Inflammatory Bowel Diseases




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Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis

Jeffrey S Hyams, MD, Michael Brimacombe, PhD, Yael Haberman, MD, PhD, Thomas Walters, MD, Greg Gibson, PhD, Angela Mo, PhD, David Mack, MD, Anne Griffiths, MD, Brendan Boyle, MD, Neal LeLeiko, MD, PhD, James Markowitz, MD, Joel Rosh, MD, Ashish Patel, MD, Sapana Shah, MD, Robert Baldassano, MD, Marian Pfefferkorn, MD, Cary Sauer, MD, Joelynn Dailey, DO, Suresh Venkateswaran, PhD, Subra Kugathasan, MD, Lee A Denson, MD

doi : 10.1093/ibd/izab061

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Effect of ABT-263 on Intestinal Fibrosis in Human Myofibroblasts, Human Intestinal Organoids, and the Mouse Salmonella typhimurium Model

Laura A Johnson, BS, Eva S Rodansky, MS, Anhdao Tran, MS, Stephen G Collins, MS, Kathryn A Eaton, DVM, PhD, Benjamin Malamet, MS, Calen A Steiner, MD, Sha Huang, MS, Jason R Spence, PhD, Peter D R Higgins, MD, PhD, MS

doi : 10.1093/ibd/izab166

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Anti-TNF Therapy and the Risk of Herpes Zoster Among Patients With Inflammatory Bowel Disease

Christina Santella, MSc, Alain Bitton, MD, Christopher Filliter, MSc, Talat Bessissow, MD, MSc, Maria Vutcovici, MSc, Peter L Lakatos, MD, PhD, Paul Brassard, MD, MSc

doi : 10.1093/ibd/izab092

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Anti-Tumor Necrosis Factor-Alpha Withdrawal in Children With Inflammatory Bowel Disease in Endoscopic and Histologic Remission

Luca Scarallo, MD, Giulia Bolasco, MD, Jacopo Barp, MD, Martina Bianconi, MD, Monica di Paola, PhD, Michele Di Toma, MD, Sara Naldini, MD, Monica Paci, MD, Sara Renzo, MD, Flavio Labriola, MD, Salvatore De Masi, MD, Patrizia Alvisi, MD, Paolo Lionetti, MD, PhD

doi : 10.1093/ibd/izab046

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The Development and Initial Findings of A Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD)

Laura E Raffals, MD, MS, Sumona Saha, MD, MS, Meenakshi Bewtra, MD, Cecile Norris, MFA, Angela Dobes, MPH, Caren Heller, MD, MBA, Sirimon O’Charoen, PhD, Tara Fehlmann, MHS, Sara Sweeney, Alandra Weaver, MPH, Shrinivas Bishu, MD, Raymond Cross, MD, Themistocles Dassopoulos, MD, Monika Fischer, MD, MSc, Andres Yarur, MD, David Hudesman, MD, Deepak Parakkal, MD, Richard Duerr, MD, Freddy Caldera, MD, Joshua Korzenik, MD, Joel Pekow, MD, Katerina Wells, MD, Matthew Bohm, MD, Lilani Perera, MD, Manreet Kaur, MD, Matthew Ciorba, MD, Scott Snapper, MD, Elizabeth A Scoville, MD, Sushila Dalal, MD, Uni Wong, MD, James D Lewis, MD

doi : 10.1093/ibd/izab071

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Residual Short-Segment Distal Inflammation Has No Significant Impact on the Major Relapse of Extensive Ulcerative Colitis

Kunio Asonuma, MD, PhD, Taku Kobayashi, MD, PhD, Masaru Nakano, MD, PhD, Shintaro Sagami, MD, PhD, Hiroki Kiyohara, MD, PhD, Mao Matsubayashi, MD, Hiromu Morikubo, MD, Yusuke Miyatani, MD, Shinji Okabayashi, MD, Hajime Yamazaki, MD, PhD, Yuichiro Kuroki, MD, PhD, Toshifumi Hibi, MD, PhD

doi : 10.1093/ibd/izab062

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Collecting New Peak and Intermediate Infliximab Levels to Predict Remission in Inflammatory Bowel Diseases

Claire Liefferinckx, MD, PhD, Jérémie Bottieau, Jean-François Toubeau, PhD, Debby Thomas, PhD, Jean-François Rahier, MD, PhD, Edouard Louis, MD, PhD, Filip Baert, MD, PhD, Pieter Dewint, MD, Lieven Pouillon, MD, Guy Lambrecht, MD, François Vallée, PhD, Severine Vermeire, MD, PhD, Peter Bossuyt, MD, Denis Franchimont, MD, PhD Belgian Inflammatory Bowel Disease Research and Development Group

doi : 10.1093/ibd/izab042

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Vedolizumab Clinical Decision Support Tool Predicts Efficacy of Vedolizumab But Not Ustekinumab in Refractory Crohn’s Disease

Hadrien Alric, MD, Aurélien Amiot, MD, PhD, Julien Kirchgesner, MD, PhD, Xavier Tréton, MD, PhD, Mathieu Allez, MD, PhD, Yoram Bouhnik, MD, PhD, Laurent Beaugerie, MD, PhD, Franck Carbonnel, MD, PhD, Antoine Meyer, MD

doi : 10.1093/ibd/izab060

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Fecal Diversion for Perianal Crohn Disease in the Era of Biologic Therapies: A Multicenter Study

Jeffrey D McCurdy, MD, PhD, Jacqueline Reid, MD, Russell Yanofsky, MD, Vigigah Sinnathamby, Edgar Medawar, MD, Lara Williams, MD, Talat Bessissow, MD, Greg Rosenfeld, MD

doi : 10.1093/ibd/izab086

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Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Nonmelanoma Skin Cancer Rates From the Ulcerative Colitis Clinical Program

Bruce E Sands, MD, MS, Millie D Long, MPH, Walter Reinisch, MD, Julian Panés, MD, PhD, Edward V Loftus, Jr, MD, Chudy I Nduaka, DVM, PhD, Arif Soonasra, PharmD, Rajiv Mundayat, MSc, Nervin Lawendy, PharmD, Gary Chan, PharmD, MS, Gary S Friedman, MD, Chinyu Su, MD

doi : 10.1093/ibd/izab056

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Association of Circulating Fibrocytes With Fibrostenotic Small Bowel Crohn’s Disease

Aito Ueno, PhD, Humberto B Jijon, MD, PhD, Richard Peng, Steven Sparksman, MSc, Barbara Mainoli, BSc, Alexis Filyk, Yan Li, MSc, Stephanie Wilson, MD, Kerri Novak, MD, Remo Panaccione, MD, Simon Hirota, PhD, Antoine Dufour, PhD, Cathy Lu, MD, Paul L Beck, MD, PhD

doi : 10.1093/ibd/izab157

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Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis

Ahmed Al Saedi, PhD, Shilpa Sharma, MSc, Ebrahim Bani Hassan, PhD, Lulu Chen, PhD, Ali Ghasem-Zadeh, PhD, Majid Hassanzadeganroudsari, MSc, Jonathan H Gooi, PhD, Rhian Stavely, PhD, Rajaraman Eri, PhD, Dengshun Miao, MD, PhD, Kulmira Nurgali, PhD, Gustavo Duque, MD, PhD

doi : 10.1093/ibd/izab174

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Circular RNA HECTD1 Mitigates Ulcerative Colitis by Promoting Enterocyte Autophagy Via miR-182-5p/HuR Axis

Yan Xu, Yuxi Tian, PhD, Fujun Li, PhD, Ying Wang, MD, Junwen Yang, PhD, Hui Gong, MD, Xiaoping Wan, PhD, Miao Ouyang, PhD

doi : 10.1093/ibd/izab188

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Ileocolic Resection for Crohn Disease: The Influence of Different Surgical Techniques on Perioperative Outcomes, Recurrence Rates, and Endoscopic Surveillance

Benjamin Click, MD, MS, Amit Merchea, MD, Dorin T Colibaseanu, MD, Miguel Regueiro, MD, Francis A Farraye, MD, MSc, Luca Stocchi, MD

doi : 10.1093/ibd/izab081

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The Promise of Patient-Derived Colon Organoids to Model Ulcerative Colitis

Babajide A Ojo, PhD, Kelli L VanDussen, PhD, Michael J Rosen, MD, MSCI

doi : 10.1093/ibd/izab161

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Safety and Efficacy of Tofacitinib in Combination With Biologic Therapy for Refractory Crohn’s Disease

Scott David Lee, MD, Anand Singla, MD, Jason Harper, MD, Mitra Barahimi, MD, Jeffrey Jacobs, MD, Kendra J Kamp, RN, PhD, Kindra Dawn Clark-Snustad, DNP

doi : 10.1093/ibd/izab176

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New Gastrointestinal Symptoms Are Common in Inflammatory Bowel Disease Patients With COVID-19: Data From an International Registry

Ryan C Ungaro, MD, MS, Manasi Agrawal, MD, Erica J Brenner, MD, Xian Zhang, PhD, Jean-Frederic Colombel, MD, Michael D Kappelman, MD, MPH, Walter Reinisch, MD

doi : 10.1093/ibd/izab184

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Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice

David M Alvarado, PhD, Juhee Son, BS, Larissa B Thackray, PhD, Maria Florencia Gomez Castro, PhD, Sarada Prasad, BS, Xueyang Cui, MD, Naomi M Sonnek, MS, Michael S Diamond, MD, PhD, Siyuan Ding, PhD, Matthew A Ciorba, MD

doi : 10.1093/ibd/izab274

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Do Not Stop Anti-TNF Medications in Children With IBD When They Are Working

Jeremy Adler, MD, MSc, Grace J Lee, MD, Andrew A M Singer, MD

doi : 10.1093/ibd/izab047

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The Difficulty of Distal Crohn’s Disease and the Utility of Diverting Stomas

Nicole Elizabeth Kiefer Wieghard, MD, FACS, FASCRS

doi : 10.1093/ibd/izab146

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Fistula Healing Is Low After Fecal Diversion Surgery in Perianal Crohn’s Disease

Sheeva Johnson, MD, MPH, Jeffrey Ko, MD, Wissam J Halabi, MD, Jesse Stondell, MD, Maneesh Dave, MD, MPH

doi : 10.1093/ibd/izab210

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Simultaneous Development of Ulcerative Colitis in the Sigmoidocolon Autotransplant Neovagina and the Residual Colorectum

Yusuke Matsune, MD, Katsuki Yaguchi, MD, Shin Saito, MD, PhD, Hideya Sakakibara, MD, PhD, Yoshiaki Inayama, MD, PhD, Hideaki Kimura, MD, PhD, Reiko Kunisaki, MD, PhD

doi : 10.1093/ibd/izab222

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Potential Value of Electroacupuncture in the Treatment of Gastrointestinal Symptoms of COVID-19

Xianqiang Yu, PhD

doi : 10.1093/ibd/izab223

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Herpes Zoster in a Patient With Ulcerative Colitis After Vedolizumab Initiation—Causal Link or Only Temporal Coincidence?

Na Wu, MD, Hua Li, PhD, Jinyan Zhang, MD, Weifeng Huang, PhD

doi : 10.1093/ibd/izab229

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Tubercular Pleural Effusion in a Patient of Ulcerative Colitis Treated With Tofacitinib

Shubhra Mishra, MD, Anupam Kumar Singh, MD, Chirag Kopp, DM, Anuraag Jena, MD, Vishal Sharma, MD

doi : 10.1093/ibd/izab234

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Atypical Orofacial Granulomatosis Associated With Bowel Relapse in an Adult With Crohn’s Disease Under Anti-TNF Therapy

Parna Moghadam, MD, Marc Dumas, MD, Laurent Blum, MD, Isabel Gimenez, MD, Pascale Hervio, MD, Edouard Begon, MD

doi : 10.1093/ibd/izab235

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Association Between Inflammatory Bowel Disease and Atopic Dermatitis: A Two-Sample Mendelian Randomization Study

Xiaoyu Gu, BS, Xinchen Ke, BS, Minxue Shen, PhD, Mi Zhang, MD, Juan Su, MD

doi : 10.1093/ibd/izab240

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EQUIVALENT ADVERSE OUTCOMES FOR HOME AND HOSPITAL-BASED INFUSIONS OF INFLIXIMAB IN CHILDREN AND ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE

Shivani Gupta, Josh Bricker, Brendan Boyle, Ross Maltz, Hilary Michel, Jennifer Dotson

doi : 10.1093/ibd/izac015.000

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AHR EXPRESSION ON VIL1-EXPRESSING COLONIC EPITHELIAL CELLS IS ESSENTIAL FOR I3C-MEDIATED PROTECTION AGAINST COLITIS

Archana Saxena, Chandani Mitchell, Shanieka Stanley, Keisha Wilson, Alex Rutkovsky, P J Wisniewski, Nicholas Dopkins, Mitzi Nagarkatti, Prakash Nagarkatti, Philip Busbee

doi : 10.1093/ibd/izac015.001

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AUPHOS, A “FIRST-IN CLASS“ ORAL AGENT FOR CORRECTING METABOLIC DYSFUNCTION IN IBD

Lesley Wempe, Rana Mohamed, James Warinner, Tatiana Goretsky, Margarita Avdiushko, Jong Kim, Ahmed Abomhya, Goo Lee, Samuel Awuah, Terrence Barrett, Neeraj Kapur

doi : 10.1093/ibd/izac015.002

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AUPHOS, A NOVEL THERAPEUTIC THAT IMPROVES MITOCHONDRIAL FUNCTION AND AMELIORATES CHRONIC COLITIS

Rana Mohamed, James Warinner, Lesley Wempe, Margarita Avdiushko, Tatiana Goretsky, Jong Kim, Ahmed Abomhya, Goo Lee, Samuel Awuah, Terrence Barrett, Neeraj Kapur

doi : 10.1093/ibd/izac015.003

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CELL-AUTONOMOUS HEDGEHOG SIGNALING CONTROLS TH17 DIFFERENTIATION TO DRIVE INTESTINAL INFLAMMATION AND IS A DRUGGABLE TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE

Joachim Hanna, Flavio Beke, Louise O’Brien, Chrysa Kapeni, Hung-Chang Chen, Valentina Carbonaro, Alexander Kim, Timon E Adolph, Mikkel-Ole Skjoedt, Skjoedt Karsten, Marc de la Roche, Maike de la Roche

doi : 10.1093/ibd/izac015.004

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CELLULAR AND MOLECULAR IMPACT OF THE MELANOCORTIN RECEPTOR AGONIST PL8177 IN DEXTRAN SODIUM SULFATE (DSS)-INDUCED COLITIS IN RATS

Priyanka Dhingra, Alison Obr, Carl Spana, John Dodd, Paul Kayne

doi : 10.1093/ibd/izac015.005

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DIET AND ITS MICROENVIRONMENT INFLUENCE THE HEALTH OF COLON

Sunil Thomas, Giancarlo Mercogliano, George Prendergast

doi : 10.1093/ibd/izac015.006

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DISCOVERY OF IBD3540: A NOVEL GUT-RESTRICTED GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR WITH ORAL ACTIVITY IN MOUSE COLITIS MODELS

Diane Peters, Lauren Norris, Lukas Tenora, Ivan Snajdr, Xiaolei Zhu, Shinji Sakamoto, Ajit Thomas, Pavel Majer, Rana Rais, Barbara Slusher

doi : 10.1093/ibd/izac015.007

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GENERATION OF ANTIGEN-SPECIFIC REGULATORY T CELLS BYLACTOBACILLUS SPECIES

Alexa Weingarden, Djenet Bousbaine, Yiyin Chen, Michael Fischbach

doi : 10.1093/ibd/izac015.008

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LACTOCOCCUS LACTIS DELIVERY OF SURFACE LAYER PROTEIN A PROTECTS MICE FROM COLITIS BY RE-SETTING HOST IMMUNE REPERTOIRE

Bikash Sahay

doi : 10.1093/ibd/izac015.009

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MTADV 5-MER PEPTIDE SUPPRESSES IBD PATHOLOGY AND UNVEILS A NEW POTENTIAL TARGET-SERUM AMYLOID A

David Naor, Mary Cowman, Jin Kim, Maayan Hemed-Shaked

doi : 10.1093/ibd/izac015.010

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ORAL ADMINISTRATION OF NANOLIPOSOMES LOADED M13 MAY TREAT ULCERATIVE COLITIS AND COLITIS-ASSOCIATED CANCER WITHOUT CAUSING ANY SIDE EFFECTS

Dingpei Long, Chunhua Yang, Zahra Alghoul, Junsik Sung, Didier Merlin

doi : 10.1093/ibd/izac015.011

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TOFACITINIB TREATMENT PREVENTS POST-OPERATIVE RECURRENCE OF CROHN’S DISEASE MODELED BY ILEOCECAL RESECTION IN HLA-B27 TRANSGENIC RATS

Aurélie Blondeaux, Silvia Speca, Caroline Valibouze, Thomas Lambin, Caroline Dubuquoy, Marie Titecat, Helene Blanquart, Christel Neut, Michael Genin, Philippe Zerbib, Benoit Foligne, Pierre Desreumaux

doi : 10.1093/ibd/izac015.012

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ADVERSE CLINICAL OUTCOMES IN PATIENTS WITH CROHN’S DISEASE RECEIVING DIFFERENT SEQUENCES OF FIRST- AND SECOND-LINE BIOLOGIC TREATMENTS: FINDINGS FROM ROTARY

Noa Cleveland, Benjamin Chastek, Tito Ghosh, Ninfa Candela, Timothy Bancroft, Tao Fan, Kandavadivu Umashankar, David Rubin

doi : 10.1093/ibd/izac015.013

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ADVERSE CLINICAL OUTCOMES IN PATIENTS WITH ULCERATIVE COLITIS RECEIVING DIFFERENT SEQUENCES OF FIRST- AND SECOND-LINE BIOLOGIC TREATMENTS: FINDINGS FROM ROTARY

Noa Cleveland, Benjamin Chastek, Tito Ghosh, Ninfa Candela, Timothy Bancroft, Tao Fan, Kandavadivu Umashankar, David Rubin

doi : 10.1093/ibd/izac015.014

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DOSE ESCALATION OF BIOLOGIC THERAPIES IN BIOLOGIC TREATMENT-NA�VE ADULT PATIENTS WITH ULCERATIVE COLITIS: RESULTS FROM THE ODESSA DATABASE STUDY

Niranjan Kathe, Kandavadivu Umashankar, Kirti Mirchandani, Arunima Hait, Riyanka Paul, Tito Ghosh, Ninfa Candela, Tao Fan

doi : 10.1093/ibd/izac015.015

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EFFECTIVENESS OF ANTI-TNF THERAPY COMPARED TO IMMUNE MODULATOR FOR PREVENTION OF SURGICAL RECURRENCE IN PEDIATRIC CD

Matthew Egberg, Xian Zhang, Michael Phillips, Michael Kappelman

doi : 10.1093/ibd/izac015.016

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EFFICACY OF BIOLOGIC DRUGS IN SHORT-DURATION VERSUS LONG-DURATION INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND INDVIDUAL-PATIENT-DATA METANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Shomron Ben-Horin, Lena Novack, Ren Mao, Jing Guo, Yue Zhao, Ruslan Sergienko, Jian Zhang, Taku Kobayashi, Toshihumi Hibi, Yehuda Chowers, Laurent Peyrin-Biroulet, Jean-Frederic Colombel, Gilaad Kaplan, Min-Hu Chen

doi : 10.1093/ibd/izac015.017

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IDENTIFYING THE MOST EFFECTIVE TREATMENT ALGORITHM FOR THERAPIES TO TREAT MODERATE TO SEVERE ULCERATIVE COLITIS

Frank Scott, Anita Afzali, Parambir Dulai, Mei Lu, Ninfa Candela, Tao Fan, Tito Ghosh, James Lewis

doi : 10.1093/ibd/izac015.018

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SAFETY AND EFFECTIVENESS OF THE BNT162B2 MRNA COVID-19 VACCINE IN A NATIONWIDE COHORT OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Muhammad Khan, Kamran Mushtaq, Muhammad Saddique, Mohd Alghizzawi, Muhammad Yasir, Hafiz Younis, Farah Rashid, Deema AlSoub, Rafie Yakoob, Saad AlKaabi, Khalid Al-Ejji

doi : 10.1093/ibd/izac015.019

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ADDITIVE EFFECT OF PROBIOTICS ON 5-AMINOSALICYLIC ACID THERAPY IN PATIENT WITH ULCERATIVE COLITIS

Minjun Kim

doi : 10.1093/ibd/izac015.020

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CORTICOSTEROIDS AND 5ASA VERSUS CORTICOSTEROIDS ALONE FOR ACUTE SEVERE ULCERATIVE COLITIS: A RANDOMIZED CONTROLLED TRIAL

Shomron Ben-Horin, Ofir Har-Noy, Konstantinos Katsanos, Xavier Roblin, Min-Hu Chen, Xiang Gao, Doron Schwartz, Jae Hee Cheon, Monica Cesarini, Daniela Bojic, Marijana Protic, Angeliki Theodoropoulou, Heba Abu-Kaf, Tal Engel, Jian Tang, Pauline Veyrard, Xiaoqing Lin, Ren Mao, Dimitrios Christodoulou, Konstantinos Karmiris, Tamara Knezevic-Ivanovski

doi : 10.1093/ibd/izac015.021

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MIRIKIZUMAB IMPROVES PATIENT ASSESSMENT OF DISEASE SEVERITY AND CHANGE IN DISEASE ACTIVITY IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE

David Rubin, Paul Pollack, Theresa Hunter, Mingyang Shan, Lai-Shan Chan, Deanilee Deckard

doi : 10.1093/ibd/izac015.022

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MIRIKIZUMAB REDUCES ABDOMINAL PAIN IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE

Edward Loftus, Paul Pollack, Theresa Hunter, Mingyang Shan, Lai-Shan Chan, Deanilee Deckard, Raymond Cross

doi : 10.1093/ibd/izac015.023

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POPULATION PHARMACOKINETICS AND PHARMACODYNAMICS OF OZANIMOD IN ULCERATIVE COLITIS

Daniel Tatosian, Jun Shen, Lu Chen, Jean Lavigne, Nathan Teuscher, Sarah Harris, Denesh Chitkara, Giridhar Tirucherai, Cecilia Marta

doi : 10.1093/ibd/izac015.024

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POPULATION PHARMACOKINETICS OF OZANIMOD AND ACTIVE METABOLITE CC112273 IN PATIENTS WITH ULCERATIVE COLITIS

Jun Shen, Daniel Tatosian, Lamia Sid-Otmane, Nathan Teuscher, Lu Chen, Peijin Zhang, Giridhar Tirucherai, Denesh Chitkara, Cecilia Marta

doi : 10.1093/ibd/izac015.025

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SAFFRON AS AN ADJUVANT THERAPY IN ULCERATIVE COLITIS PATIENTS

Hassan Ashktorab, Philip Oppong-Twene, Holden Terry Maecker, Lakshmi Chirumamilla, Angesom Kibreab, Eiman Nabi, Adeyinka Laiyemo, Hassan Brim

doi : 10.1093/ibd/izac015.026

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INTERLEUKIN-17 RECEPTOR SIGNALING TO PANETH CELLS HELPS MAINTAIN INTESTINAL INTEGRITY AFTER GAMMA RADIATION INDUCED INJURY

Cody Kempen, Stephen Gaudino, Tej Bahadur, Ankita Singh, Pawan Kumar

doi : 10.1093/ibd/izac015.027

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THE USE OF IMMUNOSTAINING IN BIOPSIES TO EVALUATE EXPRESSION PATTERN AND PATHOPHYSIOLOGY ROLES OF ONCOSTATIN M AND ITS RECEPTOR BETA IN PEDIATRIC INFLAMMATORY BOWEL DISEASE

Jonathan Beri, Zhaoping He, Kudakwashe Chikwava, Zarela Molle-Rios

doi : 10.1093/ibd/izac015.028

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AUTOMATIC BLEEDING AND ULCER DETECTION FROM LIMITED QUALITY ANNOTATIONS IN ULCERATIVE COLITIS

Safaa Al-Ali, John Chaussard, Sébastien Li-Thiao-Té, Eric Ogier-Denis, Alice Percy-du-sert, Xavier Treton, Hatem Zaag

doi : 10.1093/ibd/izac015.029

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DEVELOPMENT AND VALIDATION OF A MACHINE LEARNING TOOL FOR EARLY DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE IN THE PRIMARY CARE SETTING: A POPULATION BASED STUDY

Tahel Ilan Ber, Amir Ben Tov, Sivan Gazit, Shlomit Steinberg-Koch, Benny Getz, Yonatan Jenudi, Dan Underberger, Or Ramni, Shomron Ben-Horin

doi : 10.1093/ibd/izac015.030

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REAL-TIME CONTINUOUS REPORTING OF IBD BIOMARKERS IN SWEAT

Badrinath Jagannath, Madhavi Pali, Kai-chun Lin, Devangsingh Sankhala, Abha Sardesai, Sriram Muthukumar, Shalini Prasad

doi : 10.1093/ibd/izac015.031

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RISK FACTORS FOR DEVELOPMENT OF PROSTATE CANCER IN PATIENT WITH INFLAMMATORY BOWEL DISEASE (IBD)

Ishaan Jakhar, Medha Singh, Suman Sahil, Annapoorna Singh, Daulath Singh

doi : 10.1093/ibd/izac015.032

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THE ASSESSMENT OF MRE FINDINGS ACCORDING TO CDAI SCORE IN PATIENTS WITH CROHN’S DISEASE

Monika Zbroja, Maryla Kuczynska, Weronika Cyranka, Malgorzata Nowakowska, Magdalena Grzegorczyk, Karolina Siejka, Monika Piekarska

doi : 10.1093/ibd/izac015.033

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UTILITY OF FIBROSCAN IN ULCERATIVE COLITIS?

Shubham Jain, Sujit Nair, Sanjay Chandnani, Parmeshwar Junare, Prasanta Debnath, Siddhesh Rane, Sameet Patel, Pravin Rathi

doi : 10.1093/ibd/izac015.034

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WHEN CROHN’S COMES TO RADIOLOGIST- THE ROLE OF MR ENTEROGRAPHY (MRE) IN THE DIAGNOSIS OF PENETRATING CROHN’S DISEASE IN PEDIATRIC AND ADULT PATIENTS

Weronika Cyranka, Maryla Kuczynska, Monika Zbroja, Malgorzata Nowakowska, Monika Piekarska, Karolina Siejka, Magdalena Grzegorczyk

doi : 10.1093/ibd/izac015.035

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AMINO ACID SENSING PATHWAYS IN INFLAMMATORY BOWEL DISEASE

Sumeet Solanki, Jun-Hee Lee, Yatrik Shah

doi : 10.1093/ibd/izac015.036

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DIET-ASSOCIATED INFLAMMATION, PHYSICAL ACTIVITY, AND HEALTH-RELATED OUTCOMES IN ULCERATIVE COLITIS

Kelli DuBois, Christine Blake, Caroline Rudisill, Sayward Harrison, James Hébert

doi : 10.1093/ibd/izac015.037

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EFFECTIVENESS OF CROHN’S DISEASE EXCLUSION DIET FOR INDUCTION OF REMISSION IN CROHN’S DISEASE ADULT PATIENTS

Martyna Szczubelek, Karolina Pomorska, Monika Korólczyk-Kowalczyk, Konrad Lewandowski, Magdalena Kaniewska, Grazyna Rydzewska

doi : 10.1093/ibd/izac015.038

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EFFICACY OF A DIGITALLY DELIVERED PERSONALIZED ELIMINATION DIET FOR THE SELF-MANAGEMENT OF INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME

Samuel Jactel, Joseph Olson, Jordan Brown, Kathleen Wolin, Valerie Jagiella

doi : 10.1093/ibd/izac015.039

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LONG TERM OUTCOMES OF PARTIAL ENTERAL NUTRITION THERAPY IN CHILDREN WITH CROHN’S DISEASE

Srisindu Vellanki, Anthony Borcich, Atu Agawu, Natalie Stoner, Albenberg Lindsey

doi : 10.1093/ibd/izac015.040

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MY SCD PROTOCOL - AN ONLINE, COMPREHENSIVE, REMOTELY-SUPERVISED PROTOCOL FOR IBD PATIENTS TO IMPLEMENT AN EFFECTIVE DIETARY INTERVENTION

Ali Arjomand, Rachelle Caviness

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NOVEL INSIGHTS INTO THE MECHANISM OF ACTION OF EXCLUSIVE ENTERAL NUTRITION IN CROHN’S DISEASE: PRE-CLINICAL STUDY IN A RODENT MODEL OF CROHN’S-LIKE COLITIS

Ramasatyaveni Geesala, You-Min Lin, Ke Zhang, Amosy M’Koma, Steven Cohn, Xuan-Zheng Shi

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SELECTIVELY IMPROVEMENT OF THE RESPONSE OF IMMUNE CELLS TO OPPORTUNISTIC MICROORGANISMS: AN INNOVATIVE PROPOSAL FOR IBD FROM AN ANCIENT GRAIN

Sergio Pumarola Segura

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SIMPLE SUGAR TRIGGERS SPONTANEOUS COLITIS DEVELOPMENT INIL10-/- MICE

Shahanshah Khan, Hasan Zaki

doi : 10.1093/ibd/izac015.044

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THE EFFECTS OF HIGH-FAT, LOW-FAT, AND SUCROSE-FREE DIETS ON MICE WITH INNATE IMMUNE MEDIATED COLITIS

Katelyn Ruley-Haase, Antonia Boger-May, Alvaro Torres Huerta, David Boone, Theodore Reed, Arpitha Mysore Rajashekara, Cameron Pederson, Ese-Onosen Omoijuanfo, Annie Cate Scmidt

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ACUITY OF PEDIATRIC INFLAMMATORY BOWEL DISEASE ADMISSIONS PRE AND DURING THE COVID-19 PANDEMIC

Malika Waschmann, Ariana Stuart, Henry Lin, Anna Hunter

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ADEQUACY OF SIGMOIDOSCOPY IN COMPARISION TO COLONOSCOPY TO ASSESS DISEASE ACTIVITY DURING FOLLOW UP IN PATIENTS WITH ULCERATIVE COLITIS

Sameet Patel, Shubham Jain, Sanjay Chandnani, Prasanta Debnath, Qais Contractor, Seemily Kahmei, Rima Kamat, Pravin Rathi

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CORRELATION OF FECAL, PLASMA, SERUM, AND SALIVARY CALPROTECTIN TO ENDOSCOPIC AND HISTOLOGIC OUTCOMES IN PATIENTS WITH CROHN’S DISEASE

Kendra Kamp, Kindra Clark-Snustad, Kamil Saad, Ernie Tolentino, Margaret Heitkemper, Neelendu Dey, Sean Gui, Scott D Lee

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CORRELATION OF PUCAI BETWEEN MAYO ENDOSCOPIC AND GEBOES PATHOLOGY SCORES IN ASSESSING DISEASE ACTIVITY OF PEDIATRIC PATIENTS WITH UC AMONG HISPANICS AND NON-HISPANICS

Francisco Durazo, Sonia Michail

doi : 10.1093/ibd/izac015.049

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INFLAMMATORY BOWEL DISEASE RISK STRATIFICATION AND MANAGEMENT IN A COMMUNITY PRACTICE SETTING

Angelina Collins, Sadie Swift, Adam Recht, Rose Prime, Robert Topp, Svetlana Beltyukova, Robert Goldklang, Franklin Gaylis

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POINT-OF-CARE INTESTINAL ULTRASOUND FOR THE DETECTION OF POSTOPERATIVE CROHN’S DISEASE ENDOSCOPIC RECURRENCE

Michael Dolinger, Zachary Stauber, Elizabeth Spencer, Maia Kayal, Nanci Pittman, Jean-Frederic Colombel, Marla Dubinsky

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TOWARDS A COMMON VALIDATED METHODOLOGY FOR HISTOLOGIC MEASUREMENT OF MUCOSAL HEALING IN ULCERATIVE COLITIS: INTRODUCING A NEW PROJECT OF THE BIOMARKERS CONSORTIUM OF THE FOUNDATION FOR THE NIH

Gerard Honig

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VALIDATION OF THE SIMPLIFIED ENDOSCOPIC MUCOSAL ASSESSMENT OF CROHN’S DISEASE (SEMA-CD) A NOVEL ENDPOINT TO ASSESS ENDOSCOPIC IMPROVEMENT WITH REAL WORLD DATA

Jeremy Adler, Richard Colletti, Lenore Noonan, Laurie Conklin, Kim Hung Lo, Yongling Xiao, Sheri Volger

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ANEMIA TREATMENT PATTERNS AND OUTCOMES AMONG A NATIONAL COHORT OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Carolyn Brooks, Shubhada Sansgiry, Jason Hou

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BURDEN OF ILLNESS OF OSTEOPOROTIC FRACTURES COMPARED TO OTHER SERIOUS DISEASES AMONG IBD PATIENTS

Raseen Tariq, Muhammad Waqas Tahir, Zoya Tahir, Faizan Zaheer, Abdul Wahab

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BURDEN OF NON-ALCOHOLIC FATTY LIVER DISEASE AMONG PATIENTS WITH CROHN’S DISEASE: ANALYSIS OF THE NATIONWIDE READMISSION DATABASE

Ahmed Abomhya, Mohammed Mahmoodurrahman, Daniel Mozell, Salman Ayaz, Hossam Hamad

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CHRONIC COLITIS IN MICE INDUCES KIDNEY INJURY: TRANSLATIONAL IMPLICATIONS FOR IBD

Gloria Ducasa, Hajar Hazime, Irina Fernandez, Nivis Brito, Ana Santander, Juan Burgueno, Maria Abreu

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COMPLICATIONS OF MYOCARDITIS IN INFLAMMATORY BOWEL DISEASE (IBD): A POPULATION-BASED COMPARATIVE STUDY BETWEEN ULCERATIVE COLITIS AND CROHN’S DISEASE

Neethi Dasu, Yaser Khalid, Brian Blair, Christopher Chhoun, Lucy Joo

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CROHN’S DISEASE AND ACUTE PANCREATITIS; ASSOCIATION, OUTCOMES, AND PREDICTORS OF 90-DAY READMISSION WITH ACUTE PANCREATITIS. INSIGHTS FROM THE NATIONWIDE READMISSION DATABASE

Ahmed Abomhya, Elizabeth Clemeston, Vijay Gayam, Farrah Khan, Denzil Etienne

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CURRENT VENOUS THROMBOEMBOLISM CHEMOPROPHYLAXIS PRACTICES AFTER SURGERY FOR IBD: SAVES-IBD TRIAL INITIAL REPORT

Stefan Holubar, Samuel Eisenstein, Liliana Bordeianou, Jeffrey Scow, Christopher Prien, Randolph Steinhagen, Alessandro Fichera, Tracy Hull

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ENDOSCOPIC STRICTUROTOMY – A NOVEL THERAPEUTIC MODALITY FOR IBD-RELATED STRICTURES: FIRST EUROPEAN EXPERIENCE

Martin Lukas, Martin Kolar, Martin Vasatko, Milan Lukas

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MICROSCOPIC COLITIS IS ASSOCIATED WITH DECREASED BONE DENSITY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Natapat Chaisidhivej, Aunchalee Jaroenlapnopparat, Ben Ponvilawan, Nessa Tantivit, Michael E Goldberg

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NON-IMMUNE MEDIATED MUSCULOSKELETAL DISEASE IN CROHN’S DISEASE PATIENTS BEING EVALUATED FOR INFLAMMATORY SPONDYLOARTHRITIS - A PILOT STUDY

Monica Schwartzman, Randy Longman, Ellen Scherl, Sergio Schwartzman

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NON-IMMUNE MEDIATED MUSCULOSKELETAL DISEASE IN INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW OF THE LITERATURE

Monica Schwartzman, Sergio Schwartzman

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PAIN IN INFLAMMATORY BOWEL DISEASE (IBD): DOES OPIOID USE PREDICT WORSE HOSPITAL OUTCOMES?

Neethi Dasu, Yaser Khalid, Brian Blair, C Jonathan Foster

doi : 10.1093/ibd/izac015.065

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THE IMPACT OF CARDIAC ARRHYTHMIAS ON INFLAMMATORY BOWEL DISEASE (IBD)

Neethi Dasu, Yaser Khalid, Brian Blair, Justin Derosa, Drew Chiesa

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THE OPIOID EPIDEMIC: ASSESSING OUTCOMES OF OPIOID ABUSE IN CHRONIC INFLAMMATORY DISEASE (ULCERATIVE COLITIS VS CROHN’S DISEASE)

Neethi Dasu, Yaser Khalid, Brian Blair, Justin Derosa, Donald McMahon

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COST-EFFECTIVENESS OF TOFACITINIB FOR THE TREATMENT OF MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS IN COLOMBIA

Fabio Gil, Fabian Julian-Banos, Luisa Amador, Natalia Castano, Juan Reyes

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GEOGRAPHIC DIFFERENCES IN THE RISK OF SURGERY IN INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS

Tawnya Hansen, Joyce Mak, Fox Underwood, Joseph Windsor, James King, Joshua Quan, Michael Buie, Stephanie Coward, Alex Frolkis, Alexander Leung, Christopher Ma, Kerri Novak, Remo Panaccione, Yiming Qian, Johan Burisch, Richard Gearry, Siew Ng, Gilaad Kaplan

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GLOBAL HOSPITALIZATION TRENDS FOR CROHN’S DISEASE AND ULCERATIVE COLITIS: SYSTEMATIC REVIEW WITH TEMPORAL ANALYSES

Michael Buie, Joshua Quan, Joseph Windsor, Stephanie Coward, Richard Gearry, Tawnya Hansen, James King, Paulo Kotze, Siew Ng, Joyce Mak, Remo Panaccione, Cynthia Seow, Fox Underwood, Gilaad Kaplan

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IMPACT OF CURRENT AND FORMER SMOKING ON THE RISK OF ULCERATIVE COLITIS AMONG FAMILY HISTORY POSITIVE AND NEGATIVE INDIVIDUALS; EVIDENCE FOR GENE-SMOKING INTERACTION FROM LARGE SCALE POPULATION-BASED COHORT STUDY IN KOREA

Hyeong Sik Ahn, Hyun Jung Kim

doi : 10.1093/ibd/izac015.071

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INCIDENCE AND PREVALENCE OF PRIMARY SCLEROSING CHOLANGITIS: A META-ANALYSIS OF POPULATION-BASED STUDIES

Jared Cooper, Ante Markovinovic, Stephanie Coward, Aziz Shaheen, Mark Swain, Remo Panaccione, Christopher Ma, Kerri Novak, Gilaad Kaplan

doi : 10.1093/ibd/izac015.072

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PREDICTORS OF CLINICAL RELAPSE AMONG PATIENTS WITH ULCERATIVE COLITIS IN ENDO-HISTOLOGIC REMISSION

Tanya Zeina, Shiv Gandhi, Akaash Mittal, Alexander Levy, Joel Weinstock, Sushrut Jangi

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SEROLOGICAL RESPONSES TO SARS-COV-2 VACCINATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY

Joshua Quan, Christopher Ma, Remo Panaccione, Jamil Kanji, Graham Tipples, Nastaran Sharifi, Michelle van Huyssteen, Ante Markovinovic, LeeAnn Turnbull, Gurmeet Bindra, Douglas Mahoney, Richard Ingram, Lindsay Hracs, Stephanie Coward, Joseph Windsor, Michael Buie, Melissa Chan, Jose Ferraz, Cathy Lu, Meena Mathivanan, Kerri Novak, Cynthia Seow, Tushar Shukla, Gilaad Kaplan

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DECREASED EXPRESSION OF NHE3 IN COLON CANCER EPITHELIUM IS ASSOCIATED WITH DNA DAMAGE, INCREASED LOCAL INFLAMMATION AND TUMOR GROWTH

Daniel Laubitz, Michael Gurney, Monica Midura-Kiela, Christy Clutter, Hao Chen, Fayez Ghishan, Pawel Kiela

doi : 10.1093/ibd/izac015.075

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EPITHELIAL DUOX2 ACTIVATION INCREASES GUT PERMEABILITY AND BACTERIAL TRANSLOCATION THAT IS RESCUED WITH BUTYRATE SUPPLEMENTATION

Hajar Hazime, Gloria Ducasa, Irina Fernandez, Nivis Brito, Ana Santander, Judith Pignac-Kobinger, Gregory Conner, Juan Burgueno, Maria Abreu

doi : 10.1093/ibd/izac015.076

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ILEAL ENTEROCYTE BRUSH BORDER ABNORMALITIES ASSOCIATE WITH PROGRESSIVE DISEASE COURSE IN PEDIATRICS CROHN’S DISEASE

Yael Haberman, Jefferson Vallance, Julie Baverman, Ta-Chiang Liu, Subra Kugathasan, Lee Denson, Kelli Van Dussen

doi : 10.1093/ibd/izac015.077

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MATRIX METALLOPROTEINASE (MMP-9) INDUCED INCREASE IN INTESTINAL EPITHELIAL TIGHT JUNCTION BARRIER IS MEDIATED BY EGFR ACTIVATION

Rana Al-Sadi, Jessica Engers, Mohammad Haque

doi : 10.1093/ibd/izac015.078

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METHYLTRANSFERASE SMYD2 MODULATES THERAPEUTIC EFFECTS OF EPIDERMAL GROWTH FACTOR IN INFLAMMATORY BOWEL DISEASE

Xiaoqing Guan, Yuning Hou, Shaligram Sharma, Chunying Li

doi : 10.1093/ibd/izac015.079

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NEW OXPHOS REGULATING COMPOUND – AUPHOS – INCREASES MITOCHONDRIAL COMPLEXES EXPRESSION IN MURINE AND HUMAN INTESTINAL EPITHELIAL CELLS

Ahmed Elsayed, Ahmed Abomhya, Margarita Avdiushko, Neeraj Kapur, Samuel Awuah, Terrence Barrett, Tatiana Goretsky

doi : 10.1093/ibd/izac015.080

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NOVEL CONTRIBUTIONS OF CLAUDIN-4 TO EPITHELIAL BARRIER REGULATION AND COLITIS

Nitesh Shashikanth, Yunuo Liu, Tiaosi Xing, Jerrold Turner

doi : 10.1093/ibd/izac015.081

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OXPHOS DRIVES CRYPT FISSIONING REQUIRED FOR HEALING OF IBD ULCERS

Ahmed Abomhya, Tatiana Goretsky, Neeraj Kapur, Courtney Perry, Margarita Avdiushko, Emily Bradford, Terrence Barrett

doi : 10.1093/ibd/izac015.082

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PLIN2 IS AN ARYL HYDROCARBON RECEPTOR TRANSCRIPTIONAL TARGET AND MAY CONTRIBUTE TO MUCOSAL RESTITUTION

Deanna Davis, Matthew Ciorba, David Alvarado

doi : 10.1093/ibd/izac015.083

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PPI ADMINISTRATION CAUSES COLONIC TIGHT JUNCTION BARRIER DYSFUNCTION VIA INCREASE INENETROCOCCUS FECALIS

Meghali Nighot, Nathan Morris, Prashant Nighot, Kofi Clarke, Thomas Ma

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GENETIC OVERLAP BETWEEN INFLAMMATORY BOWEL DISEASE AND PARKINSON’S DISEASE IMPLICATES THE ROLE OF ADAPTIVE IMMUNE RESPONSE IN THEIR COMORBIDITY

Thomas Otten, Jonathan Ayash, Wonjun Lee, Haoxiang Cheng, Anketse Debebe, Ke Hao, Lauren Peters, Johan Björkegren, Olivia Kalash, Mellissa Picker, Alexa Rendon, Jean-Frederic Colombel, Rachel Saunders-Pullman, Marcus Unger, Inga Peter

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A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT

Courtney Crane, Justin Bowser, Rachael Fasnacht, Jennifer Gardell, Meghan Maurer, Susan Julien, Megan Templeton, Jon Henry Therriault, Kristine Swiderek

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ADHERENT-INVASIVEE. COLI PROMOTE ER STRESS TO SUPPORT IL23R-DRIVEN AGR2-DEPENDENT ILEOCOLITIS

Monica Viladomiu, Manirath Khounlotham, Belgin Dogan, Svetlana Lima, Ahmed Elsaadi, Jeremy Herzog, Alexi Schoenborn, Melissa Ellermann, Bo Liu, Shiying Zhang, Ajay Gulati, R Balfour Sartor, Kenneth Simpson, Steve Lipkin, Randy Longman

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ALTERED MICROBIAL BIOGEOGRAPHY IN INNATE IMMUNE-MEDIATED COLITIS

Antonia Boger-May, Diana La La Torre, Katelyn Ruley-Haase, Lauren English, Connor Roncagli, Theodore Reed, Hunter Hoffman, Anne-Marie Overstreet, David Boone

doi : 10.1093/ibd/izac015.088

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CHRONIC COLITIS ALTERS BRAIN ACTIVITY BY INDUCING HMGB1-MEDIATED PYROPTOSIS IN MICE

Jonathon Mitchell, Su Jin Kim, Cody Howe, Marisa Patel, Gayoung Kim, Gwangbeom Heo, Eunok Im, Sang Rhee

doi : 10.1093/ibd/izac015.089

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GENERATION OF HUMAN INTESTINAL ORGANOIDS CONTAINING TISSUE-RESIDENT IMMUNE CELLS

Kentaro Tominaga, Dan Kechele, Guillermo Sanchez, Heather McCauley, Jacob Enriquez, Simon Vales, Ingrid Jurickova, Lee Denson, Takanori Takebe, Michael Helmrath, Aaron Zorn, James Wells

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INTERLEUKIN 21-INDUCED METABOLIC REPROGRAMMING DRIVES CD4 T CELL INFLAMMATORY RESPONSE DURING INTESTINAL INFLAMMATION

Adebowale Bamidele, Mary Sagstetter, Petra Hirsova, Guilherme Piovezani Ramos, Emily Klatt, Maria Westphal, William Faubion

doi : 10.1093/ibd/izac015.091

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MASS CYTOMETRY ANALYSIS OF CROHN’S DISEASE-LIKE PHENOTYPE OF THE ILEOANAL POUCH FOLLOWING ILEAL POUCH-ANAL ANASTOMOSIS FOR ULCERATIVE COLITIS

Siyan Cao, Marina Cella, Natalia Jaeger, Matthew Ciorba, Guadalupe Oliva Escudero, Alexandra Gutierrez, Richard Rood, Deborah Rubin, Parakkal Deepak, Marco Colonna

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NOD2 PROMOTES HOST DEFENSE AND RECOVERY INDUCING MACROPHAGE-MEDIATED INNATE LYMPHOID CELLS TYPE 3 ACTIVATION FOLLOWING FUNGAL INFECTION IN EXPERIMENTAL COLITIS

Morgan McAndrew, Hannah Havran, Luca Di Martino, Mahmoud Ghannoum, Theresa Pizarro, Carlo De Salvo

doi : 10.1093/ibd/izac015.093

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NOVEL FUNCTION OF MYELOID METHYLTRANSFERASE SMYD5 IN INFLAMMATORY BOWEL DISEASE PROGRESSION

Yuning Hou, Xiaoqing Guan, Shaligram Sharma, Chunying Li

doi : 10.1093/ibd/izac015.094

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THE ROLE OF GROUP 3 INNATE LYMPHOID CELLS (ILC3) IN GM-CSF/CSF2RB-DEPENDENT INTESTINAL HOMEOSTASIS IN CROHN’S DISEASE

Ling-shiang Chuang, Joshua Morrison, Zhi Chai, Ujunwa Korie, Arthur Mortha, Sacha Gnjatic, Judy Cho

doi : 10.1093/ibd/izac015.095

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TNFAIP3 DRIVES COLITIS THROUGH DEATH CELL AND TNFα PRODUCTION

Alvaro Torres Huerta, Katelyn Ruley-Haase, Antonia Boger-May, David Boone

doi : 10.1093/ibd/izac015.096

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A NOVEL MICROBIALLY-DERIVED PROTEIN CAN BE EXPRESSED INLACTOCOCCUS LACTIS AND DELIVERED ORALLY TO IMPROVE GUT BARRIER FUNCTION AND PREVENT FIBROGENESIS BY INTERACTING WITH THE EXTRACELLULAR MATRIX DURING GI INJURY

Chip La La Chat, Eskedar Nigatu, Elisabeth Messner, Bernat Baeza Raja, Jill Desnoyer, Amy Jo Johnson, Michi Willcoxon, Stefanie Banas, Andrew Han, Todd DeSantis, Karim Dabbagh, Irina Shilova, Lynn Yamamoto

doi : 10.1093/ibd/izac015.097

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A NOVEL ORALLY ACTIVE METABOLITE REVERSES CROHN’S DISEASE-ASSOCIATED INTESTINAL FIBROSIS

Hon Wai Koon

doi : 10.1093/ibd/izac015.098

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ACTIVATION OF MK2 IN CROHN’S DISEASE-ASSOCIATED FIBROSIS: NEW TARGET FOR ANTI-FIBROTIC THERAPY

Marina Chulkina, Steven McAninch, Melanie Ehudin, Claire Cohen, Sinisa Dovat, Walter Koltun, Gregory Yochum, Irina Pinchuk, Ellen Beswick

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EICOSATETRAYNOIC ACID REGULATES MITOCHONDRIAL AND EXTRA-CELLULAR MATRIX GENE EXPRESSION AND TISSUE STIFFNESS IN A HUMAN INTESTINAL ORGANOID MODEL OF ILEAL CROHN’S DISEASE

Ingrid Jurickova, Alex Huron, Elizabeth Angerman, Erin Bonkowski, Anil Jegga, Yael Haberman, Lee Denson

doi : 10.1093/ibd/izac015.100

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GPX3 IS REQUIRED TO MEDIATE PROTECTIVE EFFECTS OF GPX1 LOSS IN COLITIS

Koral Blunt, Justin Jacobse, Margaret Allaman, Mary Washington, Jeremy Goettel, Keith Wilson, Christopher Williams, Sarah Short

doi : 10.1093/ibd/izac015.101

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INCREASE IN MK2 ACTIVITY IN CROHN’S DISEASE: ROLE IN THE INFLAMMATORY ACTIVATION OF FIBROBLASTS

Marina Chulkina, Steven McAninch, Melanie Ehudin, Sinisa Dovat, Walter Koltun, Gregory Yochum, John Valentine, Ellen Beswick, Irina Pinchuk

doi : 10.1093/ibd/izac015.102

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NIPEP-IBD; A SYNTHETIC PEPTIDE TARGETING NOVEL MOLECULE, INTEGRIN BETA 1, TO RESTITUTE INTESTINAL EPITHELIAL CELLS FOR INFLAMMATORY BOWEL DISEASE (IBD) TREATMENT

Deogil Kim, Dong Woo Lee, Eui Kyun Jeong, Hoo Cheol Lee, Yoon Shin Park, Jue Yeon Lee, Chong Pyung Chung, Yoon Jeong Park

doi : 10.1093/ibd/izac015.103

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TH17 CELLS PROMOTE INTESTINAL FIBROSIS THROUGH THE PRODUCTION OF AMPHIREGULIN

Wenjing Yang, Tianming Yu, Suxia Yao, Irina Pinchuk, Yingzi Cong

doi : 10.1093/ibd/izac015.104

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LACTOBACILLUS MURINUS ACTIVATES THE ARYL HYDROCARBON RECEPTOR TO ATTENUATE TNF-ALPHA-INDUCED PRO-INFLAMMATORY RESPONSES IN HUMAN INTESTINAL EPITHELIAL CELLS

Husnain Ahmed, Julia Bell, Linda Mansfield

doi : 10.1093/ibd/izac015.105

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RANDOMIZED, DOUBLE-BLIND, PLACEBO (PBO)-CONTROLLED, SINGLE- AND MULTIPLE-DOSE PHASE 1 STUDY OF VE202, A DEFINED BACTERIAL CONSORTIUM FOR TREATMENT OF IBD: SAFETY AND COLONIZATION DYNAMICS OF A NOVEL LIVE BIOTHERAPEUTIC PRODUCT (LBP) IN HEALTHY ADULTS

Jeffrey Silber, Jason Norman, Tokuwa Kanno, Emily Crossette, Rose Szabady, Rajita Menon, Melissa Marko, Bernat Olle, Esi Lamousé-Smith

doi : 10.1093/ibd/izac015.106

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SELECTION OF MICROBIOME-DERIVED PEPTIDES THROUGH MULTI-TECHNOLOGY META-ANALYSIS, BINDING, AND FUNCTIONAL ASSAYS, IDENTIFIES PEPTIDES WITH THERAPEUTIC POTENTIAL THAT MODULATE IMMUNE RESPONSES AND DISEASE

Michelle Lin, Eun Ok Kim, Jill Desnoyer, Nicole Narayan, Jayamary Ravichandar, Sabina Lau, Bum-Yeol Hwang, Amy Jo Johnson, Michi Willcoxon, Todd DeSantis, Karim Dabbagh, Lynn Yamamoto

doi : 10.1093/ibd/izac015.107

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BRAIN FOG IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE, AND ASSOCIATION WITH USE OF PROBIOTICS

Apaar Dadlani, Khushboo Gala, Jayesh Rai, Shesh Rai, Gerald Dryden

doi : 10.1093/ibd/izac015.108

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COMPARING THE GUT METABOLOMIC PROFILES IN HISPANIC AND NON-HISPANIC PEDIATRIC ULCERATIVE COLITIS PATIENTS

Parastou Khalessi Hosseini, Sonia Michail

doi : 10.1093/ibd/izac015.109

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FECAL MICROBIOTA OF PEOPLE WITH CROHN’S DISEASE DOES NOT CHANGE WITH ILEOCECAL RESECTION

Daphne Moutsoglou, Alexander Khoruts, Byron Vaughn

doi : 10.1093/ibd/izac015.110

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INTESTINAL EPITHELIAL CELL-SPECIFIC CFTR KNOCKOUT MICE EXHIBIT FECAL MICROBIAL DYSBIOSIS

Sarah Young, Aaron Ericsson, Rowena Woode, Lane Clarke

doi : 10.1093/ibd/izac015.111

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KLEBSIELLA PNEUMONIAE IN THE COLONIC MUCUS LAYER INFLUENCESCLOSTRIDIODES DIFFICILE PATHOGENESIS

Taylor Ticer, Rachel Stine, Amy Engevik, Melinda Engevik

doi : 10.1093/ibd/izac015.112

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THE MICROBIAL LANDSCAPE OF ULCERATIVE COLITIS IN ENDOSCOPIC REMISSION

Sushrut Jangi, Glenn Robison, Paola Sebastiani, Jimmy Crott, Joel Weinstock, Siddharth Singh, Dominique Michaud

doi : 10.1093/ibd/izac015.113

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THE SYNTHETIC GLYCAN KB295 OPTIMIZES MICROBIOME COMPOSITION AND FUNCTION IN ULCERATIVE COLITIS – RESULTS FROM A PROOF OF PRINCIPLE HUMAN STUDY

Jeffrey Meisner, Toni Bransford, Kelsey Miller, Jackson Lee, Adarsh Jose, Michael Giuggio, Megan McComb, Eric Humphries, Madeline Rosini, Mark Wingertzahn, Fergus Shanahan, Johan E T van Hylckama Vlieg, Mark Dowling

doi : 10.1093/ibd/izac015.114

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TRENDS IN ADMISSIONS, OUTCOMES AND FINANCIAL BURDEN OFC. DIFFICILE INFECTION RELATED HOSPITALIZATIONS AMONG INFLAMMATORY BOWEL DISEASE PATIENTS: A NATIONWIDE ANALYSIS

Muhammad Waqas Tahir, Raseen Tariq, Zoya Tahir, Arsalan Zaheer, Sahil Khanna

doi : 10.1093/ibd/izac015.115

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CLINICAL FEATURES AND OUTCOMES OF PAEDIATRIC PATIENTS WITH ISOLATED COLONIC CROHN’S DISEASE: A MULTICENTRE STUDY FROM THE PAEDIATRIC IBD PORTO GROUP OF ESPGHAN

Tal Berger, HPaolo Lionetti, Luca Scarallo, Marco Gasparetto, Nicholas M Croft, Erasmo Miele, Annamaria Staiano, Joseph Meredith, Marina Aloi, Patrizia Alvisi, Darja Urlep, Batia Weiss, Mikkel Malham, Manar Matar, Víctor Navas-López, Claudio Romano, Valeria Dipasquale, Lorenzo Norsa, Kaija-Leena Kolho, Raanan Shamir, Dror Shouval uey Miin Lee, Lavenya Ramasamy Padmanaban, Eytan Wine, Anat Yerushalmy-Feler, Iva Hojsak, Denis Kazeka, Daniela Elena Serban, Dotan Yogev, Oren Ledder,

doi : 10.1093/ibd/izac015.116

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COMPARISON OF THE INFLAMMATORY BOWEL DISEASES PHENOTYPE AND COURSE IN THE ELDERLY- AND EARLY-ONSET PATIENTS

Bahar Saberzadeh-Ardestani, Amir Anushiravani, Bardia Khosravi, Homayoon Vahedi, Masoud Malekzadeh, Sudabeh Alatab, Anahita Sadeghi, Ali Reza Sima, Reza Malekzadeh

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DEVELOPMENT AND VALIDATION OF THE CROHN’S DISEASE-HEALTH INDEX (CD-HI), A CLINICALLY-RELEVANT, DISEASE-SPECIFIC PATIENT-REPORTED OUTCOME MEASURE

Jamison Seabury, Jennifer Weinstein, Spencer Rosero, Anika Varma, Ellen Wagner, Christine Zizzi, Nuran Dilek, Michael McDermott, Aaron Kaat, Lawrence Saubermann, Larissa Temple, Scott Rogoff, Chad Heatwole, Zach Rose

doi : 10.1093/ibd/izac015.118

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IMPACT OF TIMING OF INITIATION OF INFLIXIMAB ON THE RISK OF IBD-RELATED SURGERY AND COMPLICATIONS

Denise Young, Aravind Thavamani, Jaime Perez, Jonathan Moses

doi : 10.1093/ibd/izac015.119

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INCIDENTALLY DIAGNOSED ASYMPTOMATIC CROHN’S DISEASE: LONG-TERM CLINICAL OUTCOMES OF UNTREATED PATIENTS

Ana Grinman, Bella Ungar, Adi Lahat, Uri Kopylov, Rami Eliakim, Shomron Ben-Horin

doi : 10.1093/ibd/izac015.120

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INFLAMMATORY BOWEL DISEASE IN APPALACHIA: AN INVESTIGATION INTO DISPARATE OUTCOMES WITHIN THE STATE OF KENTUCKY

Courtney Perry, Christian Rhudy, Deborah Flomenhoft, Jeffrey Talbert, Terrence Barrett

doi : 10.1093/ibd/izac015.121

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LONG TERM ADVERSE HEALTH OUTCOMES IN OFFSPRING FROM MOTHERS WITH INFLAMMATORY BOWEL DISEASE: A NATIONWIDE POPULATION BASED STUDY IN KOREA

Hyeong Sik Ahn, Hyun Jung Kim

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OUTCOMES OF TOTAL PROCTOCOLECTOMY (TPC) WITH ILEAL POUCH ANAL ANASTOMOSIS (IPAA)

Jessica Petrov, Badr Al-Bawardy, Jill Gaidos, Deborah Proctor

doi : 10.1093/ibd/izac015.123

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PREDICTORS AND OUTCOMES OF BIOLOGIC/IMMUNOSUPPRESSIVE THERAPY FOR PSC-ASSOCIATED IBD

Amr Sayed, Marina Silveira, David Assis, Yanhong Deng, Jill Gaidos, Deborah Proctor, Badr Al-Bawardy

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RELATIONSHIP BETWEEN SELF-REPORTED SLEEP AND DISEASE ACTIVITY DIFFERS BASED ON ENDOSCOPIC OR CLINICAL DISEASE ACTIVITY MEASURES

Kendra Kamp, Kindra Clark-Snustad, Linda Yoo, Diana Buchanan, Jeffrey Jacobs, Mitra Barahimi, Margaret Heitkemper, Scott D Lee

doi : 10.1093/ibd/izac015.125

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UHPLC-MS/MS-BASED PLASMA LIPIDOMICS REVEAL ALTERATIONS ASSOCIATED WITH EXCLUSIVE ENTERAL NUTRITION TREATMENT IN ADULT PATIENTS WITH ACTIVE CROHN’S DISEASE

Qingfan Yang, ZiCheng Huang, Hailing Liu, Kang Chao, Xiang Gao

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COMMUNICATING NEEDS AND FEATURES OF IBD EXPERIENCES (CONFIDE) SURVEY: BURDEN AND IMPACT OF BOWEL URGENCY ON PATIENTS WITH MODERATE TO SEVERE ULCERATIVE COLITIS

Stefan Schreiber, Simon Travis, Alison Potts Bleakman, Cem Kayhan, Hilary Ellis, Theresa Hunter, Eoin Flynn, Grzegorz Suldecki, Marla Dubinsky

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CONCORDANCE BETWEEN REMISSION DEFINED BY PATIENTS VS PATIENT-REPORTED OUTCOME MEASURES IN INFLAMMATORY BOWEL DISEASE

Kendra Kamp, Chung Sang Tse, Steven Hawes, Ridhima Oberai, Alandra Weaver, Siddharth Singh, Gil Melmed, Corey Siegel, Welmoed van Deen

doi : 10.1093/ibd/izac015.128

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CROHN’S DISEASE COMPLICATED BY ILEOSIGMOID FISTULA: ASSESSMENT AND MANAGEMENT UPDATE

Sarah Benammi, Giacomo Calini, Solafah Abdalla, Kellie Mathis

doi : 10.1093/ibd/izac015.129

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EFFECTS OF DELAYED ENDOSCOPIES IN INFLAMMATORY BOWEL DISEASE PATIENTS DURING THE COVID-19 PANDEMIC

Karen Young, Devesh Hargunani, Vitaliy Poylin

doi : 10.1093/ibd/izac015.130

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ENHANCED RECOVERY PROGRAMS: HOW ARE WE BENEFITTING PATIENTS WITH IBD?

Connie Shao, Marshall McLeod, Lauren Gleason, Isabel Marques, Burke Smith, Daniel Chu

doi : 10.1093/ibd/izac015.131

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EVALUATING THE IMPACT OF THE COVID-19 PANDEMIC ON URGENT MEDICAL ACCESS FOR PATIENTS WITH INFLAMMATORY BOWEL DISEASE AT A PRIVATE COMMUNITY GASTROENTEROLOGY PRACTICE

Michelle Kwon, Chung Sang Tse, Welmoed van Deen, Michael Danielewicz, Christopher Ward, Lawrence Kogan, Firrah Saeed, Samir Shah

doi : 10.1093/ibd/izac015.132

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IBD AND THE PATIENT-PROVIDER RELATIONSHIP: DOES TRUST IMPACT TELEMEDICINE UTILIZATION?

Meghna Katta, Connie Shao, Ivan Herbey, Sagar Modi, Lauren Gleason, Isabel Marques, Teressa Duong, Elizabeth Lopez, Kaycee Hair, Daniel Chu

doi : 10.1093/ibd/izac015.133

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IBD MIMICS PRESENTED AT IBD LIVE: WHEN IT IS NOT INFLAMMATORY BOWEL DISEASE

Christopher Ward, Samir Shah, Francis Farraye, Alka Goyal, John Hanson, Stefan Holubar, Andrew Watson, Steven Wexner, David Binion, Jill Gaidos, Tracy Hull, Badr Al-Bawardy, Jana Al Hashash, Myron Brand, Tanya Bruckel, Kofi Clarke, Benjamin Cohen, Raymond Cross, Jeffrey Dueker, Sean Fine, Erin Forster, Hans Herfath, Colleen Kelly, Mark Lazarev, L Campbell Levy, Amy Lightner, Taha Qazi, Joel Rosh, Abbas Rupawala, Corey Siegel, Miguel Regueiro

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IMPLICATIONS OF ADOLESCENT AND PARENT PERCIEVED SKILL-BUILDING ON MISCARREID HELPING AND SELF-EFFICACY FOLLOWING A TRANSITION WORKSHOP FOR ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE

Malika Waschmann, Henry Lin, Jacklyn Stellway

doi : 10.1093/ibd/izac015.135

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IMPROVING THE VACCINATION RATES FOR IMMUNOSUPPRESSED PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Tony Cheng, Kyle Kreitman, Carissa Stowe, Bradford Waters, Leonard Baidoo

doi : 10.1093/ibd/izac015.136

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LOCAL IBD-EXPERTS DISSATISFACTION WITH BIOLOGIC MEDICATION AUTHORIZATION DENIALS - A SURVEY OF SPECIFIC CLINICAL SCENARIOS

Leah DeCoste, Randall Pellish

doi : 10.1093/ibd/izac015.137

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MEDICAL DECISION-MAKING AND EDUCATION RELATED TO OSTOMY SURGERY IN PEDIATRIC PATIENTS WITH IBD: QUALITATIVE THEMES FROM MULTIDISCIPLINARY PROVIDER FOCUS GROUPS

Jennie David, Jennifer Dotson, Laura Mackner

doi : 10.1093/ibd/izac015.138

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SECURE ELECTRONIC DOCUMENT SIGNING UPTAKE IN BIOLOGIC PRESCRIBING FOR IMMUNE MEDIATED DISEASES

Sowmya Sharma, Jennifer Jones, Michael Stewart

doi : 10.1093/ibd/izac015.139

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A QUALITATIVE STUDY EXPLORING MEANINGFUL IMPROVEMENT IN BOWEL URGENCY AMONG ADULTS WITH MODERATE TO SEVERE ULCERATIVE COLITIS

Louise Newton, Aiste Guobyte, Shehan McFadden, Tara Symonds, Laure Delbecque, Jill Donaldson, April Naegeli

doi : 10.1093/ibd/izac015.140

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CHANGE IN URGENCY STATUS AMONG ULCERATIVE COLITIS PATIENTS: UNDERSTANDING THE IMPACT OF TREATMENT CHANGES FROM THE COREVITAS INFLAMMATORY BOWEL DISEASE REGISTRY

Douglas Wolf, April Naegeli, Page Moore, Judson Janak, Margaux Crabtree, Mingyang Shan, Theresa Hunter, Angelina Sontag, Raymond Cross

doi : 10.1093/ibd/izac015.141

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DECONSTRUCTING DISTRESS: STAKEHOLDER ENGAGEMENT FOR EVIDENCE-BASED, PATIENT-CENTERED INTERVENTIONS FOR THE MANAGEMENT OF IBD-ASSOCIATED PSYCHOLOGICAL DISTRESS

Courtney Heisler, Noelle Rohatinsky, Michael Stewart, Michael Vallis, Tiffany Shepherd, Lori Wozney, Christine Cassidy, Barbara Currie, Kelly Phalen-Kelly, Jessica Robar, Laura Targownik, Thea Huard, Emily Neil, Jennifer Jones

doi : 10.1093/ibd/izac015.142

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EXPLORING SELF-MANAGEMENT CHALLENGES OF ADOLESCENTS AND YOUNG ADULTS WITH INFLAMMATORY BOWEL DISEASE IN AN ONLINE INSTAGRAM SUPPORT COMMUNITY

Caeli Malloy, Susan Rawl, Wendy Miller

doi : 10.1093/ibd/izac015.143

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FEAR OF THE COVID-19 PANDEMIC IN ADOLESCENTS AND YOUNG ADULTS WITH INFLAMMATORY BOWEL DISEASE: RELATIONSHIP TO PSYCHOLOGICAL AND PHYSICAL OUTCOMES

Nicole Neiman, Kavya Anjur, Ann Ming Yeh, Rachel Bensen, Anava Wren

doi : 10.1093/ibd/izac015.144

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FECAL CALPROTECTIN TESTING: AN INVESTIGATION OF PATIENT COMPLIANCE AND PERCEPTIONS

Courtney Perry, Mahmoud Hashim, Ahmed Elmoursi, Ahmed Elkheshen, Adam Dugan, Deborah Flomenhoft, Amy Stuffelbeam, Terrence Barrett

doi : 10.1093/ibd/izac015.145

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IDENTIFYING BARRIERS TO HEALTH MAINTENANCE IN MEDICALLY-UNDERSERVED PATIENTS WITH IBD: A QUALITATIVE STUDY

Juanita Belton, Natalie Sanfratello, Erika Gaitan, Alana LeBron, Sharmeel Wasan, Julie White, Alan Moss

doi : 10.1093/ibd/izac015.146

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INCREASED PREVALENCE OF ANXIETY IN HOSPITALIZED CROHN’S DISEASE PATIENTS IN THE UNITED STATES: INSIGHTS FROM NATIONAL INPATIENT DATABASE FROM 2009 TO 2018

Abhishek Bhurwal, Hemant Mutneja, Sophia Pimpinelli, Marcella Pimpinelli, Darren Seril

doi : 10.1093/ibd/izac015.147

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LONGITUDINAL STUDY OF THE IMPACT OF HEALTH CONFIDENCE ON INFLAMMATORY BOWEL DISEASE OUTCOMES AND HEALTHCARE UTILIZATION

Chung Sang Tse, Gil Melmed, Chien-Hsiang Weng, Samir Shah, Alandra Weaver, Brant Oliver, Glyn Elwyn, Corey Siegel, Welmoed van Deen

doi : 10.1093/ibd/izac015.148

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PATIENTS’ PERSPECTIVES, EXPERIENCES, AND CONCERNS WITH CROHN’S PERIANAL FISTULAE: INSIGHTS FROM SOCIAL MEDIA PLATFORMS

Carine Khalil, Welmoed van Deen, Taylor Dupuy, Gaurav Syal, Corey Arnold, Susan Cazzetta, Pradeep Nazarey, Brennan Spiegel

doi : 10.1093/ibd/izac015.149

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PEOPLE WITH IBD WANT TO TALK ABOUT SLEEP: RECOMMENDATIONS ON WHAT TO ASK AND HOW TO RESPOND TO SLEEP COMPLAINTS

Jessica Salwen-Deremer, Christina Jagielski, Michael Smith, Corey Siegel

doi : 10.1093/ibd/izac015.150

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PREVALENCE AND IMPACTS OF POST-TRAUMATIC STRESS SYMPTOMS IN IBD PATIENTS FROM UNDER-REPRESENTED MINORY GROUPS

Josie McGarva, Tiffany Taft

doi : 10.1093/ibd/izac015.151

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PROMOTING AT-HOME DISEASE MANAGEMENT OF IBD WITH A MULTIDISCIPLINARY DIGITAL THERAPY APP: SHORT-TERM RESULTS

Roeland Pater, Dandyano Zentveld, Lisa Booth

doi : 10.1093/ibd/izac015.152

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REDEFINING HEALTHCARE: A NOVEL, SCIENCE-BASED, EXPERIENTIAL FRAMEWORK FOR IMPROVING PATIENT OUTCOMES IN INFLAMMATORY BOWEL DISEASE

Amanda Puckett, Amy Loftus, Andrew Kornfeld

doi : 10.1093/ibd/izac015.153

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SELF-RATED HEALTH IN INFLAMMATORY BOWEL DISEASE CORRELATES WITH ANXIETY, DEPRESSION, CATASTROPHIC THINKING, AND DISEASE SEVERITY

Brooke Palmer, Megan Petrik, Kathryn Tomasino

doi : 10.1093/ibd/izac015.154

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SEXUAL DYSFUNCTION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Magdalena Kaniewska, Konrad Lewandowski, Dorota Szydlarska, Grazyna Rydzewska

doi : 10.1093/ibd/izac015.155

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STIGMA INTERNALIZATION IN NON-WHITE PATIENTS WITH IBD AND ITS RELATIONSHIP WITH PATIENT OUTCOMES

Nicolette Veracruz, Tiffany Taft

doi : 10.1093/ibd/izac015.156

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STIGMA PERCEPTIONS IN NON-WHITE IBD PATIENTS AND RELATIONSHIPS WITH PATIENT OUTCOMES

Nicolette Veracruz, Tiffany Taft

doi : 10.1093/ibd/izac015.157

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THE CROHN’S AND COLITIS DISTRESS SCALE: ASSESSING THE DOMAINS OF IMPACT IN YOUTH WITH IBD

Caroline Cummings, Jacklyn Stellway, Jennifer Paternostro, Maggie Stoeckel, Linda Muir, Michael Harris

doi : 10.1093/ibd/izac015.158

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TRANSPORTATION ACCESS AND DELAY IN DIAGNOSIS FOR PEDIATRIC INFLAMMATORY BOWEL DISEASE PATIENTS

Nicole Zeky, Colleen LeBlanc, Elizabeth McDonough, Dedrick Moulton

doi : 10.1093/ibd/izac015.159

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BIOLOGIC PRECISION DOSING IS NOW AVAILABLE AT THE BEDSIDE FOR CHILDREN AND ADULTS WITH INFLAMMATORY BOWEL DISEASE RECEIVING INFLIXIMAB

Phillip Minar, Abigail Samuels, Tomoyuki Mizuno, Frank Menke, Aaron Vogt, Nieko Punt, Alexander Vinks

doi : 10.1093/ibd/izac015.160

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PREDICTIVE PERFORMANCE OF DIFFERENT POPULATION PHARMACOKINETIC MODELS IN A REAL-WORLD COHORT OF CROHN’S DISEASE PATIENTS

Abigail Samuels, Nieko Punt, Jack Reifenberg, Tomoyuki Mizuno, Ruben Colman, Frank Menke, Aaron Vogt, Alexander Vinks, Phillip Minar

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REAL-WORLD VEDOLIZUMAB PHARMACOKINETIC STUDY IN CHILDREN IDENTIFIES TWO NOVEL BIOMARKERS OF DRUG CLEARANCE

Ruben Colman, Tomoyuki Mizuno, Jeffrey Hyams, Joshua Noe, Brendan Boyle, Lee Denson, Alexander Vinks, Phillip Minar

doi : 10.1093/ibd/izac015.162

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AN ONLINE SURVEY AMONG US PATIENTS WITH IMMUNE-MEDIATED CONDITIONS: BELIEFS ABOUT BIOSIMILARS FROM PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Gary Jacobson, Allan Gibofsky, Shannan O’Hara-Levi, Archie Franklin, Laurent Peyrin-Biroulet, Melissa McGrath, Dorothy McCabe

doi : 10.1093/ibd/izac015.163

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ANTI-SARS-COV-2 VACCINATION AND ANTIBODY RESPONSE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE ON IMMUNE-MODIFYING THERAPY. PROSPECTIVE SINGLE TERTIARY CENTER STUDY ON 602 IBD PATIENTS

Karin Cerna, Dana Duricova, Martin Lukas, Nadezda Machkova, Veronika Hruba, Milan Lukas

doi : 10.1093/ibd/izac015.164

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BEZLOTOXUMAB THERAPY FOR RECURRENT CLOSTRIDIUM DIFFICILE INFECTION IN AN ULCERATIVE COLITIS PATIENT

Aaron Fein, Cody Kern, Rana Mohamed, Terrence Barrett, Courtney Perry

doi : 10.1093/ibd/izac015.165

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BIOLOGICAL THERAPY AND POST-OPERATIVE OUTCOMES IN CROHN’S DISEASE PATIENTS UNDERGOING REPEAT ILEOCOLIC RESECTION

Nir Horesh, Michael Freund, Zoe Garoufalia, Rachel Gefen, David Zhang, Timothy Smith, Steven Wexner

doi : 10.1093/ibd/izac015.166

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COMBINATION BIOLOGIC AND SMALL MOLECULE THERAPY FOR REFRACTORY ULCERATIVE COLITIS

Kaitlyn Hickman, Ronald Jordan, William Sonnier

doi : 10.1093/ibd/izac015.167

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COMBINATION USTEKINUMAB AND VEDOLIZUMAB THERAPY FOR REFRACTORY INFLAMMATORY BOWEL DISEASE: A SINGLE INSTITUTION CASE SERIES

Nabila Dawoud, Lucas Roy, Ahmed Elmoursi, Mahmoud Elkammar, Mohamed Eltaher, Terrence Barrett, Courtney Perry

doi : 10.1093/ibd/izac015.168

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COVID-19 INFECTIONS IN VACCINATED PATIENTS WITH INFLAMMATORY BOWEL DISEASE: OUTCOMES AND RISK FACTORS FOR SEVERE DISEASE

Emily Spiera, Danielle Ganjian, Xian Zhang, Erica Brenner, Manasi Agrawal, Jean-Frederic Colombel, Michael Kappelman, Asher Kornbluth, Ryan Ungaro

doi : 10.1093/ibd/izac015.169

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DUAL BIOLOGICAL OR SMALL MOLECULE TREATMENT IN INFLAMMATORY BOWEL DISEASES: DATA FROM CLINICAL PRACTICE

Milan Lukas, Martin Kolar, Martin Vasatko, Martin Lukas, Dana Duricova, Nadezda Machkova, Veronika Hruba, Karin Cerna, Kristyna Kastylova, Kristyna Kubickova

doi : 10.1093/ibd/izac015.170

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EARLY VERSUS DELAYED INITIATION OF VEDOLIZUMAB IN ULCERATIVE COLITIS: TREATMENT RESPONSE IN THE REAL WORLD (RALEE)

Noa Cleveland, Ninfa Candela, John Carter, Maja Kuharic, Joyce Qian, Lily Tang, Robin Turpin, David Rubin

doi : 10.1093/ibd/izac015.171

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EFFICACY OF LOW DOSE NALTREXONE IN PATIENTS WITH CROHN’S COLITIS AND ILEITIS

Leonard Weinstock

doi : 10.1093/ibd/izac015.172

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HIGH DOSE TOFACITINIB AS SALVAGE THERAPY IN STEROID REFRACTORY ACUTE SEVERE ULCERATIVE COLITIS FOLLOWING NON-RESPONSE TO INFLIXIMAB

Muhammad Khan, Kamran Mushtaq, Rafie Yakoob, Deema AlSoub

doi : 10.1093/ibd/izac015.173

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IMPACT OF THIOPURINE DOSE IN COMBINATION THERAPY IN INFLAMMATORY BOWEL DISEASE

Ahmad Nawaz, Laura Glick, Darrick Li, Jill Gaidos, Deborah Proctor, Badr Al-Bawardy

doi : 10.1093/ibd/izac015.174

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REAL WORLD EFFECTIVENESS AND SAFETY OF OZANIMOD: INITIAL RESULTS FROM A LARGE TERTIARY CENTER

Nathaniel Cohen, Tenzin Choden, David Choi, Noa Cleveland, Russell Cohen, Sushila Dalal, Atsushi Sakuraba, Ira Hanan, David Rubin

doi : 10.1093/ibd/izac015.175

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REAL-WORLD UTILIZATION OF ADALIMUMAB BIOSIMILAR (ABP 501) IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN EUROPE

Ran Jin, Chidozie Nduka, Delphine Courmier, Hannah Knight, Rachael Meadows, James Piercy, Waldemar Radziszewski

doi : 10.1093/ibd/izac015.176

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SUCCESSFUL CLEARANCE OF CYTOMEGALOVIRUS COLITIS IN ACUTE SEVERE ULCERATIVE COLITIS DURING INDUCTION OF OZANIMOD

Rana Mohamed, Cody Kern, Aaron Fein, Terrence Barrett, Courtney Perry

doi : 10.1093/ibd/izac015.177

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VEDOLIZUMAB AS TREATMENT FOR COMMON VARIABLE IMMUNE DEFICIENCY (CVID): A CASE SERIES AND BRIEF REVIEW OF THE LITERATURE

Sagar Patel, Cameron Wilhoit, Kelli Williams, Erin Forster

doi : 10.1093/ibd/izac015.178

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VEDOLIZUMAB FOR REFRACTORY MICROSCOPIC COLITIS: A CASE SERIES

Nabila Dawoud, Aaron Fein, Mahmoud Elkammar, Mohamed Eltaher, Terrence Barrett, Courtney Perry

doi : 10.1093/ibd/izac015.179

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WITHDRAWN: EFFICACY, SAFETY, AND TOLERABILITY OF OMILANCOR IN A PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF PATIENTS WITH ULCERATIVE COLITIS

Andrew Leber, Raquel Hontecillas, Nuria Tubau-Juni, Simon Lichtiger, Josep Bassaganya-Riera

doi : 10.1093/ibd/izac015.180

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