JAMA Oncology




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Preexisting TP53-Variant Clonal Hematopoiesis and Risk of Secondary Myeloid Neoplasms in Patients With High-grade Ovarian Cancer Treated With Rucaparib

Tanya T. Kwan, PhD; Amit M. Oza, MD; Anna V. Tinker, MD; et al.

doi : 10.1001/jamaoncol.2021.4664

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Association Between Overall Survival and the Tendency for Cancer Programs to Administer Neoadjuvant Chemotherapy for Patients With Advanced Ovarian Cancer

Alexander Melamed, MD, MPH; J. Alejandro Rauh-Hain, MD, MPH; Allison A. Gockley, MD; et al.

doi : 10.1001/jamaoncol.2021.4252

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Fulvestrant-Palbociclib vs Letrozole-Palbociclib as Initial Therapy for Endocrine-Sensitive, Hormone Receptor–Positive, ERBB2-Negative Advanced Breast CancerA Randomized Clinical Trial

Antonio Llombart-Cussac, MD; José Manuel Pérez-García, MD; Meritxell Bellet, MD; et al.

doi : 10.1001/jamaoncol.2021.4301

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Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data SetAn International Agency for Research on Cancer TP53 Database Analysis

Christian P. Kratz, MD; Claire Freycon, MD; Kara N. Maxwell, MD, PhD; et al.

doi : 10.1001/jamaoncol.2021.4398

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Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes

Catherine Goudie, MD; Leora Witkowski, PhD; Noelle Cullinan, MD; et al.

doi : 10.1001/jamaoncol.2021.4536

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Clinical Activity and Safety of Cabozantinib for Brain Metastases in Patients With Renal Cell Carcinoma

Laure Hirsch, MD; Nieves Martinez Chanza, MD, PhD; Subrina Farah, MS; et al.

doi : 10.1001/jamaoncol.2021.4544

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Update of Incidence, Prevalence, Survival, and Initial Treatment in Patients With Non–Small Cell Lung Cancer in the US

Apar Kishor Ganti, MD; Alyssa B. Klein, MPH; Ion Cotarla, MD, PhD; et al.

doi : 10.1001/jamaoncol.2021.4932

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Cost-effectiveness Evaluation of the 2021 US Preventive Services Task Force Recommendation for Lung Cancer Screening

Iakovos Toumazis, PhD; Koen de Nijs, MSc; Pianpian Cao, MPH; et al.

doi : 10.1001/jamaoncol.2021.4942

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Uptake and Survival Outcomes Following Immune Checkpoint Inhibitor Therapy Among Trial-Ineligible Patients With Advanced Solid Cancers

Ravi B. Parikh, MD, MPP; Eun Jeong Min, PhD; E. Paul Wileyto, PhD; et al.

doi : 10.1001/jamaoncol.2021.4971

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Treatment Outcomes and Safety of Mobocertinib in Platinum-Pretreated Patients With EGFR Exon 20 Insertion–Positive Metastatic Non–Small Cell Lung CancerA Phase 1/2 Open-label Nonrandomized Clinical Trial

Caicun Zhou, PhD, MD; Suresh S. Ramalingam, MD; Tae Min Kim, MD, PhD; et al.

doi : 10.1001/jamaoncol.2021.4761

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Nodal Recurrence in Patients With Node-Positive Breast Cancer Treated With Sentinel Node Biopsy Alone After Neoadjuvant Chemotherapy—A Rare Event

Andrea V. Barrio, MD; Giacomo Montagna, MD, MPH; Anita Mamtani, MD; et al.

doi : 10.1001/jamaoncol.2021.4394

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Clinical Outcomes and Toxic Effects of Single-Agent Immune Checkpoint Inhibitors Among Patients Aged 80 Years or Older With CancerA Multicenter International Cohort Study

Caroline A. Nebhan, MD, PhD; Alessio Cortellini, MD; Weijie Ma, MD; et al.

doi : 10.1001/jamaoncol.2021.4960

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Occurrence of Pancytopenia Among Patients With Cancer Treated With Poly(Adenosine Diphosphate–Ribose) Polymerase InhibitorsA Pharmacoepidemiologic Study

Pierre-Marie Morice, PharmD, PhD; Basile Chrétien, PharmD, MSc; Angélique Da Silva, MD; et al.

doi : 10.1001/jamaoncol.2021.4672

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Association of Smoking Initiation and Cessation Across the Life Course and Cancer MortalityProspective Study of 410 000 US Adults

Blake Thomson, DPhil; Jonathan Emberson, PhD; Ben Lacey, MBChB, DPhil; et al.

doi : 10.1001/jamaoncol.2021.4949

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Compliance With Price Transparency Rules at US National Cancer Institute–Designated Cancer Centers

Fumiko Chino, MD; Jordan Johnson, BSRT, MSHA; Haley Moss, MD

doi : 10.1001/jamaoncol.2021.4979

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Interstitial Lung Disease Induced by Anti-ERBB2 Antibody-Drug ConjugatesA Review

Paolo Tarantino, MD; Shanu Modi, MD; Sara M. Tolaney, MD, MPH; et al.

doi : 10.1001/jamaoncol.2021.3595

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COVID-19 and CancerA Review of the Registry-Based Pandemic Response

Aakash Desai, MD, MPH; Turab J. Mohammed, MD; Narjust Duma, MD; et al.

doi : 10.1001/jamaoncol.2021.4083

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Painful Eruptions in a Patient With Cholangiocarcinoma Treated With Fibroblast Growth Factor Receptor Inhibitor

Natasha S. Wylie, DNP, APRN; Olayemi Sokumbi, MD; Jason S. Starr, DO

doi : 10.1001/jamaoncol.2021.5578

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Has the Current Oncology Value Paradigm Forgotten Patients’ Time?Too Little of a Good Thing

Adam Fundytus, MD; Vinay Prasad, MD, MPH; Christopher M. Booth, MD

doi : 10.1001/jamaoncol.2021.3600

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Adjuvant Chemotherapy for Stage I Pancreatic Ductal Adenocarcinoma—Is It Based on Evidence or Clinical Wisdom?

Lorenzo Gervaso, MD; Florian Lordick, MD, PhD; Nicola Fazio, MD, PhD

doi : 10.1001/jamaoncol.2021.3603

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A Coordinated Policy Approach to Address Medical Financial Toxicity

Cathy J. Bradley, PhD; K. Robin Yabroff, PhD; Ya-Chen Tina Shih, PhD

doi : 10.1001/jamaoncol.2021.3606

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Poly(ADP-Ribose) Polymerase Inhibitors and Myeloid Neoplasm Risk—Clues to a Mechanistic Connection?

Christine Walsh, MD, MS; Ilana Cass, MD

doi : 10.1001/jamaoncol.2021.4639

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The Long, Slow Road to Lung Cancer Cure

James L. Mulshine, MD; Bruce Pyenson, FSA, MAAA

doi : 10.1001/jamaoncol.2021.4711

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Immunotherapy Adverse Effects

Timothy J. Brown, MD; Ronac Mamtani, MD, MSCE; Erin M. Bange, MD

doi : 10.1001/jamaoncol.2021.5009

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