Annals of Internal Medicine




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Mortality Among Persons Entering HIV Care Compared With the General U.S. Population

Jessie K. Edwards, PhD , Stephen R. Cole, PhD , Tiffany L. Breger, PhD , Jacqueline E. Rudolph, PhD , Lindsey M. Filiatreau, PhD , Kate Buchacz, PhD ,

doi : 10.7326/M21-0065

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Treatment of Acute Pain in Adults With Sickle Cell Disease in an Infusion Center Versus the Emergency Department

Sophie Lanzkron, MD, MHS , Jane Little, MD , Hang Wang, PhD , Joshua J. Field, MD , J. Ryan Shows, MD , Carlton Haywood Jr., PhD, MA , Mustapha Saheed

doi : 10.7326/M20-7171

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Frailty and Clinical Outcomes of Direct Oral Anticoagulants Versus Warfarin in Older Adults With Atrial Fibrillation

Dae Hyun Kim, MD, MPH, ScD , Ajinkya Pawar, PhD , Joshua J. Gagne, PharmD, ScD , Lily G. Bessette, BS , Hemin Lee, MD, MPH , Robert J. Glynn, ScD, PhD

doi : 10.7326/M20-7141

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Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening

Willemijn de Klaver, MD, MSc* , Pieter H.A. Wisse, MD, MSc* , Francine van Wifferen, MSc , Linda .W. Bosch, PhD , Connie R. Jimenez, PhD , Ren?© W.M.

doi : 10.7326/M20-8270

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Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality

Mahdi Sheikh, MD, PhD , Anush Mukeriya, MD, DSc , Oxana Shangina, PhD , Paul Brennan, PhD , David Zaridze, MD, DSc

doi : 10.7326/M21-0252

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Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020

Sameer S. Kadri, MD, MS , Junfeng Sun, PhD , Alexander Lawandi, MDCM, MSc , Jeffrey R. Strich, MD, MHS , Lindsay M. Busch, MD , Michael Keller, MD , A

doi : 10.7326/M21-1213

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Prevalence of Symptoms More Than Seven Months After Diagnosis of Symptomatic COVID-19 in an Outpatient Setting

Mayssam Nehme, MD , Olivia Braillard, MD , Fran?§ois Chappuis, MD, PhD , Delphine S. Courvoisier, PhD , Idris Guessous, MD, PhD , on behalf of the Cov

doi : 10.7326/M21-0878

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Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19

Andreas Barratt-Due, PhD , Inge Christoffer Olsen, PhD , Katerina Nezvalova-Henriksen, PhD , Trine K?Â¥sine, MD , Fridtjof Lund-Johansen, PhD , Hedda H

doi : 10.7326/M21-0653

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Management of Blood Pressure in Patients With Chronic Kidney Disease Not Receiving Dialysis: Synopsis of the 2021 KDIGO Clinical Practice Guideline

Charles R.V. Tomson, MA, BM, BCh, DM , Alfred K. Cheung, MD , Johannes F.E. Mann, MD , Tara I. Chang, MD, MS , William C. Cushman, MD , Susan L. Furth

doi : 10.7326/M21-0834

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Effect of Bedside Compared With Outside the Room Patient Case Presentation on Patients' Knowledge About Their Medical Care

Christoph Becker, MD , Martina Gamp, PhD , Philipp Schuetz, MD , Katharina Beck, PhD , Alessia Vincent, PsyM , Seraina Hochstrasser, MD , Kerstin Metz

doi : 10.7326/M21-0909

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Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): Designing Master Protocols for Evaluation of Candidate COVID-19 Therapeutics

Lisa LaVange, PhD , Stacey J. Adam, PhD , Judith S. Currier, MD, MSc , Elizabeth S. Higgs, MD, MIA, DTMH , Lora A. Reineck, MD, MS , Eric A. Hughes, M

doi : 10.7326/M21-1269

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The “Black Fungus� in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis

Sumanth Gandra, MD, MPH , Sanjay Ram, MBBS , Stuart M. Levitz, MD

doi : 10.7326/M21-2354

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The Problem of Aducanumab for the Treatment of Alzheimer Disease

G. Caleb Alexander, MD, MS , Jason Karlawish, MD

doi : 10.7326/M21-2603

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The Case for Mandating COVID-19 Vaccines for Health Care Workers

Michael Klompas, MD, MPH , Madelyn Pearson, DNP, RN , Charles Morris, MD, MPH

doi : 10.7326/M21-2366

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Mandating COVID-19 Vaccination for Health Care Workers

Ezekiel J. Emanuel, MD, PhD , David J. Skorton, MD

doi : 10.7326/M21-3150

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HIV: Closing the Mortality Gap

Marshall J. Glesby, MD, PhD , Roy M. Gulick, MD, MPH

doi : 10.7326/M21-2586

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One Small Step for Sickle Cell Disease: Many More to Go

Julie Kanter, MD

doi : 10.7326/M21-2650

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A Tailored FIT for Improved Colorectal Cancer Screening

Jason A. Dominitz, MD, MHS

doi : 10.7326/M21-2748

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Treating Tobacco Smoking After the Diagnosis of Lung Cancer: It's Not Too Late and a Call to Action

Nancy A. Rigotti, MD

doi : 10.7326/M21-2997

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When COVID-19 Strikes Your Hospital

Vineet Chopra, MD, MSc

doi : 10.7326/M21-2681

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Targeting the Standardized Blood Pressure: New Guidelines for Blood Pressure Management in Chronic Kidney Disease

George Thomas, MD , Crystal A. Gadegbeku, MD

doi : 10.7326/M21-2571

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Bringing Teaching Back to the Bedside

Michael A. LaCombe, MD

doi : 10.7326/M21-2447

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Moral Injury

Venktesh R. Ramnath, MD

doi : 10.7326/M21-0997

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Finding My Voice

Joy Y. Wu, MD, PhD

doi : 10.7326/M21-1587

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Detection of Tropheryma whipplei Genome From the Aqueous Humor by Metagenomic Sequencing

John A. Gonzales, MD , Thuy Doan, MD, PhD , Annemieke VanZante, MD, PhD , Jay M. Stewart, MD , Amol Sura, MD , Amit Reddy, MD , Nailyn Rasool, MD

doi : 10.7326/L20-1470

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Safety and Immunogenicity of a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series

William A. Werbel, MD , Brian J. Boyarsky, MD, PhD , Michael T. Ou, BS , Allan B. Massie, PhD , Aaron A.R. Tobian, MD, PhD , Jacqueline M. Garonzik-Wa

doi : 10.7326/L21-0282

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Absence of Humoral Response After Two-Dose SARS-CoV-2 Messenger RNA Vaccination in Patients With Rheumatic and Musculoskeletal Diseases: A Case Series

Caoilfhionn M. Connolly, MD, MSc , Brian J. Boyarsky, MD, PhD , Jake A. Ruddy, BS , William A. Werbel, MD , Lisa Christopher-Stine, MD, MPH , Jacqueli

doi : 10.7326/M21-1451

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Symptoms After COVID-19 Vaccination in Patients With Persistent Symptoms After Acute Infection: A Case Series

David T. Arnold, MBChB, BSc , Alice Milne, MSc , Emma Samms , Louise Stadon, BSc , Nick A. Maskell, DM , Fergus W. Hamilton, BA, MBChB

doi : 10.7326/M21-1976

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Safety and Immunogenicity of Anti–SARS-CoV-2 Messenger RNA Vaccines in Recipients of Solid Organ Transplants

Olivier Marion, MD , Arnaud Del Bello, MD , Florence Abravanel, PharmD, PhD , Chlo?© Couat, MSc , Stanislas Faguer, MD, PhD , Laure Esposito, MD , Ann

doi : 10.7326/M21-1341

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Medicalized Hotel as an Alternative to Hospital Care for Management of Noncritical COVID-19

Orla Torrallardona-Murphy, MD , Juan M. Peric? s, MD, PhD, MPH , Neus Rabaneda-Lombarte, MD, PhD , Marta Cubedo, DMath, PhD , David Cucchiari, MD, PhD

doi : 10.7326/M21-1873

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A Cross-Sectional Study of SARS-CoV-2 Vaccination Among Employees of an Urban Safety-Net Health Care System

J. Daryl Thornton, MD, MPH , Sherrie Dixon-Williams, MD, MHS , Anne Huml, MD, MS , Adam Perzynski, PhD , Doug Gunzler, PhD , Doug Einstadter, MD, MPH

doi : 10.7326/M21-1513

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The Proportion of SARS-CoV-2 Infections That Are Asymptomatic

Fan Yang, MD , Dan Ma, MD

doi : 10.7326/L21-0490

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The Proportion of SARS-CoV-2 Infections That Are Asymptomatic

Ali Haider Bangash

doi : 10.7326/L21-0489

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The Proportion of SARS-CoV-2 Infections That Are Asymptomatic

Daniel P. Oran, AM , Eric J. Topol, MD

doi : 10.7326/L21-0491

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Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease

Xi Yang, MD , Lilit Karapetyan, MD , John M. Kirkwood, MD

doi : 10.7326/L21-0441

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Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease

Monique K. van der Kooij, MD , Karijn P.M. Suijkerbuijk, MD, PhD , Olaf M. Dekkers, MD, PhD , Ellen Kapiteijn, MD, PhD

doi : 10.7326/L21-0442

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Clinical Practice Guidelines Registry

Elaine Harrow, MA, PgDip , Sara Twaddle, PhD, MSc , Duncan Service, MA(Hons), Dip LIS , Ina B. Kopp, MD , Pablo Alonso-Coello, MD, PhD , Gillian Leng,

doi : 10.7326/L21-0492

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Update Alert: Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 2)

Amir Qaseem, MD, PhD, MHA , Jennifer Yost, PhD, RN , Itziar Etxeandia-Ikobaltzeta, PharmD, PhD , George M. Abraham, MD, MPH , Janet A. Jokela, MD, MPH

doi : 10.7326/L21-0389

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Update Alert 6: Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings

Roger Chou, MD , Tracy Dana, MLS , Rebecca Jungbauer, DrPH

doi : 10.7326/L21-0393

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Correction: Treatment of Acute Pain in Adults With Sickle Cell Disease in an Infusion Center Versus the Emergency Department

doi : 10.7326/L21-0522

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we are forgetting

D.A. Frater, MD

doi : 10.7326/M21-0742

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Care of the Patient With Abnormal Liver Test Results

Ashley N. Tran, MD , Joseph K. Lim, MD

doi : 10.7326/AITC202109210

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ACP provided 2 conditional recommendations on use of high-flow nasal oxygen in acute respiratory failure

Maitri Munsif, MBBS, MPH , Christine F. McDonald, AM, MBBS, PhD

doi : 10.7326/ACPJ202109210-098

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In acute dyspnea with diagnostic uncertainty, ACP suggests POCUS may be added to the standard diagnostic pathway

Jonathan M. Kirschner, MD , Benton R. Hunter, MD

doi : 10.7326/ACPJ202109210-099

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USPSTF found insufficient evidence on benefits and harms of screening for vitamin D deficiency in asymptomatic adults

KoKo Aung, MD, MPH , Thwe Htay, MD

doi : 10.7326/ACPJ202109210-100

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In adults with obesity, metabolic–bariatric surgery vs. usual care is associated with lower all-cause mortality

Scott Kahan, MD, MPH , Adriana Williams, MD

doi : 10.7326/ACPJ202109210-101

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In persons with obesity, exercise plus liraglutide improved weight-loss maintenance vs. exercise or placebo

Shohinee Sarma, MD, MPH , Lorraine L. Lipscombe, MD, MSc

doi : 10.7326/ACPJ202109210-102

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In older adults, cannabinoid-based medicines increase adverse events compared with placebo

Jennifer Watt, MD, PhD

doi : 10.7326/ACPJ202109210-103

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Some disease-modifying osteoarthritis drugs make small improvements in knee and hip osteoarthritis

David S. Pisetsky, MD, PhD

doi : 10.7326/ACPJ202109210-104

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In acute atrial flutter, adding pharmacologic before electrical cardioversion did not increase conversion to normal sinus rhythm

Christopher Sampson, MD

doi : 10.7326/ACPJ202109210-105

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Basal insulin plus GLP-1 RA or SGLT2 inhibitor was noninferior to basal-bolus insulin intensification for HbA1c in T2DM

Miranda K. Boggild, MD, MScCH , Angela M. Cheung, MD, PhD

doi : 10.7326/ACPJ202109210-106

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In suspected COVID-19, RT-PCR with nasal plus throat swabs has 97% sensitivity vs. nasopharyngeal swabs

Dennis G. Maki, MD

doi : 10.7326/ACPJ202109210-107

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Annals Graphic Medicine - Dr. Mom: My Favorite Thing to Say on Rounds

Grace E. Farris, MD

doi : 10.7326/G21-0053

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Annals Graphic Medicine - The Scarf

Zachary G. Jacobs, MD

doi : 10.7326/G20-0108

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Annals Graphic Medicine - Wanted: All COVID-19 Variants

Oscar Li, BS

doi : 10.7326/G21-0048

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Annals for Educators - September 2021

Christine Laine, MD, MPH

doi : 10.7326/AWED202109210

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Annals for Hospitalists Inpatient Notes - Palliative Care Consultation—What a Hospitalist Should Know

Timothy C. Poore, MD , Steven Z. Pantilat, MD

doi : 10.7326/M21-3118

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Summary for Patients: Treating Pain in Adults With Sickle Cell Disease in an Infusion Center Versus the Emergency Department

doi : 10.7326/P21-0005

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Summary for Patients: Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Death

doi : 10.7326/P21-0006

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