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What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia?
Barbara E. Corkey; Jude T. Deeney; Matthew J. Merrins
doi : 10.2337/dbi21-0009
Annexin 1 Mimetic Ac2-26 Holds Promise for the Treatment of Diabetic Nephropathy
Yu Pan; Ming-Zhi Zhang; Raymond C. Harris
doi : 10.2337/dbi21-0030
Found in Translation: Novel Insights Into Type 1 Diabetes and β-Cell Biology
Holger A. Russ; Howard W. Davidson
doi : 10.2337/dbi21-0031
Type 2 Diabetes, Glycemia, and Brain Health: The Complexity of Causality
Velandai Srikanth
doi : 10.2337/dbi21-0018
Perirenal Fat and Chronic Kidney Disease in Patients With Diabetes
Leonardo Roever; Gary Tse; Giuseppe Biondi-Zoccai
doi : 10.2337/dbi21-0032
The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism Through the AMPK/PPARα/CPT1b Pathway
Liang Wu; Changjie Liu; Dong-Yuan Chang; Rui Zhan; Mingming Zhao; Sin Man Lam; Guanghou Shui; Ming-Hui Zhao; Lemin Zheng; Min Chen
doi : 10.2337/db21-0050
Prohibitin Inactivation in Adipocytes Results in Reduced Lipid Metabolism and Adaptive Thermogenesis Impairment
Zhanguo Gao; Alexes C. Daquinag; Cale Fussell; Amel Djehal; Laurent Désaubry; Mikhail G. Kolonin
doi : 10.2337/db21-0094
Mutations of NRG4 Contribute to the Pathogenesis of Nonalcoholic Fatty Liver Disease and Related Metabolic Disorders
Yangyang Li; Li Jin; Feng Jiang; Jing Yan; Yan Lu; Qing Yang; Yi Zhang; Hong Zhang; Hairong Yu; Yuemei Zhang; Zhen He; Rong Zhang; Jianjun Yang; Cheng Hu
doi : 10.2337/db21-0064
Subcutaneous Adipose Tissue Metabolic Function and Insulin Sensitivity in People With Obesity
Han-Chow E. Koh; Stephan van Vliet; Terri A. Pietka; Gretchen A. Meyer; Babak Razani; Richard Laforest; Robert J. Gropler; Bettina Mittendorfer
doi : 10.2337/db21-0160
Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons
Gabriela Farias Quipildor; Kai Mao; Pedro J. Beltran; Nir Barzilai; Derek M. Huffman
doi : 10.2337/db21-0028
The Choline Metabolite TMAO Inhibits NETosis and Promotes Placental Development in GDM of Humans and Mice
Xiaojing Lin; Yunqi Zhang; Xiaoling He; Yan Chen; Nan Chen; Juncheng Liu; Miaoran Wang; Yue Li; Hong Yang; Lei Fan; Yi Hou; Jibin Li; Chaodong Wu; Hongbo Qi; Hua Zhang; Xiaoqiu Xiao
doi : 10.2337/db21-0188
Chronic Antidiabetic Actions of Leptin: Evidence From Parabiosis Studies for a CNS-Derived Circulating Antidiabetic Factor
Alexandre A. da Silva; John E. Hall; Xuemei Dai; Zhen Wang; Mateus C. Salgado; Jussara M. do Carmo
doi : 10.2337/db21-0126
Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic β-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression
Huimin Lu; Rui Guo; Yunjin Zhang; Shenghan Su; Qingrui Zhao; Yue Yu; Hongbo Shi; Haoran Sun; Yongjian Zhang; Shenglong Li; Dan Shi; Xia Chu; Changhao Sun
doi : 10.2337/db20-1079
Sleeve Gastrectomy Suppresses Hepatic Glucose Production and Increases Hepatic Insulin Clearance Independent of Weight Loss
Rachel Ben-Haroush Schyr; Abbas Al-Kurd; Botros Moalem; Anna Permyakova; Hadar Israeli; Aya Bardugo; Yhara Arad; Liron Hefetz; Michael Bergel; Arnon Haran; Shahar Azar; Itia Magenheim; Joseph Tam; Ronit Grinbaum; Danny Ben-Zvi
doi : 10.2337/db21-0251
Long RNA Sequencing and Ribosome Profiling of Inflamed β-Cells Reveal an Extensive Translatome Landscape
Sofia Thomaidou; Roderick C. Slieker; Arno R. van der Slik; Jasper Boom; Flip Mulder; Amadeo Munoz-Garcia; Leen M. ‘t Hart; Bobby Koeleman; Françoise Carlotti; Rob C. Hoeben; Bart O. Roep; Hailiang Mei; Arnaud Zaldumbide
doi : 10.2337/db20-1122
Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank
Victoria Garfield; Aliki-Eleni Farmaki; Ghazaleh Fatemifar; Sophie V. Eastwood; Rohini Mathur; Christopher T. Rentsch; Spiros Denaxas; Krishnan Bhaskaran; Liam Smeeth; Nish Chaturvedi
doi : 10.2337/db20-0895
Perirenal Fat Thickness Is Significantly Associated With the Risk for Development of Chronic Kidney Disease in Patients With Diabetes
Xiangjun Chen; Yun Mao; Jinbo Hu; Shichao Han; Lilin Gong; Ting Luo; Shumin Yang; Hua Qing; Yue Wang; Zhipeng Du; Mei Mei; Li Zheng; Xinlu Lv; Ying Tang; Qinying Zhao; Yangmei Zhou; John Cijiang He; Qifu Li; Zhihong Wang
doi : 10.2337/db20-1031
Insulin Resistance in Skeletal Muscle Selectively Protects the Heart in Response to Metabolic Stress
Dandan Jia; Jun Zhang; Xueling Liu; John-Paul Andersen; Zhenjun Tian; Jia Nie; Yuguang Shi
doi : 10.2337/db20-1212
Intraglomerular Dysfunction Predicts Kidney Failure in Type 2 Diabetes
Pierre J. Saulnier; Helen C. Looker; Michael Mauer; Behzad Najafian; Elise Gand; Stephanie Ragot; Robert G. Nelson; Petter Bjornstad
doi : 10.2337/db21-0154
Contributions of Sodium-Hydrogen Exchanger 1 and Mitogen-Activated Protein Kinases to Enhanced Retinal Venular Constriction to Endothelin-1 in Diabetes
Yen-Lin Chen; Yi Ren; Robert H. Rosa, Jr.; Lih Kuo; Travis W. Hein
doi : 10.2337/db20-0889
SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans
Harunobu Nishizaki; Osamu Matsuoka; Tomoya Kagawa; Akihiro Kobayashi; Masanori Watanabe; Yusuke Moritoh
doi : 10.2337/db21-0451
Profile of Podocyte Translatome During Development of Type 2 and Type 1 Diabetic Nephropathy Using Podocyte-Specific TRAP mRNA RNA-seq
Yinqiu Wang; Aolei Niu; Yu Pan; Shirong Cao; Andrew S. Terker; Suwan Wang; Xiaofeng Fan; Cynthia L. Toth; Marisol A. Ramirez Solano; Danielle L. Michell; Danielle Contreras; Ryan M. Allen; Wanying Zhu; Quanhu Sheng; Agnes B. Fogo; Kasey C. Vickers; Ming-Zhi Zhang; Raymond C. Harris
doi : 10.2337/db21-0110
The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes
Emma H. Dahlström; Jani Saksi; Carol Forsblom; Nicoline Uglebjerg; Nina Mars; Lena M. Thorn; Valma Harjutsalo; Peter Rossing; Tarunveer S. Ahluwalia; Perttu J. Lindsberg; Niina Sandholm; Per-Henrik Groop; on behalf of the FinnDiane Study Group
doi : 10.2337/db21-0056
Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes
Emma Nilsson; Magdalena Vavakova; Alexander Perfilyev; Johanna Säll; Per-Anders Jansson; Pernille Poulsen; Jonathan Lou S. Esguerra; Lena Eliasson; Allan Vaag; Olga Göransson; Charlotte Ling
doi : 10.2337/db20-0324
Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes
Diane Yang; Sanjeet Patel; Wojciech J. Szlachcic; Jolanta Chmielowiec; Diane Scaduto; Nagireddy Putluri; Arun Sreekumar; James Suliburk; Michael Metzker; Ashok Balasubramanyam; Malgorzata Borowiak
doi : 10.2337/db20-1293
