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Use of Real World Data (RWD) to generate Real World Evidence (RWE) in gynecologic surgery
Martin Rudnicki
doi : 10.1111/aogs.14292
Volume 100, Issue 12 p. 2133-2134
Diagnostic criteria for retained products of conception—A scoping review
Charlotte C. Hamel,Steffi van Wessel,Alasdair Carnegy,Sjors F. P. J. Coppus,Marc P. M. L. Snijders,Justin Clark,Mark H. Emanuel
doi : 10.1111/aogs.14229
Volume 100, Issue 12 p. 2135-2143
Numerous studies have been performed assessing optimal treatment regimens for evacuating (retained) products of conception from the uterus, but standardized criteria for diagnosing retained products of conception (RPOC) are still lacking. We aim to provide an overview of diagnostic criteria in current literature, used to diagnose RPOC after induced first-trimester abortion or early pregnancy loss.
The prognostic significance of HPV, p16, and p53 protein expression in vaginal cancer: A systematic review
Christina L. Rasmussen,Hanna K. Bertoli,Freja L. Sand,Alexander K. Kjær,Louise T. Thomsen,Susanne K. Kjær
doi : 10.1111/aogs.14260
Volume 100, Issue 12 p. 2144-2156
Human papillomavirus (HPV), p16, and p53 have been investigated as prognostic markers in various HPV-related cancers. Within the field of vaginal cancer, however, the evidence remains sparse. In this systematic review, we have compiled the presently published studies on the prognostic significance of HPV and immunohistochemical expression of p16 and p53 among women with vaginal cancer.
Menstrual pain and sexual health in mothers—A cross-sectional study in the Danish National Birth Cohort
Sarah Hjorth,Dorte Rytter,Axel Forman,Helene Kirkegaard,Jørn Olsen,Ellen A. Nohr
doi : 10.1111/aogs.14272
Volume 100, Issue 12 p. 2157-2166
Prevalence and consequences of menstrual pain have mainly been studied in younger women. We aimed to describe the prevalence of menstrual pain in mothers and its association with sexual problems.
Risk factors for surgical site infection following cesarean delivery: A hospital-based case–control study
Sedina Atic Kvalvik,Svein Rasmussen,Heidi Frances Thornhill,Elham Baghestan
doi : 10.1111/aogs.14235
Volume 100, Issue 12 p. 2167-2175
Cesarean section is the single most important risk factor for postpartum infection. Where the rest of the world shows increasing trends, the cesarean section rates are low in Norway and risk factors for infection after cesarean section may differ in high and low cesarean section settings. The goal of this study was to examine independent risk factors for surgical site infection after cesarean delivery in a setting of low cesarean section rates.
Live surgery of colorectal endometriosis broadcasted from a surgeon’s routine operating theater is not associated with higher complications rate
Horace Roman,Maria Prosszer,Jamil Marabha,Benjamin Merlot,Damien Forestier,Myriam Noailles,Loïc Marpeau,Jean-Jacques Tuech
doi : 10.1111/aogs.14264
Volume 100, Issue 12 p. 2176-2185
Although live surgeries are routinely included in surgical congress programs, they are the subject of an ongoing debate in terms of patient safety and teaching value. The goal of our study was to assess the risk of postoperative complications related to live surgery broadcast from the surgeon's routine theater, in patients managed for deep endometriosis infiltrating the digestive tract.
Comparing risk of repeat surgery for stress urinary incontinence after mid-urethral slings and polyacrylamide hydrogel
Rune Svenningsen,Sissel Hegdahl Oversand,Hjalmar August Schiøtz,Sigurd Kulseng-Hanssen
doi : 10.1111/aogs.14271
Volume 100, Issue 12 p. 2186-2192
Stress and urgency urinary incontinence one year after a first birth—prevalence and risk factors. A prospective cohort study
Markus H. Jansson,Karin Franzén,Gunilla Tegerstedt,Ayako Hiyoshi,Kerstin Nilsson
doi : 10.1111/aogs.14275
Volume 100, Issue 12 p. 2193-2201
Few prospective studies have examined the effect of pregnancy and childbirth on stress and urgency urinary incontinence separately. The aim of the present study was to assess the extent to which pregnancy, vaginal delivery, and vaginal delivery characteristics affect the risk of significant stress and urgency incontinence 1 year after delivery.
Second trimester induced abortions due to fetal anomalies—a population-based study of diagnoses, examinations and clinical management
Agnes Edling,Linda Lindström,Eva Bergman
doi : 10.1111/aogs.14230
Volume 100, Issue 12 p. 2202-2208
Two-thirds of induced abortions after gestational week (gw) 18 are performed due to fetal anomalies. The potential of the fetus to survive outside the uterus after birth is the upper limit for induced abortions in Sweden. Due to advances in neonatal medicine, fetal viability and the upper limit of late induced abortions have been converging over the last few decades. The aim of the study was to examine clinical management of fetal anomalies, including time frames, leading to second trimester abortions.
A value of soluble Toll-like receptor 2 and 4 in vaginally obtained amniotic fluid for the prediction of histological chorioamnionitis
Greta Balciuniene,Violeta Gulbiniene,Greta Kvederaite-Budre,Irena Dumalakiene,Rita Viliene,Ingrida Pilypiene,Grazina S. Drasutiene,Diana Ramasauskaite
doi : 10.1111/aogs.14228
Volume 100, Issue 12 p. 2209-2215
This study was conducted to evaluate soluble Toll-like receptor 2 (sTLR-2) and soluble Toll-like receptor 4 (sTLR-4) levels in vaginally obtained amniotic fluid and investigate their value in the prediction of histological chorioamnionitis (HCA).
Management and clinical consequences of red blood cell antibodies in pregnancy: A population-based cohort study
Shengxin Liu,Gunilla Ajne,Agneta Wikman,Caroline Lindqvist,Marie Reilly,Eleonor Tiblad
doi : 10.1111/aogs.14261
Volume 100, Issue 12 p. 2216-2225
Anti-D alloimmunization is the most common cause of severe hemolytic disease of the fetus and newborn (HDFN). The management of pregnancies affected by less frequent red blood cell (RBC) antibodies poses a challenge to clinicians, and perinatal outcomes are less well described. This study aimed to describe the frequency of clinically significant RBC antibodies in our pregnant population and analyze the risk of prenatal and postnatal treatment for HDFN in relation to our national risk classification system and management guidelines.
The impact of early pregnancy complications on completed family size—A nationwide, registry-based cohort study with 40 years of data
Astrid M. Kolte,David Westergaard,Øjvind Lidegaard,Søren Brunak,Henriette S. Nielsen
doi : 10.1111/aogs.14265
Volume 100, Issue 12 p. 2226-2233
The impact of early pregnancy complications on completed family size is unknown. Here, we hypothesize that early pregnancy complications and adverse outcomes may influence family size.
Utilizations and outcomes of intra-arterial balloon occlusion at cesarean hysterectomy for placenta accreta spectrum
Koji Matsuo,Shinya Matsuzaki,Nicole L. Vestal,Rauvynne N. Sangara,Rachel S. Mandelbaum,Kazuhide Matsushima,Maximilian Klar,Joseph G. Ouzounian
doi : 10.1111/aogs.14266
Volume 100, Issue 12 p. 2234-2243
This study examined national-level trends, characteristics, and perioperative outcomes of women who had intra-arterial balloon occlusion at cesarean hysterectomy for placenta accreta spectrum (PAS).
The use of functional placental magnetic resonance imaging for assessment of the placenta after prolonged preterm rupture of the membranes in vivo: A pilot study
Jana Hutter,Laurence Jackson,Alison Ho,Carla Avena Zampieri,Joseph V. Hajnal,Mudher Al-Adnani,Surabhi Nanda,Andrew H. Shennan,Rachel M. Tribe,Deena Gibbons,Mary A. Rutherford,Lisa Story
doi : 10.1111/aogs.14267
Volume 100, Issue 12 p. 2244-2252
Preterm prelabor rupture of membranes (PPROM) complicates 3% of pregnancies in the UK. Where delivery does not occur spontaneously, expectant management until 37 weeks of gestation is advocated, unless signs of maternal infection develop. However, clinical presentation of maternal infection can be a late sign and injurious fetal inflammatory responses may already have been activated. There is therefore a need for more sensitive markers to aid optimal timing of interventions. At present there is no non-invasive test in clinical practice to assess for infection in the fetal compartment and definitive diagnosis of chorioamnionitis is by histological assessment of the placenta after delivery. This study presents comprehensive functional placental magnetic resonance imaging (MRI) quantification, already used in other organ systems, to assess for infection/inflammation, in women with and without PPROM aiming to explore its use as a biomarker for inflammation within the feto-placental compartment in vivo.
Preterm birth among women with and without severe acute respiratory syndrome coronavirus 2 infection
Matthew J. Blitz,Rachel P. Gerber,Moti Gulersen,Weiwei Shan,Andrew C. Rausch,Lakha Prasannan,Natalie Meirowitz,Burton Rochelson
doi : 10.1111/aogs.14269
Volume 100, Issue 12 p. 2253-2259
Studies directly comparing preterm birth rates in women with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited. Our objective was to determine whether preterm birth was affected by SARS-CoV-2 infection within a large integrated health system in New York with a universal testing protocol.
Success rate of external cephalic version in relation to the woman’s body mass index and other factors—a population-based cohort study
Emelie Svensson,Daniel Axelsson,Marie Nelson,Sofia Nevander,Marie Blomberg
doi : 10.1111/aogs.14270
Volume 100, Issue 12 p. 2260-2267
The aim of this study was to evaluate the impact of women’s body mass index (BMI) on the probability of a successful external cephalic version (ECV).
A prospective cohort study of confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy evaluating SARS-CoV-2 antibodies in maternal and umbilical cord blood and SARS-CoV-2 in vaginal swabs
Julie Milbak,Victoria M. F. Holten,Paul Bryde Axelsson,Jane Marie Bendix,Anna J. M. Aabakke,Lene Nielsen,Martin Barfred Friis,Claus A. J. Jensen,Ellen Christine Leth Løkkegaard,Tina Elisabeth Olsen,Line Rode,Tine Dalsgaard Clausen
doi : 10.1111/aogs.14274
Volume 100, Issue 12 p. 2268-2277
Evidence about the consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is rapidly increasing; however, data on antibody response and risk of transmission during pregnancy and delivery are still limited. The aim of this study was to evaluate if SARS-CoV-2 is detectable in vaginal swabs and whether antibodies against SARS-CoV-2 are present in maternal and umbilical cord blood of pregnant women with confirmed SARS-CoV-2.
Recurrence of postpartum hemorrhage in relatives: A population-based cohort study
Lorentz Erland Linde,Cathrine Ebbing,Dag Moster,Jørg Kessler,Elham Baghestan,Mika Gissler,Svein Rasmussen
doi : 10.1111/aogs.14262
Volume 100, Issue 12 p. 2278-2284
Studies on the family aggregation of postpartum hemorrhage (PPH) are scarce and with inconsistent results, and to what extent current birthweight influences recurrence between relatives remains to be studied. Further, family aggregation of PPH has been studied from an individual, but not from a public heath perspective. We aimed to investigate family aggregation of PPH in Norway, how birthweight influences these effects, and to estimate the proportion of PPH cases attributable to a family history of PPH and current birthweight.
Hypoxic ischemic encephalopathy in offspring of immigrant women in Sweden: A population-based cohort study
Anna E. Törn,Erik Lampa,Anna-Karin Wikström,Maria Jonsson
doi : 10.1111/aogs.14234
Volume 100, Issue 12 p. 2285-2293
One in four women giving birth in Sweden is foreign-born. Immigrant status has been suggested as a risk factor for adverse perinatal outcomes. It is not known if infants to foreign-born women have an increased risk of severe birth asphyxia, or which factors might mediate such association.
The association between intrapartum opioid fentanyl and early breastfeeding: A prospective observational study
Hanna Oommen,Tor Oddbjørn Tveit,Leif T. Eskedal,Rachel Myr,David M. Swanson,Ingvild Vistad
doi : 10.1111/aogs.14268
Volume 100, Issue 12 p. 2294-2302
Intrapartum opioids in labor may interfere with the early breastfeeding phase and cause breastfeeding difficulties. This study examines the effects of intrapartum fentanyl given intravenously (IV) or through epidural analgesia (EDA) on early breastfeeding.
Live surgery “at home” is as safe as non-live surgery when performed by a surgeon who can do it safely under such conditions
Shigeki Matsubara,Daisuke Matsubara,Yuji Takei
doi : 10.1111/aogs.14284
Volume 100, Issue 12 p. 2303-2303
