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Engineered Cell-Derived Vesicles Displaying Targeting Peptide and Functionalized with Nanocarriers for Therapeutic microRNA Delivery to Triple-Negative Breast Cancer in Mice (Adv. Healthcare Mater. 5/2022)

Rajendran JC Bose, Uday Sukumar Kumar, Fernando Garcia-Marques, Yitian Zeng, Frezghi Habte, Jason R McCarthy, Sharon Pitteri, Tarik F Massoud, Ramasamy Paulmurugan

doi : 10.1002/adhm.202270026

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Designer Extracellular Vesicles Modulate Pro-Neuronal Cell Responses and Improve Intracranial Retention (Adv. Healthcare Mater. 5/2022)

Lilibeth Ortega-Pineda, Alec Sunyecz, Ana I. Salazar-Puerta, Maria Angelica Rincon-Benavides, Diego Alzate-Correa, Amrita Lakshmi Anaparthi, Elizabeth Guilfoyle, Louisa Mezache, Heather L. Struckman, Silvia Duarte-Sanmiguel, Binbin Deng, David W. McComb, Daniel J. Dodd, William R. Lawrence, Jordan Moore, Jingjing Zhang, Eduardo Reátegui, Rengasayee Veeraraghavan, M. Tyler Nelson, Daniel Gallego-Perez, Natalia Higuita-Castro

doi : 10.1002/adhm.202270028

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Masthead: (Adv. Healthcare Mater. 5/2022)

doi : 10.1002/adhm.202270027

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Extracellular Vesicles — A Versatile Biomaterial

Juliane Nguyen, Gregor Fuhrmann

doi : 10.1002/adhm.202200192

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Extracellular Vesicles as an Emerging Treatment Option for Intervertebral Disc Degeneration: Therapeutic Potential, Translational Pathways, and Regulatory Considerations

Tyler J. DiStefano, Keti Vaso, George Danias, Henry N. Chionuma, Jennifer R. Weiser, James C. Iatridis

doi : 10.1002/adhm.202100596

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Liposomes and Extracellular Vesicles as Drug Delivery Systems: A Comparison of Composition, Pharmacokinetics, and Functionalization

Luke van der Koog, Timea B. Gandek, Anika Nagelkerke

doi : 10.1002/adhm.202100639

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Extracellular Vesicles as an Advanced Delivery Biomaterial for Precision Cancer Immunotherapy

Shaobo Ruan, Zachary Greenberg, Xiaoshu Pan, Pei Zhuang, Nina Erwin, Mei He

doi : 10.1002/adhm.202100650

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RNA and Protein Delivery by Cell-Secreted and Bioengineered Extracellular Vesicles

Bryan Z. Wang, Lori J. Luo, Gordana Vunjak-Novakovic

doi : 10.1002/adhm.202101557

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Engineered Cell-Derived Vesicles Displaying Targeting Peptide and Functionalized with Nanocarriers for Therapeutic microRNA Delivery to Triple-Negative Breast Cancer in Mice

Rajendran JC Bose, Uday Sukumar Kumar, Fernando Garcia-Marques, Yitian Zeng, Frezghi Habte, Jason R McCarthy, Sharon Pitteri, Tarik F Massoud, Ramasamy Paulmurugan

doi : 10.1002/adhm.202101387

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Designer Extracellular Vesicles Modulate Pro-Neuronal Cell Responses and Improve Intracranial Retention

Lilibeth Ortega-Pineda, Alec Sunyecz, Ana I. Salazar-Puerta, Maria Angelica Rincon-Benavides, Diego Alzate-Correa, Amrita Lakshmi Anaparthi, Elizabeth Guilfoyle, Louisa Mezache, Heather L. Struckman, Silvia Duarte-Sanmiguel, Binbin Deng, David W. McComb, Daniel J. Dodd, William R. Lawrence, Jordan Moore, Jingjing Zhang, Eduardo Reátegui, Rengasayee Veeraraghavan, M. Tyler Nelson, Daniel Gallego-Perez, Natalia Higuita-Castro

doi : 10.1002/adhm.202100805

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Extracellular Vesicles from 3D Engineered Microtissues Harbor Disease-Related Cargo Absent in EVs from 2D Cultures

Christopher Millan, Lukas Prause, Queralt Vallmajo-Martin, Natalie Hensky, Daniel Eberli

doi : 10.1002/adhm.202002067

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HOTAIR-Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing

Louis J. Born, Kai-Hua Chang, Pouria Shoureshi, Frank Lay, Sameer Bengali, Angela Ting Wei Hsu, Sanaz Nourmohammadi Abadchi, John W. Harmon, Steven M. Jay

doi : 10.1002/adhm.202002070

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Rapid Characterization and Quantification of Extracellular Vesicles by Fluorescence-Based Microfluidic Diffusion Sizing

Carolina Paganini, Britta Hettich, Marie R.G. Kopp, Adam Eördögh, Umberto Capasso Palmiero, Giorgia Adamo, Nicolas Touzet, Mauro Manno, Antonella Bongiovanni, Pablo Rivera-Fuentes, Jean-Christophe Leroux, Paolo Arosio

doi : 10.1002/adhm.202100021

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Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions

Britta Franziska Hettich, Johannes Josua Bader, Jean-Christophe Leroux

doi : 10.1002/adhm.202100047

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Injection-Free Delivery of MSC-Derived Extracellular Vesicles for Myocardial Infarction Therapeutics

Junnan Tang, Xiaolin Cui, Zenglei Zhang, Yanyan Xu, Jiacheng Guo, Bram G Soliman, Yongzheng Lu, Zhen Qin, Qiguang Wang, Hu Zhang, Khoon S Lim, Tim B F Woodfield, Jinying Zhang

doi : 10.1002/adhm.202100312

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Hydrogel Loaded with VEGF/TFEB-Engineered Extracellular Vesicles for Rescuing Critical Limb Ischemia by a Dual-Pathway Activation Strategy

Zheng Xing, Chen Zhao, Siwen Wu, Depeng Yang, Chunchen Zhang, Xinbo Wei, Xinran Wei, Haoran Su, Haifeng Liu, Yubo Fan

doi : 10.1002/adhm.202100334

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Enhancing the Stabilization Potential of Lyophilization for Extracellular Vesicles

Eduard Trenkenschuh, Maximilian Richter, Eilien Heinrich, Marcus Koch, Gregor Fuhrmann, Wolfgang Friess

doi : 10.1002/adhm.202100538

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Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase

Mina Mehanny, Tobias Kroniger, Marcus Koch, Jessica Hoppstädter, Dörte Becher, Alexandra K. Kiemer, Claus-Michael Lehr, Gregor Fuhrmann

doi : 10.1002/adhm.202101151

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An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability

Robert Richter, Mohamed A. M. Kamal, Marcus Koch, Bart-Jan Niebuur, Anna-Lena Huber, Adriely Goes, Carsten Volz, Julia Vergalli, Tobias Kraus, Rolf Müller, Nicole Schneider-Daum, Gregor Fuhrmann, Jean-Marie Pagès, Claus-Michael Lehr

doi : 10.1002/adhm.202101180

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Functional siRNA Delivery by Extracellular Vesicle–Liposome Hybrid Nanoparticles

Martijn J. W. Evers, Simonides I. van de Wakker, Ellis M. de Groot, Olivier G. de Jong, Jerney J. J. Gitz-François, Cor S. Seinen, Joost P. G. Sluijter, Raymond M. Schiffelers, Pieter Vader

doi : 10.1002/adhm.202101202

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In Situ Deployment of Engineered Extracellular Vesicles into the Tumor Niche via Myeloid-Derived Suppressor Cells

Silvia Duarte-Sanmiguel, Ana Panic, Daniel J. Dodd, Ana Salazar-Puerta, Jordan T. Moore, William R. Lawrence, Kylie Nairon, Carlie Francis, Natalie Zachariah, William McCoy, Rithvik Turaga, Aleksander Skardal, William E. Carson, Natalia Higuita-Castro, Daniel Gallego-Perez

doi : 10.1002/adhm.202101619

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Growth Media Conditions Influence the Secretion Route and Release Levels of Engineered Extracellular Vesicles

Jeremy P. Bost, Osama Saher, Daniel Hagey, Doste R. Mamand, Xiuming Liang, Wenyi Zheng, Giulia Corso, Oskar Gustafsson, André Görgens, CI Edvard Smith, Rula Zain, Samir El Andaloussi, Dhanu Gupta

doi : 10.1002/adhm.202101658

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