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How good is “Dr Google”?
Peter K. K. Wong
doi : 10.1111/1756-185X.13945
Volume 23, Issue 12 p. 1611-1612
A systematic review of internet?based information on dermatomyositis and polymyositis
Ashraful Haque Miriam Cox Robert D. Sandler Michael Hughes
doi : 10.1111/1756-185X.13929
Volume 23, Issue 12 p. 1613-1618
Patients with rheumatic diseases are increasingly using internet?based information to inform healthcare utilization and make treatment decisions. Our aim was to assess the readability and quality of internet?based information on dermatomyositis (DM) and polymyositis (PM).
Interleukin?1 receptor?associated kinase gene polymorphisms contribute to rheumatoid arthritis risk: A meta?analysis
Pingli Zhao Qihui Li Renxian Liang Xiong He
doi : 10.1111/1756-185X.13946
Volume 23, Issue 12 p. 1619-1626
Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting about 1% of world population. Three polymorphisms of Interleukin?1 receptor?associated kinase (IRAK1) gene, rs3027898, rs1059702 and rs1059703, are studied to associate with RA risk. However, the findings are inconclusive. Therefore, we performed a meta?analysis to derive a more precise estimation of the impact of the 3 polymorphisms on RA risk.
Nuclear factor??B in rheumatoid arthritis
Jie Li Rong?Shuang Tang Zhou Shi Jin?Qi Li
doi : 10.1111/1756-185X.13958
Volume 23, Issue 12 p. 1627-1635
NF??B (nuclear factor kappa light chain enhancer of activated B cells) signaling pathway is involved in the occurrence and development of various kinds of inflammation, including rheumatoid arthritis (RA). In this paper, the relationship between the activation or inhibition of NF??B and the pathogenesis of RA is discussed. It is found that activated NF??B operates a dual?aspect effect which can either promote or suppress inflammation. When NF??B is inhibited, the symptoms of RA are significantly improved. The specific role of NF??B is closely related to its upstream stimulator and downstream activator. Therefore, we review the research on NF??B in RA over the past 20 years in order to have a clearer understanding of its mechanism.
Quality of English?language videos on YouTube as a source of information on systemic lupus erythematosus
Caitlin Hsuen Ng Grace Rui Si Lim Warren Fong
doi : 10.1111/1756-185X.13852
Volume 23, Issue 12 p. 1636-1644
Many patients turn to online platforms to obtain healthcare information, but the quality and accuracy of the information is largely unknown. The objective of this study was to evaluate the reliability and quality of the most viewed English?language YouTube videos on systemic lupus erythematosus (SLE).
YouTube for information about side effects of biologic therapy: A social media analysis
Orhan Zengin Mustafa Erkut Onder
doi : 10.1111/1756-185X.14003
Volume 23, Issue 12 p. 1645-1650
Biologic therapies are one of the most significant breakthroughs in the treatment of rheumatic diseases, although there is still some uncertainty surrounding long?term patient safety. Recently, a growing number of patients browse the Internet as a source of health?related information. We aimed to assess the quality of information available on YouTube videos regarding the side effects of biologic therapy.
Recognition of spondyloarthritis lesions on magnetic resonance imaging: Results of an educational intervention
Rodrigo Garcia Salinas Josefina Marin Gabriel Aguilar Santiago Ruta Dario Aguerre Xenofon Baraliakos
doi : 10.1111/1756-185X.13991
Volume 23, Issue 12 p. 1651-1655
Magnetic resonance imaging (MRI) is a fundamental diagnostic tool in axial spondyloarthritis (SpA), allowing us an earlier diagnosis of the disease compared to radiography.
Somatosensory dysfunction related neuropathic pain component affects disease activity, functional status and quality of life in ankylosing spondylitis
Emel Atar Ayhan Askin
doi : 10.1111/1756-185X.13993
Volume 23, Issue 12 p. 1656-1663
To investigate the neuropathic pain (NP) component in ankylosing spondylitis (AS) and to assess the relations between NP and disease characteristics.
Interleukin?17A biomarker as a predictor for detection of early axial spondyloarthritis changes in patients with psoriasis
Dalia S. Saif Mohamed A. El Tabl Naglaa Afifi Mahmoud S. Abdallah Sally M. El Hefnawy Shimaa A. Hassanein
doi : 10.1111/1756-185X.13997
Volume 23, Issue 12 p. 1664-1669
Although the pathogenic mechanisms of psoriatic arthritis (PsA) are not completely clarified, evidence suggests that interleukin 17A (IL?17A)?mediated immune responses play a pivotal role in the disease. This is best underscored by the important clinical effectiveness of IL?17A inhibitors in psoriasis treatment. We aim to investigate the predictive value of IL?17A in detecting the early axial spondyloarthropic (SpA) changes in psoriatic patients.
Evaluation of inflammatory rheumatic diseases from an emergency medicine perspective
Ishak San Abdulsamet Erden Emin Gemcioglu Orhan Kücüksahin
doi : 10.1111/1756-185X.13982
Volume 23, Issue 12 p. 1670-1675
Patients with rheumatological complaints may visit an emergency department (ED) because of an acute attack or complication. Because of the recent increased use of immunosuppressant drugs to treat rheumatic diseases, more patients with these conditions visit the ED with a complaint about an infection. However, there are little data on the ED visits of patients with rheumatological complaints. This study evaluated the ED visits of patients with inflammatory rheumatic diseases.
Prevalence of patients with rheumatoid arthritis and age?stratified trends in clinical characteristics and treatment, based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan
Ayako Nakajima Ryoko Sakai Eisuke Inoue Masayoshi Harigai
doi : 10.1111/1756-185X.13974
Volume 23, Issue 12 p. 1676-1684
To estimate the prevalence and age?stratified treatment trends and clinical characteristics of rheumatoid arthritis (RA) in Japan.
Sarcopenia in rheumatoid arthritis: Is it a common manifestation?
Emre Tekgoz Seda Colak Funda Seher Ozalp Ates Ilknur Sonaeren Sedat Yilmaz Muhammet Cinar
doi : 10.1111/1756-185X.13976
Volume 23, Issue 12 p. 1685-1691
To evaluate the presence of sarcopenia in patients with rheumatoid arthritis (RA).
Effects of dehydroepiandrosterone on quality of life in premenopausal women with rheumatoid arthritis: A preliminary randomized clinical trial
Mahnaz Sandoughi Mahmoud Ali Kaykhaei Elnaz Langarizadeh Alireza Dashipour
doi : 10.1111/1756-185X.13975
Volume 23, Issue 12 p. 1692-1697
Chronic inflammation and subsequent use of glucocorticoids can lead to relative adrenocortical insufficiency in patients with rheumatoid arthritis (RA). Previously, adrenocortical hormone, dehydroepiandrosterone (DHEA) was shown as a potential therapy for autoimmune disorders. However, data regarding effects of DHEA in RA are limited. The aim of this study was to investigate the effects of DHEA on quality of life (QOL) in premenopausal rheumatoid arthritis patients.
Anti?carbamylated protein and peptide antibodies as potential inflammatory joint biomarkers in the relatives of rheumatoid arthritis patients
Lorena Chila?Moreno Luz?Stella Rodr?guez Wilson Bautista?Molano Juan?Manuel Bello?Gualtero Alejandro Ramos?Casallas Consuelo Romero?S?nchez
doi : 10.1111/1756-185X.13977
Volume 23, Issue 12 p. 1698-1706
Antibodies against carbamylated proteins/peptide (CarP) have been associated with severity in rheumatoid arthritis (RA) patients. However, their role in risk groups, specific targets and relation with periodontal disease (PD) is uncertain yet. The aim of this study was evaluated the association between the levels of anti?CarP with clinical manifestation, human leukocyte antigen (HLA) alleles, periodontal activity markers, PD diagnosis, PD severity, and presence of Porphyromonas gingivalis (P gingivalis) in relatives of patients with RA.
Delay in seeking medical help in patients with rheumatoid arthritis in India: A qualitative study
Avinash Jain Amita Aggarwal Jo Adams Rachel E. Jordan Steven Sadhra Shirish Dubey Kerry Allen Kanta Kumar
doi : 10.1111/1756-185X.14001
Volume 23, Issue 12 p. 1707-1718
Rheumatoid arthritis (RA) is an autoimmune disease with varied articular and extra?articular manifestations. In developing countries such as India patients with RA often delay seeking medical advice which may impact prognosis and disease burden.
Chinese registry of rheumatoid arthritis (CREDIT): III. The transition of disease activity during follow?ups and predictors of achieving treatment target
Yirong Xiang Qian Wang Hongbin Li Xinwang Duan Yongfei Fang Pingting Yang Qin Li Rui Wu Yuehong Huo Xiaofei Shi Zhenbiao Wu Yanhong Wang Nan Jiang Evelyn Hsieh Mengtao Li Xinping Tian Xiaofeng Zeng Chinese Registry of Rheumatoid Arthritis co?authors
doi : 10.1111/1756-185X.13996
Volume 23, Issue 12 p. 1719-1727
The Chinese Registry of Rheumatoid Arthritis (CREDIT) is the first nationwide multi?center prospective rheumatoid arthritis (RA) registration cohort in China. This study aimed at presenting disease activities transition during follow?ups and identifying predictors to treatment response.
Investigation of the relationship between the pelvic floor and sexual dysfunction in women with Sj?gren’s syndrome
Sebahat Yaprak Cetin Alime Buyuk Ayse Ayan
doi : 10.1111/1756-185X.13998
Volume 23, Issue 12 p. 1728-1733
Women with Sj?gren's syndrome (SS) may have sexual dysfunctions due to vaginal dryness and may also have pelvic floor problems. The aim of this study was to examine the pelvic floor distress of women with SS with a self?reported questionnaire, to compare this group with healthy individuals, and to examine the relationship between pelvic floor problems and sexual dysfunction.
Risk factors for progression and prognosis of primary Sj?gren’s syndrome?associated interstitial lung disease in a Chinese population
Yuetong Xu Junfei Zhou Xin Dong Xiaojuan Guo Yuewu Lu Yi Zheng
doi : 10.1111/1756-185X.14023
Volume 23, Issue 12 p. 1734-1740
This study explored differences between primary Sj?gren's syndrome?associated interstitial lung disease (pSS?ILD) patients with and without ILD progression, and analyzed the factors affecting the progression and prognosis of pSS?ILD.
Does acupuncture improve pain and function in people with hip osteoarthritis? A Cochrane Review summary with commentary
Soo Chin Chan Julia Patrick Engkasan
doi : 10.1111/1756-185X.13948
Volume 23, Issue 12 p. 1741-1743
Your help is needed in the fight against COVID?19: Please contribute to the COVID?19 Global Rheumatology Alliance Registry
doi : 10.1111/1756-185X.14038
Volume 23, Issue 12 p. 1744-1744
