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FMT for psychiatric disorders: Following the brown brick road into the future
Jessica E. Green,Michael Berk,Amy Loughman,Wolfgang Marx,David Castle,Amelia J. McGuinness,John F. Cryan,Andrew A. Nierenberg,Eugene Athan,Christopher Hair,Felice Jacka
doi : 10.1111/bdi.13124
Volume 23, Issue 7 p. 651-655
Why we need a more sociable approach to bipolar disorder and how we can make it happen
Fiona Lobban
doi : 10.1111/bdi.13134
Volume 23, Issue 7 p. 656-658
Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force
Ralph Kupka,Anne Duffy,Jan Scott,Jorge Almeida,Vicent Balanzá-Martínez,Boris Birmaher,David J. Bond,Elisa Brietzke,Ines Chendo,Benicio N. Frey,Iria Grande,Danella Hafeman,Tomas Hajek,Manon Hillegers,Marcia Kauer-Sant’Anna,Rodrigo B. Mansur,Afra van der Markt,Robert Post,Mauricio Tohen,Hailey Tremain,Gustavo Vazquez,Eduard Vieta,Lakshmi N. Yatham,Michael Berk,Martin Alda,Flávio Kapczinski
doi : 10.1111/bdi.13105
Volume 23, Issue 7 p. 659-678
Clinical staging is widely used in medicine to map disease progression, inform prognosis, and guide treatment decisions; in psychiatry, however, staging remains a hypothetical construct. To facilitate future research in bipolar disorders (BD), a well-defined nomenclature is needed, especially since diagnosis is often imprecise with blurred boundaries, and a full understanding of pathophysiology is lacking.
Saliva testing as a means to monitor therapeutic lithium levels in patients with psychiatric disorders: Identification of clinical and environmental covariates, and their incorporation into a prediction model
Georgia M. Parkin,Michael J. McCarthy,Soe H. Thein,Hillary L. Piccerillo,Nisha Warikoo,Douglas A. Granger,Elizabeth A. Thomas
doi : 10.1111/bdi.13128
Volume 23, Issue 7 p. 679-688
The narrow therapeutic window of lithium medications necessitates frequent serum monitoring, which can be expensive and inconvenient for the patient. Compared to blood, saliva collection is easier, non-invasive, requires less processing, and can be done without the need for trained personnel. This study investigated the utility of longitudinal salivary lithium level monitoring.
Alterations in plasma kynurenine pathway metabolites in children and adolescents with bipolar disorder and unaffected offspring of bipolar parents: A preliminary study
Deborah Benevenuto,Kirti Saxena,Gabriel R. Fries,Samira S. Valvassori,Ramandeep Kahlon,Johanna Saxena,Sherin Kurian,Cristian P. Zeni,Iram F. Kazimi,Giselli Scaini,Jair C. Soares,João Quevedo
doi : 10.1111/bdi.13027
Volume 23, Issue 7 p. 689-696
There has been growing scientific evidence in recent years that bipolar disorder (BD) is associated with alterations in the kynurenine (KYN) pathway. However, many of these studies have been limited by their focus on adults. Thus, this preliminary study investigated differences in the peripheral levels of KYN metabolites in children and adolescents with BD, unaffected offspring of parents with BD, and healthy controls (HCs).
A 52-week prophylactic randomised control trial of omega-3 polyunsaturated fatty acids in bipolar disorder
Genevieve McPhilemy,Fintan Byrne,Mairead Waldron,Joseph R. Hibbeln,John Davis,Colm McDonald,Brian Hallahan
doi : 10.1111/bdi.13037
Volume 23, Issue 7 p. 697-706
Previous work suggests supplementation with omega-3 polyunsaturated fatty acids (PUFAs) may improve mood symptoms in bipolar disorder (BD) although findings remain unclear. In this study, we assess the efficacy of omega-3 PUFA administration for prophylaxis in BD using a clinical trial design over 52-weeks (ClinicalTrials.gov Identifier: NCT04210804).
N-acetylcysteine as an adjunctive treatment for bipolar depression: A systematic review and meta-analysis of randomized controlled trials
Fabiano G. Nery,Wenbin Li,Melissa P. DelBello,Jeffrey A. Welge
doi : 10.1111/bdi.13039
Volume 23, Issue 7 p. 707-714
Previous studies and meta-analyses suggested that N-acetylcysteine (NAC) was superior to placebo in improving depression in bipolar disorder. However, more recent data, including two larger trials, found that NAC was no more effective than placebo. We conducted a meta-analysis to appraise the possible efficacy of NAC in treating bipolar depression.
Long-term lithium therapy and risk of chronic kidney disease in bipolar disorder: A historical cohort study
Mehak Pahwa,Boney Joseph,Nicolas A. Nunez,Gregory D. Jenkins,Colin L. Colby,Kianoush B. Kashani,Marin Veldic,Katherine M. Moore,Hannah K. Betcher,Aysegul Ozerdem,Alfredo B. Cuellar-Barboza,Susan L. McElroy,Joanna M. Biernacka,Mark A. Frye,Balwinder Singh
doi : 10.1111/bdi.13052
Volume 23, Issue 7 p. 715-723
Long-term lithium therapy (LTLT) has been associated with kidney insufficiency in bipolar disorder (BD). We aimed to investigate the risk factors of chronic kidney disease (CKD) development and progression among BD patients receiving LTLT.
Commentary on Lewy body dementia in an elderly patient with bipolar disorder: Challenges and treatment options
Paula Villela Nunes,Camila Nascimento,Beny Lafer
doi : 10.1111/bdi.13108
Volume 23, Issue 7 p. 724-725
Lithium as a first-step option for acute phase pharmacotherapy of bipolar depression
Sune Puggaard Vogt Straszek,René E. Nielsen,Zoltan Kovacs,Rasmus W. Licht
doi : 10.1111/bdi.13113
Volume 23, Issue 7 p. 726-727
Ketamine for treatment-resistant bipolar depression—need for more data!
Balwinder Singh,Jennifer L. Vande Voort,Simon Kung
doi : 10.1111/bdi.13129
Volume 23, Issue 7 p. 728-729
Omega-3 fatty acids for treating residual depressive symptoms in adult patients with bipolar disorder: A systematic review and meta-analysis of double-blind randomized, placebo-controlled trials
Taro Kishi,Kenji Sakuma,Makoto Okuya,Masashi Ikeda,Nakao Iwata
doi : 10.1111/bdi.13115
Volume 23, Issue 7 p. 730-731
Why might some with a bipolar disorder turn wine into water?
Gordon Parker
doi : 10.1111/bdi.13121
Volume 23, Issue 7 p. 732-732
An episode of mania following self-reported ingestion of psilocybin mushrooms in a woman previously not diagnosed with bipolar disorder: A case report
Holly M. Hendin,Andrew D. Penn
doi : 10.1111/bdi.13095
Volume 23, Issue 7 p. 733-735
Lewy body dementia in an elderly patient with bipolar disorder: Challenges and treatment options
Mohsen Khosravi
doi : 10.1111/bdi.13079
Volume 23, Issue 7 p. 736-739
