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Evaluation of the effect of scaling and root planing on salivary and serum fetuin-A levels in patients with Stages II and III periodontitis
Sanjita Nair, KJ Nisha
doi : 10.1002/JPER.21-0179
Pages: 179-188 First Published:16 May 2021
Fetuin-A has garnered recognition in the etiopathogenesis of several systemic disorders. It has been recently acknowledged as an anti-inflammatory marker for periodontal disease. This study aimed to compare and correlate salivary and serum fetuin-A levels in health and patients with stages II-III periodontitis along with evaluating the effect of non-surgical periodontal therapy (NSPT) on the same.
Ultrasonographic evaluation of the titanium-prepared platelet-rich fibrin effect in free gingival graft procedures
Revan Birke Koca-Ünsal, Gürkan Ünsal, Gökhan Kasnak, Yiğit Fıratlı, İlknur Özcan, Kaan Orhan, Erhan Fıratlı
doi : 10.1002/JPER.21-0076
Pages: 189-196 First Published:31 May 2021
Complications after free gingival graft (FGG) operations are generally related to the donor site. The titanium-prepared, platelet-rich fibrin (T-PRF) placement in the donor site accelerate the wound healing and prevent postoperative complications such as pain and hemorrhage. We aim to evaluate the effect of T-PRF regarding vascularization and tissue thickness and to report the advantages of the ultrasonography (US) in FGG.
Surgical reconstructive treatment for infraosseous peri-implantitis defects with a submerged healing approach: A prospective controlled study
Shih-Cheng Wen, Shayan Barootchi, Wen-Xia Huang, Hom-Lay Wang
doi : 10.1002/JPER.21-0161
Pages: 197-209 First Published:29 May 2021
The aim of this study was to assess the reconstructive potential of a submerged healing approach for the treatment of infraosseous peri-implantitis defects.
Sleep time and duration are associated with periodontitis in a representative sample of Koreans
Dong-Hun Han, Mi-Sun Kim, Seohee Kim, Ji-Won Yoo, Jay J. Shen
doi : 10.1002/JPER.20-0252
Pages: 210-219 First Published:26 May 2021
So far, studies on the association between sleep and periodontitis have shown conflicting results. This study assessed the association among sleep duration, sleep time, and periodontitis among a nationally representative Korean population and the mediation effect of WBC.
Periodontal health education session can improve oral hygiene in patients with gingivitis: A masked randomized controlled clinical study
Sadiye Gunpinar, Bilge Meraci
doi : 10.1002/JPER.21-0034
Pages: 220-230 First Published:28 May 2021
The aim of this clinical trial was to evaluate the effect of a periodontal health education session (PHES), which included education on the pathogenesis and consequences of periodontal diseases on oral hygiene motivation in patients with gingivitis.
Long-term stability of adjunctive use of enamel matrix protein derivative on porcine-derived xenograft for the treatment of one-wall intrabony defects: A 4-year extended follow-up of a randomized controlled trial
Jae-Hong Lee, Seong-Nyum Jeong
doi : 10.1002/JPER.21-0254
Pages: 231-238 First Published:29 May 2021
The long-term outcomes of demineralized porcine bone matrix (DPBM) in combination with enamel matrix protein derivative (EMD) for the treatment of one-wall intrabony defects have not yet been evaluated. Therefore, this study aimed to assess the clinical, radiographic, and patient-reported outcomes of regenerative therapy using DPBM with EMD (test group) in comparison with DPBM alone (control group) for the treatment of one-wall intrabony defects in the molar regions.
Effect of intravenous dexamethasone on postoperative pain and swelling following periodontal flap surgery: A randomized controlled trial of patient-centered outcomes
Michael P. Vieth, David E. Deas, A. Archontia Palaiologou, Anibal Diogenes, Michael J. Mader, Brian L. Mealey
doi : 10.1002/JPER.21-0153
Pages: 239-247 First Published:22 May 2021
This randomized, crossover trial sought to determine if a preoperative intravenous (IV) dose of dexamethasone reduces pain, swelling, and analgesic usage following periodontal surgery.
Bioactive glass and arginine dentifrices immediately relieved dentine hypersensitivity following non-surgical periodontal therapy: A randomized controlled trial
Napassorn Ongphichetmetha, Attawood Lertpimonchai, Chantrakorn Champaiboon
doi : 10.1002/JPER.21-0091
Pages: 248-257 First Published:01 June 2021
There is no report concerning calcium sodium phosphosilicate (CSPS) and arginine dentifrices in reducing dentine hypersensitivity (DH) in patients undergoing non-surgical periodontal therapy. The aim of the study was to compare the efficacy of a dentifrice containing bioactive glass, 5% CSPS, and 8% arginine dentifrice in relieving DH in patients undergoing non-surgical therapy.
Metformin accelerates wound healing by Akt phosphorylation of gingival fibroblasts in insulin-resistant prediabetes mice
Hiromi Kominato, Kohei Takeda, Koji Mizutani, Risako Mikami, Daisuke Kido, Prima Buranasin, Natsumi Saito, Shu Takemura, Keita Nakagawa, Toshiyuki Nagasawa, Takanori Iwata
doi : 10.1002/JPER.21-0362
Pages: 258-270 First Published:24 August 2021
This study aimed to investigate the effects of metformin on gingival wound healing in insulin-resistant prediabetes.
Cytokines regulate stemness of mesenchymal stem cells via miR-628-5p during periodontal regeneration
Tomoyuki Iwata, Noriyoshi Mizuno, Takayoshi Nagahara, Eri Kaneda-Ikeda, Mikihito Kajiya, Shinya Sasaki, Katsuhiro Takeda, Mari Kiyota, Ryoichi Yagi, Tsuyoshi Fujita, Hidemi Kurihara
doi : 10.1002/JPER.21-0064
Pages: 271-288 First Published:21 June 2021
Cytokines play key roles in stimulating periodontal regeneration; however, their exact mechanisms of action remain unclear. Mesenchymal stem cells (MSCs) are multipotent cells that have self-renewal abilities and can differentiate into periodontal tissues such as bone, cementum, and periodontal ligaments following transplantation, like periodontal progenitor cells. Here, we used MSCs to identify the regulatory genes induced by periodontal regenerative cytokines.
Microvesicles, blood cells, and endothelial cells mediate phosphatidylserine-related prothrombotic state in patients with periodontitis
Nan Zuo, Wenhui Liu, Tenglong Hu, Yingmiao Liu, Baorong Li, Huan Liu, Haijiao Jing, Xiaojing Chen, Yueyue Li, Jingwen Du, Tianshui Hu, Zengxiang Dong, Yumei Niu, Jialan Shi
doi : 10.1002/JPER.21-0025
Pages: 289-299 First Published:22 June 2021
Phosphatidylserine (PS) is essential for inflammation-associated thrombogenesis, but the exact effect of PS on the prothrombotic state in periodontitis is uncertain. This study aimed to determine the PS-related procoagulant state in patients with periodontitis.
Preemptive effects of ibuprofen and nimesulide on postoperative pain control after open flap periodontal surgeries: A randomized placebo-controlled split-mouth clinical trial
Bianca F. E. Santos, Fernando O. Costa, Andrea M. A. Vasconcelos, Renata M. Cyrino, LuÃs O. M. Cota
doi : 10.1002/JPER.20-0887
Pages: 300-309 First Published:24 May 2021
Data on preemptive analgesia in periodontal surgeries are scarce and still diverse. The aim of this study was to evaluate and compare the analgesic effects of the preemptive administration of ibuprofen and nimesulide in open flap periodontal surgeries.
Effects of infrared light laser therapy on in vivo and in vitro periodontitis models
Gabriela Alessandra da Cruz Galhardo Camargo, Lucas Mota de Oliveira Barbosa, Milla Bonecini Stumbo, Julio Cesar Thurler Júnior, Gabriella Ribeiro Machado da Costa, Andréa de Castro Domingos-Vieira, Vinicius D'Avila Bitencourt Pascoal, Bruno Kaufmann Robbs, Ricardo Tadeu Lopes, Olga Maria Oliveira de Araujo, Luciane Portas Capelo
doi : 10.1002/JPER.20-0842
Pages: 310-321 First Published:29 May 2021
This study evaluated the effects of infrared light laser therapy (ILLT) on ligature-induced periodontitis in rats using micro-computed tomography (micro-CT), histology, fibroblast migration, and viability analysis.
The use of probiotics can reduce the severity of experimental periodontitis in rats with metabolic syndrome: An immunoenzymatic and microtomographic study
Giselle A. Silva, André L. G. Moreira, Pedro H. F. Silva, Sérgio L. Salvador, Renato C. V. Casarin, Raphael M. Vicente, Graziele C. Ferreira, José E. Tanus-Santos, Flávia A. C. Furlaneto, Michel R. Messora
doi : 10.1002/JPER.21-0285
Pages: e1-e12 First Published:09 August 2021
This study evaluated the effects of Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) in the development of periodontitis (PE), associated or not with metabolic syndrome, (MS) in rats.
Osteopontin induces osteogenic differentiation by human periodontal ligament cells via calcium binding domain–ALK-1 interaction
Daneeya Chaikiawkeaw, Narach Khorattanakulchai, Ketsaraporn Nammultriputtar, Kaewta Rattanapisit, Vincent Everts, Anchanee Kubera, Waranyoo Phoolcharoen, Prasit Pavasant
doi : 10.1002/JPER.21-0184
Pages: e13-e23 First Published:28 August 2021
Recently we have generated recombinant human osteopontin (rhOPN) using a plant platform (Nicotiana benthamiana) and demonstrated, when coated on culture plates, its osteogenic induction capacity of human periodontal ligament (PDL) cells. The aim of this study is to elucidate the molecular mechanism underlying the rhOPN-induced osteogenic differentiation of human PDL cells.
An in vitro comparison of four antibacterial agents with and without nicotine and their effects on human gingival fibroblasts
Chandni Batra, Marwa Alalshaikh, Richard L. Gregory, L. Jack Windsor, Steven B. Blanchard, Yusuke Hamada
doi : 10.1002/JPER.21-0262
Pages: e24-e33 First Published:02 December 2021
The purpose of the study was to compare anti-bacterial activity of 0.12% chlorhexidine (CHX), 10% povidone iodine (PVD), Vega oral care gel (VEGA), and antioxidant gel (AO) on Streptococcus mutans, Streptococcus sanguis, Fusobacterium nucleatum, and Porphyromonas gingivalis with and without nicotine and to evaluate their effects on human gingival fibroblasts (HGFs).
Balint Orban Memorial Program Abstracts
doi : 10.1002/JPER.21-0584
Pages: e34-e45 First Published:14 October 2021
Research Forum Poster Session and Competition: Winners
doi : 10.1002/JPER.21-0581
Pages: e46-e48 First Published:04 October 2021
Research Forum Poster Session and Competition: Finalists and Posters
doi : 10.1002/JPER.21-0580
Pages: e49-e59 First Published:17 November 2021
