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“A singular property in my hands”
Phillipa Hay Jose Carlos Appolinario
doi : 10.1111/1756-185X.14032
Volume 24, Issue 1 p. 5-6
COVID?19 and rheumatology: Reflecting on the first wave and preparing for the second wave
Armin Fardanesh Swetha Byravan Arumugam Moorthy Hasan Tahir
doi : 10.1111/1756-185X.14062
Volume 24, Issue 1 p. 7-9
Clinical implications of synovial fluid specimen handling for crystal associated arthritides: A systematic review
Megan M. Meyer Lisa A. Marks Fawad Aslam
doi : 10.1111/1756-185X.14019
Volume 24, Issue 1 p. 10-20
To identify the appropriate methods of synovial fluid (SF) specimen storage, manipulation and handling for crystal associated arthritides (CAA) diagnosis.
Interleukin?35 regulates the balance of Th17 and Treg responses during the pathogenesis of connective tissue diseases
Di Wang Ling Lei
doi : 10.1111/1756-185X.13962
Volume 24, Issue 1 p. 21-27
Interleukin (IL)?35 belongs to the IL?12 cytokine family and is a heterodimer of the p35 and Epstein?Barr virus?induced gene 3 (EBI3) subunits. Functionally, IL?35 can promote the proliferation and activation of regulatory T cells (Tregs) and suppress the function of T helper 17 (Th17) cells and other inflammatory cells to inhibit immune responses. In recent years, an abnormal IL?35 expression causing a Th17/Treg imbalance has been associated with the development and progression of several connective tissue diseases (CTDs), such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), dermatomyositis (DM)/polymyositis (PM), and primary Sj?gren’s syndrome (pSS). Here, we review the role of IL?35 in regulating the balance of Th17/Treg responses in different types of CTDs and provide new insights into the role of IL?35 in these diseases.
A practical guide to interpreting and applying systematic reviews of qualitative studies in rheumatology
Daniel Sumpton Ayano Kelly David Tunnicliffe Jonathan C. Craig Chandana Guha Geraldine Hassett Allison Tong
doi : 10.1111/1756-185X.14014
Volume 24, Issue 1 p. 28-35
While patient?centered care is widely advocated in the management of rheumatic diseases, it can be challenging to implement, particularly for patients with complex systemic conditions. Patient?centered care involves identifying and integrating the patient's experiences, attitudes, and preferences in decision?making. Qualitative research is used to describe patient perspectives and priorities that may not always be expressed in clinical settings. Systematic reviews of qualitative studies can provide new and more comprehensive evidence of patients' beliefs and priorities across different populations and healthcare settings and are increasingly being reported across medical specialties, including rheumatology. In rheumatology, they have been used to examine topics including medication?taking and adherence, coping with systemic sclerosis and conservative management and exercise in osteoarthritis. By referencing recent examples of systematic qualitative reviews in the rheumatology literature, this article will outline the methodology and methods used, and provide an approach to guide the appraisal of reviews. We aim to give the reader a practical understanding of systematic reviews of qualitative literature and elucidate how knowledge gained from such reviews can be applied to improve the care of patients with rheumatic conditions.
Effect of laying on of hands as a complementary therapy for pain and functioning in older women with knee osteoarthritis: A randomized controlled clinical trial
Katy Andrade Monteiro Zacaron Cl?udia Soares dos Santos Cyntia Pace Schmitz Corrêa Yuri Cotta e Silva Isabel Cristina Fonseca Reis Maryana Sant'Ana Sim?es Giancarlo Lucchetti
doi : 10.1111/1756-185X.13952
Volume 24, Issue 1 p. 36-48
To assess the effects of laying on of hands (LooH) as a complementary therapy to kinesiotherapy, on pain, joint stiffness, and functional capacity of older women with knee osteoarthritis (KOA) compared to a control group.
Interferon III?related IL28RA variant is associated with rheumatoid arthritis and systemic lupus erythematosus and specific disease sub?phenotypes
Manuela Nunes Drehmer Gabriel Vaisam Castro Ivanio Alves Pereira Il?ada Rainha de Souza Sara Emelie L?fgren
doi : 10.1111/1756-185X.14015
Volume 24, Issue 1 p. 49-55
The interferon pathways have been commonly implicated in autoimmune disease development but the identity of the genes involved has not yet been fully clarified. Variation in genes involved in interferon pathways is expected to have a role in the etiology of these diseases.
Neutrophil to lymphocyte ratio predicts glucocorticoid resistance in polymyalgia rheumatica
Claire E. Owen Christopher McMaster David F. L. Liew Jessica L. Leung Andrew M. Scott Russell R. C. Buchanan
doi : 10.1111/1756-185X.14000
Volume 24, Issue 1 p. 56-62
Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) correlate with disease activity in several rheumatic diseases; however, their utility in polymyalgia rheumatica (PMR) remains unclear. This study evaluated their relationship with disease activity and glucocorticoid resistance in PMR.
Incidence of giant cell arteritis after bisphosphonate exposure: A retrospective cohort study
Salman Bin Mahmood Yuanyuan Ji Yi Peng Zaki Abou Zahr
doi : 10.1111/1756-185X.14018
Volume 24, Issue 1 p. 63-68
Bisphosphonates may cause autoimmune reactions via a cytokine?mediated acute phase response. A case of giant cell arteritis (GCA) after zoledronate injection was recently reported. We aimed to evaluate this association by reviewing the incidence of GCA after bisphosphonate administration.
Survival and causes of death for Takayasu’s arteritis in Korea: A retrospective population?based study
Shin Yi Jang Taek Kyu Park Duk?Kyung Kim
doi : 10.1111/1756-185X.14005
Volume 24, Issue 1 p. 69-73
Few studies have evaluated survival of Takayasu's arteritis (TAK; M31.4) in Korea. The purpose of this study was to assess the survival rate (SR) and causes of death for TAK.
Development of a Bangla version of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI)
Syed Jamil Abdal Sabrina Yesmin Md. Nahiduzzamane Shazzad Mohammad Abul Kalam Azad Md. Abu Shahin Minhaj Rahim Choudhury Md. Nazrul Islam Syed Atiqul Haq
doi : 10.1111/1756-185X.14008
Volume 24, Issue 1 p. 74-80
Development of a Bangla version of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI).
Evaluation of cognitive function in adult patients with juvenile idiopathic arthritis
Natalia Mena?V?zquez Pablo Cabezudo?Garc?a Fernando Ortiz?M?rquez Gisela D?az?Cordovés Rego Luis Mu?oz?Becerra Sara Manrique?Arija Antonio Fern?ndez?Nebro
doi : 10.1111/1756-185X.14009
Volume 24, Issue 1 p. 81-89
To evaluate cognitive function in adult patients with juvenile idiopathic arthritis (JIA) and associated factors.
Vaspin deficiency failed to promote the proliferation of BMSCs in osteoarthritis
Junfeng Wang Zhongqiang Chen Zhenpeng Guan
doi : 10.1111/1756-185X.14010
Volume 24, Issue 1 p. 90-95
The aim of this study was to estimate the possible role of vaspin in the proliferation of bone mesenchymal stem cells (BMSCs) and its molecular mechanisms in the bone marrow microenvironment of osteoarthritis (OA).
Is being barefoot, wearing shoes and physical activity associated with knee osteoarthritis pain flares? Data from a usually barefoot Sri Lankan cohort
Inoshi Atukorala Arunasalam Pathmeswaran Nishamani Batuwita Nimesha Rajapaksha Vishmi Ratnasiri Lalith Wijayaratne Monika De Silva Thashi Chang Yuqing Zhang David John Hunter
doi : 10.1111/1756-185X.14024
Volume 24, Issue 1 p. 96-105
To identify the association between hours of being barefoot/wearing footwear, physical activity (PA) and knee osteoarthritis pain flares (KOAF).
Joint damage in rheumatoid arthritis: Lessons learned from an extended 36?joint ultrasonography and 28?joint Disease Activity Score assessments
York Kiat Tan HuiHua Li John Carson Allen Jr Julian Thumboo
doi : 10.1111/1756-185X.14013
Volume 24, Issue 1 p. 106-111
To study joint damage severity in rheumatoid arthritis (RA) patients classified using ultrasound power Doppler (PD) and gray?scale (GS) joint inflammation outcomes and the 28?joint Disease Activity Score (DAS28).
Effect of radiographic disease severity in high?resolution quantitative computed tomography assessment of metacarpophalangeal joint erosion and cysts
Anne?Birgitte Garm Blavnsfeldt Rasmus Klose?Jensen Jesper Thygesen Philip Therkildsen Bente Lomholdt Langdahl Kresten Krarup Keller Ellen?Margrethe Hauge
doi : 10.1111/1756-185X.14020
Volume 24, Issue 1 p. 112-119
Bone erosions are the hallmark of rheumatoid arthritis (RA). High?resolution peripheral quantitative computed tomography (HR?pQCT) enables 3?dimensional visualization of arthritic bone erosions at a high resolution. However, the degree of erosive disease could influence the reliability of HR?pQCT evaluation. We aim to assess the intra? and inter?reader variability of identification of erosions in the metacarpophalangeal (MCP) joints using HR?pQCT in healthy controls and patients with RA, stratified according to van der Heijde?modified Sharp Score (HSS) of radiographic erosions.
Ovarian antibodies among SLE women with premature menopause after cyclophosphamide
Martha Tsaliki Kristi A. Koelsch Ambre Chambers Mitali Talsania R. Hal Scofield Eliza F. Chakravarty
doi : 10.1111/1756-185X.14022
Volume 24, Issue 1 p. 120-124
Women with systemic lupus erythematosus (SLE) are at risk of premature ovarian failure when treated with cyclophosphamide. This risk is increased when autoimmune thyroid disease is present. We undertook this study to determine whether the presence of ovarian autoimmunity also increased the risk of early ovarian failure among women receiving cyclophosphamide.
Cricopharyngeal bar and dermatomyositis: A cause of rapidly progressive dysphagia
Cameron Louis Adams Siobhan Lohan Alana Bruce Narainraj Kamalaraj Shyamini Gunaratne Ray White
doi : 10.1111/1756-185X.14006
Volume 24, Issue 1 p. 125-131
Idiopathic inflammatory myopathies (IIM) are immune?mediated conditions that affect striated muscle, and are frequently associated with dysphagia. Dysphagia in these cases can be due to weakness of the muscles involved in swallowing or the presence of restrictive pharyngeal defects, such as cricopharyngeal bars. Treatment of dysphagia in IIM revolves around immunosuppressive therapies, and procedures to disrupt cricopharyngeus muscle when immunosuppressive therapies are unsuccessful.
Is methotrexate effective and safe in patients with psoriatic arthritis? A Cochrane Review summary with commentary
Frane Grubi?i?
doi : 10.1111/1756-185X.13988
Volume 24, Issue 1 p. 132-134
Your help is needed in the fight against COVID?19: Please contribute to the COVID?19 Global rheumatology alliance registry
doi : 10.1111/1756-185X.14052
Volume 24, Issue 1 p. 135
