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Evaluating perinatal outcomes during a pandemic: A role for living systematic reviews
Rohan D’Souza,Isabelle Malhamé,Prakesh S. Shah
doi : 10.1111/aogs.14305
Volume 101, Issue 1 p. 4-6
Coronavirus disease 2019 pandemic and pregnancy and neonatal outcomes in general population: A living systematic review and meta-analysis (updated Aug 14, 2021)
Jie Yang,Rohan D’Souza,Ashraf Kharrat,Deshayne B. Fell,John W. Snelgrove,Kellie E. Murphy,Prakesh S. Shah
doi : 10.1111/aogs.14277
Volume 101, Issue 1 p. 7-24
Conflicting reports of increases and decreases in rates of preterm birth (PTB) and stillbirth in the general population during the coronavirus disease 2019 (COVID-19) pandemic have surfaced. The objective of our study was to conduct a living systematic review and meta-analyses of studies reporting pregnancy and neonatal outcomes by comparing the pandemic and pre-pandemic periods.
The effects of obstetric emergency team training on patient outcome: A systematic review and meta-analysis
Lise Brogaard,Kasper Glerup Lauridsen,Bo Løfgren,Kristian Krogh,Charlotte Paltved,Sidsel Boie,Lone Hvidman
doi : 10.1111/aogs.14263
Volume 101, Issue 1 p. 25-36
Little is known about the optimal simulation-based team training in obstetric emergencies. We aimed to review how simulation-based team training affects patient outcomes in obstetric emergencies.
Histopathological examination of the ectocervical biopsy in non-transplanted uteri: A study contributing to the provisional scoring system of subclinical graft rejection after uterus transplantation
Jan Balko,Marta Novackova,Petr Skapa,Zlatko Pastor,Roman Chmel Jr.,Josef Zamecnik,Roman Chmel
doi : 10.1111/aogs.14280
Volume 101, Issue 1 p. 37-45
Uterus transplantation is a causal treatment for absolute uterine factor infertility. Assessing rejection signs using a histopathological examination of the ectocervical biopsy from the transplanted uterus is common practice in all human uterus transplants worldwide to date. A provisional scoring system was used for the histopathological assessment of subclinical rejection signs in uterus recipients. Here we hypothesized that histopathological and immunohistochemical findings in the normal uteri would differ from the borderline category of subclinical rejection in uterine transplants.
Evaluating cut-off levels for progesterone, ? human chorionic gonadotropin and ? human chorionic gonadotropin ratio to exclude pregnancy viability in women with a pregnancy of unknown location: A prospective multicenter cohort study
Shabnam Bobdiwala,Christopher Kyriacou,Evangelia Christodoulou,Jessica Farren,Nicola Mitchell-Jones,Maya Al-Memar,Francis Ayim,Baljinder Chohan,Emma Kirk,Osama Abughazza,Bramara Guruwadahyarhalli,Sharmistha Guha,Veluppillai Vathanan,Debbie Gould,Catriona Stalder,Dirk Timmerman,Ben Van Calster,Tom Bourne
doi : 10.1111/aogs.14295
Volume 101, Issue 1 p. 46-55
There is no global agreement on how to best determine pregnancy of unknown location viability and location using biomarkers. Measurements of progesterone and ? human chorionic gonadotropin (?hCG) are still used in clinical practice to exclude the possibility of a viable intrauterine pregnancy (VIUP). We evaluate the predictive value of progesterone, ?hCG, and ?hCG ratio cut-off levels to exclude a VIUP in women with a pregnancy of unknown location.
Oncologic outcomes after splenectomy during initial cytoreductive surgery in advanced epithelial ovarian cancer: a nationwide population-based cohort study
Sherin A. Said,Maaike A. van der Aa,Guus Veldmate,Joanne A. de Hullu,Anne M. van Altena
doi : 10.1111/aogs.14286
Volume 101, Issue 1 p. 56-67
Epithelial ovarian cancer (EOC) patients undergoing splenectomy during cytoreductive surgery represent a small subgroup of patients. Splenic metastases or technical reasons due to extensive upper abdominal disease may require a splenectomy. It has been hypothesized that as the spleen’s antitumor immunologic functions may inhibit cancer growth, splenectomy may promote the growth of residual disease as observed in other cancer types of murine studies. The few studies assessing the impact of splenectomy on the oncologic outcomes of advanced stage EOC patients have reported inconsistent results. It remains unclear whether splenectomy during cytoreductive surgery is justified to achieve complete cytoreduction. The aim of this study was to assess the impact of a splenectomy on perioperative outcomes and survival of advanced stage EOC patients.
Ureteric injuries during hysterectomy—A Norwegian retrospective study of occurrence and claims for compensation over an 11-year period
Merethe Ravlo,Mette Haase Moen,Ida Rashida Khan Bukholm,Marit Lieng,Eszter Vanky
doi : 10.1111/aogs.14293
Volume 101, Issue 1 p. 68-76
Ureteric injury is a rare but serious, iatrogenic complication of hysterectomy. The risk depends on indication for surgery, predisposing risk factors, and peroperative conditions. Our aims were to evaluate and learn from compensation claims to The Norwegian System of Patient Injury Compensation (NPE) for ureteric injury occurring during hysterectomies to predict risk factors, time of identification, symptoms, and consequences, and to relate these cases to injuries registered in The Norwegian Patient Registry.
Provision of long-acting reversible contraception at surgical abortion—A cross-sectional nationwide register study
Sara Hogmark,Niklas Envall,Anna Wikman,Charlotte Skoglund,Helena Kopp Kallner,Susanne Hesselman
doi : 10.1111/aogs.14289
Volume 101, Issue 1 p. 77-83
Provision of long-acting reversible contraception (LARC) at surgical abortion is safe, practical, and leads to higher user rates than does delayed provision. The aim of this study was to explore whether provision of LARC at surgical abortion is associated with known risk factors for subsequent abortions and inconsistent use of contraception, including sociodemographic factors and psychiatric disorders.
A survey of ovarian reserve and quality of life in female survivors of pediatric cancer
Sofia Nilsson,Marianne Jarfelt,Stina Järvholm,Linda Kluge,Ann Thurin-Kjellberg
doi : 10.1111/aogs.14290
Volume 101, Issue 1 p. 84-93
Childhood cancer is rare; the incidence in Sweden is approximately 16 new cases/100 000 children each year. Reduced reproductive function and fertility are well-known side effects of cancer treatment. Anti-Müllerian hormone (AMH) has been shown to correlate well with antral follicle count in healthy women but is currently not recommended as the primary surveillance modality for evaluation of premature ovarian insufficiency in this patient group. Psychological wellbeing related to fertility could affect quality of life and should be included in long-term follow-up. The aim of the study is to present the baseline data from inclusion for a prospective follow-up study of fertility surveillance where both medical and psychological aspects of fertility in female childhood cancer survivors are considered.
The importance of information and support following a suspected second-trimester anomaly that is later discarded: A qualitative study of women's experiences
Lina Thirup,Puk Sandager,Ida Vogel,Stina Lou
doi : 10.1111/aogs.14288
Volume 101, Issue 1 p. 94-101
A second-trimester anatomy scan may identify a suspected minor fetal anomaly and/or “soft marker,” such as choroid plexus cysts or femoral shortening. Such findings can raise a medical concern, as they could indicate severe fetal disease; however, they are also often transient or a “false alarm.” The aim of this study was to explore the experiences of pregnant women, where a medical concern was raised at the second-trimester ultrasound scan and later discarded after follow-up examinations and diagnostic testing.
Detection and clinical outcome of small-for-gestational-age fetuses in the third trimester—A comparison between routine ultrasound examination and examination on indication
Anna Bonnevier,Karel Maršál,Karin Källén
doi : 10.1111/aogs.14278
Volume 101, Issue 1 p. 102-110
Fetal growth restriction is a major risk factor for adverse perinatal outcome. As most of the growth-restricted fetuses are small for gestational age (SGA), an efficient antenatal screening method for SGA fetuses would have a major impact on perinatal health. The aim of this study was to compare the SGA prediction rate achieved with third-trimester routine ultrasound estimation of fetal weight (EFW) with that obtained using ultrasound examination on indication. The secondary aim was to evaluate the clinical outcome in relation to the SGA screening method.
Short-term and long-term outcomes of trichorionic triplet pregnancies with expectant management
Ji Yeon Lee,Seung Mi Lee,Mina Jeong,Sohee Oh,Subeen Hong,Seung-Ah Choe,Jong Kwan Jun
doi : 10.1111/aogs.14281
Volume 101, Issue 1 p. 111-118
Reproductive endocrinologists recommend selective multifetal pregnancy reduction (MFPR) to save at least one or two babies, because triplet pregnancy is known to increase the risk of miscarriage and preterm delivery. However, recently improved obstetric and neonatal care may affect pregnancy outcomes differently in triplet pregnancies, which could alter practice. We compared the maternal, perinatal, and long-term outcomes of triplet pregnancies managed expectantly with those of pregnancies reduced to twins.
Risk factors associated with shortened latency before delivery in outpatients managed for preterm prelabor rupture of membranes
Florian Point,Louise Ghesquiere,Elodie Drumez,Céline Petit,Damien Subtil,Véronique Houfflin-Debarge,Charles Garabedian
doi : 10.1111/aogs.14287
Volume 101, Issue 1 p. 119-126
Preterm prelabor rupture of membranes (PPROM) occurs in 3% of pregnancies and is the main cause (~30%) of premature delivery. Home care seems to be a safe alternative for the management of patients with PPROM, who have a longer latency than those with PPROM managed with conventional hospitalization. We aimed to identify the risk factors associated with a shortened latency before delivery in women with PPROM managed as outpatients.
Hypertensive disorders of pregnancy among women of migrant origin in Finland: A population-based study
Kalpana Bastola,Päivikki Koponen,Natalia Skogberg,Mika Gissler,Tarja I. Kinnunen
doi : 10.1111/aogs.14291
Volume 101, Issue 1 p. 127-134
Hypertensive disorders of pregnancy are a leading cause of maternal and perinatal mortality and morbidity worldwide. We studied the prevalence of hypertensive disorders of pregnancy among women of migrant origin in Finland.
Home management by remote self-monitoring in intermediate- and high-risk pregnancies: A retrospective study of 400 consecutive women
Anne Rahbek Zizzo,Lone Hvidman,Jannie Dalby Salvig,Lone Holst,Morten Kyng,Olav Bjørn Petersen
doi : 10.1111/aogs.14294
Volume 101, Issue 1 p. 135-144
Home management in general is considered to improve patient well-being, patient involvement and cost-effectiveness, for obstetric patients as well. But concerns regarding inclusion of intermediate- and high-risk pregnant women are an issue and a limitation for clinical implementation. This retrospective study evaluated the outcome and safety of extended remote self-monitoring of maternal and fetal health in intermediate- and high-risk pregnancies.
Clinical value of early assessment of hyperfibrinolysis by rotational thromboelastometry during postpartum hemorrhage for the prediction of severity of bleeding: A multicenter prospective cohort study in the Netherlands
Marije Tahitu,Paul I. Ramler,Ada Gillissen,Camila Caram-Deelder,Dacia D. C. A. Henriquez,Moniek P. M. de Maat,Johannes J. Duvekot,Jeroen Eikenboom,Kitty W. M. Bloemenkamp,Thomas van den Akker,Johanna G. van der Bom
doi : 10.1111/aogs.14279
Volume 101, Issue 1 p. 145-152
Coagulopathy may be the result of hyperfibrinolysis and could exacerbate bleeding following childbirth. Timely recognition of hyperfibrinolysis during the earliest stages of postpartum hemorrhage could identify women at risk of more severe blood loss who may benefit from targeted anti-fibrinolytic therapy. Rotational thromboelastometry (ROTEM®) is a point-of-care test that could detect hyperfibrinolysis. The aim of this study was to evaluate whether early assessment of hyperfibrinolysis by ROTEM during postpartum hemorrhage could predict progression to severe postpartum hemorrhage.
Perinatal outcome of dichorionic and monochorionic-diamniotic Finnish twins: a historical cohort study
Annu-Riikka S. Rissanen,Mika Gissler,Irmeli K. Nupponen,Mika E. Nuutila,Riina M. Jernman
doi : 10.1111/aogs.14285
Volume 101, Issue 1 p. 153-162
Although the perinatal mortality of monochorionic twins has been reported to be higher, the role of chorionicity is debated and data from Finland are still lacking. To examine the effect of chorionicity on the main outcome measures, perinatal and neonatal mortality and neonatal morbidity of Finnish twins, a comprehensive population-based historical cohort study was performed at Helsinki University Hospitals.
