British Journal of Anaesthesia




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Editorial Board

doi : 10.1016/S0007-0912(21)00666-8

Volume 127, Issue 6, December 2021, Page i

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Associate Editorial Board

doi : 10.1016/S0007-0912(21)00667-X

Volume 127, Issue 6, December 2021, Page ii

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Contents

doi : 10.1016/S0007-0912(21)00669-3

Volume 127, Issue 6, December 2021, Pages iv-vi

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Six Sigma in surgery: how to create a safer culture in the operating theatre using innovative technology

Anne Sophie H.M.van Dalen1JeanettStrandbygaard2Isabellevan Herzeele3SylvainBoet4Teodor P.Grantcharov5Marlies P.Schijven56

doi : 10.1016/j.bja.2021.08.023

Volume 127, Issue 6, December 2021, Pages 817-820

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The ethics of quality improvement studies: do the needs of the many outweigh the needs of the few?

Peter A.Goldstein123

doi : 10.1016/j.bja.2021.08.018

Volume 127, Issue 6, December 2021, Pages 821-824

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(Im)precise trial descriptions

Daniel I.Sessler

doi : 10.1016/j.bja.2021.09.013

Volume 127, Issue 6, December 2021, Pages 824-825

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Predicting acute kidney injury after cardiac surgery: much work still to be done

David R.McIlroy12

doi : 10.1016/j.bja.2021.09.005

Volume 127, Issue 6, December 2021, Pages 825-828

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PEACHY, another fruitful study

NicolaDisma1Anthony R.Absalom2

doi : 10.1016/j.bja.2021.09.007

Volume 127, Issue 6, December 2021, Pages 828-830

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The PATH to patient safety

Alexander F.Arriaga1234

doi : 10.1016/j.bja.2021.09.006

Volume 127, Issue 6, December 2021, Pages 830-833

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Convalescent plasma for COVID-19: a meta-analysis, trial sequential analysis, and meta-regression

Timothy A.C.Snow1†NaveedSaleem1†GarethAmbler2EleniNastouli3Laura E.McCoy4MervynSinger1NishkanthaArulkumaran1

doi : 10.1016/j.bja.2021.07.033

Volume 127, Issue 6, December 2021, Pages 834-844

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies, particularly those preventing interaction between the viral spike receptor-binding domain and the host angiotensin-converting enzyme 2 receptor, may prevent viral entry into host cells and disease progression.

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Heterogeneous impact of hypotension on organ perfusion and outcomes: a narrative review

LingzhongMeng

doi : 10.1016/j.bja.2021.06.048

Volume 127, Issue 6, December 2021, Pages 845-861

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Prediction of acute kidney injury after cardiac surgery from preoperative N-terminal pro-B-type natriuretic peptide

ChunrongWang1†YuchenGao1†YuTian1†YuefuWang2‡WeiZhao3‡Daniel I.Sessler4YuanJia1BingyangJi5XiaolinDiao3XinyiXu3JianhuiWang1JunLi1SudenaWang1JiaLiu1

doi : 10.1016/j.bja.2021.08.015

Volume 127, Issue 6, December 2021, Pages 862-870

Acute kidney injury (AKI) is common after cardiac surgery and is difficult to predict. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is highly predictive for perioperative cardiovascular complications and may also predict renal injury. We therefore tested the hypothesis that preoperative NT-proBNP concentration is associated with renal injury after major cardiac surgery.

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Ultrasound guidance for urgent arterial and venous catheterisation: randomised controlled study

StephenLazaar1AmélieMazaud1ClaireDelsuc1MaevaDurand1BenjaminDelwarde1SophieDebord1BaptisteHengy1GuillaumeMarcotte1BernardFloccard1FrédéricDailler2PierreChirossel3PascaleBureau-Du-Colombier4JulienBerthiller5ThomasRimmelé16

doi : 10.1016/j.bja.2021.07.023

Volume 127, Issue 6, December 2021, Pages 871-878

Haemodynamically unstable patients often require arterial and venous catheter insertion urgently. We hypothesised that ultrasound-guided arterial and venous catheterisation would reduce mechanical complications.

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Risk of perioperative thyroid storm in hyperthyroid patients: a systematic review

Nikkide Mul1JillDamstra2Els J.M.Nieveen van Dijkum34StefanFischli5Cor J.Kalkman1Willem-Jan M.Schellekens16Rogier V.Immink2

doi : 10.1016/j.bja.2021.06.043

Volume 127, Issue 6, December 2021, Pages 879-889

Thyroid storm is a feared complication in patients with hyperthyroidism undergoing surgery. We assessed the risk of thyroid storm for different preoperative treatment options for patients with primary hyperthyroidism undergoing surgery.

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Incidence and risk factors for near-fatal and fatal outcomes after perioperative and periprocedural anaphylaxis in the USA, 2005–2014

AlexeiGonzalez-Estrada1Ronna L.Campbell2IsmaelCarrillo-Martin1J. RossRenew3Matthew A.Rank4Gerald W.Volcheck5

doi : 10.1016/j.bja.2021.06.036

Volume 127, Issue 6, December 2021, Pages 890-896

The incidence of fatal and near-fatal outcomes after perioperative anaphylaxis is unknown in the USA. Previously identified risk factors of neuromuscular-blocker-induced fatal perioperative anaphylaxis include male sex, obesity, and use of beta blockers. We examined the incidence of fatal and near-fatal outcomes after perioperative anaphylaxis in the USA and the underlying risk factors using a large national database.

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DALES, Drug Allergy Labels in Elective Surgical patients: a prospective, multicentre cross-sectional study of prevalence, nature and anaesthetists’ approach to management

CarolineThomas1SamClark23DavidFallaha4MichelleWilson5Philip M.Hopkins1SinisaSavic5LouiseSavic1Research and Audit Federation of Trainees (RAFT) group

doi : 10.1016/j.bja.2021.05.026

Volume 127, Issue 6, December 2021, Pages 897-904

We sought to define the prevalence and nature of patient-reported drug allergies, determine their impact on prescribing, and explore drug allergy knowledge and attitudes amongst anaesthetists.

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Methodological quality of systematic reviews comprising clinical practice guidelines for cardiovascular risk assessment and management for noncardiac surgery

Samuel M.Jacobsen1AlexanderDouglas1Caleb A.Smith1WillRoberts2RyanOttwell13BensonOglesby2CoyYasler2TrevorTorgerson1MicahHartwell1MattVassar1

doi : 10.1016/j.bja.2021.08.016

Volume 127, Issue 6, December 2021, Pages 905-916

Cardiac assessment in noncardiac surgery clinical practice guidelines should be supported by the highest-quality evidence such as that offered by systematic reviews. Currently, the methodological and reporting quality of these studies remains unknown.

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Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study

Jeffrey N.Browndyke1234Mary C.Wright5RosaYang6AyeshaSyed57JohnPark56AshleyHall5KatherineMartucci45Michael J.Devinney5LeslieShaw8TeresaWaligorska8Eugene W.Moretti5Heather E.Whitson910Harvey J.Cohen910Joseph P.Mathew5MilesBerger24569

doi : 10.1016/j.bja.2021.08.012

Volume 127, Issue 6, December 2021, Pages 917-928

Cognitive dysfunction after surgery is a major issue in older adults. Here, we determined the effect of APOE4 on perioperative neurocognitive function in older patients.

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Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice

YongyanYang12†FengLiang2†JieGao34YuanlinDong2YiyingZhang2GuangYang5Sulpicio G.Soriano6Hua-JunFeng4ZhongcongXie2

doi : 10.1016/j.bja.2021.08.028

Volume 127, Issue 6, December 2021, Pages 929-941

Sevoflurane anaesthesia induces phosphorylation of the microtubule-associated protein tau and cognitive impairment in neonatal, but not adult, mice. The underlying mechanisms remain largely to be determined. Sex hormones can be neuroprotective, but little is known about the influence of testosterone on age-dependent anaesthesia effects.

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Use of labour neuraxial analgesia according to maternal immigration status: a national cross-sectional retrospective population-based study in France

MyriamBrebion1Marie-PierreBonnet12PriscilleSauvegrain1Marie-JosèpheSaurel-Cubizolles1BéatriceBlondel1CatherineDeneux-Tharaux1ElieAzria13

doi : 10.1016/j.bja.2021.08.011

Volume 127, Issue 6, December 2021, Pages 942-952

Disparities in neuraxial analgesia use for childbirth by maternal origin have been reported in high-resource countries. We explored the association between maternal immigrant status (characterised separately by geographic continental origin and Human Development Index [HDI] of maternal country of birth) and neuraxial analgesia use. We hypothesised that immigrant women from low-resource countries may have more limited access to neuraxial analgesia than native French women.

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Prevalence of PErioperAtive CHildhood obesitY in children undergoing general anaesthesia in the UK: a prospective, multicentre, observational cohort study

Zoë A.Burton1†RosieLewis2†TomBennett3†David J.McLernon4Paediatric Anaesthesia Trainee Research Network‡ThomasEngelhardt5Peter B.Brooks6Mark R.Edwards3

doi : 10.1016/j.bja.2021.07.034

Volume 127, Issue 6, December 2021, Pages 953-961

Childhood obesity has become a serious global healthcare challenge. No UK data currently define its anaesthetic and perioperative implications. We aimed to determine obesity prevalence amongst UK children undergoing general anaesthesia and the incidence of predefined adverse perioperative events, and to compare perioperative obesity rates with National Child Measurement Programme (NCMP) data.

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Standardised handover process with checklist improves quality and safety of care in the postanaesthesia care unit: the Postanaesthesia Team Handover trial

FrançoisJaulin1ThomasLopes2FredericMartin12

doi : 10.1016/j.bja.2021.07.002

Volume 127, Issue 6, December 2021, Pages 962-970

Miscommunication is a leading cause of preventable incidents in healthcare. A number of checklists have been created in an attempt to improve patient outcomes with only a small impact. However, the 2009 WHO Surgical Safety Checklist demonstrated benefits in terms of reduced morbidity and mortality. Our aim was to determine whether use of a Postanaesthesia Team Handover (PATH) checklist would reduce hypoxaemic events in the postanaesthesia care unit (PACU).

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Associations of form and function of speaking up in anaesthesia: a prospective observational study

RahelLemke12Michael J.Burtscher34Julia C.Seelandt2BastianGrande12†MichaelaKolbe25†

doi : 10.1016/j.bja.2021.08.014

Volume 127, Issue 6, December 2021, Pages 971-980

Speaking up with concerns in the interest of patient safety has been identified as important for the quality and safety of patient care. The study objectives were to identify how anaesthesia care providers speak up, how their colleagues react to it, whether there is an association among speak up form and reaction, and how this reaction is associated with further speak up.

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Specifying perioperative nonsteroidal anti-inflammatory drug use in trials of the effect of anaesthetic technique on oncologic outcomes. Comment on Br J Anaesth 2021; 127: 65–74

KalpanaBalakrishnanPunithaChockalingam

doi : 10.1016/j.bja.2021.07.028

Volume 127, Issue 6, December 2021, Pages e189-e190

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Specifying perioperative NSAID use in trials of the effect of anaesthetic technique on oncologic outcomes. Response to Br J Anaesth 2021; 127: e189–e190

WiebkeFalk12AnilGupta3

doi : 10.1016/j.bja.2021.08.021

Volume 127, Issue 6, December 2021, Pages e190-e191

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Equipment for cricothyroidotomy: optimum tube size needs a compatible bougie. Comment on Br J Anaesth 2021; 127: 479–86

Conan L.McCaul1EdwardBick2RichardVanner3†

doi : 10.1016/j.bja.2021.09.001

Volume 127, Issue 6, December 2021, Pages e191-e192

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Effect of high-flow nasal oxygen use on oxygen flow at the surgical site: a pilot study

HiroyukiSeki12KojiFukagata3ShingoIto2ReinaOkada2TakashiOuchi2

doi : 10.1016/j.bja.2021.08.024

Volume 127, Issue 6, December 2021, Pages e192-e195

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Study of peripheral nerve trauma from subepineural injection of the brachial plexus in pigs. Comment on Br J Anaesth 2021; 127: e153–e163

Richard EddieClutton1Ronald S.Jones2

doi : 10.1016/j.bja.2021.09.003

Volume 127, Issue 6, December 2021, Pages e195-e196

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Study of peripheral nerve trauma from subepineural injection of the brachial plexus in pigs. Response to Br J Anaesth 2021; 127: e195–e196

GraemeMcLeod1ChristineDemore2YohannesSoenjaya3AnuChandra4

doi : 10.1016/j.bja.2021.09.002

Volume 127, Issue 6, December 2021, Pages e196-e197

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Influence of the World Wars on vital sign monitoring technology

ShawnSud1Benjamin E.Steinberg12DavidLevin1AsadSiddiqui1

doi : 10.1016/j.bja.2021.09.004

Volume 127, Issue 6, December 2021, Pages e198-e199

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Postoperative pain management in Chinese hospitals: a national survey

YafengWang1†DongYang2†ShuaiZhao1LinlinHan1FengXu1ShiqianHuang1YuanyuanDing1DalinDeng1WeidongMi3XiangdongChen1Pain Group of the Chinese Society of Anesthesiology

doi : 10.1016/j.bja.2021.08.026

Volume 127, Issue 6, December 2021, Pages e200-e202

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Persistent postoperative prescribing of opioids: a warning from the west? Comment on Br J Anaesth 2021; 126: 1192–9

HelenKennedy1ZeeshanMalik1DavandraPatel2

doi : 10.1016/j.bja.2021.08.025

Volume 127, Issue 6, December 2021, Pages e202-e204

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Chronic disabling postpartum headache after unintentional dural puncture during epidural anaesthesia: a prospective cohort study. Comment on Br J Anaesth 2021; 127: 600–7

Christopher W.Liu12Leonard W.Loh23

doi : 10.1016/j.bja.2021.09.015

Volume 127, Issue 6, December 2021, Pages e204-e205

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Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study

DavidKunkel1MargaretParker1CameronCasey1BryanKrause1Robert A.Pearce1RichardLennertz1Robert D.Sanders234

doi : 10.1016/j.bja.2021.08.027

Volume 127, Issue 6, December 2021, Pages e205-e207

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Iron status in 1041 non-anaemic patients scheduled for elective reduction mammoplasty: prevalence of iron depletion, iron deficiency, and low iron stores

AristideNtahe1†KevinSerror2†DavidBoccara2MarcChaouat2MauriceMimoun2BenoitPlaud3

doi : 10.1016/j.bja.2021.09.011

Volume 127, Issue 6, December 2021, Pages e207-e210

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Accurate core temperature measurement during Caesarean delivery. Comment on Br J Anaesth 2021; 126: 500–15

J.M.JackH.E.EllicottP.T.ThorburnA.ChakladarC.M.HarperSouth East Anaesthetic Research Chain (SEARCH)

doi : 10.1016/j.bja.2021.09.012

Volume 127, Issue 6, December 2021, Pages e210-e211

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Therapeutic potential of long-acting opioids and opioid antagonists for SARS-CoV-2 infection

MarieEagleton1SiobhanStokes1FionaFenton1EamonKeenan2

doi : 10.1016/j.bja.2021.08.022

Volume 127, Issue 6, December 2021, Pages e212-e214

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Anaesthesia drugs, SARS-CoV-2, and the sigma-1 receptor: a complex affair. Comment on Br J Anaesth 2021; 127: e32–4

AmitJain1MassimoLamperti1D. JohnDoyle2Francisco A.Lobo1

doi : 10.1016/j.bja.2021.09.008

Volume 127, Issue 6, December 2021, Pages e215-e218

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Perioperative Medicine: Managing for Outcome, 2nd edition, Mark F. Newman, Lee A. Fleisher, Clifford Ko, Michael Mythen (Eds.), Elsevier (2021), pp. 720. £145.79. ISBN 9780323567244

BarbaraPhilips

doi : 10.1016/j.bja.2021.08.019

Volume 127, Issue 6, December 2021, Page 981

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Corrigendum to ‘Preoperative opioid use: a modifiable risk factor for poor postoperative outcomes’ (Br J Anaesth 2021; 127: 327-31)

JaneQuinlan1NicholasLevy2Dileep N.Lobo34Pamela E.Macintyre5

doi : 10.1016/j.bja.2021.09.009

Volume 127, Issue 6, December 2021, Pages 982-983

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