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Cover 1

doi : 10.1016/S0091-6749(21)01635-3

Volume 148, Issue 6, December 2021, Page OFC

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Brief Overview of This Month's JACI

doi : 10.1016/S0091-6749(21)01637-7

Volume 148, Issue 6, December 2021, Pages A5-A6

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Table of Contents

doi : 10.1016/S0091-6749(21)01638-9

Volume 148, Issue 6, December 2021, Pages A8, A10-A11, A17-A20, A25

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Editorial Board

doi : 10.1016/S0091-6749(21)01639-0

Volume 148, Issue 6, December 2021, Page A26

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Information for Readers

doi : 10.1016/S0091-6749(21)01641-9

Volume 148, Issue 6, December 2021, Page A33

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News & Notes

doi : 10.1016/S0091-6749(21)01642-0

Volume 148, Issue 6, December 2021, Pages A34-A38

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CME Calendar-AAAAI

doi : 10.1016/S0091-6749(21)01643-2

Volume 148, Issue 6, December 2021, Pages A43-A44

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Food allergy across the globe

VanithaSampathPhDabElissa M.AbramsMD, MPHcdBahmanAdlouMSabCezmiAkdisMDeMübeccelAkdisMD, PhDeHelen A.BroughPhD, MBBS, FRCPCHfgSusanChanMBBS, MDfgPantipaChatchateeMDhR. SharonChinthrajahMDabRenata RodriguesCoccoMD, PhDiAntoineDeschildreMDjPhilippeEigenmannMDkCesarGalvanMDlmRuchiGuptaMD, MPHnoElhamHossnyMD, PhDpJennifer J.KoplinPhDqrGideonLackMBBCH, FRCPCH, MDfgMichaelLevinMBBSstLynette P.ShekMBBS, FRCPCHuMikaMakelaMD, PhDvDavidMendoza-HernandezMDwAntonellaMuraroMD, PhDxNikolaos G.PapadopoulousMD, PhD, FRCPyzRubyPawankarMD, PhDaaKirsten P.PerrettMBBS, FRACP, PhDqrGrahamRobertsDM, FRCPCHbbccddCansinSackesenMDeeHughSampsonMDffMimi L.K.TangMBBS, PhD, FRACP, FRCPAqrAlkisTogiasMDggCarinaVenterPhD, RDhhChristopher MichaelWarrenPhDnoLisa M.WheatleyMD, MPHggGary W.K.WongMD, FRCPCiiKirstenBeyerMDjj?Kari C.NadeauMD, PhDab?HaraldRenzMD, PhDkkll?

doi : 10.1016/j.jaci.2021.10.018

Volume 148, Issue 6, December 2021, Pages 1347-1364

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Food allergy across the globe

doi : 10.1016/j.jaci.2021.10.008

Volume 148, Issue 6, December 2021, Page 1365

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Climate change and global issues in allergy and immunology

Susan E.PachecoMDaGuillermoGuidos-FogelbachMD, PhDbIsabellaAnnesi-MaesanoMD, PhD, DSccRubyPawankarMD, PhDdGennaroD' AmatoMDefPatriciaLatour-StaffeldMDghMarylinUrrutia-PereiraMD, PhDiMatthew J.KesicPhD, PA-CjMichelle L.HernandezMDkAmerican Academy of Allergy, Asthma & Immunology Environmental Exposures and Respiratory Health Committee

doi : 10.1016/j.jaci.2021.10.011

Volume 148, Issue 6, December 2021, Pages 1366-1377

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Epidemiology and management of asthma and atopic dermatitis in Sub-Saharan Africa

ChrysanthiSkevakiMDaJames S.NgochoMDbCarolineAmourMScbPeterSchmid-GrendelmeierMDcBlandina T.MmbagaMDdeHaraldRenzMDabf

doi : 10.1016/j.jaci.2021.10.019

Volume 148, Issue 6, December 2021, Pages 1378-1386

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Association between barrier impairment and skin microbiota in atopic dermatitis from a global perspective: Unmet needs and open questions

RazvigorDarlenskiMD, PhDabAnita L.KozyrskyjBScPhm, PhDcJoachim W.FluhrMDdLuisCaraballoMD, PhDe

doi : 10.1016/j.jaci.2021.10.002

Volume 148, Issue 6, December 2021, Pages 1387-1393

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Hookworm infection: Toward development of safe and effective peptide vaccines

Ahmed O.ShalashMScaWaleed M.HusseinPhDaMariuszSkwarczynskiPhDaIstvanTothPhDab

doi : 10.1016/j.jaci.2021.10.013

Volume 148, Issue 6, December 2021, Pages 1394-1419.e6

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Impact of inhaled pollutants on response to viral infection in controlled exposures

Meghan E.RebuliPhDabcStephanie A.BrockeBSaIlonaJaspersPhDabc

doi : 10.1016/j.jaci.2021.07.002

Volume 148, Issue 6, December 2021, Pages 1420-1429

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Advances in asthma: New understandings of asthma’s natural history, risk factors, underlying mechanisms, and clinical management

Rachel L.MillerMDaMitchell H.GraysonMDbcKaseyStrothmanMDb

doi : 10.1016/j.jaci.2021.10.001

Volume 148, Issue 6, December 2021, Pages 1430-1441

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Inborn errors of immunity: Recent progress

NehaSethMDKaren S.TuanoMDJavierChinenMD, PhD

doi : 10.1016/j.jaci.2021.10.010

Volume 148, Issue 6, December 2021, Pages 1442-1450

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Advances in atopic dermatitis in 2019-2020: Endotypes from skin barrier, ethnicity, properties of antigen, cytokine profiles, microbiome, and engagement of immune cells

TakashiNomuraMD, PhDKenjiKabashimaMD, PhD

doi : 10.1016/j.jaci.2021.10.022

Volume 148, Issue 6, December 2021, Pages 1451-1462

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The Editors’ Choice

doi : 10.1016/j.jaci.2021.10.020

Volume 148, Issue 6, December 2021, Pages 1463-1467

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News Beyond Our Pages

Marc E.RothenbergMD, PhD?JeanBousquetMD?

doi : 10.1016/j.jaci.2021.10.009

Volume 148, Issue 6, December 2021, Pages 1468-1469

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Igniting the firestorm: The inflammasome in autoinflammatory syndromes

FiachraHumphriesPhDKatherine A.FitzgeraldPhD

doi : 10.1016/j.jaci.2021.07.038

Volume 148, Issue 6, December 2021, Pages 1470-1472

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The curious history behind a biologic-enriched cat food: Hyperimmune avian IgY as a means of oral adoptive passive immunization

Joshua A.SteinbergMD, FAAAAI

doi : 10.1016/j.jaci.2021.06.031

Volume 148, Issue 6, December 2021, Pages 1473-1475

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MUCing up the airway in asthma

R. StokesPeeblesJr.MDabc

doi : 10.1016/j.jaci.2021.09.032

Volume 148, Issue 6, December 2021, Pages 1476-1477

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Role of exosomes in allergic asthma: Signaling platforms between the epithelium and type 2 immunity

CharlesPiletteMD, PhD

doi : 10.1016/j.jaci.2021.09.026

Volume 148, Issue 6, December 2021, Pages 1478-1480

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Immunologic memory to SARS-CoV-2 in convalescent COVID-19 patients at 1 year postinfection

HongyanHouPhDa?YandiZhangPhDb?GuoxingTangPhDaYingLuoPhDaWeiLiuMDaChangChengMDcYuhuanJiangMDdZhigangXiongMDaShijiWuMDaZiyongSunPhDaShabeiXuPhDcXionglinFanPhDbFengWangPhDa

doi : 10.1016/j.jaci.2021.09.008

Volume 148, Issue 6, December 2021, Pages 1481-1492.e2

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Genome-wide association study of asthma, total IgE, and lung function in a cohort of Peruvian children

Ayobami T.AkenroyeMD, MPHa?TonyaBrunettiPhDb?KarinaRomeroMD, MSccdMichelleDayaPhDbKanikaKanchanPhDeGautamShankarMSeSameerChavanMSbMeherPreethi BoorgulaMSbElizabeth A.AmplefordPhDfHéllen FreitasFonsecaMScgGregory A.HawkinsPhDhHelena MarianaPitangueira TeixeiraMScgMonicaCampbellMSbNicholasRafaelsMSbAlexandraWintersPhDeEugene R.BleeckerMDiAlvaro A.CruzMDjMauricio L.BarretoMD, PhDkDeborah A.MeyersPhDiVictor E.OrtegaMD, PhD, ATSFfCamila A.FigueiredoPhDgKathleen C.BarnesPhDbWilliamCheckleyMD, PhDclNadia N.HanselMD, MPHc‡Rasika A.MathiasScDe‡

doi : 10.1016/j.jaci.2021.02.035

Volume 148, Issue 6, December 2021, Pages 1493-1504

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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children

Matthew C.AltmanMDabKaitlinFlynnPhDbMario G.RosascoPhDbMatthewDapasPhDcMeyerKattanMDdStephanieLovinsky-DesirMDdGeorge T.O’ConnorMDeMichelle A.GillMDfRebecca S.GruchallaMDfAndrew H.LiuMDgJacqueline A.PongracicMDhGurjit K.Khurana HersheyMDiEdward M.ZorattiMDjStephen J.TeachMDkDeepaRastrogiMBBS, MSkRobert A.WoodMDlLeonard B.BacharierMDmPetraLeBeauPhDnPeter J.GergenMDoAlkisTogiasMDoWilliam W.BusseMDpScottPresnellPhDbJames E.GernMDpCaroleOberPhDcDaniel J.JacksonMDpfor theNIAID Inner City Asthma Consortium

doi : 10.1016/j.jaci.2021.04.035

Volume 148, Issue 6, December 2021, Pages 1505-1514

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Global patterns in anaphylaxis due to specific foods: A systematic review

AlessiaBaseggio ConradoPhDaNandineePatelMDaPaul J.TurnerFRCPCH, PhDab

doi : 10.1016/j.jaci.2021.03.048

Volume 148, Issue 6, December 2021, Pages 1515-1525.e3

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Consensus on treatment goals in hereditary angioedema: A global Delphi initiative

MarcusMaurerMDaEmelAygören-PürsünMDbAleenaBanerjiMDcJonathan A.BernsteinMDdHenrikBalle BoysenePaula J.BusseMDfAnetteBygumMD, DMScghTeresaCaballeroMD, PhDiAnthony J.CastaldoMPAjSandra C.ChristiansenMDkTimothyCraigDOlHenrietteFarkasMD, PhD, DScmAnete S.GrumachMD, PhDnMichihiroHideMD, PhDoConstance H.KatelarisMD, PhDpH. HenryLiMD, PhDqHilaryLonghurstMDrsWilliam R.LumryMDtuMarkusMagerlMDaInmaculadaMartinez-SaguerMDvMarc A.RiedlMD, MSkYuxiangZhiMDwBruceZurawMDkx

doi : 10.1016/j.jaci.2021.05.016

Volume 148, Issue 6, December 2021, Pages 1526-1532

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Metabolome and lipidome derangements during a severe mast cell activation event in a patient with indolent systemic mastocytosis

ThomasBoehmMDa?RobinRistlPhDb?SaijoJosephMDaKarinPetrocziBScaKristapsKlavinsPhDcPeterValentMDdBerndJilmaMDa

doi : 10.1016/j.jaci.2021.03.043

Volume 148, Issue 6, December 2021, Pages 1533-1544

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Epithelial exosomal contactin-1 promotes monocyte-derived dendritic cell–dominant T-cell responses in asthma

MengZhangMD, PhDa?QianyingYuMD, PhDa?WeiTangMD, PhDb?YujiaoWuMSaJiaJiaLvMD, PhDaLinSunMSbGuochaoShiMD, PhDbMinWuMD, PhDc‡JiemingQuMD, PhDb‡CaixiaDiMD, PhDb‡ZhenweiXiaMD, PhDa‡

doi : 10.1016/j.jaci.2021.04.025

Volume 148, Issue 6, December 2021, Pages 1545-1558

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Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency

Henry Y.LuPhDabMehulSharmaMScabAshish A.SharmaPhDemAtilanoLacsonMD, FRCPCfAshleySzpurkoMD, FRCPCjJoanneLuiderBSc, ART, MLTlPoonamDharmani-KhanPhDlAfshinShameliMD, PhD, FCAPlPeter A.BellPhDcdGregory M.T.GuilcherMD, FRCPC, FAAPjVictor A.LewisMD, FRCPCjMarta RojasVasquezMD, FRCPCgSunilDesaiMBChB, DCH, MRCP, FRCPCgLyleMcGonigleMD, FRCPChLuisMurguia-FavelaMD, FRCPCkNicola A.M.WrightMD, MSc, FRCPCkConsolatoSergiMD, MPH, PhD, FRCPC, FCAP, FACScfEytanWineMD, PhD, FRCPCiChristopher M.OverallPhD, FCAHS, FRSCcdSnehaSureshMD, FRCPCg?Stuart E.TurveyMBBS, DPhil, FRCPCab?

doi : 10.1016/j.jaci.2021.04.006

Volume 148, Issue 6, December 2021, Pages 1559-1574.e13

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Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids

AkimasaAdachiMDaTetsuyaHondaMD, PhDabTerukiDainichiMD, PhDaGyoheiEgawaMD, PhDaYosukeYamamotoMD, PhDaTakashiNomuraMD, PhDaSaekoNakajimaMD, PhDaAtsushiOtsukaMD, PhDaMasamitsuMaekawaPhDcNariyasuManoPhDcNaotoKoyanagiPhDdeYasushiKawaguchiDVM, PhDdeToshiakiOhtekiPhDfTakashiNagasawaMD, PhDgKoichiIkutaMD, PhDhAkihikoKitohMD, PhDaKenjiKabashimaMD, PhDai

doi : 10.1016/j.jaci.2021.04.028

Volume 148, Issue 6, December 2021, Pages 1575-1588.e7

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Multiethnic genome-wide and HLA association study of total serum IgE level

MichelleDayaPhDaCoreyCoxMSaNathalieAcevedoMD, PhDbMeher P.BoorgulaMSaMonicaCampbellMSaSameerChavanMSaMichael H.ChoMDcGloria L.DavidPhD, MHScdPriyadarshiniKachrooPhDeJessicaLasky-SuPhDeXingnanLiPhDfCaitlin P.McHughPhDgDandiQiaoPhDeNicholasRafaelsMSaLisa A.BeckMDhEugene R.BleeckerMDfLuisCaraballoMD, PhDbAdrienne L.CupplesPhDiCamila A.FigueiredoPhDjRichard L.GalloMD, PhDkJonHanifinMDlNadia N.HanselMDmTissa R.HataMDkCraig P.HershMDeJenniferKnight-MaddenMBBS, PhDnDonald Y.M.LeungMD, PhDoEmmaGuttman-YasskyMD, PhDpDeborah A.MeyersPhDfGeorgeO’ConnorPhDqCaroleOberPhDrPeck Y.OngMDsVictor E.OrtegaMD, PhDtAmy S.PallerMDuNirupamaPutchaMDmRobert M.ReedMDvLynda C.SchneiderMDwEdwin K.SilvermanMD, PhDeMark K.SlifkaPhDlJonathan M.SpergelMDxRamachandran S.VasanMDyzKarine A.Viaud-MartinezMSaaHaroldWatsonMDbbScott T.WeissMD, PhDeNHLBI Trans-Omics for Precision Medicine (TOPMed) ConsortiumIngoRuczinskiPhDccTerri H.BeatyPhDddRasika A.MathiasScDddKathleen C.BarnesPhDa

doi : 10.1016/j.jaci.2021.09.011

Volume 148, Issue 6, December 2021, Pages 1589-1595

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The FADS mouse: A novel mouse model of atopic keratoconjunctivitis

SatoshiNunomuraPhDaIsaoKitajimaMD, PhDbYasuhiroNanriPhDaMidoriKitajimaBSbNaokoEjiriBSbI-ShuanLaiBSaNaokoOkadaPhDcKenjiIzuharaMD, PhDa

doi : 10.1016/j.jaci.2021.05.017

Volume 148, Issue 6, December 2021, Pages 1596-1602.e1

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Corrigenda

doi : 10.1016/j.jaci.2021.09.002

Volume 148, Issue 6, December 2021, Page 1603

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Corrigenda

doi : 10.1016/j.jaci.2021.09.012

Volume 148, Issue 6, December 2021, Page 1603

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