Nature Biotechnology




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tRNA therapeutics burst onto startup scene

Elie Dolgin 

doi : 10.1038/s41587-022-01252-y

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Bio-leather gears up to wow fashion industry

Emily Waltz 

doi : 10.1038/s41587-022-01258-6

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Bilateral China–Brazil ties over agbiotech

doi : 10.1038/s41587-022-01265-7

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Diabetes cell therapies take evasive action

Elie Dolgin 

doi : 10.1038/s41587-022-01246-w

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So you want to start a biotech company

Sadhana Chitale, Colm Lawler & Arthur KlausnerÂ

doi : 10.1038/s41587-022-01239-9

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Contractual solutions to overcome drug scarcity during pandemics and epidemics

Sapna Kumar & Ana Santos RutschmanÂ

doi : 10.1038/s41587-022-01241-1

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Sustainable manufacturing with synthetic biology

Corinne D. Scown & Jay D. KeaslingÂ

doi : 10.1038/s41587-022-01248-8

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Spatial components of molecular tissue biology

Giovanni Palla, David S. Fischer, Aviv Regev & Fabian J. TheisÂ

doi : 10.1038/s41587-021-01182-1

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Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

J. Loske, J. Röhmel, S. Lukassen, S. Stricker, V. G. Magalhães, J. Liebig, R. L. Chua, L. Thürmann, M. Messingschlager, A. Seegebarth, B. Timmerman

doi : 10.1038/s41587-021-01037-9

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Direct targeting of amplified gene loci for proapoptotic anticancer therapy

Meetu Kaushik Tiwari, Daniel A. Colon-Rios, Hemanta C. Rao Tumu, Yanfeng Liu, Elias Quijano, Adam Krysztofiak, Cynthia Chan, Eric Song, Demetrios T. B

doi : 10.1038/s41587-021-01057-5

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Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

Fungmin Eric Liew, Robert Nogle, Tanus Abdalla, Blake J. Rasor, Christina Canter, Rasmus O. Jensen, Lan Wang, Jonathan Strutz, Payal Chirania, Sashini

doi : 10.1038/s41587-021-01195-w

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Cell segmentation in imaging-based spatial transcriptomics

Viktor Petukhov, Rosalind J. Xu, Ruslan A. Soldatov, Paolo Cadinu, Konstantin Khodosevich, Jeffrey R. Moffitt & Peter V. KharchenkoÂ

doi : 10.1038/s41587-021-01044-w

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Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics

Yakir A. Reshef, Laurie Rumker, Joyce B. Kang, Aparna Nathan, Ilya Korsunsky, Samira Asgari, Megan B. Murray, D. Branch Moody & Soumya RaychaudhuriÂ

doi : 10.1038/s41587-021-01066-4

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Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing

Lixue Shi, Mian Wei, Yupeng Miao, Naixin Qian, Lingyan Shi, Ruth A. Singer, Richard K. P. Benninger & Wei MinÂ

doi : 10.1038/s41587-021-01041-z

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Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC

Evgenij Fiskin, Caleb A. Lareau, Leif S. Ludwig, Gökcen Eraslan, Feimei Liu, Aaron M. Ring, Ramnik J. Xavier & Aviv RegevÂ

doi : 10.1038/s41587-021-01065-5

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High-throughput functional characterization of protein phosphorylation sites in yeast

Cristina Viéitez, Bede P. Busby, David Ochoa, André Mateus, Danish Memon, Marco Galardini, Umut Yildiz, Matteo Trovato, Areeb Jawed, Alexander G. Ge

doi : 10.1038/s41587-021-01051-x

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Functional single-cell genomics of human cytomegalovirus infection

Marco Y. Hein & Jonathan S. WeissmanÂ

doi : 10.1038/s41587-021-01059-3

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Engineered pegRNAs improve prime editing efficiency

James W. Nelson, Peyton B. Randolph, Simon P. Shen, Kelcee A. Everette, Peter J. Chen, Andrew V. Anzalone, Meirui An, Gregory A. Newby, Jonathan C. Ch

doi : 10.1038/s41587-021-01039-7

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High-confidence structural annotation of metabolites absent from spectral libraries

Martin A. Hoffmann, Louis-Félix Nothias, Marcus Ludwig, Markus Fleischauer, Emily C. Gentry, Michael Witting, Pieter C. Dorrestein, Kai Dührkop & Se

doi : 10.1038/s41587-021-01045-9

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Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

Kumar Gaurav, Sanu Arora, Paula Silva, Javier Sánchez-Martín, Richard Horsnell, Liangliang Gao, Gurcharn S. Brar, Victoria Widrig, W. John Raupp, Na

doi : 10.1038/s41587-021-01058-4

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Author Correction: Engineered pegRNAs improve prime editing efficiency

James W. Nelson, Peyton B. Randolph, Simon P. Shen, Kelcee A. Everette, Peter J. Chen, Andrew V. Anzalone, Meirui An, Gregory A. Newby, Jonathan C. Ch

doi : 10.1038/s41587-021-01175-0

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Author Correction: Multiscale and integrative single-cell Hi-C analysis with Higashi

Ruochi Zhang, Tianming Zhou & Jian MaÂ

doi : 10.1038/s41587-022-01263-9

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Integrating innovation as a core objective in medical training

Okechi Boms, Zhuo Shi, Nathan Mallipeddi, Janice J. Chung, William H. Marks, David C. Whitehead & Marc D. SucciÂ

doi : 10.1038/s41587-022-01253-x

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