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ARE THERE TWO FORMS OF MULTIPLE EVANESCENT WHITE DOT SYNDROME?
Essilfie, Juliet MD*,†,‡; Bacci, Tommaso MD*,†; Abdelhakim, Aliaa H. MD, PhD*,†,‡,§; Ramtohul, Prithvi MD¶,**; Turchi, Federica MD††; Freund, K. Bailey MD*,†,§,‡‡; Yannuzzi, Lawrence A. MD*,†,§,‡‡
doi : 10.1097/IAE.0000000000003288
February 2022 - Volume 42 - Issue 2 - p 227-235
To analyze the nature of multiple evanescent white dot syndrome (MEWDS) and differentiate an idiopathic or primary form of MEWDS from a secondary form that is seen in association with other clinical conditions affecting the posterior segment of the eye.
LOW VULNERABILITY OF THE POSTERIOR EYE SEGMENT TO SARS-COV-2 INFECTION
Künzel, Steffen Emil MD*; Bürgel, Thore MSc†; Künzel, Sandrine Helene MD‡; Pohlmann, Dominika MD*; Zeitz, Oliver MD*; Joussen, Antonia MD*; Dubrac, Alexandre PhD§,¶
doi : 10.1097/IAE.0000000000003320
February 2022 - Volume 42 - Issue 2 - p 236-243
Retinal manifestations have been described in COVID-19 patients, but it is unknown whether SARS-CoV-2, the causal agent in COVID-19, can directly infect posterior ocular tissues. Here, we investigate SARS-CoV-2 host factor gene expression levels and their distribution across retinal and choroidal cell types.
LONG-TERM VISUAL OUTCOMES AND THE TIMING OF SURGICAL REPAIR OF FOVEA-SPLITTING RHEGMATOGENOUS RETINAL DETACHMENTS
Lee, Ramon MD*; Shields, Ryan A. MD*; Maywood, Michael J. BS†; Nemeth, Cire BS‡; Wa, Christianne A. MD*; Williams, George A. MD*,†; Hassan, Tarek S. MD*,†; Garretson, Bruce R. MD*,†; Capone, Antonio Jr MD*,†; Ruby, Alan J. MD*,†; Drenser, Kimberly A. MD, PhD*,†; Faia, Lisa J. MD*,†; Randhawa, Sandeep MD*,†; Mahmoud, Tamer H. MD, PhD*,†; Wolfe, Jeremy D. MD, MS*,†
doi : 10.1097/IAE.0000000000003293
February 2022 - Volume 42 - Issue 2 - p 244-249
To evaluate the visual outcomes and the affect of timing of surgical repair of fovea-splitting rhegmatogenous retinal detachments.
THE PROPHYLAXIS OF FELLOW-EYE RETINAL DETACHMENT IN STICKLER SYNDROME
Ripandelli, Guido MD*; Rossi, Tommaso MD†; Pesci, Francesca R. PhD*; Cecere, Michela MD*; Stirpe, Mario MD*
doi : 10.1097/IAE.0000000000003304
February 2022 - Volume 42 - Issue 2 - p 250-255
To evaluate retrospectively if scleral buckling combined or not to cryopexy reduces fellow-eye retinal detachment (RD) in Stickler syndrome patients who lost their first eye due to RD.
PREVALENCE AND RISK FACTORS OF ELLIPSOID ZONE DAMAGE AFTER PARS PLANA VITRECTOMY FOR IDIOPATHIC EPIRETINAL MEMBRANE
Post, Micha? MD, PhD*,†; Cicinelli, Maria Vittoria MD‡,§; Zanzottera, Emma Clara MD*; Marchese, Alessandro MD*,‡,§; Bandello, Francesco MD‡,§; Coppola, Michele MD*
doi : 10.1097/IAE.0000000000003321
February 2022 - Volume 42 - Issue 2 - p 256-264
To assess factors associated with external limiting membrane (ELM)/ellipsoid zone (EZ) damage after pars plana vitrectomy (PPV) for epiretinal membrane and evaluate ELM/EZ damage impact on functional and anatomical outcomes.
LONGITUDINAL ELLIPSOID ZONE AND OUTER RETINAL INTEGRITY DYNAMICS AFTER EPIRETINAL MEMBRANE SURGERY
Tuifua, Tisileli S. BSc*,†; Abraham, Joseph R. MD*; Srivastava, Sunil K. MD*,‡; Kaiser, Peter K. MD‡; Reese, Jamie BSN*; Ehlers, Justis P. MD*,‡
doi : 10.1097/IAE.0000000000003306
February 2022 - Volume 42 - Issue 2 - p 265-273
To quantify ellipsoid zone (EZ) changes in integrity after epiretinal membrane (ERM) surgery, correlate findings to visual acuity, and determine predictors for prognosis.
THE SPECTRUM OF INTERNAL LIMITING MEMBRANE DISEASE IN ALPORT SYNDROME
Cicinelli, Maria Vittoria MD*,†,‡; Ritter, Markus MD§; Ghossein, Cybele MD¶; Aschauer, Constantin MD**; Laccone, Franco MD††; Nagel, Mato MD‡‡; Schmidt-Erfurth, Ursula M. MD§; Jampol, Lee M. MD*; Gill, Manjot K. MD*
doi : 10.1097/IAE.0000000000003295
February 2022 - Volume 42 - Issue 2 - p 274-282
To characterize the spectrum of internal limiting membrane (ILM) disease in Alport syndrome using multimodal imaging, including widefield (WF) and ultra-widefield (UWF) modalities, and to report their relative prevalence according to the genetic pattern of inheritance.
ALTMETRIC ANALYSIS OF THE MOST-CITED 100 ARTICLES ON THE RETINA PUBLISHED BETWEEN 2010 AND 2020
Sener, Hidayet MD*; Polat, Osman Ahmet MD†
doi : 10.1097/IAE.0000000000003318
February 2022 - Volume 42 - Issue 2 - p 283-289
Altmetric analysis is a way of assessing the social impact of scientific articles. In this study, we aimed to analyze the 100 most-cited articles on the topic of the retina published in ophthalmology journals in traditional metrics and altmetrics.
EFFICACY AND SAFETY OF AFLIBERCEPT FOR THE TREATMENT OF IDIOPATHIC CHOROIDAL NEOVASCULARIZATION IN YOUNG PATIENTS
Kodjikian, Laurent MD, PhD*,†,‡; Tadayoni, Ramin MD, PhD§,¶; Souied, Eric H. MD, PhD**; Baillif, Stéphanie MD, PhD††; Milazzo, Solange MD, PhD‡‡; Dumas, Stéphane MD§§; Uzzan, Joël MD¶¶; Bernard, Lorraine MSc†,***,†††; Decullier, Evelyne PhD‡‡‡; Huot, Laure PharmD, PhD‡‡‡; Mathis, Thibaud MD, PhD*,†,‡
doi : 10.1097/IAE.0000000000003310
February 2022 - Volume 42 - Issue 2 - p 290-297
To evaluate the mean change in visual acuity at 52 weeks in patients with idiopathic choroidal neovascularization treated with aflibercept.
EN-FACE IMAGING OF ATYPICAL EPIRETINAL TISSUE IN LAMELLAR MACULAR HOLE
Eun, Jun Soo MD*,†; Choi, Young Joo MD*; Kang, Se Woong MD, PhD*; Choi, Kyung Jun MD*; Kim, Sang Jin MD, PhD*; Roh, Hyeon Cheol MD*,‡
doi : 10.1097/IAE.0000000000003303
February 2022 - Volume 42 - Issue 2 - p 298-305
To elucidate the significance of en-face optical coherence tomography imaging of atypical epiretinal tissue (AET) in the lamellar macular hole (LMH).
LENS CAPSULAR FLAP TRANSPLANTATION AS PRIMARY TREATMENT FOR CLOSURE OF LARGE MACULAR HOLES
Peng, Jie MD*; Chen, Chunli MD†; Zhang, Lihua MD‡; Huang, Yue MD§; Zhang, Hongtao MD‡; Zheng, Yan MD*,§; Ren, Jianing MD*; Zou, Yihua MD*; Zhang, Xuerui MD*; Zhao, Peiquan MD*
doi : 10.1097/IAE.0000000000003315
February 2022 - Volume 42 - Issue 2 - p 306-312
To report the long-term outcomes of lens capsular flap transplantation (LCFT) as initial treatment for large macular holes (MHs).
RESTORATION PROCESS OF THE OUTER RETINAL LAYERS AFTER SURGICAL MACULAR HOLE CLOSURE
Iwasaki, Masanori MD*; Ando, Ryo MD, PhD†; Aoki, Shuichiro MD*; Miyamoto, Hirotomo MD*
doi : 10.1097/IAE.0000000000003323
February 2022 - Volume 42 - Issue 2 - p 313-320
To investigate the interrelationship among the outer retinal layers after macular hole surgery and elucidate the restoration process.
CLINICAL CHARACTERISTICS AND VISUAL OUTCOMES IN ENDOPHTHALMITIS AFTER KERATOPROSTHESIS IMPLANTATION
Lee, Terry BA*; Robbins, Cason B. BS*; Wisely, Clayton E. MD, MBA†; Grewal, Dilraj S. MD†; Daluvoy, Melissa B. MD†; Fekrat, Sharon MD†
doi : 10.1097/IAE.0000000000003300
February 2022 - Volume 42 - Issue 2 - p 321-327
To describe the presentation, microbiology, management, and prognosis of eyes with endophthalmitis after Boston keratoprosthesis implantation.
NEW METHOD FOR REDUCING ARTIFACTUAL FLOW DEFICITS CAUSED BY COMPENSATION TECHNIQUES IN THE CHORIOCAPILLARIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
Nesper, Peter L. MS; Fawzi, Amani A. MD
doi : 10.1097/IAE.0000000000003313
February 2022 - Volume 42 - Issue 2 - p 328-335
To mitigate artifactual choriocapillaris flow deficits in optical coherence tomography angiography, which are a side effect of inverse structural optical coherence tomography compensation.
STARDUST SIGN AND RETINAL TEAR DETECTION ON SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY
Itakura, Hirotaka MD*; Itakura, Mariko MD*; Sato, Taku MD†
doi : 10.1097/IAE.0000000000003317
February 2022 - Volume 42 - Issue 2 - p 336-339
The causes of floaters include posterior vitreous detachment and fundus hemorrhage, both of which are risk factors for retinal tears. We observed the vitreous of patients with floaters using swept source optical coherence tomography.
EVALUATION OF MACULAR FLOW VOIDS ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AS POTENTIAL BIOMARKERS FOR SILENT CEREBRAL INFARCTION IN SICKLE CELL DISEASE
Thangamathesvaran, Loka MD*; Ong, Sally S. MD†; Wang, Jiangxia MS‡; Lance, Eboni MD, PhD§; Tekes, Aylin MD¶; Scott, Adrienne W. MD*
doi : 10.1097/IAE.0000000000003309
February 2022 - Volume 42 - Issue 2 - p 340-347
To determine the relationship between macular microvascular abnormalities on optical coherence tomography angiography and silent cerebral infarctions (SCIs) on cerebral magnetic resonance imaging in sickle cell disease.
CORRELATION BETWEEN FOCAL CHOROIDAL EXCAVATION AND UNDERLYING RETINOCHOROIDAL DISEASE
Gan, Yuhong MD; Ji, Yuying MD, PhD; Zuo, Chengguo MD, PhD; Su, Yongyue MD; Liao, Nanying MD; Zhang, Xiongze MD, PhD; Zeng, Yunkao MD; Wen, Feng MD, PhD
doi : 10.1097/IAE.0000000000003307
February 2022 - Volume 42 - Issue 2 - p 348-356
To evaluate focal choroidal excavation (FCE) in eyes with various diseases using multimodal imaging modalities and to investigate the correlation of FCE and underlying chorioretinal diseases.
MULTISCALE CORRELATION OF MICROVASCULAR CHANGES ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY WITH RETINAL SENSITIVITY IN DIABETIC RETINOPATHY
Levine, Emily S. MD, MTM*,†; Moult, Eric M. BSc‡; Greig, Eugenia Custo MD*,§; Zhao, Yi MSc¶; Pramil, Varsha MS*; Gendelman, Isaac MD*; Alibhai, Agha Y. MD*; Baumal, Caroline R. MD*; Witkin, Andre J. MD*; Duker, Jay S. MD*; Fujimoto, James G. PhD‡; Waheed, Nadia K. MD, MPH*
doi : 10.1097/IAE.0000000000003299
February 2022 - Volume 42 - Issue 2 - p 357-368
To assess global, zonal, and local correlations between vessel density changes measured by optical coherence tomography angiography and retinal sensitivity measured by microperimetry across diabetic retinopathy severity.
SMOKING, RURAL RESIDENCE AND DIABETES AS RISK FACTORS FOR PRESUMED OCULAR HISTOPLASMOSIS SYNDROME
Richey, Brad F. BIS*; Obrock, Rachel S. OD†; Gee, Zachary M. BS, MS‡; Lu, David Y. MD§; Jacobsen, Gordon MS¶; Richards, Scott C. MD†
doi : 10.1097/IAE.0000000000003322
February 2022 - Volume 42 - Issue 2 - p 369-374
To investigate the relationship of smoking, urbanicity, and diabetes to presumed ocular histoplasmosis syndrome (POHS) and associated choroidal neovascularization (CNV).
CENTRAL SEROUS CHORIORETINOPATHY
Gerardy, Melvin MD*; Yesilirmak, Nilufer MD*; Legras, Richard PhD†; Behar-Cohen, Francine MD, PhD*,‡; Bousquet, Elodie MD, PhD*,‡
doi : 10.1097/IAE.0000000000003311
February 2022 - Volume 42 - Issue 2 - p 375-380
To investigate cone density in the asymptomatic fellow eye of patients with unilateral central serous chorioretinopathy (CSCR).
CHOROIDAL VASCULARITY INDEX IS ASSOCIATED WITH GEOGRAPHIC ATROPHY PROGRESSION
Sacconi, Riccardo MD, FEBO*,†; Battista, Marco MD*,†; Borrelli, Enrico MD, FEBO*,†; Senni, Carlotta MD*,†; Tombolini, Beatrice MD*,†; Grosso, Domenico MD*,†; Querques, Lea MD†; Bandello, Francesco MD, FEBO*,†; Querques, Giuseppe MD, PhD*,†
doi : 10.1097/IAE.0000000000003305
February 2022 - Volume 42 - Issue 2 - p 381-387
To investigate the correlation between choroidal vascularity index and the enlargement of geographic atrophy (GA) lesion secondary to age-related macular degeneration during the 2-year follow-up.
HYPERREFLECTIVE FOCI AS IMPORTANT PROGNOSTIC INDICATORS OF PROGRESSION OF RETINITIS PIGMENTOSA
Huang, Chu-Hsuan MD*; Yang, Chang-Hao MD, PhD†,‡; Lai, Ying-Ju MS§; Hsiao, Chuhsing Kate PhD§; Hou, Yu-Chih MD*; Yang, Chung-May MD, PhD†,‡; Chen, Ta-Ching MD, PhD†,‡
doi : 10.1097/IAE.0000000000003301
February 2022 - Volume 42 - Issue 2 - p 388-395
To investigate the presence and clinical relevance of hyperreflective foci (HRFs) in retinitis pigmentosa.
OCULAR MANIFESTATIONS OF ASP38ALA AND THR59LYS FAMILIAL TRANSTHYRETIN AMYLOIDOSIS
Choi, Kyung Jun MD*; Son, Ki Young MD*; Kang, Se Woong MD, PhD*; Kim, Darae MD, PhD†; Choi, Jin Oh MD, PhD†; Kim, Hee Jin MD, PhD‡; Kim, Jung Sun MD, PhD§; Jeon, Eun Seok MD, PhD†; Kim, A Young MD¶; Kang, Min Chae MD*; Kim, Sang Jin MD, PhD*
doi : 10.1097/IAE.0000000000003296
February 2022 - Volume 42 - Issue 2 - p 396-403
To describe the ophthalmic manifestations of familial transthyretin amyloidosis (FTA) mutations, including Asp38Ala and Thr59Lys, which have not been previously reported to have ocular involvement.
Diagnostic and Therapeutic Challenges
Peng, Wen-Yan Drs.; Zhou, Shi-You; Ma, Jin; Gross, Jeffrey G.
doi : 10.1097/IAE.0000000000003144
February 2022 - Volume 42 - Issue 2 - p 404-409
Diagnostic and Therapeutic Challenges
Ramtohul, Prithvi Drs.; Comet, Alban; Denis, Danièle; Jumper, J. Michael
doi : 10.1097/IAE.0000000000003150
February 2022 - Volume 42 - Issue 2 - p 410-412
