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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases
William T. Cefalu; Dana K. Andersen; Guillermo Arreaza-RubÃn; Christopher L. Pin; Sheryl Sato; C. Bruce Verchere; Minna Woo; Norman D. Rosenblum; on behalf of the symposium planning committee, moderators, and speakers
doi : 10.2337/db21-0777
Aging Leukocytes and the Inflammatory Microenvironment of the Adipose Tissue
Korbyn J.V. Dahlquist; Christina D. Camell
doi : 10.2337/dbi21-0013
Hepatic CPT1A Facilitates Liver–Adipose Cross Talk via Induction of FGF21 in Mice
Wei Sun; Tao Nie; Kuai Li; Wenjie Wu; Qiaoyun Long; Tianshi Feng; Liufeng Mao; Yuan Gao; Qing Liu; Xuefei Gao; Dewei Ye; Kaixuan Yan; Ping Gu; Yong Xu; Xuemei Zhao; Kang Chen; Kerry Martin Loomes; Shaoqiang Lin; Donghai Wu; Xiaoyan Hui
doi : 10.2337/db21-0363
JMJD8 Is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance
Dongjoo You; Byung Chul Jung; Sneha Damal Villivalam; Hee-Woong Lim; Sona Kang
doi : 10.2337/db21-0596
Hepatic p38 Activation Modulates Systemic Metabolism Through FGF21-Mediated Interorgan Communication
Wei Liu; Chao Sun; Ying Yan; Hongchao Cao; Zhoumin Niu; Siyi Shen; Shengnan Liu; Yuting Wu; Yan Li; Lijian Hui; Yuying Li; Lin Zhao; Cheng Hu; Qiurong Ding; Jingjing Jiang; Hao Ying
doi : 10.2337/db21-0240
Glucagon Clearance Is Preserved in Type 2 Diabetes
Magnus F.G. Grøndahl; Asger B. Lund; Jonatan I. Bagger; Tonny S. Petersen; Nicolai J. Wewer Albrechtsen; Jens J. Holst; Tina Vilsbøll; Mikkel B. Christensen; Filip K. Knop
doi : 10.2337/db21-0024
EET Analog Treatment Improves Insulin Signaling in a Genetic Mouse Model of Insulin Resistance
Kakali Ghoshal; Xiyue Li; Dungeng Peng; John R. Falck; Raghunath Reddy Anugu; Manuel Chiusa; John M. Stafford; David H. Wasserman; Roy Zent; James M. Luther; Ambra Pozzi
doi : 10.2337/db21-0298
Active Brown Adipose Tissue Is Associated With a Healthier Metabolic Phenotype in Obesity
Carsten T. Herz; Oana C. Kulterer; Marlene Prager; Christoph Schmöltzer; Felix B. Langer; Gerhard Prager; Rodrig Marculescu; Alexandra Kautzky-Willer; Marcus Hacker; Alexander R. Haug; Florian W. Kiefer
doi : 10.2337/db21-0475
Specific Deletion of CASK in Pancreatic β-Cells Affects Glucose Homeostasis and Improves Insulin Sensitivity in Obese Mice by Reducing Hyperinsulinemia
Xingjing Liu; Peng Sun; Qingzhao Yuan; Jinyang Xie; Ting Xiao; Kai Zhang; Xiu Chen; Yao Wang; Li Yuan; Xiao Han
doi : 10.2337/db20-1208
Impact of Proinflammatory Cytokines on Alternative Splicing Patterns in Human Islets
Wenting Wu; Farooq Syed; Edward Simpson; Chih-Chun Lee; Jing Liu; Garrick Chang; Chuanpeng Dong; Clayton Seitz; Decio L. Eizirik; Raghavendra G. Mirmira; Yunlong Liu; Carmella Evans-Molina
doi : 10.2337/db20-0847
Relationship Between Insulin Secretion and Insulin Sensitivity and Its Role in Development of Type 2 Diabetes: Beyond the Disposition Index
Elsa Vazquez Arreola; Robert L. Hanson; Clifton Bogardus; William C. Knowler
doi : 10.2337/db21-0416
Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease
Nehaben A. Gujarati; Alexandra R. Leonardo; Jessica M. Vasquez; Yiqing Guo; Bismark O. Frimpong; Elbek Fozilov; Monica P. Revelo; Ilse S. Daehn; John C. He; Daniel Bogenhagen; Sandeep K. Mallipattu
doi : 10.2337/db21-0316
Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes
Philippe P. Pagni; Jay Chaplin; Michael Wijaranakula; Johnna D. Wesley; Jaimie Granger; Justen Cracraft; Conor O’Brien; Nikole Perdue; Vijetha Kumar; Shangjin Li; Sowbarnika Sachithanantham Ratliff; Allie Roach; Ayesha Misquith; Chung-leung Chan; Ken Coppieters; Matthias von Herrath
doi : 10.2337/db21-0327
Erratum. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes 2021;70:996–1005
Shylaja Srinivasan; Ling Chen; Jennifer Todd; Jasmin Divers; Samuel Gidding; Steven Chernausek; Rose A. Gubitosi-Klug; Megan M. Kelsey; Rachana Shah; Mary Helen Black; Lynne E. Wagenknecht; Alisa Manning; Jason Flannick; Giuseppina Imperatore; Josep M. Mercader; Dana Dabelea; Jose C. Florez; on behalf of the ProDiGY Consortium
doi : 10.2337/db22-er01a
Erratum. SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans. Diabetes 2021;70:2364–2376
Harunobu Nishizaki; Osamu Matsuoka; Tomoya Kagawa; Akihiro Kobayashi; Masanori Watanabe; Yusuke Moritoh
doi : 10.2337/db22-er01b
The Women’s Leadership Gap in Diabetes: A Call for Equity and Excellence. Diabetes 2021;70:1623–1633
Gary Tse; Tong Liu; Leonardo Roever; Sharen Lee
doi : 10.2337/db21-0686
