J. Guckian C. Cotter M. Charalambides N. Kibbi
doi : 10.1111/bjd.19754
Volume 184, Issue 4, April 2021, Pages: 585-586
V. Eleftheriadou
doi : 10.1111/bjd.19535
Volume 184, Issue 4, April 2021, Pages: 587
K. Capozza
doi : 10.1111/bjd.19545
Volume 184, Issue 4, April 2021, Pages: 587-588
M.C. Johnson C.E. Heron S.R. Feldman
doi : 10.1111/bjd.19537
Volume 184, Issue 4, April 2021, Pages: 588-589
R. Patalay
doi : 10.1111/bjd.19571
Volume 184, Issue 4, April 2021, Pages: 590
X. Wortsman
doi : 10.1111/bjd.19433
Volume 184, Issue 4, April 2021, Pages: 591-592
C. Guttmann?Gruber J. Pi??n Hofbauer
doi : 10.1111/bjd.19607
Volume 184, Issue 4, April 2021, Pages: 592-593
D.J. Tobin
doi : 10.1111/bjd.19697
Volume 184, Issue 4, April 2021, Pages: 593
P. Porcu N. Nikbakht
doi : 10.1111/bjd.19763
Volume 184, Issue 4, April 2021, Pages: 594-595
R.R. van den Bos
doi : 10.1111/bjd.19567
Volume 184, Issue 4, April 2021, Pages: 595
J.Y.W. Lee J.A. McGrath
doi : 10.1111/bjd.19342
Volume 184, Issue 4, April 2021, Pages: 596-605
The desmosome is a type of intercellular junction found in epithelial cells, cardiomyocytes and other specialized cell types. Composed of a network of transmembranous cadherins and intracellular armadillo, plakin and other proteins, desmosomes contribute to cell–cell adhesion, signalling, development and differentiation.
F.P.?C. Chiu B.J. Doolan J.A. McGrath A. Onoufriadis
doi : 10.1111/bjd.19384
Volume 184, Issue 4, April 2021, Pages: 606-616
Discovering the genetic basis of inherited skin diseases is fundamental to improving diagnostic accuracy and genetic counselling. In the 1990s and 2000s, genetic linkage and candidate gene approaches led to the molecular characterization of several dozen genodermatoses, but over the past decade the advent of next?generation sequencing (NGS) technologies has accelerated diagnostic discovery and precision.
A. Lechner J. Kottner S. Coleman D. Muir D. Beeckman W. Chaboyer J. Cuddigan Z. Moore C. Rutherford J. Schmitt J. Nixon K. Balzer
doi : 10.1111/bjd.19304
Volume 184, Issue 4, April 2021, Pages: 617-626
In order to overcome inconsistencies in the reporting of outcomes in clinical trials, core outcome sets (COSs) have been developed in many clinical areas and the awareness of this concept is growing steadily. The Outcomes for Pressure Ulcer Trials (OUTPUTs) project aims to improve the quality of evidence from pressure ulcer prevention trials by developing a COS.
E. Teasdale I. Muller K. Sivyer D. Ghio K. Greenwell S. Wilczynska A. Roberts M.J. Ridd N. Francis L. Yardley K.S. Thomas M. Santer
doi : 10.1111/bjd.19299
Volume 184, Issue 4, April 2021, Pages: 627-637
The number of qualitative studies on eczema has increased rapidly in recent years. Systematically reviewing these can provide greater understandings of people’s perceptions of eczema and eczema treatments.
I.S. Malhi Z.Z.N. Yiu
doi : 10.1111/bjd.19502
Volume 184, Issue 4, April 2021, Pages: 638-639
A. Blauvelt C. Paul P. van de Kerkhof R.B. Warren A.B. Gottlieb R.G. Langley F. Brock C. Arendt M. Boehnlein M. Lebwohl K. Reich
doi : 10.1111/bjd.19314
Volume 184, Issue 4, April 2021, Pages: 640-651
Certolizumab pegol (CZP) is an Fc?free, PEGylated anti?tumour necrosis factor biologic.
K.B. Gordon R.B. Warren A.B. Gottlieb A. Blauvelt D. Thaçi C. Leonardi Y. Poulin M. Boehnlein F. Brock C. Ecoffet K. Reich
doi : 10.1111/bjd.19393
Volume 184, Issue 4, April 2021, Pages: 652-626
Certolizumab pegol (CZP) is an Fc?free, PEGylated anti?tumour necrosis factor biologic.
W. Woliner–van der Weg M. Peppelman Y.S. Elshot M.B. Visch M.B. Crijns H.A.C. Alkemade E.M. Bronkhorst E. Adang A. Amir M.J.P. Gerritsen P.E.J. van Erp S.F.K. Lubeek
doi : 10.1111/bjd.19381
Volume 184, Issue 4, April 2021, Pages: 663-671
Reflectance confocal microscopy (RCM) is a noninvasive method for skin assessment, allowing entire lesion evaluation up to the papillary dermis. RCM is a potentially attractive alternative to punch biopsy (PB) in basal cell carcinoma (BCC).
J.H. Alfonso J.I. Martinsen E. Weiderpass E. Pukkala K. Kj?rheim L. Tryggvadottir E Lynge
doi : 10.1111/bjd.19379
Volume 184, Issue 4, April 2021, Pages: 672-680
The age?adjusted incidence of cutaneous melanoma (CM) in the Nordic countries has increased during the last 60 years. Few prospective population?based studies have estimated the occupational variation in CM risk over time.
J.S. Kirby B. Hereford L. Thorlacius B. Villumsen J.R. Ingram A. Garg M. Butt S. Esmann T. King J. Tan G.B.E. Jemec
doi : 10.1111/bjd.19344
Volume 184, Issue 4, April 2021, Pages: 681-687
Hidradenitis suppurativa (HS) is a chronic inflammatory disease. The HS core outcome set calls for a patient global assessment (PtGA).
D. Grand J.W. Frew K. Navrazhina J.G. Krueger
doi : 10.1111/bjd.19343
Volume 184, Issue 4, April 2021, Pages: 688-696
There is a need for valid and reliable biomarkers in hidradenitis suppurativa (HS) for diagnosis and disease activity monitoring. Imaging?based biomarkers have the potential to fulfil this unmet need but no evaluation of analytical or clinical validity has yet been undertaken.
J.H.S. Dayal S.M. Mason J.C. Salas?Alanis J.A. McGrath R.G. Taylor J.E. Mellerio K. Blyth A.P. South G.J. Inman
doi : 10.1111/bjd.19421
Volume 184, Issue 4, April 2021, Pages: 697-708
Recessive dystrophic epidermolysis bullosa (RDEB) is associated with a high mortality rate due to the development of life?threatening, metastatic cutaneous squamous cell carcinoma (cSCC). Elevated transforming growth factor?beta (TGF??) signalling is implicated in cSCC development and progression in patients with RDEB.
A. Shapanis C. Lai S. Smith G. Coltart M. Sommerlad J. Schofield E. Parkinson P. Skipp E. Healy
doi : 10.1111/bjd.19485
Volume 184, Issue 4, April 2021, Pages: 709-721
Cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers capable of metastasizing. Proteomic analysis of cSCCs can provide insight into the biological processes responsible for metastasis, as well as future therapeutic targets and prognostic biomarkers.
P. Quaglino H.M. Prince R. Cowan M. Vermeer E. Papadavid M. Bagot O. Servitjie E. Berti E. Guenova R. Stadler C. Querfeld A.M. Busschots E. Hodak A. Patsatsi J. Sanches M. Maule J. Yoo M. Kevin P. Fava S. Ribero L. Zocchi M. Rubatto M.T. Fierro U. Wehkamp M. Marshalko C. Mitteldorf O. Akilov P. Ortiz?Romero T. Estrach L. Vakeva P.A. Enz M. Wobser M. Bayne C. Jonak M. Rubeta A. Forbes A. Bates M. Battistella R. Amel?Kashipaz B. Vydianath A. Combalia E. Georgiou E. Hauben E.K. Hong M. Jost R. Knobler I. Amitay?Laish D. Miyashiro J. Cury?Martins X. Martinez C. Muniesa H. Prag?Naveh A. Stratigos V. Nikolaou K. Quint C. Ram?Wolff K. Rieger R. Stranzenbach ?. Szepesi S. Alberti?Violetti E. Felicity L. Cerroni W. Kempf S. Whittaker R. Willemze Y. Kim J.J. Scarisbrick
doi : 10.1111/bjd.19252
Volume 184, Issue 4, April 2021, Pages: 722-730
The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study is a prospective analysis of an international database. Here we examine front?line treatments and quality of life (QoL) in patients with newly diagnosed mycosis fungoides (MF).
A. Durack S. Gran M.D. Gardiner A. Jain E. Craythorne C.M. Proby J. Marsden C.A. Harwood R.N. Matin the DFSP Collaborators
doi : 10.1111/bjd.19346
Volume 184, Issue 4, April 2021, Pages: 731-739
Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. Standard treatment in the UK is either wide local excision (WLE) or Mohs micrographic surgery (MMS). It is unclear which approach has the lower recurrence rate.
S. Burgin N.C. Dlova L.A. Goldsmith
doi : 10.1111/bjd.19663
Volume 184, Issue 4, April 2021, Pages: 740-741
J. Zhang W. Qin S. Hua M. Li Y. Tang Z. Yao
doi : 10.1111/bjd.19659
Volume 184, Issue 4, April 2021, Pages: 742-743
L.C.J. van Delft B.A.B. Essers P.J. Nelemans K. Mosterd N.W.J. Kelleners?Smeets
doi : 10.1111/bjd.19662
Volume 184, Issue 4, April 2021, Pages: 744-746
E. Charvet N. Kramkimel L. Chaplain A. Gantzer O. Kassem C. Longvert A. Blom N. Dupin S. Aractingi M. Hamon U. Zimmermann J.?F. Emile P. Sohier T. Sidibé P. Saiag E. Funck?Brentano
doi : 10.1111/bjd.19629
Volume 184, Issue 4, April 2021, Pages: 746-748
C.C. Zouboulis B. Readhead J.T. Dudley
doi : 10.1111/bjd.19627
Volume 184, Issue 4, April 2021, Pages: 748-750
J. Oh R.W. Lee H.R. Lee S.B. Lee H.J. Ju J. Park H.R. Park J.H. Park S?K. Hann A. Almurayshid J. Shin H.Y. Kang J.M. Bae S.H. Oh
doi : 10.1111/bjd.19661
Volume 184, Issue 4, April 2021, Pages: 750-753
R. L. Bruinsma K. Fajgenbaum Y. Yang M. del Mar Melendez?Gonzalez K. L. Mohlke Y. Li C. Sayed
doi : 10.1111/bjd.19664
Volume 184, Issue 4, April 2021, Pages: 753-754
A.V. Sears R.T. Woolf E. Gribaleva W. Abdelrahman S. Robbie B. Menon B. Kirkham C.H. Smith A.E. Pink
doi : 10.1111/bjd.19631
Volume 184, Issue 4, April 2021, Pages: 755-757
J. Groot C. Blegvad A.?M. Nybo Andersen C. Zachariae J.O. Jarl?v L. Skov
doi : 10.1111/bjd.19672
Volume 184, Issue 4, April 2021, Pages: 758-759
M.E.C. van Winden E.L.M. ter Haar J.M.M. Groenewoud P.C.M. van de Kerkhof E.M.G.J. de Jong S.F.K. Lubeek
doi : 10.1111/bjd.19665
Volume 184, Issue 4, April 2021, Pages: 759-762
M. Nakamura M. Obayashi M. Yoshimitsu H. Kato A. Morita
doi : 10.1111/bjd.19680
Volume 184, Issue 4, April 2021, Pages: 762-763
S. Ziaj F. Tseliou D. Datta R. A. Abbott
doi : 10.1111/bjd.19676
Volume 184, Issue 4, April 2021, Pages: 764-765
K. Reich C. Sorbe L. Griese J.L.K. Reich M. Augustin
doi : 10.1111/bjd.19690
Volume 184, Issue 4, April 2021, Pages: 765-767
S. Patel J.B. Cadwell W.C. Lambert
doi : 10.1111/bjd.19691
Volume 184, Issue 4, April 2021, Pages: 767-769
S.A. Veerabagu M.J. Lauth A. Obayomi M. Correa A.T. Murina
doi : 10.1111/bjd.19688
Volume 184, Issue 4, April 2021, Pages: 769-770
L.H. Frommherz C.M. Schempp C. Has
doi : 10.1111/bjd.19684
Volume 184, Issue 4, April 2021, Pages: 770-772
M.O. Machado J.D. Lu R. Brar J.S. Kirby A. Garg M.L. Lowes V. Piguet A. Alavi
doi : 10.1111/bjd.19686
Volume 184, Issue 4, April 2021, Pages: 772-774
M. Gill G. Pellacani J.M. Grant?Kels M. Ardig? C.?S.J. Chen S. Gonzalez P. Guitera C. Longo J. Malvehy O. Markowitz S. Puig H. Rabinovitz B.K. Rao A. Scope M. Ulrich
doi : 10.1111/bjd.19602
Volume 184, Issue 4, April 2021, Pages: 775-776
W. Woliner?van der Weg M. Peppelman P.E.J. van Erp S.F.K. Lubeek
doi : 10.1111/bjd.19605
Volume 184, Issue 4, April 2021, Pages: 776
doi : 10.1111/bjd.19859
Volume 184, Issue 4, April 2021, Pages: 777-785
R. Agrawal S. Tso E.A. Eltigani K.J. Busam S.M. Taibjee R.A. Carr
doi : 10.1111/bjd.19599
Volume 184, Issue 4, April 2021, Pages: e122
A. Bonifaz D. Fern?ndez?Samar A. Tirado?S?nchez D. V?zquez?Gonz?lez P. Mercadillo?Pérez
doi : 10.1111/bjd.19600
Volume 184, Issue 4, April 2021, Pages: e123-e124
A. Amrani A. Das
doi : 10.1111/bjd.19606
Volume 184, Issue 4, April 2021, Pages: e125
doi : 10.1111/bjd.19837
Volume 184, Issue 4, April 2021, Pages: e126
Dermatofibrosarcoma protuberans (DFSP) is a rare, slow?growing skin cancer that is primarily treated with surgery. Because this cancer can spread deep into the skin and surrounding tissue in an irregular way, it is notoriously difficult to ensure that it has been completely removed after conventional surgery and histological examination. Standard treatment in the UK is either wide local excision (WLE) or Mohs micrographic surgery (MMS).
doi : 10.1111/bjd.19838
Volume 184, Issue 4, April 2021, Pages: e127
Hidradenitis suppurativa is a chronic condition in which boil?like lumps develop in the armpits and groins, under the breasts and around the buttocks. There is often a delay in making a diagnosis, as it is often misdiagnosed as infection. The lesions are often painful and the condition greatly impairs quality of life.
doi : 10.1111/bjd.19839
Volume 184, Issue 4, April 2021, Pages: e128
Eczema is a common skin condition that affects around one in five children and one in ten adults. Qualitative research uses methods such as interviews to find out people’s views and experiences.
doi : 10.1111/bjd.19840
Volume 184, Issue 4, April 2021, Pages: e129
Mycosis fungoides is a type of blood cancer. The early phases of mycosis fungoides are represented by patches (flat lesions) or plaques (solid lesions) on the skin. Treatment usually consists of topical steroid creams, phototherapy (using ultraviolet light) or radiotherapy (using radiation). Together these methods are called skin?directed treatments. This study enrolled 395 patients with a new diagnosis of mycosis fungoides from 41 centres across 17 countries in Europe, North and South America, and Australia.
doi : 10.1111/bjd.19841
Volume 184, Issue 4, April 2021, Pages: e130
Skin cancer is the most common form of cancer in the UK. Cutaneous squamous cell cancer (cSCC) is a type of skin cancer that can spread to other parts of the body, which can reduce the patient’s chance of survival. There are over 44,500 cases of cSCC in the UK each year, so there is a need for research to help clinicians accurately identify patients with cSCC who are at high risk of their cancer spreading.
doi : 10.1111/bjd.19842
Volume 184, Issue 4, April 2021, Pages: e131
Basal cell carcinoma (BCC) is the most common form of skin cancer. There are several variants of BCC, called subtypes. The right treatment depends on several factors, including the specific subtype. To diagnose BCC and determine the subtype, usually a small skin sample (a ‘punch biopsy’) is taken under local anaesthesia. The results are available after about a week.
doi : 10.1111/bjd.19843
Volume 184, Issue 4, April 2021, Pages: e132
Recessive dystrophic epidermolysis bullosa (RDEB) is a rare disorder that leads to painful blisters and large open wounds of the skin that do not heal. Individuals with RDEB often develop skin tumours called cutaneous squamous cell carcinoma (cSCC), which are difficult to treat and rapidly get worse. The overall risk of death in patients with RDEB and cSCC can be up to 90% by the age of 55 years due to disease complications.
doi : 10.1111/bjd.19844
Volume 184, Issue 4, April 2021, Pages: e133
The human body is built up of millions of cells that together function as tissues and organs. Desmosomes are tiny structures on cell surfaces that enable cells not only to stick to their neighbours but also to communicate with them.
doi : 10.1111/bjd.19845
Volume 184, Issue 4, April 2021, Pages: e134
In humans there are more than 9000 diseases, many of which involve the skin. These problems arise because of faults (mutations) in the genetic code in human DNA. Finding these mutations helps dermatologists make accurate diagnoses.
doi : 10.1111/bjd.19846
Volume 184, Issue 4, April 2021, Pages: e135
Cutaneous melanoma (CM) is a type of skin cancer. The occurrence of CM in the Nordic countries has increased during the last 60 years. Studies of large populations can help us to understand how the proportion of people with a disease varies over time. However, few studies have examined the risk of CM in people of different occupations in this way. Our aim was to perform such a study in a large Nordic population.
doi : 10.1111/bjd.19847
Volume 184, Issue 4, April 2021, Pages: e136
Skin cancers are some of the commonest human cancers. Of the skin cancers, melanoma is the most serious diagnosis and has the highest chance of potentially being fatal. Early detection of melanoma has therefore been a goal of dermatologists and public health experts for many years. The development of smartphone applications (apps) that patients can use to survey or scan lesions (such as dark lumps or patches on their own skin) and that are enhanced by new technologies, such as artificial intelligence, and improve the chances of catching melanomas early to avoid poor outcomes would be a welcome addition.
doi : 10.1111/bjd.19848
Volume 184, Issue 4, April 2021, Pages: e137
????????? (DFSP) ???????????????, ???????????????????????????????????, ??????????????, ???????????????????????? (WLE) ??????? (MMS)?
doi : 10.1111/bjd.19849
Volume 184, Issue 4, April 2021, Pages: e138
?????????????, ????????????????????????????????, ????????????????, ???????????????????????????????????????????????????????????????, ?????????????, ????????????????? (PtGA) ?????????????????????????????????????
doi : 10.1111/bjd.19850
Volume 184, Issue 4, April 2021, Pages: e139
???????????, ????? 5 ?????? 1 ?, ? 10 ?????? 1 ?????????????, ?????????????????????????, ???????????????????????, ???????????????????????????????????, ????????????????????, ???????????????????????????????????????????
doi : 10.1111/bjd.19851
Volume 184, Issue 4, April 2021, Pages: e140
???????????????????? (?????) ??? (????) ???????????????????????????? (?????) ??? (?????) ??????????????????????????????????? 17 ???? 41 ?????? 395 ???????????????
doi : 10.1111/bjd.19852
Volume 184, Issue 4, April 2021, Pages: e141
?????????????????????? (cSCC) ??????, ??????????, ????????????????? 44,500 ? cSCC ??, ???????????????????????? cSCC ???
doi : 10.1111/bjd.19853
Volume 184, Issue 4, April 2021, Pages: e142
????? (BCC) ???????????BCC ?????, ?????????????????, ??????????? BCC ?????, ???????????????? (“????”) ????????????
doi : 10.1111/bjd.19854
Volume 184, Issue 4, April 2021, Pages: e143
??????????????? (RDEB) ???????, ???????????????????, ??????RDEB ??????????????? (cSCC) ?????, ?????????????????????, RDEB ? cSCC ?????????? 55 ?????? 90%?
doi : 10.1111/bjd.19855
Volume 184, Issue 4, April 2021, Pages: e144
???????????, ?????????????????????????????, ?????????????????, ???????????????????????????, ????????????????????????, ???????????????? (??) ?????????????, ?????????????????????????, ?????????, ????????
doi : 10.1111/bjd.19856
Volume 184, Issue 4, April 2021, Pages: e145
????, ? 9000 ????, ???????????????????? DNA ???????? (??) ???????????????????????
doi : 10.1111/bjd.19857
Volume 184, Issue 4, April 2021, Pages: e146
?????? (CM) ????????? 60 ???, ????? CM ????????????????????????????????????????, ??????????????????? CM ?????????????????????????
doi : 10.1111/bjd.19858
Volume 184, Issue 4, April 2021, Pages: e147
????????????????????, ??????????, ??????????????, ???????????????????????????????????????? (apps) ??????????? (??????????) , ??????????????????, ??????????????????????, ??????????????????
Do you want to add Medilib to your home screen?