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Determination of 11 minerals in children using inductively coupled plasma mass spectrometry
Xiaofeng Li, Chunnan Wang, Yang Wang, Xusheng Zhao & Na Li
doi : 10.1186/s12887-021-02962-z
BMC Pediatrics volume 21, Article number: 483 (2021)
Minerals play an important role in children’s growth and cognition. In this study, our aim was to establish reference intervals of mineral level in Children of Liaoning province (China) and provide a reliable basis for future preventive healthcare guidelines.
Clinical experience of use of percutaneous peripheral arterial cannulation in sick neonates in a developing country
Sachin Shah, Amita Kaul, Shambhavi Mishra & Shridhar Pawale
doi : 10.1186/s12887-021-02943-2
BMC Pediatrics volume 21, Article number: 484 (2021)
Continuous invasive arterial monitoring is necessary in sick neonates needing hemodynamic and ventilatory support. The primary objective of our study was to describe clinical experience with percutaneous peripheral arterial cannulation (PAC) in sick neonates.
The effects of exposure to HIV in neonates at a referral hospital in South Africa
Helena Mellqvist, Robin T. Saggers, Anders Elfvin, Elisabet Hentz & Daynia E. Ballot
doi : 10.1186/s12887-021-02969-6
BMC Pediatrics volume 21, Article number: 485 (2021)
Fewer infants are infected with HIV through mother-to-child transmission, making HIV-exposed but uninfected (HEU) infants a growing population. HIV-exposure seems to affect immunology, early growth and development, and is associated with higher morbidity and mortality rates. Currently, there is a lack of information regarding the clinical effects of HIV-exposure during the neonatal period.
Translation, adaptation and testing of an emergency care satisfaction scale in Swedish pediatric emergency departments
Anne Wennick, Dorota Schoug, Anna Ekwall & Malin Axelsson
doi : 10.1186/s12887-021-02961-0
BMC Pediatrics volume 21, Article number: 486 (2021)
Pediatric healthcare today shows a rising demand for research focusing on children’s perspectives on and consumer satisfaction with the nursing care they receive. Therefore, the purpose of this study was to translate and adapt the Consumer Emergency Care Satisfaction Scale (CECSS), a paper-based, self-administered 19-item questionnaire originally developed in the United States and targeted towards adults, and then test the new version in Swedish pediatric emergency departments.
Treatment device for neonatal birth asphyxia related Hypoxic Ischemic Encephalopathy
Rediet Zewdie, Lidet Getachew, Geremew Dubele, Ababo Oluma, Gedion Israel, Kokeb Dese & Gizeaddis Lamesgin Simegn
doi : 10.1186/s12887-021-02970-z
BMC Pediatrics volume 21, Article number: 487 (2021)
Birth asphyxia is a leading cause of neonatal brain injury, morbidity, and mortality globally. It leads to a multi-organ dysfunction in the neonate and to a neurological dysfunction called Hypoxic Ischemic Encephalopathy (HIE). Cooling therapy is commonly used to slow or stop the damaging effects of birth asphyxia. However, most of the cooling devices used in the healthcare facility do not have a rewarming functionality after cooling therapy. A separate rewarming device, usually a radiant warmer or incubator is used to rewarm the infant after therapy, causing additional burden to the healthcare system and infant families. The objective of this project was, therefore, to design and develop a cost-effective and efficient total body cooling and rewarming device.
Elucidating the context for implementing nonpharmacologic care for neonatal opioid withdrawal syndrome: a qualitative study of perinatal nurses
Clayton J. Shuman, Roxanne Wilson, Katherine VanAntwerp, Mikayla Morgan & Ashley Weber
doi : 10.1186/s12887-021-02955-y
BMC Pediatrics volume 21, Article number: 489 (2021)
Up to 95% of neonates exposed to opioids in utero experience neonatal opioid withdrawal syndrome at birth. Nonpharmacologic approaches (e.g., breastfeeding; rooming-in; skin-to-skin care) are evidence-based and should be implemented. These approaches, especially breastfeeding, rely on engagement of the neonates’ mothers to help deliver them. However, little is known about the structural and social dynamic context barriers and facilitators to implementing maternal-delivered nonpharmacologic care.
How effective is fine motor training in children with ADHD? A scoping review
Miriam Lelong, Annina Zysset, Mirjam Nievergelt, Reto Luder, Ulrich Götz, Christina Schulze & Frank Wieber
doi : 10.1186/s12887-021-02916-5
BMC Pediatrics volume 21, Article number: 490 (2021)
Motor deficiencies are observed in a large number of children with ADHD. Especially fine motor impairments can lead to academic underachievement, low self-esteem and frustration in affected children. Despite these far-reaching consequences, fine motor deficiencies have remained widely undertreated in the ADHD population. The aim of this review was to systematically map the evidence on existing training programs for remediating fine motor impairments in children with ADHD and to assess their effectiveness.
The association between low birth weight and dental caries among 11-to-13-year-old school age children in Ningbo, China
Xiaoyan Weng, Yiting Lou, Ran Tao, Yongzheng Li, Danna Cao, Mengfei Yu, Binbin Ying & Huiming Wang
doi : 10.1186/s12887-021-02968-7
BMC Pediatrics volume 21, Article number: 491 (2021)
The association between low birth weight (LBW) and dental caries is currently unclear. The aim of this study was to investigate the association of LBW with dental caries in permanent teeth in children of Ningbo city.
Anti-HBs levels in children under the age of two years born to HBV carrier mothers after immunoprophylaxis: a multicenter cross-sectional study
Min Jiang, Bo Zhu, Qiang Yao, Haifeng Lou & Xiaohui Zhang
doi : 10.1186/s12887-021-02967-8
BMC Pediatrics volume 21, Article number: 492 (2021)
Serological testing for the presence of Hepatitis B Virus (HBV) markers and anti-HBs titers in infants born to HBsAg positive women is critically important for estimation in immunisation programme.
Poor weight gain and its predictors among preterm neonates admitted at Muhimbili National Hospital in Dar-es-salaam, Tanzania: a prospective cohort study
Victoria Paul Ndembo, Helga Naburi, Rodrick Kisenge, Germana H. Leyna & Candida Moshiro
doi : 10.1186/s12887-021-02971-y
BMC Pediatrics volume 21, Article number: 493 (2021)
Preterm delivery is among the major public health problems worldwide and the leading cause of morbidity and mortality among neonates. Postnatal poor weight gain, which can contribute to mortality, can be influenced by feeding practices, medical complications and quality of care that is provided to these high-risk neonates. This study aimed to investigate the proportion and predictors of poor weight gain among preterm neonates at Muhimbili National Hospital (MNH), from September 2018 to February 2019.
Comparison analysis of childhood body mass index cut-offs in predicting adulthood carotid intima media thickness: Tehran lipid and glucose study
Farhad Hosseinpanah, Amirhosein Seyedhoseinpour, Maryam Barzin, Maryam Mahdavi, Erfan Tasdighi, Pooneh Dehghan, Amin Momeni Moghaddam, Fereidoun Azizi & Majid Valizadeh
doi : 10.1186/s12887-021-02963-y
BMC Pediatrics volume 21, Article number: 494 (2021)
The prevalence of obesity among children and adolescences have been increased, which can consequently increase the prevalence of metabolic and cardiovascular diseases later in life. The objective of this study is to compare the ability of different childhood body mass index cut-offs in prediction of carotid intima media thickness (CIMT) as an indicator of subclinical atherosclerosis.
A cross-sectional, exploratory survey on health-relevant free-time activities and body mass index in preschool children in urban and rural settings of Austria
J. Robatsch, P. Voitl & Susanne C. Diesner-Treiber
doi : 10.1186/s12887-021-02972-x
BMC Pediatrics volume 21, Article number: 495 (2021)
The increasing prevalence of obesity is among the most relevant healthcare issues in Europe. The number of overweight people rises due to lifestyle changes, increased sitting activities, and less physical activity. Prevention in early childhood is paramount to stop this alarming trend.
Body mass index and physical activity in seven-year-old children whose mothers exercised during pregnancy: follow-up of a multicentre randomised controlled trial
Karen Alterhaug Bjøntegaard, Signe Nilssen Stafne, Siv Mørkved, Kjell Åsmund Salvesen & Kari Anne I. Evensen
doi : 10.1186/s12887-021-02952-1
BMC Pediatrics volume 21, Article number: 496 (2021)
There are limited data on long-term outcomes of children whose mothers have followed exercise interventions during pregnancy. The aim of this paper was to investigate whether regular moderate intensity exercise during pregnancy affected the children’s body mass index (BMI) and physical activity (PA) at 7?years of age, and determine the relationship between children’s and mothers’ BMI and PA.
Spatial variation and determinants of childhood anemia among children aged 6 to 59?months in Ethiopia: further analysis of Ethiopian demographic and health survey 2016
Tiruneh Ayele Jember, Destaw Fetene Teshome, Lemma Derseh Gezie & Chilot Desta Agegnehu
doi : 10.1186/s12887-021-02901-y
BMC Pediatrics volume 21, Article number: 497 (2021)
The magnitude of childhood anemia was increased from time to time. Thus, Even if the Ethiopian government applied tremendous efforts, anemia in children continues as a major public health problem. There is limited evidence on the spatial variation of and determinant factors of childhood anemia at the national level. Therefore, this study aimed to explore spatial distribution and determinants of anemia among children aged 6 to 59?months in Ethiopia.
An analysis of the clinical features of children with early congenital Syphilis and Syphilitic Hepatitis
Hongling Yang, Huimin Zhang, Caiying Wang & Lin Pang
doi : 10.1186/s12887-021-02932-5
BMC Pediatrics volume 21, Article number: 498 (2021)
The infection rate of congenital syphilis is gradually increasing, the clinical manifestations of some children with congenital syphilis are abnormal liver function, which is given the clinical diagnosis of syphilitic hepatitis. At present, there are few studies on the clinical features of children with early congenital syphilis combined with syphilitic hepatitis, so we set out to do such a study. We compared the liver function indicators before and after the treatment of syphilis to find the clinical features that can provide guidance for clinical diagnosis and treatment.
Effectiveness of mobile application on changing weight, healthy eating habits, and quality of life in children and adolescents with obesity: a randomized controlled trial
Narueporn Likhitweerawong, Nonglak Boonchooduang, Kulnipa Kittisakmontri, Weerasak Chonchaiya & Orawan Louthrenoo
doi : 10.1186/s12887-021-02980-x
BMC Pediatrics volume 21, Article number: 499 (2021)
A technology-based intervention, such as a mobile application, was a growing interest and potentially effective modality for treating obesity. The study aimed to evaluate the effectiveness of the OBEST, a new mobile/tablet-based application in reducing weight and encouraging healthy eating behaviors and quality of life in children with obesity. The application could assist healthcare professionals to treat children and adolescents with obesity.
Airway injury and pneumomediastinum associated with less invasive surfactant administration in a premature neonate: a case report
Talal Altamimi, Brooke Read, Orlando da Silva & Soume Bhattacharya
doi : 10.1186/s12887-021-02981-w
BMC Pediatrics volume 21, Article number: 500 (2021)
The use of less invasive surfactant administration (LISA)/minimally invasive surfactant therapy (MIST) has increased due to its potential advantage over traditional surfactant delivery methods through an endotracheal tube. Known complications for this procedure include failure of the first attempt at insertion, desaturation, and bradycardia. To the best of our knowledge, this is the first reported case of pneumomediastinum and subcutaneous emphysema following LISA.
The effect of oral ondansetron on QT interval in children with acute gastroenteritis; a retrospective observational study
Heewon Yang, Woochan Jeon, Yura Ko, Sooin Jeong & Jisook Lee
doi : 10.1186/s12887-021-02937-0
BMC Pediatrics volume 21, Article number: 501 (2021)
In mildly to moderately dehydrated patients with acute gastroenteritis (AGE), oral rehydration therapy (ORT) is the treatment of choice. Though ondansetron is a very effective antiemetics and leads to succeed ORT, there have been reports QT prolongation in patients using it. We investigated the effect of oral ondansetron on QT interval in mildly to moderately dehydrated children with AGE.
Concurrent central diabetes insipidus and cerebral salt wasting disease in a post-operative case of craniopharyngioma: a case report
Patel Zeeshan Jameel, Sham Lohiya, Keta Vagha, Tauheed Ahmed, Divya Pujari, Jayant Vagha & Ashish Varma
doi : 10.1186/s12887-021-02982-9
BMC Pediatrics volume 21, Article number: 502 (2021)
Water and electrolyte disorders commonly encountered in children post-surgery involving hypothalamus and posterior pituitary, are central diabetes insipidus, syndrome of inappropriate secretion of anti-diuretic hormone and cerebral salt wasting disease. Delayed diagnosis and inadequate management of such cases may lead to worsened neurological outcomes with a high mortality rate.
Complementary and alternative medicine use among pediatrics in Palestine: a cross-sectional study
Samah W. Al-Jabi, Mariam Khader, Islam Hamarsha, Dina Atallh, Sereen Bani-Odeh, Areen Daraghmeh, Shaima Bani-Mater & Sa’ed H. Zyoud
doi : 10.1186/s12887-021-02985-6
BMC Pediatrics volume 21, Article number: 503 (2021)
Recent use of complementary and alternative medicine (CAM) is growing in children worldwide, so there is a need to evaluate CAM’s use among pediatrics in Palestine. This study aimed to estimate the prevalence of CAM use among a sample of Palestinian children, investigate the factors that affect the use of CAMs, identify the types of CAM used, and assess the purposes of using them.
Colorectal Cancer associated with pediatric inflammatory bowel disease: a case series
Min Jee Kim, Jae Sung Ko, Minsoo Shin, Jong Woo Hahn, Soo Young Moon, Hyun Young Kim & Jin Soo Moon
doi : 10.1186/s12887-021-02966-9
BMC Pediatrics volume 21, Article number: 504 (2021)
Inflammatory bowel disease (IBD) is associated with an increased risk of Colorectal cancer (CRC), and its most important risk factors are the duration and extent of the disease. Pediatric-onset inflammatory bowel disease has a tendency for a more extensive, more severe, and longer predicted disease duration than adult-onset inflammatory bowel disease. This study aimed to identify the clinical characteristics of patients with CRC related to pediatric-onset IBD and consider the appropriateness of current surveillance endoscopy recommendations for the detection of premalignant lesions and early-stage CRC.
Game-based training of selective voluntary motor control in children and youth with upper motor neuron lesions: protocol for a multiple baseline design study
Annina Fahr, Andrina Kläy, Larissa S. Coka & Hubertus J. A. van Hedel
doi : 10.1186/s12887-021-02983-8
BMC Pediatrics volume 21, Article number: 505 (2021)
Impairments of selective control of joint movements can have consequences for many activities of daily life, but there are only a few interventions to improve selective voluntary motor control (SVMC). We have developed a treatment option to specifically enhance SVMC exploiting the advantages of interactive computer play technology. It targets SVMC by training selective activation of a muscle or a selective joint movement while it provides immediate feedback about involuntary muscle activations/movements at an (unwanted) joint. This study aims to investigate the effectiveness of this game-based intervention to enhance SVMC in children and youth with upper motor neuron lesions.
Prolonged rectal shedding of SARS-CoV-2 in a 22-day-old-neonate: a case report
Julie Niemann Holm-Jacobsen, Julia Helena Vonasek, Søren Hagstrøm, Mette Line Donneborg & Suzette Sørensen
doi : 10.1186/s12887-021-02976-7
BMC Pediatrics volume 21, Article number: 506 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the novel coronavirus disease 2019 (COVID-19), which is characterized by a diverse clinical picture. Children are often asymptomatic or experience mild symptoms and have a milder disease course compared to adults. Rectal shedding of SARS-CoV-2 has been observed in both adults and children, suggesting the fecal-oral route as a potential route of transmission. However, only a few studies have investigated this in neonates. We present a neonate with a mild disease course and prolonged rectal SARS-CoV-2 shedding.
Novel type of references for weight aligned for onset of puberty – using the QEPS growth model
Kerstin Albertsson-Wikland, Aimon Niklasson, Lars Gelander, Anton Holmgren & Andreas F. M. Nierop
doi : 10.1186/s12887-021-02954-z
BMC Pediatrics volume 21, Article number: 507 (2021)
Growth references are traditionally constructed relative to chronological age, despite inter-individual variations in pubertal timing. A new type of height reference was recently developed allowing growth to be aligned based on onset of pubertal height growth. We here aim to develop a corresponding reference for pubertal weight.
Development and psychometric properties of the Knowledge and Attitudes to Mental Health Scales (KAMHS): a psychometric measure of mental health literacy in children and adolescents
Nicola J. Simkiss, Nicola S. Gray, Chris Dunne & Robert J. Snowden
doi : 10.1186/s12887-021-02964-x
BMC Pediatrics volume 21, Article number: 508 (2021)
Adolescence is a crucial period for the acquisition of good mental health behaviours, which are the foundation for health and wellbeing in later life. Improved knowledge about mental health and improved help-seeking behaviours have been shown to lead to better mental health outcomes. Mental health literacy (MHL) is multifaceted (e.g., knowledge about symptoms, the stigma around mental health, good mental health practices, etc.). Measures are needed that can assess these different aspects of MHL. Measurement of mental health literacy is currently limited due to a lack of reported psychometric instruments with known psychometric properties. Given that most mental health problems start in early adolescence, a scale is needed that is reliable and valid in this age group.
Obesity is a risk factor for central precocious puberty: a case-control study
Gaiyan Liu, Jinxin Guo, Xuejing Zhang, Yu Lu, Junjie Miao & Hongmei Xue
doi : 10.1186/s12887-021-02936-1
BMC Pediatrics volume 21, Article number: 509 (2021)
Obesity is an important underlying cause of central precocious puberty (CPP), but previous large studies are flawed by using just age and breast examination to diagnose CPP. We aimed to determine whether overweight and obesity in childhood increases hormonally diagnosed CPP.
Evaluation of Healthy South Texas Asthma Program on improving health outcomes and reducing health disparities among the underserved Hispanic population: using the RE-AIM model
Genny Carrillo, Taehyun Roh, Juha Baek, Betty Chong-Menard & Marcia Ory
doi : 10.1186/s12887-021-02991-8
BMC Pediatrics volume 21, Article number: 510 (2021)
In the United States, childhood asthma prevalence is higher among low-income communities and Hispanic populations. Previous studies found that asthma education could improve health and quality of life, especially in vulnerable populations lacking healthcare access. This study aims to describe Healthy South Texas Asthma Program (HSTAP), an evidence-based asthma education and environmental modification program in South Texas, and evaluate its associations with health-related outcomes among Hispanic children with asthma and their families.
Retinal vein occlusion with cerebral infarction in a preterm neonate: a case report
Xiuyu Zhu, Xiaojing Cai, Xiaohong Zhou, Yian Li & Chenhao Yang
doi : 10.1186/s12887-021-02989-2
BMC Pediatrics volume 21, Article number: 511 (2021)
Retinal vein occlusion (RVO) is a common disease that causes blindness in elderly patients, and cerebral infarction is also a severe disorder impairing the health of individuals. Both diseases are not common in neonates and are related to thrombosis. To date, only one case of simultaneous occurrence of RVO with intracranial haemorrhage in a full-term neonate has been reported.
Utilization of psychotropic medications in children with FASD: a retrospective review
Michael-Roy R. Durr, Susan Petryk, Mansfield Mela, Andrea DesRoches, Mackenzie Wekerle & Sanjida Newaz
doi : 10.1186/s12887-021-02986-5
BMC Pediatrics volume 21, Article number: 512 (2021)
Fetal Alcohol Spectrum Disorder (FASD) is a neurodevelopmental condition resulting from pre-natal alcohol exposure. In Canada, an estimated 1.4-4% of newborns are affected by FASD. FASD is often associated with behavioural comorbidities and many individuals require psychotropic medication. However, to date there are no FASD specific guidelines for prescribing medication. Recently, Mela and colleagues described four behavioural symptom clusters commonly seen in FASD with suggested pharmacologic treatment for each cluster within an algorithm. The primary objective was to compare the proposed treatment algorithm retrospectively to actual treatment in a real-world FASD pediatric practice. The secondary objective was to refine the description of symptom clusters which will be targeted with treatment.
Why parents agree or disagree for minimally invasive tissue sampling (MITS) to identify causes of death in under-five children and stillbirth in North India: a qualitative study
Manoja Kumar Das, Narendra Kumar Arora, Pradeep Debata, Harish Chellani, Reeta Rasaily, Harsha Gaikwad, K. R. Meena, Gurkirat Kaur, Prikanksha Malik, Shipra Joshi & Mahisha Kumari
doi : 10.1186/s12887-021-02993-6
BMC Pediatrics volume 21, Article number: 513 (2021)
Information on exact causes of death and stillbirth are limited in low and middle income countries. Minimally invasive tissue sampling (MITS) is increasingly practiced in place of autopsy across several settings. A formative research documented the experiences of counselling and consenting for MITS in north India.
Determinants of the type of health care sought for symptoms of Acute respiratory infection in children: analysis of Ghana demographic and health surveys
Leslie Danquah, Prince Michael Amegbor & Dawit Getnet Ayele
doi : 10.1186/s12887-021-02990-9
BMC Pediatrics volume 21, Article number: 514 (2021)
Globally, acute respiratory infection (ARI) is a leading cause of infant and childhood morbidity and mortality. Currently, it is estimated that 50 million cases of childhood ARI are untreated. In this study, we identified determinants of the type of treatment sought for symptoms of childhood acute respiratory infection (ARI), including non-treatment, amongst a nationally representative sample of children under five years in Ghana.
Time to death and its determinants among under-five children in Sub-Saharan Africa using the recent (2010–2018) demographic and health survey data: country-based shared frailty analyses
Desalegn Tesfa, Sofonyas Abebaw Tiruneh, Melkalem Mamuye Azanaw, Alemayehu Digssie Gebremariam, Melaku Tadege Engdaw, Belayneh Kefale, Bedilu Abebe & Tsion Dessalegn
doi : 10.1186/s12887-021-02950-3
BMC Pediatrics volume 21, Article number: 515 (2021)
Substantial global progress has been made in reducing under-five mortality since 1990, yet progress is insufficient to meet the sustainable development goal of 2030 which calls for ending preventable child deaths. There are disproportional survivals among children in the world. Therefore, the study aimed to assess the Survival status of under-five mortality and determinants in Sub-Saharan African Countries using the recent DHS data.
Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with covid-19 in critically ill patients: an observational multicenter study (MISCO study)
Lorena Acevedo, Byron Enrique Piñeres-Olave, Laura Fernanda Niño-Serna, Liliana Mazzillo Vega, Ivan Jose Ardila Gomez, Shayl Chacón, Juan Camilo Jaramillo-Bustamante, Hernando Mulett-Hoyos, Otto González-Pardo, Eliana Zemanate, Ledys Izquierdo, Jaime Piracoca Mejìa, Jose Luis Junco González, Beatriz Giraldo Duran, Carolina Bonilla Gonzalez, Helen Preciado, Rafael Orozco Marun, Martha I Alvarez-Olmos, Carolina Giraldo Alzate, Jorge Rojas, Juan Carlos Salazar-Uribe, Juan-Manuel Anaya & Jaime Fernández-Sarmiento
doi : 10.1186/s12887-021-02974-9
BMC Pediatrics volume 21, Article number: 516 (2021)
The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes the clinical characteristics of MIS-C in critically ill children in middle-income countries and the factors associated with the rate of mortality and patients with critical outcomes.
Protocol: Pentoxifylline optimal dose finding trial in preterm neonates with suspected late onset sepsis (PTX-trial)
Serife Kurul, H. Rob Taal, Robert B. Flint, Jan Mazela, Irwin K. M. Reiss, Karel Allegaert & Sinno H. P. Simons
doi : 10.1186/s12887-021-02975-8
BMC Pediatrics volume 21, Article number: 517 (2021)
Late onset sepsis is a leading cause of death and morbidity in preterm infants. Despite optimal antibiotic treatment, sepsis related mortality and morbidity is still high. Pentoxifylline (PTX) is a methylxanthine with promising immunomodulatory properties, which can be used as an additional therapy next to antibiotics in preterm infants. PTX is increasingly used off-label in neonatal intensive care units, however up till now no dose finding study has been done for PTX in this specific population. The aim of this study (PTX-trial) is to determine the optimal dose of PTX in preterm infants (gestational age < 30 weeks) with (suspected) late onset sepsis. Dose finding in this particular population is unique, since for most drugs used in neonates the optimal dosage has not been investigated in phase II dose-seeking studies.
Newborn low birth weight: do socio-economic inequality still persist in India?
Prem Shankar Mishra, Debashree Sinha, Pradeep Kumar, Shobhit Srivastava & Rahul Bawankule
doi : 10.1186/s12887-021-02988-3
BMC Pediatrics volume 21, Article number: 518 (2021)
The incidence of preterm birth and subsequent low birth weight (LBW) are vital global public health issues. It contributes to high infant and child mortality in the early stages of life and later on in adult life; it increases the risk for non-communicable diseases. The study aims to understand the socio-economic status-related inequality for LBW among children in India. It hypothesises that there is no association between the socio-economic status of the household and the newborn’s LBW in India.
Fatigue in children and adolescents perinatally infected with human immunodeficiency virus: an observational study
A. M. ter Haar, M. M. Nap-van der Vlist, M. Van den Hof, S. L. Nijhof, R. R. L. van Litsenburg, K. J. Oostrom & D. Pajkrt
doi : 10.1186/s12887-021-02977-6
BMC Pediatrics volume 21, Article number: 519 (2021)
Fatigue is common among adults living with human immunodeficiency virus (HIV) as well as children with a chronic disease (CCD). Fatigue can have disastrous effects on health status, including health related quality of life (HRQOL). Even so, fatigue is underexplored in children and adolescents perinatally infected with HIV (PHIV+) in the Netherlands. The objective of this observational study is to explore fatigue in PHIV+ and its association with their HRQOL.
Transmission of cytomegalovirus via breast milk in low birth weight and premature infants: a systematic review and meta-analysis
Xiaolin Hu, Wei Hu, Xuan Sun, Ling Chen & Xiaoping Luo
doi : 10.1186/s12887-021-02984-7
BMC Pediatrics volume 21, Article number: 520 (2021)
This study aimed to investigate the transmission of cytomegalovirus (CMV) via breast milk in low birth weight (LBW) and premature infants and its effects.
Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
Guilang Zheng, Jiaxing Wu, Peiling Chen, Yan Hu, Huiqiong Zhang, Jing Wang, Hanshi Zeng, Xufeng Li, Yueyu Sun, Gang Xu, Shusheng Wen, Jianzheng Cen, Jimei Chen, Yuxiong Guo & Jian Zhuang
doi : 10.1186/s12887-021-02935-2
BMC Pediatrics volume 21, Article number: 521 (2021)
To evaluate trends in the in-hospital mortality rate for pediatric cardiac surgery procedures between 2005 and 2017 in our center, and to discuss the mortality characteristics of children’s CHD after thoracotomy.
Effects of minimally invasive and traditional surgeries on the quality of life of children with congenital heart disease: a retrospective propensity score-matched study
Hui Tan, Erjia Huang, Xicheng Deng, Dongping Li & Shayuan Ouyang
doi : 10.1186/s12887-021-02978-5
BMC Pediatrics volume 21, Article number: 522 (2021)
The focus of clinical care after treating congenital heart disease (CHD) has shifted from saving patients’ lives to improving their quality of life. This study aimed to examine the influence of minimally invasive and traditional surgeries on the quality of life of children with CHD.
Hypospadias: clinical approach, surgical technique and long-term outcome
Pier Luca Ceccarelli, Laura Lucaccioni, Francesca Poluzzi, Anastasia Bianchini, Diego Biondini, Lorenzo Iughetti & Barbara Predieri
doi : 10.1186/s12887-021-02941-4
BMC Pediatrics volume 21, Article number: 523 (2021)
Hypospadias is one of the most common congenital abnormalities in male newborn. There is no universal approach to hypospadias surgical repair, with more than 300 corrective procedures described in current literature. The reoperation rate within 6–12?months of the initial surgery is most frequently used as an outcome measure. These short-term outcomes may not reflect those encountered in adolescence and adult life. This study aims to identify the long-term cosmetic, functional and psychosexual outcomes.
Testing positive pressure delivered from commercial and WHO-style pediatric bubble CPAP devices
Nicholas A. Ettinger, Nathan Serazin, Richard Nguyen, Jennifer Werdenberg, Minke Huibers & Susan Torrey
doi : 10.1186/s12887-021-03006-2
BMC Pediatrics volume 21, Article number: 524 (2021)
Low-cost commercial bCPAP devices have been deployed in resource-limited settings to treat neonatal respiratory failure. The use of these devices has increased access to pediatric respiratory support for infants. However, constrained resources may result in substitution of recommended consumables and/or use in older age groups. We hypothesized that commercially available bCPAP devices, the standard WHO-style device and various improvised adaptations would all generate effective, safe positive pressure at the patient interface.
Prevalence and associated factors of perinatal asphyxia in newborns admitted to neonatal intensive care unit at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, Ethiopia
Addisu Ginbu Dubie, Mehretie Kokeb, Abraham Tarkegn Mersha & Chilot Desta Agegnehu
doi : 10.1186/s12887-021-03019-x
BMC Pediatrics volume 21, Article number: 525 (2021)
Perinatal asphyxia is one of the leading causes of neonatal mortality and morbidity in Ethiopia. Understanding associated factors of perinatal asphyxia are important to identify vulnerable groups and to improve care during the perinatal period. Thus, this study aimed to assess the prevalence and associated factors of perinatal asphyxia among newborns admitted to NICU at the Gondar University Comprehensive Specialized Hospital Northwest Ethiopia, Ethiopia.
Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
Yao Lin, Lijun Wang, Aijie Li, Hongwei Zhang & Lin Shi
doi : 10.1186/s12887-021-02979-4
BMC Pediatrics volume 21, Article number: 526 (2021)
Kawasaki disease (KD) is an acute febrile vasculitis that often occurs in children under 5?years. Ptosis and muscle weakness associated with KD are rarely documented.
Outcome measures for assessing change over time in studies of symptomatic children with hypermobility: a systematic review
Muhammad Maarj, Andrea Coda, Louise Tofts, Cylie Williams, Derek Santos & Verity Pacey
doi : 10.1186/s12887-021-03009-z
BMC Pediatrics volume 21, Article number: 527 (2021)
Generalised joint hypermobility (GJH) is highly prevalent among children and associated with symptoms in a fifth with the condition. This study aimed to synthesise outcome measures in interventional or prospective longitudinal studies of children with GJH and associated lower limb symptoms.
Major heart defects: the diagnostic evaluations of first-year-olds
Jan Pavlicek, Eva Klaskova, Sabina Kapralova, Alzbeta Moravova Palatova, Alicja Piegzova, Richard Spacek & Tomas Gruszka
doi : 10.1186/s12887-021-02997-2
BMC Pediatrics volume 21, Article number: 528 (2021)
Severe or critical congenital heart defects (CHDs) constitute one third of the heart defect cases detected only after birth. These prenatally unrecognised defects usually manifest as cyanotic or acyanotic lesions and are diagnosed postnatally at various times. The aim of the study was to identify their clinical symptoms and determine individual risk periods for CHD manifestation.
“Childhood Anemia in India: an application of a Bayesian geo-additive model”
Holendro Singh Chungkham, Strong P. Marbaniang & Pralip Kumar Narzary
doi : 10.1186/s12887-021-03008-0
BMC Pediatrics volume 21, Article number: 529 (2021)
The geographical differences that cause anaemia can be partially explained by the variability in environmental factors, particularly nutrition and infections. The studies failed to explain the non-linear effect of the continuous covariates on childhood anaemia. The present paper aims to investigate the risk factors of childhood anaemia in India with focus on geographical spatial effect.
Primary breast lymphoma of childhood: a case report and review of literature
Giulia A. Restivo, Marta Pillon, Lara Mussolin, Clara Mosa, Angela Guarina, Angela Trizzino, Salvatore Ialuna, Elisa Carraro, Emanuele S.G. D’Amore, Giovanna Russo, Caterina Elia, Maurizio Mascarin, Adriana Zangara, Paolo D’Angelo & Piero Farruggia
doi : 10.1186/s12887-021-03002-6
BMC Pediatrics volume 21, Article number: 530 (2021)
Primary breast lymphoma (PBL) is an extremely rare neoplasm in children; by definition, it manifests in the breast without evidence of lymphoma elsewhere, except ipsilateral axillary nodes.
Management of pleural empyema in a 12-year-old obese patient with COVID-19: a pediatric case report
Reza Abbasi, Farnaz Sadat Javanmardi, Ahmad Mokhtari, Parisa Hosseinpour, Reza Shahriarirad & Kamyar Ebrahimi
doi : 10.1186/s12887-021-03007-1
BMC Pediatrics volume 21, Article number: 531 (2021)
With the ongoing coronavirus disease (COVID-19) pandemic, along with the development of new mutations of the virus and an increase in the number of cases among pediatrics, physicians should be aware and alerted on the atypical presentations of the disease, especially in less expected individuals.
Determinants of diarrheal diseases among under five children in Jimma Geneti District, Oromia region, Ethiopia, 2020: a case-control study
Dejene Mosisa, Mecha Aboma, Teka Girma & Abera Shibru
doi : 10.1186/s12887-021-03022-2
BMC Pediatrics volume 21, Article number: 532 (2021)
Globally, in 2017, there were nearly 1.7 billion cases of childhood diarrheal diseases, and it is the second most important cause of morbidity and mortality among under-five children in low-income countries, including Ethiopia. Sanitary conditions, poor housing, an unsanitary environment, insufficient safe water supply, cohabitation with domestic animals that may carry human pathogens, and a lack of food storage facilities, in combination with socioeconomic and behavioral factors, are common causes of diarrhea disease and have had a significant impact on diarrhea incidence in the majority of developing countries.
