British Journal of Anaesthesia




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Editorial Board

doi : 10.1016/S0007-0912(21)00590-0

Volume 127, Issue 5, November 2021, Page i

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Associate Editorial Board

doi : 10.1016/S0007-0912(21)00591-2

Volume 127, Issue 5, November 2021, Page ii

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Contents

doi : 10.1016/S0007-0912(21)00593-6

Volume 127, Issue 5, November 2021, Pages iv-vi

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Capnography use in the critical care setting: why do clinicians fail to implement this safety measure?

VincenzoRussotto1Tim M.Cook23

doi : 10.1016/j.bja.2021.08.010

Volume 127, Issue 5, November 2021, Pages 661-664

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The quagmire of postoperative delirium: does dose matter?

AmyGaskellJamieSleigh

doi : 10.1016/j.bja.2021.08.008

Volume 127, Issue 5, November 2021, Pages 664-666

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Anaesthetic depth and delirium: a challenging balancing act

Elizabeth L.Whitlock1Eric R.Gross2C. RyanKing3Michael S.Avidan3

doi : 10.1016/j.bja.2021.08.003

Volume 127, Issue 5, November 2021, Pages 667-671

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Improving prediction to prevent perioperative morbidity

Jessica K.Goeller12KarstenBartels13

doi : 10.1016/j.bja.2021.08.004

Volume 127, Issue 5, November 2021, Pages 671-674

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Continuous ward monitoring: the selection, monitoring, alarms, response, treatment (SMART) road map

MoritzFlick1BerndSaugel12

doi : 10.1016/j.bja.2021.07.016

Volume 127, Issue 5, November 2021, Pages 675-677

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Need for a new paradigm in the design of alarms for patient monitors and medical devices

Craig S.Webster1PenelopeSanderson2

doi : 10.1016/j.bja.2021.08.001

Volume 127, Issue 5, November 2021, Pages 677-680

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Effect of Hypotension Prediction Index-guided intraoperative haemodynamic care on depth and duration of postoperative hypotension: a sub-study of the Hypotension Prediction trial

JimmySchenk1MarijeWijnberge1Jolanda M.Maaskant3Markus W.Hollmann1LiselotteHol1Rogier V.Immink1Alexander P.Vlaar2Björn J.P.van der Ster1Bart F.Geerts1Denise P.Veelo1

doi : 10.1016/j.bja.2021.05.033

Volume 127, Issue 5, November 2021, Pages 681-688

Intraoperative and postoperative hypotension are associated with morbidity and mortality. The Hypotension Prediction (HYPE) trial showed that the Hypotension Prediction Index (HPI) reduced the depth and duration of intraoperative hypotension (IOH), without excess use of intravenous fluid, vasopressor, and/or inotropic therapies. We hypothesised that intraoperative HPI-guided haemodynamic care would reduce the severity of postoperative hypotension in the PACU.

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Key dimensions of innovations in workplace-based assessment for postgraduate medical education: a scoping review

Jennifer M.Weller12TiesCoomber1YanChen1Damian J.Castanelli3

doi : 10.1016/j.bja.2021.06.038

Volume 127, Issue 5, November 2021, Pages 689-703

Specialist training bodies continue to devise innovative methods of gathering information on trainee workplace performance to meet the requirements of competency-based medical education. We reviewed recent innovations in workplace-based assessment (WBA) tools to identify strengths, weaknesses, and trade-offs inherent in their design and use.

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Anaesthetic depth and delirium after major surgery: a randomised clinical trial

Lisbeth A.Evered123†Matthew T.V.Chan4RuquanHan5Mandy H.M.Chu4Benny P.Cheng4David A.Scott23Kane O.Pryor1Daniel I.Sessler6RobertVeselis17ChristopherFrampton8MatthewSumner9AdeAyeni9Paul S.Myles10DouglasCampbell911KateLeslie31213Timothy G.Short911

doi : 10.1016/j.bja.2021.07.021

Volume 127, Issue 5, November 2021, Pages 704-712

Postoperative delirium is a serious complication of surgery associated with prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to determine whether targeting bispectral index (BIS) readings of 50 (light anaesthesia) was associated with a lower incidence of POD than targeting BIS readings of 35 (deep anaesthesia).

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Development and external validation of a prognostic model for ischaemic stroke after surgery

KatharinaPlatzbecker12†Stephanie D.Grabitz12†DanaRaub12Maíra I.Rudolph1SabineFriedrich12NathanVinzant23TobiasKurth4ChristianWeimar56Deepak L.Bhatt7AlaNozari8Timothy T.Houle1XinlingXu2MatthiasEikermann2910

doi : 10.1016/j.bja.2021.05.035

Volume 127, Issue 5, November 2021, Pages 713-721

There is an under-recognised patient cohort at elevated risk of postoperative ischaemic stroke. We aimed to develop and validate a prognostic model for the identification of such patients at high risk of ischaemic stroke within 1 yr after noncardiac surgery.

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Moderators of the association between attention-deficit/hyperactivity disorder and exposure to anaesthesia and surgery in children

YuShi1Hayley J.Dykhoff2Lindsay R.H.Guevara1Lindsey R.Sangaralingham23Darrell R.Schroeder2Randall P.Flick1Michael J.Zaccariello4David O.Warner1

doi : 10.1016/j.bja.2021.07.025

Volume 127, Issue 5, November 2021, Pages 722-728

Children's exposure to anaesthesia has been associated with risk of developing attention-deficit/hyperactivity disorder (ADHD). The goal of this study was to determine if selected patient characteristics moderate the association between exposure to anaesthesia and ADHD.

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Morbidity, mortality, and systems safety in non-operating room anaesthesia: a narrative review

Abigail D.Herman1Candace B.Jaruzel2SamLawton3Catherine D.Tobin3Joseph G.Reves3Kenneth R.Catchpole3Myrtede C.Alfred3

doi : 10.1016/j.bja.2021.07.007

Volume 127, Issue 5, November 2021, Pages 729-744

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Outcome measures in solid organ donor management research: a systematic review

Kasia D.Bera12AkshayShah34M. RexEnglish5RutgerPloeg1

doi : 10.1016/j.bja.2021.07.008

Volume 127, Issue 5, November 2021, Pages 745-759

We systematically reviewed published outcome measures across randomised controlled trials (RCTs) of donor management interventions.

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Failure to detect ward hypoxaemia and hypotension: contributions of insufficient assessment frequency and patient arousal during nursing assessments

RemieSaab1Bernie P.Wu12EvaRivas13AndrewChiu1SofiaLozovoskiy1ChaoMa14DongshengYang14AlparslanTuran15Daniel I.Sessler1

doi : 10.1016/j.bja.2021.06.014

Volume 127, Issue 5, November 2021, Pages 760-768

Postoperative hypotension and hypoxaemia are common and often unrecognised. With intermittent nursing vital signs, hypotensive or hypoxaemic episodes might be missed because they occur between scheduled measurements, or because the process of taking vital signs arouses patients and temporarily improves arterial blood pressure and ventilation. We therefore estimated the fraction of desaturation and hypotension episodes that did not overlap nursing assessments and would therefore usually be missed. We also evaluated the effect of taking vital signs on blood pressure and oxygen saturation.

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Voice alerting as a medical alarm modality for next-generation patient monitoring: a randomised international multicentre trial

Tadzio R.Roche1JuliaBraun2Michael T.Ganter3PatrickMeybohm4JohannesHerrmann4KaiZacharowski5Florian J.Raimann5FlorianPiekarski5Donat R.Spahn1Christoph B.Nöthiger1David W.Tscholl1SadiqSaid1

doi : 10.1016/j.bja.2021.07.015

Volume 127, Issue 5, November 2021, Pages 769-777

Acoustic alarms in medical devices are vital for patient safety. State-of-the-art patient monitoring alarms are indistinguishable and contribute to alarm fatigue. There are two promising new sound modalities for vital sign alarms. Auditory icons convey alarms as brief metaphorical sounds, and voice alerts transmit information using a clear-spoken language. We compared how reliably healthcare professionals identified alarms using these two modalities.

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Understanding the performance of a pan-African intervention to reduce postoperative mortality: a mixed-methods process evaluation of the ASOS-2 trial

NicolaVickeryabTimothyStephensbcLeondu ToitadDawidvan StraatengRupertPearsebAlexandraTorborgefLucyRoltfMariechenPuchertaGrahamMartinhBruceBiccardaiASOS-2 Investigators†

doi : 10.1016/j.bja.2021.07.001

Volume 127, Issue 5, November 2021, Pages 778-788

The African Surgical OutcomeS-2 (ASOS-2) trial tested an enhanced postoperative surveillance intervention to reduce postoperative mortality in Africa. We undertook a concurrent evaluation to understand the process of intervention delivery.

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Association between opioid-related deaths and prescribed opioid dose and psychotropic medicines in England: a case-crossover study

Teng-ChouChen12Roger D.Knaggs243Li-ChiaChen1

doi : 10.1016/j.bja.2021.06.049

Volume 127, Issue 5, November 2021, Pages 789-797

Opioid-overdose deaths are associated with poisoning with prescription and illicit opioids in the USA. In contrast, opioid-related deaths (ORDs) in the UK often involve drugs and substances of misuse, and may not be associated with a high dose of prescribed opioids. This study aimed to investigate the association between prescribed opioid dose and ORDs in UK primary care.

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Optimisation of airway management strategies: a prospective before-and-after study on events related to airway management†

Tina H.Pedersen1FlorianUeltschi1TobiasHornshaw1RobertGreif12LorenzTheiler3MarkusHuber4MarenKleine-Brueggeney5

doi : 10.1016/j.bja.2021.07.030

Volume 127, Issue 5, November 2021, Pages 798-806

Poor medical outcomes often result from series of minor events. The present study assessed events related to airway management to determine whether targeted changes to departmental strategies for airway management can reduce the incidence.

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Effect of positive end-expiratory pressure on lung injury and haemodynamics during experimental acute respiratory distress syndrome treated with extracorporeal membrane oxygenation and near-apnoeic ventilation

JoaquinAraos12LeylaAlegria1AlineGarcia1PabloCruces345DagobertoSoto1BenjamínErranz6TatianaSalomon7TaniaMedina5PatricioGarcia8SebastiánDubó9María C.Bachmann1RoqueBasoalto1Emilio D.Valenzuela1MaximilianoRovegno1MagdalenaVera1JaimeRetamal13RodrigoCornejo103GuillermoBugedo13AlejandroBruhn13

doi : 10.1016/j.bja.2021.07.031

Volume 127, Issue 5, November 2021, Pages 807-814

Lung rest has been recommended during extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS). Whether positive end-expiratory pressure (PEEP) confers lung protection during ECMO for severe ARDS is unclear. We compared the effects of three different PEEP levels whilst applying near-apnoeic ventilation in a model of severe ARDS treated with ECMO.

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Ipsilateral and contralateral validation of continuous noninvasive finger blood pressure: does side matter?

Ward H.van der Ven1Sam P.C.Kleinsteuber1Lotte E.Terwindt1JimmySchenk1Björn J.P.van der Ster1Alexander P.J.Vlaar23Markus W.Hollmann13Denise P.Veelo1Rogier V.Immink1

doi : 10.1016/j.bja.2021.07.032

Volume 127, Issue 5, November 2021, Pages e149-e151

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Anaesthetist-administered wrong-side eye blocks: need to reinforce clearer guidelines and site marking

AlyssaChiewCherylSawEdwinSeetChandra M.Kumar

doi : 10.1016/j.bja.2021.07.014

Volume 127, Issue 5, November 2021, Pages e151-e154

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Influence of preterm labour epidural analgesia on neonatal and maternal outcomes: a single-centre retrospective study

YumikoMori1SatoshiToyama23MasakiSato3YokoYamashita3YasuyukiSuzuki3HaruhikoSago4

doi : 10.1016/j.bja.2021.07.017

Volume 127, Issue 5, November 2021, Pages e154-e156

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Impact of parenteral iron within a perioperative pathway on anaemia in patients with oesophagogastric cancer

TaraHughes1†TobiasMacCarthy1†PaulTraynor2FamilaAlagarsamy3John RobertO'Neill2

doi : 10.1016/j.bja.2021.07.022

Volume 127, Issue 5, November 2021, Pages e156-e158

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Micro-research: opening the innovation door to anaesthesiologists and anaesthesia nurses in China

ChaojinChenNingShenXiaoyueLiWeifengYaoZiqingHei

doi : 10.1016/j.bja.2021.08.002

Volume 127, Issue 5, November 2021, Pages e159-e161

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Validation of a translated Quality of Recovery-15 questionnaire in German patients undergoing elective noncardiac surgery

UrsulaKahl1NeringaGebhardt1KatrinBrodersen1ElenaKainz1LeahSchirren1YuanyuanYu1LindaKrause2RegineKlinger1ChristianZöllner1MarleneFischer13

doi : 10.1016/j.bja.2021.07.026

Volume 127, Issue 5, November 2021, Pages e161-e163

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Topical analgesic BENGAY® reduces myocardial infarct size in rodents

Candida L.Goodnough1YunWu12Eric R.Gross1

doi : 10.1016/j.bja.2021.07.029

Volume 127, Issue 5, November 2021, Pages e163-e166

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Intravenous lidocaine attenuates response to cervical dilation for hysteroscopy: a randomised controlled trial

LiliXu1†ChunWang1†ShaobingDai1JianjunShen2XiaopingChen1Warwick D.Ngan Kee3XinzhongChen1

doi : 10.1016/j.bja.2021.07.020

Volume 127, Issue 5, November 2021, Pages e166-e168

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Meta-analysis of randomised controlled trials of perioperative dexmedetomidine to reduce delirium and mortality after cardiac surgery

Robert D.Sanders123JordanWehrman1JoanneIrons12JanDieleman4DavidScott56YahyaShehabi78

doi : 10.1016/j.bja.2021.08.009

Volume 127, Issue 5, November 2021, Pages e168-e170

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Perioperative dexmedetomidine and 5-year survival in patients undergoing cardiac surgery. Reply to Br J Anaesth 2021; 127: e127–8

KePeng12Yue-pingShen3Richard L.ApplegateII2David A.Lubarsky2HongLiu2Fu-HaiJi1

doi : 10.1016/j.bja.2021.07.018

Volume 127, Issue 5, November 2021, Pages e170-e171

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Comparing standard and non-standard videolaryngoscopes in children: methodological issues. Response to Br J Anaesth 2021; 127: e52–e4

JamesPeyton12JohnFiadjoe12Mary L.Stein12RaymondPark12StevenStaffa1DavidZurakowski12PeteKovatsis12

doi : 10.1016/j.bja.2021.08.013

Volume 127, Issue 5, November 2021, Pages e172-e173

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Contralateral sensitisation is not specific for complex regional pain syndrome. Comment on Br J Anaesth 2021; 127: e1–3

Elena K.Enax-Krumova1RalfBaron2Rolf-DetlefTreede3JanVollert234

doi : 10.1016/j.bja.2021.07.019

Volume 127, Issue 5, November 2021, Pages e173-e176

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Crowdsourcing anaesthesia care. Comment on Br J Anaesth 2016; 117: 276–279

The-HungNguyen1Chester G.Chambers2MaqboolDada2

doi : 10.1016/j.bja.2021.07.012

Volume 127, Issue 5, November 2021, Pages e176-e177

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Quantifying the effect of personal protective equipment on speech understanding

AlexanderMalinAndrewDooleyGrainneGarvey

doi : 10.1016/j.bja.2021.08.005

Volume 127, Issue 5, November 2021, Pages e178-e180

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In-hospital mortality rates of critically ill COVID-19 patients in France: a nationwide cross-sectional study of 45 409 ICU patients

AntoineGuillon1EmelineLaurent23LucileGodillon2AntoineKimmoun4LeslieGrammatico-Guillon25

doi : 10.1016/j.bja.2021.08.006

Volume 127, Issue 5, November 2021, Pages e180-e182

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Sepsis in severe COVID-19 is rarely septic shock: a retrospective single-centre cohort study

PietroArina1ValeriaMoro1BeatriceBaso1ChristopherBaxter-Derrington2MervynSinger1

doi : 10.1016/j.bja.2021.08.007

Volume 127, Issue 5, November 2021, Pages e182-e185

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COVID-19: a boost for intensive care authorship?

FilippoSanfilippo1ValeriaDrago2GiovannaBonelli2StefanoTigano2LuigiLa Via12MarinellaAstuto123

doi : 10.1016/j.bja.2021.07.013

Volume 127, Issue 5, November 2021, Pages e185-e187

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An Extraordinary Journey: What Matters at the End of Life, Teik Oh, Elsevier (2021), pp. 236. £19.99. ISBN 978-0-72-954374-3

PaulMyles

doi : 10.1016/j.bja.2021.07.010

Volume 127, Issue 5, November 2021, Pages 815-816

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