Journal of Ethnopharmacology




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doi : 10.1016/S0378-8741(21)01038-2

Volume 283, 30 January 2022, 114808

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Ethnobotanical, phytochemical, toxicology and anti-diabetic potential of Senna occidentalis (L.) link; A review

AdelineLum NdeaChika I.ChukwumabOchuko L.ErukainureaMaria S.ChukwumacMotlalepula G.Matsabisaa

doi : 10.1016/j.jep.2021.114663

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Updated evidence of Dengzhan Shengmai capsule against ischemic stroke: A systematic review and meta-analysis

XueyanLiua1YiqiLib1NingningBaic1ChuanyuYuaYunXiaoaChiLidZhiqiangLiua

doi : 10.1016/j.jep.2021.114675

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Tinospora cordifolia (Willd.) Miers: Protection mechanisms and strategies against oxidative stress-related diseases

KaruppusamyArunachalamabXuefeiYangabThae ThaeSanab

doi : 10.1016/j.jep.2021.114540

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Health benefits and biological activities of spiny monkey orange (Strychnos spinosa Lam.): An African indigenous fruit tree

Adeyemi OladapoAremuabMackMoyoc

doi : 10.1016/j.jep.2021.114704

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Isatidis Radix and Isatidis Folium: A systematic review on ethnopharmacology, phytochemistry and pharmacology

JiaoChena1ZongpingZhua1TianhuiGaoaYiChenaQingsongYangaChaomeiFuaYaningZhuaFangWangbWanLiaoa

doi : 10.1016/j.jep.2021.114648

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Invasive alien plants and weeds in South Africa: A review of their applications in traditional medicine and potential pharmaceutical properties

L.J.McGawabA.G.Omokhua-UyiabJ.F.FinnieaJ.Van Stadena

doi : 10.1016/j.jep.2021.114564

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Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. – A critically endangered medicinal plant of the western Himalaya

ShalikaRathoreab1YogRajab1PritamDebnathaManishKumaraRakeshKumarab

doi : 10.1016/j.jep.2021.114613

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Tongqiao Huoxue Decoction for the treatment of acute ischemic stroke: A Systematic Review and meta-analysis

XiuZhouaTianyuShaoaXiuzhenXiebMinruiDingaXuminJiangbPingpingSubZhuqingJinc

doi : 10.1016/j.jep.2021.114693

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Medicinal plants used in traditional Mayan medicine for the treatment of central nervous system disorders: An overview

RodrigoCastañedaaArmandoCáceresbDianaVelásquezcCesarRodríguezaDavidMoralesaAndreaCastilloa

doi : 10.1016/j.jep.2021.114746

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Traditional uses, phytochemistry, pharmacology and current uses of underutilized Xanthoceras sorbifolium bunge: A review

XianqiangChenaZilunLeibJunCaobWenZhangbRongWubFuliangCaobQirongGuobJiahongWangab

doi : 10.1016/j.jep.2021.114747

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Potential nephroprotective phytochemicals: Mechanism and future prospects

ParakhBasistabBushraParveenabSultanZahiruddinaGauravGautamaRabeaParveenaeMohammad AhmedKhanbAnujaKrishnancMohdShahiddSayeedAhmada

doi : 10.1016/j.jep.2021.114743

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Therapeutic effect of baicalin on inflammatory bowel disease: A review

XianWangLongXieJiayingLongKaiLiuJingLuYoudanLiangYiCaoXiaolinDaiXiaofangLi

doi : 10.1016/j.jep.2021.114749

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A review of the traditional use of southern African medicinal plants for the treatment of inflammation and inflammatory pain

Gugulethu P.KhumaloabcBen ErikVan WykdYunjiangFengbcIan E.Cockab

doi : 10.1016/j.jep.2021.114436

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Component-target network and mechanism of Qufeng Zhitong capsule in the treatment of neuropathic pain

Yu-chengLiaoab1Jing-wenWanga1Juan-liZhanga1ChaoGuoa1Xin-liangXucKaiWangaChaoZhaoaAi-dongWenaRui-liLiaYiDinga

doi : 10.1016/j.jep.2021.114532

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Homalium zeylanicum attenuates streptozotocin-induced hyperglycemia and cellular stress in experimental rats via attenuation of oxidative stress imparts inflammation

DeeptimayeeRoutUmesh ChandraDashSatishKanharSandeep KumarSwainAtish KumarSahoo

doi : 10.1016/j.jep.2021.114649

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Randomized double-blind trial comparing low dose and conventional dose of a modified traditional herbal formula Guizhi Fuling Wan in women with symptomatic uterine fibroids

WeiMengabcWai LingLindWing FaiYeungeYangboZhangaErnest Hung YuNggYuen Phin ElaineLeehZhang-JinZhangafiJianhuiRongaLixingLaoafj

doi : 10.1016/j.jep.2021.114676

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Ethnopharmacological evaluation of antioxidant, anti-angiogenic, and anti-inflammatory activity of some traditional medicinal plants used for treatment of cancer in Togo/Africa

P.KolaabeK.MetowogoaS.N.ManjulabG.KatawacH.ElkhenanydK.M.MruthunjayaeK.Eklu-GadegbekuaK.A.Aklikokoua

doi : 10.1016/j.jep.2021.114673

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Protective effect of oligosaccharides isolated from Panax ginseng C. A. Meyer against UVB-induced skin barrier damage in BALB/c hairless mice and human keratinocytes

ZhenzhuoLiab1RuiJiangb1ChenxuJingabJianzengLiuaXiaohaoXuabLiweiSunbcdDaqingZhaoac

doi : 10.1016/j.jep.2021.114677

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Combination of Compound Kushen Injection and cisplatin shows synergistic antitumor activity in p53-R273H/P309S mutant colorectal cancer cells through inducing apoptosis

XingkangWuabYufangLuabXuemeiQinab

doi : 10.1016/j.jep.2021.114690

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Suhuang antitussive capsule ameliorates post-infectious cough in mice through AhR-Nrf2 pathway

RongyaoLianga1XiyangTonga1ZhikuiDongbc1WeiweiQinaLinglingFanaZiyuBaiaZhihaoZhangaTingXiangbZhenWangaNinghuaTana

doi : 10.1016/j.jep.2021.114664

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Herbal medicine for functional dyspepsia: Network meta-analysis of placebo-controlled randomised trials

LeonardHoaClaire CWZhongbCharlene HLWongbJustin CYWucKarina KHChandIrene XYWueTing HungLeungaVincent CHChungab

doi : 10.1016/j.jep.2021.114665

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Mechanism by which Huoxue Tongluo Qiwei Decoction improves the erectile function of rats with diabetic erectile dysfunction

XiaoLia1Jun-LongFengb1Zi-LongChenbe1Bing-HaoBaocHeng-HengDaibFan-ChaoMengbShengDengbBinWangbdHai-SongLibdJi-ShengWangbd

doi : 10.1016/j.jep.2021.114674

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Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic Hedgehog pathway in cerebral infarction

ZhenHuiSuleiWangJianxiangLiJingqingWangZhennianZhang

doi : 10.1016/j.jep.2021.114634

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Comparative in vivo antimalarial activities of aqueous and methanol extracts of MAMA powder - A herbal antimalarial preparation

Emmanuel O.AdeyojuClement O.Ajayi1Awodayo O.AdepitiAnthony A.Elujoba

doi : 10.1016/j.jep.2021.114686

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Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling

JingChenaYingchaoWangaShufangWangaXiaopingZhaobLuZhaoaYiWangac

doi : 10.1016/j.jep.2021.114667

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Thymus persicus (Ronniger ex Rech. f.) Jalas alleviates nociceptive and neuropathic pain behavior in mice: Multiple mechanisms of action

Donya ZiafatdoostAbedaReihanehSadeghianbcSaeedMohammadidMuhammadAkrame

doi : 10.1016/j.jep.2021.114695

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Effect of a combination of Korean red ginseng extract and probiotics on the prevention of atopic dermatitis in a murine model

Se HoonLeeaJeesukYubSang HyunChoa

doi : 10.1016/j.jep.2021.114687

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Protective effect of methanol extract of latex of Calotropis procera in an experimental model of colorectal cancer

Vijay L.KumaraSnehVermaaPrasenjitDasb

doi : 10.1016/j.jep.2021.114668

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Curcumin inhibits the invasion and metastasis of triple negative breast cancer via Hedgehog/Gli1 signaling pathway

MengjieLi1TingtingGuo1JiayiLinXiaHuangQiaodanKeYujianWuChunpingFangChenxiaHu

doi : 10.1016/j.jep.2021.114689

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Alkaloid-rich fraction of Ervatamia coronaria sensitizes colorectal cancer through modulating AMPK and mTOR signalling pathways

NaibedyaDuttaa1Deepak BharadwajPemmarajuab12SuvranilGhoshaAsifAliaAyanMondalaChirantanMajumderaVinod K.NelsoncSubhash C.MandalcAnup K.MisraaAravind K.RenganbVelyuthamRavichandirandChun-TaoCheeKaterina V.GurovafAndrei V.GudkovfMahadebPala

doi : 10.1016/j.jep.2021.114666

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Genotoxicity, nitric oxide level modulation and cardio-protective potential of Kalanchoe Integra Var. Crenata (Andr.) Cuf Leaves in murine models

Isaac JuliusAsiedu-GyekyeaEmmanuelArhinaStella AmaabaArthuraBenoit BangaN'guessanaSeth KwabenaAmponsahb

doi : 10.1016/j.jep.2021.114640

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The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB

Lin-TaoXuTianWangKai-LiFangYuZhaoXiao-NingWangDong-MeiRenTaoShen

doi : 10.1016/j.jep.2021.114694

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Integrated lipidomics, transcriptomics and network pharmacology analysis to reveal the mechanisms of Danggui Buxue Decoction in the treatment of diabetic nephropathy in type 2 diabetes mellitus

LiliSunZhigangYangWeiZhaoQinChenHaiyingBaiShanshanWangLiYangChunmeiBiYanbinShiYingqianLiu

doi : 10.1016/j.jep.2021.114699

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Daphnes Cortex and its licorice-processed products suppress inflammation via the TLR4/NF-κB/NLRP3 signaling pathway and regulation of the metabolic profile in the treatment of rheumatoid arthritis

XianglongMenga1XiaoyanZhanga1XiaojuanSuaXiaoqinLiuaKeleRenaChenxuNingaQiZhangabShuoShengZhanga

doi : 10.1016/j.jep.2021.114657

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Xuanfei Baidu Decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6/STAT3 signaling pathway

YuyingWangab1XiaoqingSangab1RuiShaoab1HonglinQinabXuanhaoChenabcZhifengXueabLinLiabdYuWangeYanZhuabYanxuChangabcXiumeiGaoabdBoliZhangabdHanZhangabdJianYangab

doi : 10.1016/j.jep.2021.114701

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Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome

Guo-QingZhouaGangChenbJuanYangaWen-yiQinaJiaPinga

doi : 10.1016/j.jep.2021.114707

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Sphagneticola trilobata (L.) Pruski-derived kaurenoic acid prevents ovalbumin-induced asthma in mice: Effect on Th2 cytokines, STAT6/GATA-3 signaling, NFκB/Nrf2 redox sensitive pathways, and regulatory T cell phenotype markers

Sergio M.Borghiaf1Talita P.Domicianoa1Fernanda S.Rasquel-OliveiraaCamila R.FerrazaAllan J.C.BussmannaJosiane A.VignolibDoumitCamilios-NetobSergio R.AmbrósiocNilton S.ArakawadeRubiaCasagrandedWaldiceu A.VerriJr.a

doi : 10.1016/j.jep.2021.114708

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In-vitro anti-Helicobacter pylori activity and preliminary mechanism of action of Canarium album Raeusch. fruit extracts

JiahuiYanaChangPengbPengtingChenaWeijiaZhangaChengJiangbShuyiSangbWeixingZhucYuemeiYuandYanjunHongbMeicunYaob

doi : 10.1016/j.jep.2021.114578

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Differences in the chemical composition of Panax ginseng roots infected with red rust

YongxiaGuanaJianweiFanaChenghongSunaYiqingYangdJianyeQuanbGuiminZhangaNaGuoabc

doi : 10.1016/j.jep.2021.114610

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Effects of Jowiseungki-tang on high fat diet-induced obesity in mice and functional analysis on network pharmacology and metabolomics analysis

XianglongMenga1JingningYana1JunnanMabAn NaKangcSeok YongKangcdQiZhangeChenziLyuaYong-KiParkcdHyo WonJungcd2ShuoshengZhanga2

doi : 10.1016/j.jep.2021.114700

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miRNA and miRNA target genes in intervention effect of Zhuyu pill on cholestatic rat model

HanYua1ChaoLiua1JianfeiWangb1JunHancFenghuaZhangaXinZhouaYueqiangWenaTaoShena

doi : 10.1016/j.jep.2021.114709

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Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells

YafeiZhuacQipengZhaobYidengJiangac

doi : 10.1016/j.jep.2021.114652

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The anti-tumor effect of OP-B on ovarian cancer in vitro and in vivo, and its mechanism: An investigation using network pharmacology-based analysis

ShuangYuanabYuanyuanXuabTaoYibHongjingWangab

doi : 10.1016/j.jep.2021.114706

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Inhibition of enzymatic activities of Bothrops asper snake venom and docking analysis of compounds from plants used in Central America to treat snakebite envenoming

PatriciaSaravia-OttenaRosarioHernándezaNereidaMarroquínbJaime A.PereañezcLina M.PreciadocAllanVásquezdGabrielaGarcíaaFedericoNaveeLorenaRochacbVicenteGenovezaMaxMéridabSully M.CruzbNohemíOrozcofArmandoCáceresbgJosé M.Gutiérrezh

doi : 10.1016/j.jep.2021.114710

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Comparative evaluation of anti-inflammatory activity between n-butanol fraction, leaf and stem methanolic extract obtained from Olax psittacorum

RajaMajumderaMoonmunDharabLopamudraAdhikaribAmitavPanigrahic

doi : 10.1016/j.jep.2021.114697

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Crosstalk of LncRNA HOTAIR and SP1-mediated repression of PDK1 contributes to β-Elemene-inhibited proliferation of hepatocellular carcinoma cells

JingJingWua1XiaoJuanTanga1YaoShibChangJuMaaHongyuZhangaJunhongZhangaYueLuaJiananWeiaLiLiaLingHanacd

doi : 10.1016/j.jep.2021.114456

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Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells

YanliangWuaLeiZhaoaLifeiGuaAkhtolkhynTilyekacBoyangYuabChengzhiChaia

doi : 10.1016/j.jep.2021.114696

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Terrestrosin D, a spirostanol saponin from Tribulus terrestris L. with potential hepatorenal toxicity

Xiao-ChenSuna1XiaoSongab1FeiGuoc1Yao-HuiYuanaShu-YueWangaShuaiWangaKun-LinLiuaXi-YuLvaBingHanaChaoZhangaJiang-TingLiud

doi : 10.1016/j.jep.2021.114716

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Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways

HailunJianga1FangXub1LiZengaChenyangLibYanChenbLinlinWangaZhuorongLiaRuiLiua

doi : 10.1016/j.jep.2021.114714

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Investigation of the effective components inhibited macrophage foam cell formation in Ophiopogonis Radix

YuShanTianabShanquanChangabJuntaoXuabPuyangGongabBoYangYuabcJinQiabc

doi : 10.1016/j.jep.2021.114678

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Effects of the Tibetan medicine Byur dMar Nyer lNga Ril Bu on Alzheimer's disease in mice models

JokyabTseringa1QianqianChenb1HonghongLiaYananHanaJinpengWubHuijuanYinbJiashenHubSiyingSubXiafeiShibXiandaHuaBochenCheb

doi : 10.1016/j.jep.2021.114724

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Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway

Jia-shangLi1TaoJi1Shu-lanSuYueZhuXing-lingChenEr-xinShangShengGuoDa-weiQianJin-aoDuan

doi : 10.1016/j.jep.2021.114713

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Yanning Syrup ameliorates the lipopolysaccharide-induced inflammation: Adjusting the gut microbiota, short-chain fatty acids, and the CD4+ T cell balance

DanniWeiPingMaQiqiFanHanchuanYuYingPengXiaoboLi

doi : 10.1016/j.jep.2021.114729

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Anti-nociceptive effects of ECa 233 a standardized extract of Centella asiatica (L.) Urban on chronic neuropathic orofacial pain in mice

AnanyaBuapratoomaAreeWanasuntronwongbOnraweeKhongsombatacMayuree H.Tantisirad

doi : 10.1016/j.jep.2021.114737

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Sambucus nigra: A traditional medicine effective in reducing inflammation in mice

José RobertoSantinaLarissaBenvenuttiaMilena FronzaBroeringaRobertaNunesaFernanda CapitanioGoldonibYasmin Beatrisse KleinPatelbJade Andréde SouzabMainara Adriane TesserKoppbPriscilade SouzaaRita de Cássia Vilhenada SilvaaMaria Verônica DávilaPastorbAngelita Boldieride SouzaaLetícia DebatinTestonicAngélica GarciaCoutoaTania Mari BelleBresolinaNara Lins MeiraQuintãoa

doi : 10.1016/j.jep.2021.114736

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Diaphragma juglandis extracts modifies the gut microbiota during prevention of type 2 diabetes in rats

FengZhanga1DanChenb1LimingZhangaQingyujingZhaocYageMaaXiZhangaShenglanZhaoaChaoyinChend

doi : 10.1016/j.jep.2021.114484

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Panaxadiol inhibits IL-1β secretion by suppressing zinc finger protein 91-regulated activation of non-canonical caspase-8 inflammasome and MAPKs in macrophages

Jing YingWang1YueXing1Ming YueLiZhi HongZhangHong LanJinJuanMaJung JoonLeeYiZhongHong XiangZuoXuejunJin

doi : 10.1016/j.jep.2021.114715

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Pretreatment with the active fraction of Rhodiola tangutica (Maxim.) S.H. Fu rescues hypoxia-induced potassium channel inhibition in rat pulmonary artery smooth muscle cells

RuixiaZhangabcZhanqiangLiabChuanchuanLiuabcQuanyuYangabDianxiangLuabRi-liGeabShuangMaabZhanquanLic

doi : 10.1016/j.jep.2021.114734

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Efficacy and safety of Duhuo Jisheng Decoction add-on bisphosphonate medications in patients with osteoporosis: A meta-analysis of randomized controlled trials

Chung-YuHuangabCiao-JhihChengbcWen-FeiChiouadWei-ChiaoChangaefYi-NoKangghijMei-HsienLeeakl

doi : 10.1016/j.jep.2021.114732

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Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo

SongYangFangyuLiShuyanLuLimeiRenShuaiBianMeichenLiuDaqingZhaoSimingWangJiawenWang

doi : 10.1016/j.jep.2021.114739

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Anti-inflammatory effect of Kaba Sura Kudineer (AYUSH approved COVID-19 drug)-A Siddha poly-herbal formulation against lipopolysaccharide induced inflammatory response in RAW-264.7 macrophages cells

Svenia P.JoseaRatheeshMaSheethalSaSonyRajanaSangeethSajiaVimalNarayananbSandyaSc

doi : 10.1016/j.jep.2021.114738

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Chemical profiling of Fritillariae thunbergii Miq prepared by different processing methods reveals two new quality markers: Zhebeininoside and imperialine-3-β-D-glucoside

Yu-HuaShia1Qin-WeiHuangb1She-MinZhubYue-MeiZhoucLi-JiangZhangaWen-KangHuangeJin-JinShaoaJian-LiangZhoudWen-TingZhangf

doi : 10.1016/j.jep.2021.114670

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Chemical composition and protective effect of cerebrospinal fluid of Dan-Deng-Tong-Nao capsules on brain microvascular endothelial cells injured by OGD/R

QiHuanga1JiajiaQia1ZiruGaoa1LiliLiabcNingWangabdSaiwangSetoeMinYaoaQianqianZhangaLeiWangaRuonanTongaYuyangChenaXiaoyaChenaJincaiHouf

doi : 10.1016/j.jep.2021.114705

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The therapeutic effect of Huazhuojiedu decoction on precancerous lesions in a gastric cancer model via the regulation of lnc 517368

XinyuHaoaPingpingZhouaZeqiYangaTianxiaoYangaYangangWangb

doi : 10.1016/j.jep.2021.114635

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Elucidating the estrogen-like effects and biocompatibility of the herbal components in the Qing' E formula

Jing-linXiongXin-yinCaiZi-jiaZhangQiLiQiangZhouZheng-taoWang

doi : 10.1016/j.jep.2021.114735

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A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway

XiaojingZhangabZhenzhenLiuaShuaipengChenaHangLiaLinDongaXueyanFua

doi : 10.1016/j.jep.2021.114742

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The use of medicinal plants by Paraguayan migrants in the Atlantic Forest of Misiones, Argentina, is based on Guaraní tradition, colonial and current plant knowledge

MonikaKujawskaaGuillermoSchmeda-Hirschmannb

doi : 10.1016/j.jep.2021.114702

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Marantodes pumilum: Systematic computational approach to identify their therapeutic potential and effectiveness

AhmadAzfaralariffaFazialFarahfaiqahcMuhamadShahidaSiti AisyahSanusiaDouglasLawadAbdul RazakMohd IsaeMustadzaMuhamadeTee ThiamTsuifShazrulFazryab

doi : 10.1016/j.jep.2021.114751

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Anti-depressive effects of Jiao-Tai-Wan on CORT-induced depression in mice by inhibiting inflammation and microglia activation

GuiqinBaia1YiqiQiaoa1Po-ChiehLoaLeiSongaYunaYangabLiningDuanacSufenWeiaMinLicShuiqingHuangaBeipingZhangdQiWangaCongYanga

doi : 10.1016/j.jep.2021.114717

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Signature network-based survey of the effects of a traditional Chinese medicine on heart failure

YueWuaMenglanWangaJingXuaJunyingWeiaHongjunYangb

doi : 10.1016/j.jep.2021.114750

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