One-year access to more than 500 world journals available in the system
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From Pancreatic β-Cell Gene Networks to Novel Therapies for Type 1 Diabetes
Decio L. Eizirik; Florian Szymczak; Maria Inês Alvelos; Frank Martin
doi : 10.2337/dbi20-0046
Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance
Kierstin L. Webster; Lev Becker
doi : 10.2337/dbi21-0017
The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity
Makoto Fukuda
doi : 10.2337/dbi21-0001
GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Based Therapies in Treating Metabolic Disorders
Ricardo J. Samms; Kyle W. Sloop; Fiona M. Gribble; Frank Reimann; Alice E. Adriaenssens
doi : 10.2337/dbi21-0002
Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Mette Q. Ludwig; Petar V. Todorov; Kristoffer L. Egerod; David P. Olson; Tune H. Pers
doi : 10.2337/dbi21-0003
The Role of GIP in the Regulation of GLP-1 Satiety and Nausea
Matthew R. Hayes; Tito Borner; Bart C. De Jonghe
doi : 10.2337/dbi21-0004
Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2
Callie A.S. Corsa; Carolyn M. Walsh; Devika P. Bagchi; Maria C. Foss Freitas; Ziru Li; Julie Hardij; Katrina Granger; Hiroyuki Mori; Rebecca L. Schill; Kenneth T. Lewis; Jessica N. Maung; Ruth D. Azaria; Amy E. Rothberg; Elif A. Oral; Ormond A. MacDougald
doi : 10.2337/db20-1001
Insulin Directly Regulates the Circadian Clock in Adipose Tissue
Neta Tuvia; Olga Pivovarova-Ramich; Veronica Murahovschi; Sarah Lück; Astrid Grudziecki; Anne-Catrin Ost; Michael Kruse; Victoria J. Nikiforova; Martin Osterhoff; Pascal Gottmann; Özlem Gögebakan; Carsten Sticht; Norbert Gretz; Michael Schupp; Annette Schürmann; Natalia Rudovich; Andreas F.H. Pfeiffer; Achim Kramer
doi : 10.2337/db20-0910
TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue
Cheoljun Choi; Yeonho Son; Jinyoung Kim; Yoon Keun Cho; Abhirup Saha; Minsu Kim; Hyeonyeong Im; Kyungmin Kim; Juhyeong Han; Jung Weon Lee; Je Kyung Seong; Yun-Hee Lee
doi : 10.2337/db21-0145
HIV-1 Viral Protein R Couples Metabolic Inflexibility With White Adipose Tissue Thermogenesis
Neeti Agarwal; Dinakar Iyer; Pradip Saha; Aaron R. Cox; Yan Xia; Netanya S. Utay; Anoma Somasundaram; Ulrich Schubert; Jordan E. Lake; Sean M. Hartig; Ashok Balasubramanyam
doi : 10.2337/db20-0888
STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity
Anaïs Schaschkow; Lokman Pang; Valerie Vandenbempt; Bernat Elvira; Sara A. Litwak; Beata Vekeriotaite; Elisa Maillard; Marjorie Vermeersch; Flavia M.M. Paula; Michel Pinget; David Perez-Morga; Daniel J. Gough; Esteban N. Gurzov
doi : 10.2337/db20-1222
Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages
Omar Sharif; Julia Stefanie Brunner; Ana Korosec; Rui Martins; Alexander Jais; Berend Snijder; Andrea Vogel; Michael Caldera; Anastasiya Hladik; Karin Lakovits; Simona Saluzzo; Benedikta Boehm; Anna-Dorothea Gorki; Ildiko Mesteri; Josefine Lindroos-Christensen; Katharina Tillmann; Dagmar Stoiber; Jörg Menche; Gernot Schabbauer; Martin Bilban; Giulio Superti-Furga; Harald Esterbauer; Sylvia Knapp
doi : 10.2337/db20-0572
The Anna Karenina Model of β-Cell Maturation in Development and Their Dedifferentiation in Type 1 and Type 2 Diabetes
Sutichot D. Nimkulrat; Matthew N. Bernstein; Zijian Ni; Jared Brown; Christina Kendziorski; Barak Blum
doi : 10.2337/db21-0211
Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases
Emelyne Lécuyer; Tiphaine Le Roy; Aurélie Gestin; Amélie Lacombe; Catherine Philippe; Maharajah Ponnaiah; Jean-Baptiste Huré; Magali Fradet; Farid Ichou; Samira Boudebbouze; Thierry Huby; Emmanuel Gautier; Moez Rhimi; Emmanuelle Maguin; Nathalie Kapel; Philippe Gérard; Nicolas Venteclef; Michèle Garlatti; Benoit Chassaing; Philippe Lesnik
doi : 10.2337/db20-1177
Deletion of the Feeding-Induced Hepatokine TSK Ameliorates the Melanocortin Obesity Syndrome
Qiuyu Wang; Peng Zhang; Isin Cakir; Lin Mi; Roger D. Cone; Jiandie D. Lin
doi : 10.2337/db21-0161
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study
Andrea Tura; Eleonora Grespan; Christian S. Göbl; Robert W. Koivula; Paul W. Franks; Ewan R. Pearson; Mark Walker; Ian M. Forgie; Giuseppe N. Giordano; Imre Pavo; Hartmut Ruetten; Emmanouil T. Dermitzakis; Mark I. McCarthy; Oluf Pedersen; Jochen M. Schwenk; Jerzy Adamski; Federico De Masi; Konstantinos D. Tsirigos; Søren Brunak; Ana Viñuela; Anubha Mahajan; Timothy J. McDonald; Tarja Kokkola; Jagadish Vangipurapu; Henna Cederberg; Markku Laakso; Femke Rutters; Petra J.M. Elders; Anitra D.M. Koopman; Joline W. Beulens; Martin Ridderstråle; Tue H. Hansen; Kristine H. Allin; Torben Hansen; Henrik Vestergaard; Andrea Mari; IMI DIRECT Consortium
doi : 10.2337/db21-0227
Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1
Zhen Guo; Yixuan Zhang; Chang Liu; Ji Youn Youn; Hua Cai
doi : 10.2337/db20-0591
LTB4-Driven Inflammation and Increased Expression of ALOX5/ACE2 During Severe COVID-19 in Individuals With Diabetes
Icaro Bonyek-Silva; Antônio Fernando Araújo Machado; Thiago Cerqueira-Silva; Sara Nunes; Márcio Rivison Silva Cruz; Jéssica Silva; Reinan Lima Santos; Aldina Barral; Pablo Rafael Silveira Oliveira; Ricardo Khouri; C. Henrique Serezani; Cláudia Brodskyn; Juliana Ribeiro Caldas; Manoel Barral-Netto; Viviane Boaventura; Natalia Machado Tavares
doi : 10.2337/db20-1260
Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes
Dasan Mary Cibi; Reddemma Sandireddy; Hanumakumar Bogireddi; Nicole Tee; Siti Aishah Binte Abdul Ghani; Brijesh K. Singh; Nigel Mackman; Manvendra K. Singh; Anamika Singh
doi : 10.2337/db20-0719
Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease
Tatsuhiko Azegami; Takashin Nakayama; Kaori Hayashi; Akihito Hishikawa; Norifumi Yoshimoto; Ran Nakamichi; Hiroshi Itoh
doi : 10.2337/db20-1257
Erratum. NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8+ T-Cell Numbers. Diabetes 2020;69:1749–1762
Andrew P. Trembath; Kelsey L. Krausz; Neekun Sharma; Ivan C. Gerling; Clayton E. Mathews; Mary A. Markiewicz
doi : 10.2337/db21-er09a
Erratum. A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577–588
Chenghui Yan; Xiaoxiang Tian; Jiayin Li; Dan Liu; Ding Ye; Zhonglin Xie; Yaling Han; Ming-Hui Zou
doi : 10.2337/db21-er09b
A Hundred Years of Insulin Innovation: When Science Meets Technology
Thomas Kjeldsen; Peter Kurtzhals
doi : 10.2337/db21-0430
