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Several faces of refractory coeliac disease type 2 (30 March, 2021)

Joseph A Murray

doi : 10.1136/gutjnl-2021-324251

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Artificial intelligence in GI endoscopy: stumbling blocks, gold standards and the role of endoscopy societies (21 January, 2021)

Rüdiger Schmitz, Rene Werner, Alessandro Repici, Raf Bisschops, Alexander Meining, Michael Zornow, Helmut Messmann, Cesare Hassan, Prateek Sharma, Thomas R?sch

doi : 10.1136/gutjnl-2020-323115

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End of the story: direct-acting antiviral agents are not associated with recurrence of hepatocellular carcinoma (30 March, 2021)

Ruben Hernaez, Robert Thimme

doi : 10.1136/gutjnl-2021-324288

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Original research: Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

Paul Oster, Laurie Vaillant, Erika Riva, Brynn McMillan, Christina Begka, Caroline Truntzer, Corentin Richard, Marine M Leblond, Meriem Messaoudene, Elisavet Machremi, Emeric Limagne, Francois Ghiringhelli, Bertrand Routy, Gregory Verdeil, Dominique Velin

doi : 10.1136/gutjnl-2020-323392

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Original research: Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency

Xiaochuan Dong, Shumei Song, Yuan Li, Yibo Fan, Lulu Wang, Ruiping Wang, Longfei Huo, Ailing Scott, Yan Xu, Melissa Pool Pizzi, Lang Ma, Ying Wang, Jiangkang Jin, Wei Zhao, Xiaodan Yao, Randy L Johnson, Linghua Wang, Zhenning Wang, Guang Peng, Jaffer A Ajani

doi : 10.1136/gutjnl-2020-322660

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Original research: International consensus to standardise histopathological scoring for small bowel strictures in Crohn’s disease

Ilyssa O Gordon, Dominik Bettenworth, Arne Bokemeyer, Amitabh Srivastava, Christophe Rosty, Gert de Hertogh, Marie E Robert, Mark A Valasek, Ren Mao, Jiannan Li, Noam Harpaz, Paula Borralho, Reetesh K Pai, Robert Odze, Roger Feakins, Claire E Parker, Leonardo Guizzetti, Tran Nguyen, Lisa M Shackelton, William J Sandborn, Vipul Jairath, Mark Baker, David Bruining, Joel G Fletcher, Brian G Feagan, Rish K Pai, Florian Rieder

doi : 10.1136/gutjnl-2021-324374

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Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum

Takashi Nagaishi, Taro Watabe, Kunihiko Kotake, Toshihiko Kumazawa, Tomomi Aida, Kohichi Tanaka, Ryuichi Ono, Fumitoshi Ishino, Takako Usami, Takamasa Miura, Satomi Hirakata, Hiroko Kawasaki, Naoya Tsugawa, Daiki Yamada, Kazuhiro Hirayama, Soichiro Yoshikawa, Hajime Karasuyama, Ryuichi Okamoto, Mamoru Watanabe, Richard S Blumberg, Takahiro Adachi

doi : 10.1136/gutjnl-2020-322873

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Original research: Oncogenetic landscape of lymphomagenesis in coeliac disease

Sascha Cording, Ludovic Lhermitte, Georgia Malamut, Sofia Berrabah, Amélie Trinquand, Nicolas Guegan, Patrick Villarese, Sophie Kaltenbach, Bertrand Meresse, Sherine Khater, Michael Dussiot, Marc Bras, Morgane Cheminant, Bruno Tesson, Christine Bole-Feysot, Julie Bruneau, Thierry Jo Molina, David Sibon, Elizabeth Macintyre, Olivier Hermine, Christophe Cellier, Vahid Asnafi, Nadine Cerf-Bensussan

doi : 10.1136/gutjnl-2020-322935

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Original research: Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

Ester Pagano, Joshua E Elias, Georg Schneditz, Svetlana Saveljeva, Lorraine M Holland, Francesca Borrelli, Tom H Karlsen, Arthur Kaser, Nicole C Kaneider

doi : 10.1136/gutjnl-2020-323363

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Original research: Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade

Wei Si, Hua Liang, Jason Bugno, Qi Xu, Xingchen Ding, Kaiting Yang, Yanbin Fu, Ralph R Weichselbaum, Xin Zhao, Liangliang Wang

doi : 10.1136/gutjnl-2020-323426

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Original research: Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice

Tiphaine Le Roy, Emilie Moens de Hase, Matthias Van Hul, Adrien Paquot, Rudy Pelicaen, Marion Régnier, Clara Depommier, Céline Druart, Amandine Everard, Dominique Maiter, Nathalie M Delzenne, Laure B Bindels, Marie de Barsy, Audrey Loumaye, Michel P Hermans, Jean-Paul Thissen, Sara Vieira-Silva, Gwen Falony, Jeroen Raes, Giulio G Muccioli, Patrice D Cani

doi : 10.1136/gutjnl-2020-323778

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Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome

Qin Liu, Joyce Wing Yan Mak, Qi Su, Yun Kit Yeoh, Grace Chung-Yan Lui, Susanna So Shan Ng, Fen Zhang, Amy Y L Li, Wenqi Lu, David Shu-Cheong Hui, Paul KS Chan, Francis K L Chan, Siew C Ng

doi : 10.1136/gutjnl-2021-325989

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Original research: Linked Colour imaging for the detection of polyps in patients with Lynch syndrome: a multicentre, parallel randomised controlled trial

Britt B S L Houwen, Yark Hazewinkel, Mar?a Pellisé, Liseth Rivero-S?nchez, Francesc Balaguer, Raf Bisschops, Sabine Tejpar, Alessandro Repici, D Ramsoekh, Maarten A J M Jacobs, Ramon-Michel M Schreuder, Michal Filip Kaminski, Maria Rupinska, Pradeep Bhandari, Martijn G H van Oijen, Lianne Koens, Barbara A J Bastiaansen, Kristien M Tytgat, Paul Fockens, Jasper L A Vleugels, E Dekker

doi : 10.1136/gutjnl-2020-323132

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Original research: Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer 

Manuel Zorzi, Jessica Battagello, Kevin Selby, Giulia Capodaglio, Susanna Baracco, Silvia Rizzato, Enrico Chinellato, Stefano Guzzinati, Massimo Rugge

doi : 10.1136/gutjnl-2020-322192

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Original research: Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment

Zhibo Xie, Ya Gao, Chiakang Ho, Lequn Li, Chen Jin, Xiaoyi Wang, Caifeng Zou, Yishen Mao, Xiaobo Wang, Qingfeng Li, Deliang Fu, Yi-Fan Zhang

doi : 10.1136/gutjnl-2020-323014

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Original research: Novel pathomechanism for spontaneous bacterial peritonitis: disruption of cell junctions by cellular and bacterial proteases

Marika Haderer, Philip Neubert, Eva Rinner, Annika Scholtis, Lucile Broncy, Heidi Gschwendtner, Arne Kandulski, Vlad Pavel, Alexander Mehrl, Christoph Brochhausen, Sophie Schlosser, Karsten Gülow, Claudia Kunst, Martina Müller

doi : 10.1136/gutjnl-2020-321663

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Original research: Hepatocellular carcinoma recurrence after direct-acting antiviral therapy: an individual patient data meta-analysis

Victor Sapena, Marco Enea, Ferran Torres, Ciro Celsa, Jose Rios, Giacomo Emanuele Maria Rizzo, Pierre Nahon, Zoe Mari?o, Ryosuke Tateishi, Tatsuya Minami, Angelo Sangiovanni, Xavier Forns, Hidenori Toyoda, Stefano Brillanti, Fabio Conti, Elisabetta Degasperi, Ming-Lung Yu, Pei-Chien Tsai, Kevin Jean, Mohamed El Kassas, Hend Ibrahim Shousha, Ashraf Omar, Claudio Zavaglia, Hiroko Nagata, Mina Nakagawa, Yasuhiro Asahina, Amit G Singal, Caitlin Murphy, Mohamed Kohla, Chiara Masetti, Jean-François Dufour, Nicolas Merchante, Luisa Cavalletto, liliana LC chemello, Stanislas POL, Javier Crespo, Jose Luis Calleja, Rosanna Villani, Gaetano Serviddio, Alberto Zanetto, Sarah Shalaby, Francesco Paolo Russo, Rob Bielen, Franco Trevisani, Calogero Cammà, Jordi Bruix, Giuseppe Cabibbo, Maria Reig

doi : 10.1136/gutjnl-2020-323663

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Original research: Impaired antibacterial response of liver sinusoidal V?9+V?2+ T cells in patients with chronic liver disease

Min-Seok Rha, Ji Won Han, June-Young Koh, Ha Seok Lee, Jong Hoon Kim, Kyungjoo Cho, Soon Il Kim, Myoung Soo Kim, Jae Geun Lee, Su-Hyung Park, Dong Jin Joo, Jun Yong Park, Eui-Cheol Shin

doi : 10.1136/gutjnl-2020-322182

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Original research: Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma (9 February, 2021) 

Camille Péneau, Sandrine Imbeaud, Tiziana La Bella, Theo Z Hirsch, Stefano Caruso, Julien Calderaro, Valerie Paradis, Jean-Frederic Blanc, Eric Letouzé, Jean-Charles Nault, Giuliana Amaddeo, Jessica Zucman-Rossi

doi : 10.1136/gutjnl-2020-323153

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Original research: HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4 (8 April, 2021) 

Long V. Pham, Martin Schou Pedersen, Ulrik Fahn?e, Carlota Fernandez-Antunez, Daryl Humes, Kristian Sch?nning, Santseharay Ramirez, Jens Bukh

doi : 10.1136/gutjnl-2020-323585

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Cross-roads for meta-analysis and network meta-analysis of H. pylori therapy

David Y Graham, Ruben Hernaez, Theodore Rokkas

doi : 10.1136/gutjnl-2021-326170

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GI highlights from the literature (8 February, 2022)

Philip J Smith

doi : 10.1136/gutjnl-2022-327000

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Letter: Colonoscopic polypectomy in patients on anticoagulation: time to embrace the cold revolution?

Nicholas McDonald, Saurabh Chandan, Mohammad Bilal

doi : 10.1136/gutjnl-2021-324790

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Letter: Appendoscopy in patients with serrated polyposis syndrome (8 April, 2021)

Rachel Hallit, Maximilien Barret, Arthur Belle, Einas Abou Ali, Marion Dhooge, Romain Coriat, Stanislas Chaussade

doi : 10.1136/gutjnl-2021-324679

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Letter: Endoscopic ultrasound-guided liver biopsy: down but not out (13 April, 2021)

Nadeem Akhter Tehami, Keith Siau, Ryan Buchanan, Eleanor Jaynes, Ben Maher

doi : 10.1136/gutjnl-2021-324815

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Letter: Reducing low risk of transmissible infection in duodenoscopes: at what cost to the planet? (10 May, 2021)

Anjan Dhar, Bu'Hussain Hayee, Emma Wesley, William Stableforth, Shaji Sebastian

doi : 10.1136/gutjnl-2021-324821

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Letter: SARS-CoV-2 in endoscopy: a potential way of microorganisms’ air transmission (5 May, 2021) 

Stanislas Chaussade, Rachel Hallit, Einas Abou Ali, Arthur Belle, Maximilien Barret, Romain Coriat

doi : 10.1136/gutjnl-2021-324934

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Letter: Reply to: “Acute-on-chronic liver failure in East-Asia: an underestimated issue with limited data” (12 May, 2021)

Adrià Juanola, Gabriel Mezzano, James P Hamilton, Pere Ginès, Elsa Solà, Ruben Hernaez

doi : 10.1136/gutjnl-2021-324926

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A rare cause of dyspeptic symptoms and anaemia in a young man (6 October, 2020)

Hareem Rehman, Shahab Abid, Naila Kayani, Ali Haroon

doi : 10.1136/gutjnl-2020-322511

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