One-year access to more than 500 world journals available in the system
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MRI Metrics of Cerebral Endothelial Cell–Derived Exosomes for the Treatment of Cognitive Dysfunction Induced in Aging Rats Subjected to Type 2 Diabetes
Guangliang Ding; Lian Li; Li Zhang; Michael Chopp; Esmaeil Davoodi-Bojd; Qingjiang Li; Chao Li; Min Wei; Zhenggang Zhang; Quan Jiang
doi : 10.2337/db21-0754
Canagliflozin Prevents Hyperglycemia-Associated Muscle Extracellular Matrix Accumulation and Improves the Adaptive Response to Aerobic Exercise
Tara L. MacDonald; Pattarawan Pattamaprapanont; Eileen M. Cooney; Roberto C. Nava; Joanna Mitri; Samar Hafida; Sarah J. Lessard
doi : 10.2337/db21-0934
Alteration of the Individual Metabolic Network of the Brain Based on Jensen-Shannon Divergence Similarity Estimation in Elderly Patients With Type 2 Diabetes Mellitus
Yu-Lin Li; Jia-Jia Wu; Jie Ma; Si-Si Li; Xin Xue; Dong Wei; Chun-Lei Shan; Xu-Yun Hua; Mou-Xiong Zheng; Jian-Guang Xu
doi : 10.2337/db21-0600
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle
Jeppe K. Larsen; Magnus R. Larsen; Jesper B. Birk; Dorte E. Steenberg; Janne R. Hingst; Kurt Højlund; Alexandra Chadt; Hadi Al-Hasani; Atul S. Deshmukh; Jørgen F.P. Wojtaszewski; Rasmus Kjøbsted
doi : 10.2337/db21-0855
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination
Yuguo Niu; Haizhou Jiang; Hanrui Yin; Fenfen Wang; Ronggui Hu; Xiaoming Hu; Bo Peng; Yousheng Shu; Zhigang Li; Shanghai Chen; Feifan Guo
doi : 10.2337/db21-0857
Sleep Disturbance and Changes in Energy Intake and Body Composition During Weight Loss in the POUNDS Lost Trial
Ang Li; Xiang Li; Tao Zhou; Hao Ma; Yoriko Heianza; Donald A. Williamson; Steven R. Smith; George A. Bray; Frank M. Sacks; Lu Qi
doi : 10.2337/db21-0699
Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones
Khyati Girdhar; Marion Soto; Qian Huang; Lucie Orliaguet; Carly Cederquist; Bharathi Sundaresh; Jiang Hu; Maximilian Figura; Amol Raisingani; Emanuel E. Canfora; Ercument Dirice; Shiho Fujisaka; Gijs H. Goossens; Ellen E. Blaak; Rohit N. Kulkarni; C. Ronald Kahn; Emrah Altindis
doi : 10.2337/db21-0382
YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells
Di Liu; Kevin Y. Yang; Vicken W. Chan; Wenchu Ye; Charing C.N. Chong; Chi Chiu Wang; Huating Wang; Bin Zhou; Kenneth K.Y. Cheng; Kathy O. Lui
doi : 10.2337/db21-0695
The Essential Role of Pancreatic α-Cells in Maternal Metabolic Adaptation to Pregnancy
Liping Qiao; Sarah Saget; Cindy Lu; Tianyi Zang; Brianna Dzyuba; William W. Hay, Jr.; Jianhua Shao
doi : 10.2337/db21-0923
Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation
Sharon Baumel-Alterzon; Liora S. Katz; Gabriel Brill; Clairete Jean-Pierre; Yansui Li; Isabelle Tse; Shyam Biswal; Adolfo Garcia-Ocaña; Donald K. Scott
doi : 10.2337/db21-0581
T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope
Yi Jing; Yuelin Kong; John McGinty; Gabriele Blahnik-Fagan; Thomas Lee; Stephanie Orozco-Figueroa; Matthew L. Bettini; Eddie A. James; Maria Bettini
doi : 10.2337/db21-0993
Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control
Chisayo Kozuka; Vissarion Efthymiou; Vicencia M. Sales; Liyuan Zhou; Soravis Osataphan; Yixing Yuchi; Jeremy Chimene-Weiss; Christopher Mulla; Elvira Isganaitis; Jessica Desmond; Suzuka Sanechika; Joji Kusuyama; Laurie Goodyear; Xu Shi; Robert E. Gerszten; Cristina Aguayo-Mazzucato; Priscila Carapeto; Silvania DaSilva Teixeira; Darleen Sandoval; Direna Alonso-Curbelo; Lei Wu; Jun Qi; Mary-Elizabeth Patti
doi : 10.2337/db21-0574
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum–Mitochondria Contact and Mitophagy in Diabetic Nephropathy
Chenrui Li; Li Li; Ming Yang; Jinfei Yang; Chanyue Zhao; Yachun Han; Hao Zhao; Na Jiang; Ling Wei; Ying Xiao; Yan Liu; Xiaofen Xiong; Yiyun Xi; Shilu Luo; Fei Deng; Wei Chen; Shuguang Yuan; Xuejing Zhu; Li Xiao; Lin Sun
doi : 10.2337/db21-0983
Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice
William P. Miller; Allyson L. Toro; Siddharth Sunilkumar; Shaunaci A. Stevens; Ashley M. VanCleave; David L. Williamson; Alistair J. Barber; Michael D. Dennis
doi : 10.2337/db21-0853
N-Hydroxyethyl-1-Deoxynojirimycin (Miglitol) Restores the Counterregulatory Response to Hypoglycemia Following Antecedent Hypoglycemia
Anne J. Jokiaho; Matthew Winchester; Casey M. Donovan
doi : 10.2337/db21-0859
pdx1 Knockout Leads to a Diabetic Nephropathy– Like Phenotype in Zebrafish and Identifies Phosphatidylethanolamine as Metabolite Promoting Early Diabetic Kidney Damage
Lucas M. Wiggenhauser; Lena Metzger; Katrin Bennewitz; Silas Soleymani; Mike Boger; Christoph T. Tabler; Ingrid Hausser; Carsten Sticht; Paulus Wohlfart; Nadine Volk; Elena Heidenreich; Michael Buettner; Hans-Peter Hammes; Jens Kroll
doi : 10.2337/db21-0645
Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age
Fabiola Marino; Mariangela Scalise; Nadia Salerno; Luca Salerno; Claudia Molinaro; Donato Cappetta; Michele Torella; Marta Greco; Daniela Foti; Ferdinando C. Sasso; Pasquale Mastroroberto; Antonella De Angelis; Georgina M. Ellison-Hughes; Maurilio Sampaolesi; Marcello Rota; Francesco Rossi; Konrad Urbanek; Bernardo Nadal-Ginard; Daniele Torella; Eleonora Cianflone
doi : 10.2337/db21-0536
Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-Mediated eNOS Monomerization
Lei Zhao; Cheng-Lin Zhang; Lei He; Qinghua Chen; Limei Liu; Lijing Kang; Jian Liu; Jiang-Yun Luo; Lingshan Gou; Dan Qu; Wencong Song; Chi Wai Lau; Ho Ko; Vincent C.T. Mok; Xiao Yu Tian; Li Wang; Yu Huang
doi : 10.2337/db21-0660
GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue
Jonathan E. Campbell; Jacqueline L. Beaudry; Berit Svendsen; Laurie L. Baggio; Andrew N. Gordon; John R. Ussher; Chi Kin Wong; Fiona M. Gribble; David A. D’Alessio; Frank Reimann; Daniel J. Drucker
doi : 10.2337/db21-1166
Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY
Thomas W. Laver; Matthew N. Wakeling; Olivia Knox; Kevin Colclough; Caroline F. Wright; Sian Ellard; Andrew T. Hattersley; Michael N. Weedon; Kashyap A. Patel
doi : 10.2337/db21-0844
Systematic Heritability and Heritability Enrichment Analysis for Diabetes Complications in UK Biobank and ACCORD Studies
Juhyun Kim; Aubrey Jensen; Seyoon Ko; Sridharan Raghavan; Lawrence S. Phillips; Adriana Hung; Yan Sun; Hua Zhou; Peter Reaven; Jin J. Zhou
doi : 10.2337/db21-0839
Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy
Yashika Rustagi; Ahmed S. Abouhashem; Priyanka Verma; Sumit S. Verma; Edward Hernandez; Sheng Liu; Manishekhar Kumar; Poornachander R. Guda; Rajneesh Srivastava; Sujit K. Mohanty; Sedat Kacar; Sanskruti Mahajan; Kristen E. Wanczyk; Savita Khanna; Michael P. Murphy; Gayle M. Gordillo; Sashwati Roy; Jun Wan; Chandan K. Sen; Kanhaiya Singh
doi : 10.2337/db21-0830
