British Journal of Anaesthesia




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Editorial Board

doi : 10.1016/S0007-0912(20)30966-1

Volume 126, Issue 1, January 2021, Page i

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Associate Editorial Board

doi : 10.1016/S0007-0912(20)30967-3

Volume 126, Issue 1, January 2021, Page ii

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Contents

doi : 10.1016/S0007-0912(20)30969-7

Volume 126, Issue 1, January 2021, Pages iv-viii

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Turning ‘waiting lists’ for elective surgery into ‘preparation lists’

Nicholas Levy, David A. Selwyn, Dileep N. Lobo

doi : 10.1016/j.bja.2020.08.021

Volume 126, Issue 1, January 2021, Pages 1-5

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Bleeding, anaemia, and transfusion: an ounce of prevention is worth a pound of cure

Steven M. Frank, Melissa M. Cushing

doi : 10.1016/j.bja.2020.09.009

Volume 126, Issue 1, January 2021, Pages 5-9

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Intravenous iron administered to anaemic patients before surgery and hospital readmission in the PREVENTT study: one answer, a potentially important health benefit, and new questions

Patrick Meybohm, David M. Baron, Peter Kranke

doi : 10.1016/j.bja.2020.09.010

Volume 126, Issue 1, January 2021, Pages 9-11

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Tranexamic acid and trauma coagulopathy: where are we now?

Ciara Hanley, Jeannie Callum, Angela Jerath

doi : 10.1016/j.bja.2020.09.014

Volume 126, Issue 1, January 2021, Pages 12-17

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Intramuscular tranexamic acid: a real-world application of pharmacokinetics

Andrea Cortegiani, Anthony R. Absalom, Beverley J. Hunt

doi : 10.1016/j.bja.2020.10.003

Volume 126, Issue 1, January 2021, Pages 17-20

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Comparative videolaryngoscope performance in children: data from the Pediatric Difficult Intubation Registry

Andrew Norris, James Armstrong

doi : 10.1016/j.bja.2020.08.031

Volume 126, Issue 1, January 2021, Pages 20-22

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Ultrasound identification of the cricothyroid membrane: the new standard in preparing for front-of-neck airway access

Michael S. Kristensen, Wendy H. Teoh

doi : 10.1016/j.bja.2020.10.004

Volume 126, Issue 1, January 2021, Pages 22-27

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Occam's razor at the sharp end: simplified preoperative risk assessment

Simon J. Davies, Gary Minto

doi : 10.1016/j.bja.2020.09.015

Volume 126, Issue 1, January 2021, Pages 27-30

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Resisting neural inertia: an exercise in floccinaucinihilipilification?

Douglas J. Eleveld, Pieter J. Colin, Anthony R. Absalom, Michel M.R.F. Struys

doi : 10.1016/j.bja.2020.09.025

Volume 126, Issue 1, January 2021, Pages 31-34

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Anaesthetic-induced developmental neurotoxicity on (neuro)steroids

Alex S. Evers

doi : 10.1016/j.bja.2020.08.008

Volume 126, Issue 1, January 2021, Pages 34-37

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Predictive coding as a model of sensory disconnection: relevance to anaesthetic mechanisms

Robert D. Sanders, Cameron Casey, Yuri B. Saalmann

doi : 10.1016/j.bja.2020.08.017

Volume 126, Issue 1, January 2021, Pages 37-40

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Argon: a noble, but not inert, treatment for brain trauma?

Christopher J. Edge, Robert Dickinson

doi : 10.1016/j.bja.2020.09.028

Volume 126, Issue 1, January 2021, Pages 41-43

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The ‘third wave’: impending cognitive and functional decline in COVID-19 survivors

Hanan A. Baker, Seyed A. Safavynia, Lisbeth A. Evered

doi : 10.1016/j.bja.2020.09.045

Volume 126, Issue 1, January 2021, Pages 44-47

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Prone positioning for patients intubated for severe acute respiratory distress syndrome (ARDS) secondary to COVID-19: a retrospective observational cohort study

Tyler T. Weiss, Flor Cerda, J. Brady Scott, Ramandeep Kaur, ... Jie Li

doi : 10.1016/j.bja.2020.09.042

Volume 126, Issue 1, January 2021, Pages 48-55

The role of repeated prone positioning in intubated subjects with acute respiratory distress syndrome caused by COVID-19 remains unclear.

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Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes

W. Scott Beattie, Manoj Lalu, Matthew Bocock, Simon Feng, ... Mark Johnson

doi : 10.1016/j.bja.2020.09.023

Volume 126, Issue 1, January 2021, Pages 56-66

Adverse cardiovascular events are a leading cause of perioperative morbidity and mortality. The definitions of perioperative cardiovascular adverse events are heterogeneous. As part of the international Standardized Endpoints in Perioperative Medicine initiative, this study aimed to find consensus amongst clinical trialists on a set of standardised and valid cardiovascular outcomes for use in future perioperative clinical trials.

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Cardiac output estimation using pulse wave analysis—physiology, algorithms, and technologies: a narrative review

Bernd Saugel, Karim Kouz, Thomas W.L. Scheeren, Gillis Greiwe, ... Daniel de Backer

doi : 10.1016/j.bja.2020.09.049

Volume 126, Issue 1, January 2021, Pages 67-76

Pulse wave analysis (PWA) allows estimation of cardiac output (CO) based on continuous analysis of the arterial blood pressure (AP) waveform. We describe the physiology of the AP waveform, basic principles of PWA algorithms for CO estimation, and PWA technologies available for clinical practice.

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A restrictive versus liberal transfusion strategy to prevent myocardial injury in patients undergoing surgery for fractured neck of femur: a feasibility randomised trial (RESULT-NOF)

Michael A. Gillies, Sadia Ghaffar, Iain K. Moppett, Annemarie B. Docherty, ... Timothy S. Walsh

doi : 10.1016/j.bja.2020.06.048

Volume 126, Issue 1, January 2021, Pages 77-86

The optimum transfusion strategy in patients with fractured neck of femur is uncertain, particularly if there is coexisting cardiovascular disease.

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Association between postoperative haemoglobin concentrations and composite of non-fatal myocardial infarction and all-cause mortality in noncardiac surgical patients: post hoc analysis of the POISE-2 trial

Alparslan Turan, Eva Rivas, Philip J. Devereaux, Mauro Bravo, ... Daniel I. Sessler

doi : 10.1016/j.bja.2020.08.054

Volume 126, Issue 1, January 2021, Pages 87-93

Myocardial infarction is the most common postoperative major vascular complication. Perioperative anaemia may contribute to cardiac supply–demand mismatch, and therefore myocardial injury. We therefore tested the hypothesis that the lowest in-hospital postoperative haemoglobin concentration is associated with a composite of non-fatal myocardial infarction and all-cause mortality within the first 30 days after noncardiac surgery.

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Association between postoperative haemoglobin and myocardial injury after noncardiac surgery: a retrospective cohort analysis

Alparslan Turan, Barak Cohen, Eva Rivas, Liu Liu, ... Daniel I. Sessler

doi : 10.1016/j.bja.2020.08.056

Volume 126, Issue 1, January 2021, Pages 94-101

Myocardial injury after noncardiac surgery (MINS) is common, mostly silent, and a strong predictor of postoperative mortality. MINS appears to result from myocardial supply–demand mismatch. Recent data support restrictive perioperative transfusion strategies that can result in low postoperative haemoglobin concentrations. Whether low postoperative haemoglobin is associated with myocardial injury remains unknown. We therefore tested the hypothesis that anaemia is associated with an increased risk of myocardial injury in adults having noncardiac surgery.

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Association between self-reported functional capacity and major adverse cardiac events in patients at elevated risk undergoing noncardiac surgery: a prospective diagnostic cohort study

Giovanna A.L. Lurati Buse, Christian Puelacher, Danielle Menosi Gualandro, Alessandro S. Genini, ... Daniel Rikli

doi : 10.1016/j.bja.2020.08.041

Volume 126, Issue 1, January 2021, Pages 102-110

Perioperative cardiovascular guidelines endorse functional capacity estimation, based on ‘cut-off’ daily activities for risk assessment and climbing two flights of stairs to approximate 4 metabolic equivalents. We assessed the association between self-reported functional capacity and postoperative cardiac events.

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New algorithm to quantify cardiopulmonary interaction in patients with atrial fibrillation: a proof-of-concept study

Piet A.H. Wyffels, Stefan De Hert, Patrick F. Wouters

doi : 10.1016/j.bja.2020.09.039

Volume 126, Issue 1, January 2021, Pages 111-119

Traditional formulas to calculate pulse pressure variation (PPV) cannot be used in patients with atrial fibrillation (AF). We have developed a new algorithm that accounts for arrhythmia-induced pulse pressure changes, allowing us to isolate and quantify ventilation-induced pulse pressure variation (VPPV). The robustness of the algorithm was tested in patients subjected to altered loading conditions. We investigated whether changes in VPPV imposed by passive leg raising (PLR) were proportional to the pre-PLR values.

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Consensus guidelines on perioperative management of malignant hyperthermia suspected or susceptible patients from the European Malignant Hyperthermia Group

Henrik Rüffert, B?rge Bastian, Diana Bendixen, Thierry Girard, ... D. ?t?p?nkov?

doi : 10.1016/j.bja.2020.09.029

Volume 126, Issue 1, January 2021, Pages 120-130

Malignant hyperthermia is a potentially fatal condition, in which genetically predisposed individuals develop a hypermetabolic reaction to potent inhalation anaesthetics or succinylcholine. Because of the rarity of malignant hyperthermia and ethical limitations, there is no evidence from interventional trials to inform the optimal perioperative management of patients known or suspected with malignant hyperthermia who present for surgery.

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Pharmacological interventions for the prevention of renal injury in surgical patients: a systematic literature review and meta-analysis

Suraj Pathak, Guido Olivieri, Walid Mohamed, Riccardo Abbasciano, ... Gavin J. Murphy

doi : 10.1016/j.bja.2020.06.064

Volume 126, Issue 1, January 2021, Pages 131-138

The aim of this systematic review was to summarise the results of randomised controlled trials (RCTs) that have evaluated pharmacological interventions for renoprotection in people undergoing surgery.

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Patient-maintained propofol sedation for adult patients undergoing surgical or medical procedures: a scoping review of current evidence and technology

David W. Hewson, Jonathan G. Hardman, Nigel M. Bedforth

doi : 10.1016/j.bja.2020.07.053

Volume 126, Issue 1, January 2021, Pages 139-148

Patient-maintained propofol sedation (PMPS) is the delivery of procedural propofol sedation by target-controlled infusion with the patient exerting an element of control over their target-site propofol concentration.

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Patient blood management interventions do not lead to important clinical benefits or cost-effectiveness for major surgery: a network meta-analysis

Marius A. Roman, Riccardo G. Abbasciano, Suraj Pathak, Shwe Oo, ... Gavin J. Murphy

doi : 10.1016/j.bja.2020.04.087

Volume 126, Issue 1, January 2021, Pages 149-156

Patient blood management (PBM) interventions aim to improve clinical outcomes by reducing bleeding and transfusion. We assessed whether existing evidence supports the routine use of combinations of these interventions during and after major surgery.

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The PREVENNT randomised, double-blind, controlled trial of preoperative intravenous iron to treat anaemia before major abdominal surgery: an independent discussion

Tom E.F. Abbott, Michael A. Gillies

doi : 10.1016/j.bja.2020.08.053

Volume 126, Issue 1, January 2021, Pages 157-162

Anaemia is a common finding in patients presenting for major elective surgery and is associated with poor outcomes including death and complications. Iron deficiency is the leading cause of perioperative anaemia.

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Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study establishing diagnostic criteria and prognostic importance

Pavel S. Roshanov, John W. Eikelboom, Daniel I. Sessler, Clive Kearon, ... Philip J. Devereaux

doi : 10.1016/j.bja.2020.06.051

Volume 126, Issue 1, January 2021, Pages 163-171

We aimed to establish diagnostic criteria for bleeding independently associated with mortality after noncardiac surgery (BIMS) defined as bleeding during or within 30 days after noncardiac surgery that is independently associated with mortality within 30 days of surgery, and to estimate the proportion of 30-day postoperative mortality potentially attributable to BIMS.

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Preoperative prediction of Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study

Pavel S. Roshanov, Gordon H. Guyatt, Vikas Tandon, Flavia K. Borges, ... Philip J. Devereaux

doi : 10.1016/j.bja.2020.02.028

Volume 126, Issue 1, January 2021, Pages 172-180

Diagnostic criteria for Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS) have been defined as bleeding that leads to a postoperative haemoglobin <70 g L?1, leads to blood transfusion, or is judged to be the direct cause of death. Preoperative prediction guides for BIMS can facilitate informed consent and planning of perioperative care.

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A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study

Bernhard Riedel, Michael H-G. Li, C.H. Angus Lee, Hilmy Ismail, ... H.C. Wijeysundera

doi : 10.1016/j.bja.2020.06.016

Volume 126, Issue 1, January 2021, Pages 181-190

Accurate assessment of functional capacity, a predictor of postoperative morbidity and mortality, is essential to improving surgical planning and outcomes. We assessed if all 12 items of the Duke Activity Status Index (DASI) were equally important in reflecting exercise capacity.

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Outcomes after endoscopic retrograde cholangiopancreatography with general anaesthesia versus sedation

Friederike C. Althoff, Abhishek Agnihotri, Stephanie D. Grabitz, Peter Santer, ... Matthias Eikermann

doi : 10.1016/j.bja.2020.08.057

Volume 126, Issue 1, January 2021, Pages 191-200

We tested the primary hypothesis that use of general anaesthesia vs sedation increases vulnerability to adverse discharge (in-hospital mortality or new discharge to a nursing facility) after endoscopic retrograde cholangiopancreatography (ERCP).

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Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trialPharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial

Stanislas Grassin-Delyle, Haleema Shakur-Still, Roberto Picetti, Lauren Frimley, ... Ian Roberts

doi : 10.1016/j.bja.2020.07.058

Volume 126, Issue 1, January 2021, Pages 201-209

Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth. It is most effective when given early. In many countries, pre-hospital care is provided by people who cannot give i.v. injections. We examined the pharmacokinetics of intramuscular TXA in bleeding trauma patients.

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Automated closed-loop versus manually controlled norepinephrine infusion in patients undergoing intermediate- to high-risk abdominal surgery: a randomised controlled trial

Alexandre Joosten, Dragos Chirnoaga, Philippe Van der Linden, Luc Barvais, ... Joseph Rinehart

doi : 10.1016/j.bja.2020.08.051

Volume 126, Issue 1, January 2021, Pages 210-218

Hypotension occurs frequently during surgery and may be associated with adverse complications. Vasopressor titration is frequently used to correct hypotension, but requires considerable time and attention, potentially reducing the time available for other clinical duties. To overcome this issue, we have developed a closed-loop vasopressor (CLV) controller to help correct hypotension more efficiently. The aim of this randomised controlled study was to evaluate whether the CLV controller was superior to traditional vasopressor management at minimising hypotension in patients undergoing abdominal surgery.

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Comparison of anaesthetic- and seizure-induced states of unconsciousness: a narrative review

Benjamin F. Gruenbaum

doi : 10.1016/j.bja.2020.07.056

Volume 126, Issue 1, January 2021, Pages 219-229

In order to understand general anaesthesia and certain seizures, a fundamental understanding of the neurobiology of unconsciousness is needed. This review article explores similarities in neuronal and network changes during general anaesthesia and seizure-induced unconsciousness. Both seizures and anaesthetics cause disruption in similar anatomical structures that presumably lead to impaired consciousness.

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Abnormal preoperative cognitive screening in aged surgical patients: a retrospective cohort analysis

Stephen H. Gregory, Christopher R. King, Arbi Ben Abdallah, Alex Kronzer, Troy S. Wildes

doi : 10.1016/j.bja.2020.08.026

Volume 126, Issue 1, January 2021, Pages 230-237

Preoperative cognitive dysfunction has been associated with adverse postoperative outcomes. There are limited data characterising the epidemiology of preoperative cognitive dysfunction in older surgical patients.

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Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo

Katarina Varn?s, Sjoerd J. Finnema, Peter Johnstr?m, Ryosuke Arakawa, ... Lars Farde

doi : 10.1016/j.bja.2020.08.052

Volume 126, Issue 1, January 2021, Pages 238-244

The molecular actions underlying the clinical effects of inhaled anaesthetics such as sevoflurane and isoflurane are not fully understood. Unexpected observations in positron emission tomography (PET) studies with [11C]AZD9272, a metabotropic glutamate receptor 5 (mGluR5) radioligand with possible affinity for monoamine oxidase-B (MAO-B), suggest that its binding is sensitive to anaesthesia with sevoflurane. The objective of the present study was to assess the effects of sevoflurane anaesthesia on the binding of [11C]AZD9272 and of [11C]L-deprenyl-D2, a radioligand selective for MAO-B in non-human primates (NHPs).

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The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3?,5?,17?)-3-hydroxyandrostane-17-carbonitrile

Tamara Timic Stamenic, Simon Feseha, Francesca M. Manzella, Damon Wallace, ... Slobodan M. Todorovic

doi : 10.1016/j.bja.2020.07.022

Volume 126, Issue 1, January 2021, Pages 245-255

The mechanisms underlying the role of T-type calcium channels (T-channels) in thalamocortical excitability and oscillations in vivo during neurosteroid-induced hypnosis are largely unknown.

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Efficacy of acute administration of inhaled argon on traumatic brain injury in mice

Federico Moro, Francesca Fossi, Aurora Magliocca, Rosaria Pascente, ... Elisa R. Zanier

doi : 10.1016/j.bja.2020.08.027

Volume 126, Issue 1, January 2021, Pages 256-264

Whilst there has been progress in supportive treatment for traumatic brain injury (TBI), specific neuroprotective interventions are lacking. Models of ischaemic heart and brain injury show the therapeutic potential of argon gas, but it is still not known whether inhaled argon (iAr) is protective in TBI. We tested the effects of acute administration of iAr on brain oedema, tissue micro-environmental changes, neurological functions, and structural outcome in a mouse model of TBI.

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Explaining anaesthetic hysteresis with effect-site equilibration

Alex Proekt, Max B. Kelz

doi : 10.1016/j.bja.2020.09.022

Volume 126, Issue 1, January 2021, Pages 265-278

Anaesthetic induction occurs at higher plasma drug concentrations than emergence in animal studies. Some studies find evidence for such anaesthetic hysteresis in humans, whereas others do not. Traditional thinking attributes hysteresis to drug equilibration between plasma and the effect site. Indeed, a key difference between human studies showing anaesthetic hysteresis and those that do not is in how effect-site equilibration was modelled. However, the effect-site is a theoretical compartment in which drug concentration cannot be measured experimentally. Thus, it is not clear whether drug equilibration models with experimentally intractable compartments are sufficiently constrained to unequivocally establish evidence for the presence or absence of anaesthetic hysteresis.

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Selective optogenetic activation of orexinergic terminals in the basal forebrain and locus coeruleus promotes emergence from isoflurane anaesthesia in rats

Dan Wang, Yongxin Guo, Huiming Li, Jiannan Li, ... Hailong Dong

doi : 10.1016/j.bja.2020.09.037

Volume 126, Issue 1, January 2021, Pages 279-292

The neuropeptide orexin promotes arousal from general anaesthesia, however the neuronal circuits that mediate this effect have not been defined. We investigated whether orexinergic neurones modulate the basal forebrain (BF) and locus coeruleus (LC) in emergence from anaesthesia.

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Frontal electroencephalogram activity during emergence from general anaesthesia in children with and without emergence delirium

Jonghae Kim, Hyung-Chul Lee, Sung-Hye Byun, Hyunyoung Lim, ... Eugene Kim

doi : 10.1016/j.bja.2020.07.060

Volume 126, Issue 1, January 2021, Pages 293-303

Emergence delirium (ED) in children after general anaesthesia causes significant distress in patients, their family members, and clinicians; however, electroencephalogram (EEG) markers predicting ED have not been fully investigated.

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Perioperative Pain and Addiction Interdisciplinary Network (PAIN): consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users by a modified Delphi process

Karim S. Ladha, Alexander McLaren-Blades, Akash Goel, Michael J. Buys, ... Hance Clarke

doi : 10.1016/j.bja.2020.09.026

Volume 126, Issue 1, January 2021, Pages 304-318

In many countries, liberalisation of the legislation regulating the use of cannabis has outpaced rigorous scientific studies, and a growing number of patients presenting for surgery consume cannabis regularly. Research to date suggests that cannabis can impact perioperative outcomes. We present recommendations obtained using a modified Delphi method for the perioperative care of cannabis-using patients.

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Association of weaning failure from mechanical ventilation with transthoracic echocardiography parameters: a systematic review and meta-analysis

Filippo Sanfilippo, Davide Di Falco, Alberto Noto, Cristina Santonocito, ... Marinella Astuto

doi : 10.1016/j.bja.2020.07.059

Volume 126, Issue 1, January 2021, Pages 319-330

Weaning from mechanical ventilation is a challenging step during recovery from critical illness. Weaning failure or early reintubation are associated with increased morbidity and mortality, exposing patients to life-threatening complications. Cardiac dysfunction represents the most common cause of weaning failure. We conducted a systematic review and meta-analysis to evaluate the association between transthoracic echocardiographic parameters and weaning failure.

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A comparison of videolaryngoscopy using standard blades or non-standard blades in children in the Paediatric Difficult Intubation Registry

James Peyton, Raymond Park, Steven J. Staffa, Stefano Sabato, ... Rob Greenberg

doi : 10.1016/j.bja.2020.08.010

Volume 126, Issue 1, January 2021, Pages 331-339

The design of a videolaryngoscope blade may affect its efficacy. We classified videolaryngoscope blades as standard and non-standard shapes to compare their efficacy performing tracheal intubation in children enrolled in the Paediatric Difficult Intubation Registry.

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Network meta-analysis of isolated patient blood management interventions leads to uncertain interpretation. Comment on Br J Anaesth 2020; https://doi.org/10.1016/j.bja.2020.04.087

David Faraoni, Irvin Gross, Aryeh Shander

doi : 10.1016/j.bja.2020.07.021

Volume 126, Issue 1, January 2021, Pages e1-e2

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Interpretation of network meta-analysis of isolated patient blood management interventions. Response to Br J Anaesth 2020 BJA-2020-01426-HH887.R1

Marius A. Roman, Riccardo G. Abbasciano, Florence Y. Lai, Gavin J. Murphy

doi : 10.1016/j.bja.2020.08.039

Volume 126, Issue 1, January 2021, Pages e2-e4

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Patient blood management interventions lead to important benefits for major surgery. Comment on Br J Anaesth 2020

Mazyar Javidroozi, Jean-Francois Hardy, Sherri Ozawa

doi : 10.1016/j.bja.2020.10.009

Volume 126, Issue 1, January 2021, Pages e4-e5

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Is patient blood management cost-effective? Response to Br J Anaesth 2020 https://doi.org/10.1016/j.bja.2020.09.003

Marius A. Roman, Riccardo G. Abbasciano, Guiqing Yao, Gavin J. Murphy

doi : 10.1016/j.bja.2020.08.029

Volume 126, Issue 1, January 2021, Pages e6-e7

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Is patient blood management cost-effective? Comment on Br J Anaesth 2020

Kevin M. Trentino, Donat R. Spahn, Hamish S. Mace, Hans Gombotz, Axel Hofmann

doi : 10.1016/j.bja.2020.09.003

Volume 126, Issue 1, January 2021, Pages e7-e9

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Comparison between ultrasound-guided and digital palpation techniques for identification of the cricothyroid membrane: a meta-analysis

Kuo-Chuan Hung, I-Wen Chen, Chien-Ming Lin, Cheuk-Kwan Sun

doi : 10.1016/j.bja.2020.08.012

Volume 126, Issue 1, January 2021, Pages e9-e11

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Entrainment of brain network oscillations in anaesthesia. Comment on Br J Anaesth 2020; 125: 330–335

Friedrich Lersch, Darren Hight, Flavio Frohlich

doi : 10.1016/j.bja.2020.08.028

Volume 126, Issue 1, January 2021, Pages e11-e12

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Brainwave entrainment to minimise sedative drug doses in paediatric surgery. Response to Br J Anaesth 2020

Werner Schmid, Peter Marhofer, Wolfgang Klug

doi : 10.1016/j.bja.2020.09.034

Volume 126, Issue 1, January 2021, Page e13

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Counting the train-of-four twitch response: comparison of palpation with mechanomyography, acceleromyography, and electromyography. Comment on Br J Anaesth 2020; 124: 712–7

Thomas Fuchs-Buder

doi : 10.1016/j.bja.2020.09.016

Volume 126, Issue 1, January 2021, Pages e14-e15

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Visualising the pressure-time burden of elevated intracranial pressure after severe traumatic brain injury: a retrospective confirmatory study

Joseph Donnelly, Fabian Güiza, Bart Depreitere, Geert Meyfroidt, ... Peter Smielewski

doi : 10.1016/j.bja.2020.09.018

Volume 126, Issue 1, January 2021, Pages e15-e17

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Overfatigue amongst Chinese anaesthesiologists from 2017 to 2019

Ying-J. Du, Xin-Q. Zhang, Li-D. Liu, Jin-Y. Zhang, ... Gu-Y. Wang

doi : 10.1016/j.bja.2020.09.032

Volume 126, Issue 1, January 2021, Pages e17-e19

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State of the anaesthesia workforce in the United States: trends and geographic variation in nurse anaesthetist to physician anaesthesiologist ratios

Lauren A. Wilson, Jashvant Poeran, Jiabin Liu, Haoyan Zhong, Stavros G. Memtsoudis

doi : 10.1016/j.bja.2020.10.001

Volume 126, Issue 1, January 2021, Pages e19-e21

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Self-citation policies in anaesthesiology journals

Filippo Sanfilippo, Stefano Tigano, Alberto Morgana, Paolo Murabitol, Marinella Astuto

doi : 10.1016/j.bja.2020.10.002

Volume 126, Issue 1, January 2021, Pages e21-e25

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Use of sphenopalatine ganglion block in patients with postdural puncture headache: a pilot meta-analysis

Kuo-Chuan Hung, Jen-Yin Chen, Chun-Ning Ho, Cheuk-Kwan Sun

doi : 10.1016/j.bja.2020.10.005

Volume 126, Issue 1, January 2021, Pages e25-e27

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Immunoglobulin E cross-linking or MRGPRX2 activation: clinical insights from rocuronium hypersensitivity

Didier G. Ebo, Marie-Line Van der Poorten, Jessy Elst, Athina L. Van Gasse, ... Vito Sabato

doi : 10.1016/j.bja.2020.10.006

Volume 126, Issue 1, January 2021, Pages e27-e29

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Factors affecting need for manipulation after total knee arthroplasty: a retrospective case–control cohort study

Steven B. Porter, Haoyan Zhong, Christopher B. Robards, Jiabin Liu, ... Stavros Memtsoudis

doi : 10.1016/j.bja.2020.10.007

Volume 126, Issue 1, January 2021, Pages e29-e31

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Normalising renal tissue oxygen tension with higher inspired oxygen concentration may be falsely reassuring. Comment on Br J Anaesth 2020;125:192–200

Ari Ercole

doi : 10.1016/j.bja.2020.10.017

Volume 126, Issue 1, January 2021, Page e32

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Potential therapeutic value of dexmedetomidine in COVID-19 patients admitted to ICU

Hailin Zhao, Roger Davies, Daqing Ma

doi : 10.1016/j.bja.2020.09.031

Volume 126, Issue 1, January 2021, Pages e33-e35

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Dexmedetomidine: another arrow in the quiver to fight COVID-19 in intensive care units

Amit Jain, Massimo Lamperti, D. John Doyle

doi : 10.1016/j.bja.2020.10.010

Volume 126, Issue 1, January 2021, Pages e35-e38

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High fresh gas flow during non-inhalational anaesthesia during the COVID-19 pandemic. Comment on Br J Anaesth 2020; 125: 773-778

Alexander Hall, Abhijoy Chakladar

doi : 10.1016/j.bja.2020.09.033

Volume 126, Issue 1, January 2021, Pages e38-e39

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Psychological impact of COVID-19 on staff working in paediatric and adult critical care

Robert ffrench-O'Carroll, Tara Feeley, Mong Hoi Tan, Claire Magner, ... Shauna Delaney

doi : 10.1016/j.bja.2020.09.040

Volume 126, Issue 1, January 2021, Pages e39-e41

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Trials in pandemics: here we go again?

Steve Harris, Ed Palmer, Kevin Fong

doi : 10.1016/j.bja.2020.10.008

Volume 126, Issue 1, January 2021, Pages e42-e44

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Inhaled nitric oxide minimally improves oxygenation in COVID-19 related acute respiratory distress syndrome

Alessia Longobardo, Cecilia Montanari, Robert Shulman, Suzanne Benhalim, ... Nishkantha Arulkumaran

doi : 10.1016/j.bja.2020.10.011

Volume 126, Issue 1, January 2021, Pages e44-e46

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Response of US hospitals to elective surgical cases in the COVID-19 pandemic

Romain Pirracchio, Orestes Mavrothalassitis, Michael Mathis, Sachin Kheterpal, Matthieu Legrand

doi : 10.1016/j.bja.2020.10.013

Volume 126, Issue 1, January 2021, Pages e46-e48

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Respiratory personal protective equipment for healthcare workers: impact of sex differences on respirator fit test results

Anna Ascott, Paul Crowest, Eleanor de Sausmarez, Mansoor Khan, Abhijoy Chakladar

doi : 10.1016/j.bja.2020.10.016

Volume 126, Issue 1, January 2021, Pages e48-e49

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Influence of room ventilation settings on aerosol clearance and distribution

Nicolaas H. Sperna Weiland, Roberto A.A.L. Traversari, Jante S. Sinnige, Frank van Someren Gréve, ... Markus W. Hollmann

doi : 10.1016/j.bja.2020.10.018

Volume 126, Issue 1, January 2021, Pages e49-e52

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Corrigendum to ‘Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial’ (Br J Anaesth 2017; 118: 720–32)

Gertrude J. Nieuwenhuijs-Moeke, Vincent B. Nieuwenhuijs, Marc A.J. Seelen, Stefan P. Berger, ... Michel M.R.F. Struys

doi : 10.1016/j.bja.2020.10.024

Volume 126, Issue 1, January 2021, Pages 340-341

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