Clinical and Translational Gastroenterology




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Gastric Cancer in Alaska Native and American Indian People Living in Alaska, 1990–2017

Nolen, Leisha D. MD, PhD1; Bressler, Sara MSPH1; Vindigni, Stephen M. MD, MPH2,3; Miller, Keri MHA2; Nash, Sarah PhD, MPH2

doi : 10.14309/ctg.0000000000000374

July 2021 - Volume 12 - Issue 7 - p e00374

Alaska Native (AN) people experience a high burden of gastric cancer compared with other US Native and non-Native populations. Previous reports have suggested that gastric cancer in AN people occurs at a younger age and is a more aggressive pathologic type. We evaluated all cases of gastric cancer in AN people from 1990 to 2017 and compared the epidemiologic and pathologic characteristics with the gastric cancers that occurred in the same time in the US white (USW) population.

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A Potential Oncogenic Role for PFKFB3 Overexpression in Gastric Cancer Progression

Lei, Lan MD1; Hong, Lian-Lian PhD1; Ling, Zhe-Nan MD2; Zhong, Yi MD Candidate3; Hu, Xuan-Yu MD1,4; Li, Pei MD, PhD4; Ling, Zhi-Qiang MD, PhD1

doi : 10.14309/ctg.0000000000000377

July 2021 - Volume 12 - Issue 7 - p e00377

PFKFB3 regulates glycolysis in tumor cells, might function as an oncogene, and is associated with cancer metastasis. However, its role in gastric cancer (GC) remains largely unknown.

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Safety of Endoscopy in Peritoneal Dialysis Patients

Kim, Joon Sung MD, PhD1; Jung, Eunha MD2; Kang, Sun Hyung MD, PhD3; Ji, Jeong-Seon MD, PhD1; Cho, Yu Kyung MD, PhD2; Lee, Bo-In MD, PhD2; Cho, Young-Seok MD, PhD2; Kim, Byung-Wook MD, PhD1; Choi, Hwang MD, PhD1; Jeong, Hyun Yong MD, PhD3; Choi, Myung-Gyu MD, PhD2; Park, Jae Myung MD, PhD2

doi : 10.14309/ctg.0000000000000379

July 2021 - Volume 12 - Issue 7 - p e00379

Endoscopic procedures can provoke peritonitis in patients receiving peritoneal dialysis (PD). The aim of this study was to assess the development of peritonitis after endoscopic procedures in PD patients.

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Obesity Is Not Associated With an Increased Risk of Serious Infections in Biologic-Treated Patients With Inflammatory Bowel Diseases

Singh, Siddharth MD, MS1,2; Heien, Herbert C. MS3; Sangaralingham, Lindsey MPH3; Shah, Nilay D. PhD3,4; Sandborn, William J. MD1

doi : 10.14309/ctg.0000000000000380

July 2021 - Volume 12 - Issue 7 - p e00380

Obesity has been associated with adverse disease-related outcomes and inferior treatment response to biologic agents in patients with inflammatory bowel diseases (IBDs), but its impact on the risk of treatment-related complications is unknown. We performed a cohort study examining the association between obesity and risk of serious infections in biologic-treated patients with IBD.

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Sensory Adaptation Training or Escitalopram for IBS With Constipation and Rectal Hypersensitivity: A Randomized Controlled Trial

Rao, Satish S.C. MD, PhD, FRCP1,2; Coss-Adame, Enrique MD1,2; Yan, Yun MD, PhD1; Erdogan, Askin MD1; Valestin, Jessica BSc2; Ayyala, Deepak Nag PhD3

doi : 10.14309/ctg.0000000000000381

July 2021 - Volume 12 - Issue 7 - p e00381

Rectal hypersensitivity is an important pathophysiological dysfunction in irritable bowel syndrome with predominant constipation (IBS-C), whose treatment remains challenging. In a randomized controlled trial, we compared the efficacy and safety of a novel sensori-behavioral treatment, sensory adaptation training (SAT) with escitalopram.

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Comment on “Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis”

Weng, Fangbin MD1

doi : 10.14309/ctg.0000000000000382

July 2021 - Volume 12 - Issue 7 - p e00382

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Response to Weng

Allegretti, Andrew S. MD, MSc1, on behalf of the HRS-HARMONY study investigators

doi : 10.14309/ctg.0000000000000383

July 2021 - Volume 12 - Issue 7 - p e00383

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Correction to: Positive Fecal Immunochemical Test Strongly Predicts Adenomas in Younger Adults With Fatty Liver and Metabolic Syndrome

Yeh, Jen-Hao MD1,2,3; Lin, Chih-Wen MD, PhD1,3,4; Wang, Wen-Lun MD, PhD3,4; Lee, Ching-Tai MD3,4; Chen, Jen-Chieh MD1,5; Hsu, Chia-Chang MD3,5; Wang, Jaw-Yuan MD, PhD6,7,8,9

doi : 10.14309/ctg.0000000000000368

July 2021 - Volume 12 - Issue 7 - p e00368

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