issaeva1

doi : 10.1016/j.ijrobp.2021.12.178

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Evaluation of Cell-Free HPV DNA in Patients With HPV-Associated Oropharyngeal Cancer Treated With Induction Chemotherapy and Response-Adaptive Therapy

A.J.Rosenberg1H.Sloane2R.Hasina3K.Schmitt2E.Gramiccioni2J.Fredebohm4F.Jones2E.Izumchenko1N.Agrawal3

doi : 10.1016/j.ijrobp.2021.12.179

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Diagnostic Value of Hormonal Receptor Evaluation in Salivary Duct Adenocarcinoma

S.Shikdar1E.Fowle2H.Razaq3W.Razaq4

doi : 10.1016/j.ijrobp.2021.12.180

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